Motif ID: Gcm2

Z-value: 2.491


Transcription factors associated with Gcm2:

Gene SymbolEntrez IDGene Name
Gcm2 ENSMUSG00000021362.6 Gcm2



Activity profile for motif Gcm2.

activity profile for motif Gcm2


Sorted Z-values histogram for motif Gcm2

Sorted Z-values for motif Gcm2



Network of associatons between targets according to the STRING database.



First level regulatory network of Gcm2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_6065737 82.078 ENSMUST00000002817.5
ENSMUST00000109813.2
ENSMUST00000090443.3
 Camk2b


calcium/calmodulin-dependent protein kinase II, beta


chr11_-_6065538 49.597 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr12_-_79007276 32.399 ENSMUST00000056660.6
ENSMUST00000174721.1
 Tmem229b

transmembrane protein 229B

chr15_-_66831625 28.529 ENSMUST00000164163.1
 Sla
src-like adaptor
chrX_-_73880831 22.004 ENSMUST00000102871.3
 L1cam
L1 cell adhesion molecule
chr9_+_112234257 19.688 ENSMUST00000149308.3
ENSMUST00000144424.2
ENSMUST00000139552.2
 2900079G21Rik


RIKEN cDNA 2900079G21 gene


chr2_+_82053222 19.487 ENSMUST00000047527.7
 Zfp804a
zinc finger protein 804A
chr7_+_121392266 18.491 ENSMUST00000084628.3
 Hs3st2
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr5_-_37717122 17.659 ENSMUST00000094836.4
 Stk32b
serine/threonine kinase 32B
chr15_+_25414175 17.604 ENSMUST00000069992.5
 Gm5468
predicted gene 5468
chr11_+_98348404 17.556 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr4_-_138396438 17.267 ENSMUST00000105032.2
 Fam43b
family with sequence similarity 43, member B
chr3_+_96596628 15.396 ENSMUST00000058943.7
 Ankrd34a
ankyrin repeat domain 34A
chr4_+_13743424 15.239 ENSMUST00000006761.3
 Runx1t1
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr13_-_14523178 14.601 ENSMUST00000110516.2
 Hecw1
HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1
chr2_-_32353247 14.578 ENSMUST00000078352.5
ENSMUST00000113352.2
ENSMUST00000113365.1
 Dnm1


dynamin 1


chr11_-_116654245 14.157 ENSMUST00000021166.5
 Cygb
cytoglobin
chr9_+_57940104 13.804 ENSMUST00000043059.7
 Sema7a
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr5_+_110544326 13.260 ENSMUST00000040001.7
 Galnt9
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 9
chr2_+_90885860 12.675 ENSMUST00000111466.2
 C1qtnf4
C1q and tumor necrosis factor related protein 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 406 entries
Log-likelihood per target Total log-likelihoodTermDescription
43.9 131.7 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
3.2 25.6 GO:1903423 positive regulation of synaptic vesicle recycling(GO:1903423)
2.4 24.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.7 22.3 GO:0060074 synapse maturation(GO:0060074)
0.7 19.4 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.6 18.6 GO:0060749 mammary gland alveolus development(GO:0060749) mammary gland lobule development(GO:0061377)
0.2 18.0 GO:1903214 regulation of protein targeting to mitochondrion(GO:1903214)
5.9 17.6 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.8 17.6 GO:0010996 response to auditory stimulus(GO:0010996)
0.5 17.6 GO:0034605 cellular response to heat(GO:0034605)
0.3 15.9 GO:0001881 receptor recycling(GO:0001881)
2.8 14.2 GO:0015671 oxygen transport(GO:0015671)
1.5 13.8 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.4 13.5 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.2 12.6 GO:0051965 positive regulation of synapse assembly(GO:0051965)
1.8 12.4 GO:0035902 response to immobilization stress(GO:0035902)
1.2 12.3 GO:1900112 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.1 11.9 GO:0000209 protein polyubiquitination(GO:0000209)
0.7 11.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.4 11.4 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 185 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.0 126.9 GO:0051233 spindle midzone(GO:0051233)
0.8 36.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 28.7 GO:0005794 Golgi apparatus(GO:0005794)
0.1 26.5 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.6 23.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
1.3 20.1 GO:0043196 varicosity(GO:0043196)
0.3 19.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.1 18.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.0 17.1 GO:0043025 neuronal cell body(GO:0043025)
0.1 16.3 GO:0045211 postsynaptic membrane(GO:0045211)
0.2 14.2 GO:0031225 anchored component of membrane(GO:0031225)
0.1 12.2 GO:0043679 axon terminus(GO:0043679)
2.3 11.7 GO:0030314 junctional membrane complex(GO:0030314)
1.4 11.5 GO:0097433 dense body(GO:0097433)
0.0 11.5 GO:0005887 integral component of plasma membrane(GO:0005887)
0.3 11.2 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
1.0 11.0 GO:0043083 synaptic cleft(GO:0043083)
0.4 10.7 GO:0005868 cytoplasmic dynein complex(GO:0005868)
1.0 10.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.9 10.3 GO:0005677 chromatin silencing complex(GO:0005677)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 278 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.6 135.5 GO:0043274 phospholipase binding(GO:0043274)
0.9 29.1 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
3.1 25.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
5.5 22.0 GO:0033691 sialic acid binding(GO:0033691)
0.1 19.0 GO:0005516 calmodulin binding(GO:0005516)
5.9 17.6 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.5 16.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.6 15.5 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 14.9 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
3.5 14.2 GO:0004096 catalase activity(GO:0004096)
0.5 14.1 GO:0030215 semaphorin receptor binding(GO:0030215)
2.0 14.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
1.2 13.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 12.8 GO:0008289 lipid binding(GO:0008289)
0.2 12.6 GO:0035254 glutamate receptor binding(GO:0035254)
0.2 12.4 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 12.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.2 11.6 GO:0004376 glycolipid mannosyltransferase activity(GO:0004376)
2.3 11.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
3.8 11.3 GO:0004936 alpha-adrenergic receptor activity(GO:0004936) epinephrine binding(GO:0051379)