Motif ID: Gcm1

Z-value: 0.473


Transcription factors associated with Gcm1:

Gene SymbolEntrez IDGene Name
Gcm1 ENSMUSG00000023333.7 Gcm1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gcm1mm10_v2_chr9_+_78051938_78051958-0.075.9e-01Click!


Activity profile for motif Gcm1.

activity profile for motif Gcm1


Sorted Z-values histogram for motif Gcm1

Sorted Z-values for motif Gcm1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gcm1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr11_-_6065538 5.235 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr7_+_46396439 3.434 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr13_-_100108337 2.346 ENSMUST00000180822.1
 BC001981
cDNA sequence BC001981
chr14_-_19977249 1.985 ENSMUST00000160013.1
 Gng2
guanine nucleotide binding protein (G protein), gamma 2
chr4_-_136956784 1.857 ENSMUST00000030420.8
 Epha8
Eph receptor A8
chr16_-_91597636 1.818 ENSMUST00000023686.8
 Tmem50b
transmembrane protein 50B
chrX_+_73503074 1.812 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
 Atp2b3


ATPase, Ca++ transporting, plasma membrane 3


chr13_+_8202860 1.776 ENSMUST00000064473.6
 Adarb2
adenosine deaminase, RNA-specific, B2
chr17_+_8311101 1.654 ENSMUST00000154553.1
 Sft2d1
SFT2 domain containing 1
chr11_-_75454656 1.632 ENSMUST00000173320.1
 Wdr81
WD repeat domain 81
chr5_-_110343009 1.632 ENSMUST00000058016.9
ENSMUST00000112478.3
 P2rx2

purinergic receptor P2X, ligand-gated ion channel, 2

chr1_-_79761752 1.603 ENSMUST00000113512.1
ENSMUST00000113513.1
ENSMUST00000113515.1
ENSMUST00000113514.1
ENSMUST00000113510.1
ENSMUST00000113511.1
ENSMUST00000048820.7
 Wdfy1






WD repeat and FYVE domain containing 1






chr11_+_116918844 1.482 ENSMUST00000103027.3
 Mgat5b
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr19_+_6400523 1.388 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
 Rasgrp2



RAS, guanyl releasing protein 2



chr11_-_60352869 1.367 ENSMUST00000095254.5
ENSMUST00000102683.4
ENSMUST00000093048.6
ENSMUST00000093046.6
ENSMUST00000064019.8
ENSMUST00000102682.4
 Tom1l2





target of myb1-like 2 (chicken)





chr2_+_96318014 1.357 ENSMUST00000135431.1
ENSMUST00000162807.2
 Lrrc4c

leucine rich repeat containing 4C

chr13_+_8202922 1.223 ENSMUST00000123187.1
 Adarb2
adenosine deaminase, RNA-specific, B2
chr19_+_46761578 1.134 ENSMUST00000077666.4
ENSMUST00000099373.4
 Cnnm2

cyclin M2

chr11_+_101246960 1.111 ENSMUST00000107282.3
 Ramp2
receptor (calcitonin) activity modifying protein 2
chr9_+_70656248 1.022 ENSMUST00000098589.2
 Gm10642
predicted gene 10642
chr3_-_69598822 1.003 ENSMUST00000061826.1
 B3galnt1
UDP-GalNAc:betaGlcNAc beta 1,3-galactosaminyltransferase, polypeptide 1
chr7_+_4922251 1.002 ENSMUST00000047309.5
 Nat14
N-acetyltransferase 14
chr10_-_76345254 1.001 ENSMUST00000036033.7
ENSMUST00000160048.1
ENSMUST00000105417.3
 Dip2a


DIP2 disco-interacting protein 2 homolog A (Drosophila)


chr11_-_106613370 0.996 ENSMUST00000128933.1
 Tex2
testis expressed gene 2
chr9_-_70657121 0.989 ENSMUST00000049031.5
 Fam63b
family with sequence similarity 63, member B
chr7_-_99182681 0.959 ENSMUST00000033001.4
 Dgat2
diacylglycerol O-acyltransferase 2
chr13_+_100107997 0.909 ENSMUST00000142155.1
ENSMUST00000022145.8
ENSMUST00000132053.1
 Serf1


