Motif ID: Gfi1_Gfi1b

Z-value: 1.491

Transcription factors associated with Gfi1_Gfi1b:

Gene SymbolEntrez IDGene Name
Gfi1 ENSMUSG00000029275.11 Gfi1
Gfi1b ENSMUSG00000026815.8 Gfi1b



Activity profile for motif Gfi1_Gfi1b.

activity profile for motif Gfi1_Gfi1b


Sorted Z-values histogram for motif Gfi1_Gfi1b

Sorted Z-values for motif Gfi1_Gfi1b



Network of associatons between targets according to the STRING database.



First level regulatory network of Gfi1_Gfi1b

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 31.290 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr16_-_26989974 20.008 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr7_+_62376979 11.497 ENSMUST00000080403.5
 Magel2
melanoma antigen, family L, 2
chr11_-_84525514 9.638 ENSMUST00000018842.7
 Lhx1
LIM homeobox protein 1
chr9_+_3000922 9.535 ENSMUST00000151376.2
 Gm10722
predicted gene 10722
chr9_+_3005125 9.505 ENSMUST00000179881.1
 Gm11168
predicted gene 11168
chr9_+_3013140 8.327 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr9_+_3034599 8.116 ENSMUST00000178641.1
 Gm17535
predicted gene, 17535
chr13_-_71963713 8.003 ENSMUST00000077337.8
 Irx1
Iroquois related homeobox 1 (Drosophila)
chr9_+_3015654 7.859 ENSMUST00000099050.3
 Gm10720
predicted gene 10720
chr9_+_3027439 7.723 ENSMUST00000177875.1
ENSMUST00000179982.1
 Gm10717

predicted gene 10717

chr9_+_3025417 7.345 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr9_+_3023547 7.228 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr13_+_35659856 7.129 ENSMUST00000075220.6
 Cdyl
chromodomain protein, Y chromosome-like
chr9_+_3017408 7.116 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr3_-_154330543 6.758 ENSMUST00000184966.1
ENSMUST00000177846.2
 Lhx8

LIM homeobox protein 8

chr11_+_84525669 6.459 ENSMUST00000126072.1
ENSMUST00000128121.1
 1500016L03Rik

RIKEN cDNA 1500016L03 gene

chr11_+_84525647 6.409 ENSMUST00000134800.1
 1500016L03Rik
RIKEN cDNA 1500016L03 gene
chr7_-_62464505 6.266 ENSMUST00000094339.2
 Peg12
paternally expressed 12
chr8_+_106935720 6.033 ENSMUST00000047425.3
 Sntb2
syntrophin, basic 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 220 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.2 31.3 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.7 23.2 GO:0006270 DNA replication initiation(GO:0006270)
3.4 13.6 GO:2000768 positive regulation of epithelial cell differentiation involved in kidney development(GO:2000698) positive regulation of nephron tubule epithelial cell differentiation(GO:2000768)
0.6 11.6 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.4 10.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.2 8.6 GO:1902476 chloride transmembrane transport(GO:1902476)
2.6 7.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.8 7.3 GO:0002074 extraocular skeletal muscle development(GO:0002074) pulmonary myocardium development(GO:0003350) subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.1 7.2 GO:0021884 forebrain neuron development(GO:0021884)
0.7 7.1 GO:0097421 liver regeneration(GO:0097421)
0.2 6.5 GO:0000578 embryonic axis specification(GO:0000578)
0.7 5.9 GO:0048625 myoblast fate commitment(GO:0048625)
1.9 5.8 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.4 5.6 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 5.2 GO:0008360 regulation of cell shape(GO:0008360)
0.0 5.1 GO:0008033 tRNA processing(GO:0008033)
0.7 4.4 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.5 4.1 GO:0061436 establishment of skin barrier(GO:0061436)
0.2 4.1 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.3 4.0 GO:0071803 positive regulation of podosome assembly(GO:0071803)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 110 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 11.5 GO:0030904 retromer complex(GO:0030904)
0.1 11.3 GO:0000776 kinetochore(GO:0000776)
2.6 7.7 GO:0005588 collagen type V trimer(GO:0005588)
0.2 7.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
1.1 6.8 GO:0001674 female germ cell nucleus(GO:0001674)
0.7 5.9 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.1 5.0 GO:0034707 chloride channel complex(GO:0034707)
0.1 4.3 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.5 4.2 GO:0033269 internode region of axon(GO:0033269)
0.1 4.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.2 4.0 GO:0002102 podosome(GO:0002102)
0.0 4.0 GO:0016607 nuclear speck(GO:0016607)
0.0 4.0 GO:0005667 transcription factor complex(GO:0005667)
1.3 3.9 GO:0071914 prominosome(GO:0071914)
0.1 3.7 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 3.6 GO:0005876 spindle microtubule(GO:0005876)
0.0 3.0 GO:0043209 myelin sheath(GO:0043209)
0.1 2.9 GO:0005801 cis-Golgi network(GO:0005801)
0.2 2.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 2.8 GO:0045180 basal cortex(GO:0045180)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 156 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 47.6 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 30.1 GO:0043565 sequence-specific DNA binding(GO:0043565)
0.0 20.8 GO:0003682 chromatin binding(GO:0003682)
0.0 17.2 GO:0003779 actin binding(GO:0003779)
0.0 13.2 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.1 8.6 GO:0035064 methylated histone binding(GO:0035064)
0.2 7.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.2 7.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.1 6.0 GO:0051082 unfolded protein binding(GO:0051082)
0.3 5.9 GO:0045295 gamma-catenin binding(GO:0045295)
0.3 5.6 GO:0070410 co-SMAD binding(GO:0070410)
0.1 5.4 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
1.7 5.0 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.2 4.8 GO:0042805 actinin binding(GO:0042805)
0.1 4.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 4.7 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 4.5 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.3 4.5 GO:0035198 miRNA binding(GO:0035198)
0.4 4.3 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.1 4.1 GO:0031490 chromatin DNA binding(GO:0031490)