small EDRK-rich factor 1


chr10_-_13868779 0.906 ENSMUST00000105534.3
 Aig1
androgen-induced 1
chr5_-_35105691 0.874 ENSMUST00000030986.8
 Lrpap1
low density lipoprotein receptor-related protein associated protein 1
chr7_-_101011976 0.833 ENSMUST00000178340.1
ENSMUST00000037540.3
 P2ry2

purinergic receptor P2Y, G-protein coupled 2

chr7_+_119900099 0.827 ENSMUST00000106516.1
 Lyrm1
LYR motif containing 1
chr13_+_100108155 0.785 ENSMUST00000129014.1
 Serf1
small EDRK-rich factor 1
chr7_-_29906524 0.782 ENSMUST00000159920.1
ENSMUST00000162592.1
 Zfp27

zinc finger protein 27

chr16_-_3907651 0.663 ENSMUST00000177221.1
ENSMUST00000177323.1
 1700037C18Rik

RIKEN cDNA 1700037C18 gene

chr16_+_36875119 0.655 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
 Golgb1


Golgb1
golgi autoantigen, golgin subfamily b, macrogolgin 1


golgi autoantigen, golgin subfamily b, macrogolgin 1
chr17_+_25471564 0.649 ENSMUST00000025002.1
 Tekt4
tektin 4
chr8_+_91070052 0.618 ENSMUST00000034091.7
 Rbl2
retinoblastoma-like 2
chr18_-_39487096 0.539 ENSMUST00000097592.2
ENSMUST00000115571.1
 Nr3c1

nuclear receptor subfamily 3, group C, member 1

chr2_+_169633517 0.519 ENSMUST00000109157.1
 Tshz2
teashirt zinc finger family member 2
chr6_-_113501818 0.414 ENSMUST00000101059.1
 Prrt3
proline-rich transmembrane protein 3
chr17_+_24696234 0.369 ENSMUST00000019464.7
 Noxo1
NADPH oxidase organizer 1
chr14_+_55578360 0.360 ENSMUST00000174259.1
ENSMUST00000174563.1
ENSMUST00000089619.6
ENSMUST00000172738.1
 Psme1



proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)



chr7_+_131966446 0.338 ENSMUST00000045840.4
 Gpr26
G protein-coupled receptor 26
chr11_-_121354337 0.291 ENSMUST00000106110.3
ENSMUST00000136797.1
ENSMUST00000026173.6
 Wdr45b


WD repeat domain 45B


chr11_-_98149551 0.281 ENSMUST00000103143.3
 Fbxl20
F-box and leucine-rich repeat protein 20
chr12_+_8674224 0.248 ENSMUST00000111122.2
 Pum2
pumilio 2 (Drosophila)
chr11_-_35980473 0.246 ENSMUST00000018993.6
 Wwc1
WW, C2 and coiled-coil domain containing 1
chr10_-_71285234 0.232 ENSMUST00000020085.6
 Ube2d1
ubiquitin-conjugating enzyme E2D 1
chr17_-_6948283 0.194 ENSMUST00000024572.9
 Rsph3b
radial spoke 3B homolog (Chlamydomonas)
chr2_+_48814109 0.170 ENSMUST00000063886.3
 Acvr2a
activin receptor IIA
chr14_-_66213552 0.138 ENSMUST00000178730.1
 Ptk2b
PTK2 protein tyrosine kinase 2 beta
chr17_-_32788284 0.138 ENSMUST00000159086.2
 Zfp871
zinc finger protein 871
chr12_+_8674129 0.137 ENSMUST00000111123.2
ENSMUST00000178015.1
ENSMUST00000020915.3
 Pum2


pumilio 2 (Drosophila)


chr14_+_32201937 0.123 ENSMUST00000163350.1
ENSMUST00000170840.1
ENSMUST00000022470.8
ENSMUST00000171279.1
 Parg



poly (ADP-ribose) glycohydrolase



chr2_-_39226343 0.103 ENSMUST00000028087.3
 Ppp6c
protein phosphatase 6, catalytic subunit
chr13_-_95250166 0.098 ENSMUST00000162153.1
ENSMUST00000160957.2
ENSMUST00000159598.1
ENSMUST00000162412.1
 Pde8b



phosphodiesterase 8B



chr9_+_107580117 0.090 ENSMUST00000093785.4
 Nat6
N-acetyltransferase 6
chr15_-_83251720 0.063 ENSMUST00000164614.1
ENSMUST00000049530.6
 A4galt

alpha 1,4-galactosyltransferase

chr4_-_156234777 0.006 ENSMUST00000105569.3
 Klhl17
kelch-like 17

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 5.2 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.4 1.6 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.3 1.6 GO:2000574 regulation of microtubule motor activity(GO:2000574)
0.2 0.9 GO:0010985 negative regulation of lipoprotein particle clearance(GO:0010985)
0.2 1.9 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.2 1.6 GO:0014832 urinary bladder smooth muscle contraction(GO:0014832)
0.2 0.2 GO:0042713 sperm ejaculation(GO:0042713)
0.2 1.0 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 0.8 GO:0060406 positive regulation of penile erection(GO:0060406)
0.1 1.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 0.5 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 3.4 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.1 1.1 GO:0015693 magnesium ion transport(GO:0015693)
0.1 1.0 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.1 0.6 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.1 0.4 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0035106 operant conditioning(GO:0035106)
0.0 0.1 GO:0010752 signal complex assembly(GO:0007172) regulation of cGMP-mediated signaling(GO:0010752)
0.0 1.3 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 1.4 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0098543 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0 1.4 GO:1904893 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 1.5 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.0 0.6 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.4 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.1 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.4 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 5.2 GO:0051233 spindle midzone(GO:0051233)
0.1 1.6 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.1 3.4 GO:0030673 axolemma(GO:0030673)
0.1 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.4 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 2.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.6 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.8 GO:0045171 intercellular bridge(GO:0045171)
0.0 1.0 GO:0005811 lipid particle(GO:0005811)
0.0 0.7 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.6 GO:0000776 kinetochore(GO:0000776)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.3 1.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.3 0.9 GO:0048019 receptor antagonist activity(GO:0048019)
0.3 0.8 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.3 1.6 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381) mercury ion binding(GO:0045340)
0.2 1.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 5.2 GO:0043274 phospholipase binding(GO:0043274)
0.1 2.3 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 1.8 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.1 0.5 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.1 1.0 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 3.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 2.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 1.6 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.4 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.1 1.3 GO:0015026 coreceptor activity(GO:0015026)
0.1 1.1 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.6 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 1.1 GO:0034945 dihydrolipoamide branched chain acyltransferase activity(GO:0004147) palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity(GO:0008951) serine O-acyltransferase activity(GO:0016412) O-succinyltransferase activity(GO:0016750) sinapoyltransferase activity(GO:0016752) O-sinapoyltransferase activity(GO:0016753) peptidyl-lysine N6-myristoyltransferase activity(GO:0018030) peptidyl-lysine N6-palmitoyltransferase activity(GO:0018031) benzoyl acetate-CoA thiolase activity(GO:0018711) 3-hydroxybutyryl-CoA thiolase activity(GO:0018712) 3-ketopimelyl-CoA thiolase activity(GO:0018713) N-palmitoyltransferase activity(GO:0019105) acyl-CoA N-acyltransferase activity(GO:0019186) protein-cysteine S-myristoyltransferase activity(GO:0019705) glucosaminyl-phosphotidylinositol O-acyltransferase activity(GO:0032216) ergosterol O-acyltransferase activity(GO:0034737) lanosterol O-acyltransferase activity(GO:0034738) naphthyl-2-oxomethyl-succinyl-CoA succinyl transferase activity(GO:0034848) 2,4,4-trimethyl-3-oxopentanoyl-CoA 2-C-propanoyl transferase activity(GO:0034851) 2-methylhexanoyl-CoA C-acetyltransferase activity(GO:0034915) butyryl-CoA 2-C-propionyltransferase activity(GO:0034919) 2,6-dimethyl-5-methylene-3-oxo-heptanoyl-CoA C-acetyltransferase activity(GO:0034945) L-2-aminoadipate N-acetyltransferase activity(GO:0043741) keto acid formate lyase activity(GO:0043806) azetidine-2-carboxylic acid acetyltransferase activity(GO:0046941) peptidyl-lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0052858) acetyl-CoA:L-lysine N6-acetyltransferase(GO:0090595)
0.0 1.0 GO:0045502 dynein binding(GO:0045502)
0.0 1.4 GO:0030276 clathrin binding(GO:0030276)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 1.4 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)