Motif ID: Gli3_Zic1

Z-value: 1.525

Transcription factors associated with Gli3_Zic1:

Gene SymbolEntrez IDGene Name
Gli3 ENSMUSG00000021318.9 Gli3
Zic1 ENSMUSG00000032368.8 Zic1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gli3mm10_v2_chr13_+_15463837_15463980-0.606.5e-07Click!
Zic1mm10_v2_chr9_-_91365756_91365774-0.229.0e-02Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gli3_Zic1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr16_+_91269759 17.881 ENSMUST00000056882.5
Olig1
oligodendrocyte transcription factor 1
chr9_+_50752758 14.540 ENSMUST00000034562.7
Cryab
crystallin, alpha B
chr4_-_148130678 11.424 ENSMUST00000030862.4
Draxin
dorsal inhibitory axon guidance protein
chr10_-_127341583 9.884 ENSMUST00000026474.3
Gli1
GLI-Kruppel family member GLI1
chr6_-_101377897 9.729 ENSMUST00000075994.6
Pdzrn3
PDZ domain containing RING finger 3
chr8_-_105966038 9.122 ENSMUST00000116429.2
ENSMUST00000034370.9
Slc12a4

solute carrier family 12, member 4

chr2_-_29253001 8.916 ENSMUST00000071201.4
Ntng2
netrin G2
chr6_-_101377342 8.878 ENSMUST00000151175.1
Pdzrn3
PDZ domain containing RING finger 3
chr7_-_100656953 8.734 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
Plekhb1


pleckstrin homology domain containing, family B (evectins) member 1


chr8_+_70501116 8.699 ENSMUST00000127983.1
Crlf1
cytokine receptor-like factor 1
chrX_-_16911774 8.522 ENSMUST00000040134.7
Ndp
Norrie disease (pseudoglioma) (human)
chr4_-_68954351 7.693 ENSMUST00000030036.5
Brinp1
bone morphogenic protein/retinoic acid inducible neural specific 1
chr1_-_133801031 7.072 ENSMUST00000143567.1
Atp2b4
ATPase, Ca++ transporting, plasma membrane 4
chr4_+_124657646 6.959 ENSMUST00000053491.7
Pou3f1
POU domain, class 3, transcription factor 1
chr9_-_54661666 6.830 ENSMUST00000128624.1
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr9_-_54661870 6.779 ENSMUST00000034822.5
Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr18_-_38601268 6.708 ENSMUST00000025295.6
Spry4
sprouty homolog 4 (Drosophila)
chr16_-_28445227 6.656 ENSMUST00000100024.1
Fgf12
fibroblast growth factor 12
chr6_+_86195214 6.636 ENSMUST00000032066.9
Tgfa
transforming growth factor alpha
chr7_-_19698383 6.402 ENSMUST00000173739.1
Apoe
apolipoprotein E
chrX_+_101299143 6.273 ENSMUST00000118111.1
ENSMUST00000130555.1
ENSMUST00000151528.1
Nlgn3


neuroligin 3


chr6_-_125494754 6.265 ENSMUST00000032492.8
Cd9
CD9 antigen
chr6_-_115251839 5.882 ENSMUST00000032462.6
Timp4
tissue inhibitor of metalloproteinase 4
chrX_+_101299207 5.794 ENSMUST00000065858.2
Nlgn3
neuroligin 3
chr14_-_55560340 5.772 ENSMUST00000066106.3
A730061H03Rik
RIKEN cDNA A730061H03 gene
chr2_+_35282380 5.578 ENSMUST00000028239.6
Gsn
gelsolin
chr15_-_95528228 5.575 ENSMUST00000075275.2
Nell2
NEL-like 2
chr6_-_113531575 5.504 ENSMUST00000032425.5
Emc3
ER membrane protein complex subunit 3
chr18_+_86394952 5.423 ENSMUST00000058829.2
Neto1
neuropilin (NRP) and tolloid (TLL)-like 1
chr7_+_99268338 5.392 ENSMUST00000107100.2
Map6
microtubule-associated protein 6
chr3_+_68494208 5.168 ENSMUST00000182719.1
Schip1
schwannomin interacting protein 1
chr8_+_76902277 5.085 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
Nr3c2


nuclear receptor subfamily 3, group C, member 2


chr7_+_24370255 4.843 ENSMUST00000171904.1
Kcnn4
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr1_-_135167606 4.807 ENSMUST00000027682.8
Gpr37l1
G protein-coupled receptor 37-like 1
chr10_-_64090265 4.789 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr1_-_134234492 4.675 ENSMUST00000169927.1
Adora1
adenosine A1 receptor
chr11_+_101246405 4.502 ENSMUST00000122006.1
ENSMUST00000151830.1
Ramp2

receptor (calcitonin) activity modifying protein 2

chr4_+_144893077 4.425 ENSMUST00000154208.1
Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr11_-_42000284 4.356 ENSMUST00000109292.2
ENSMUST00000109290.1
Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr1_-_134235420 4.343 ENSMUST00000038191.6
ENSMUST00000086465.4
Adora1

adenosine A1 receptor

chr15_-_78718113 4.330 ENSMUST00000088592.4
Elfn2
leucine rich repeat and fibronectin type III, extracellular 2
chr14_-_30353468 4.259 ENSMUST00000112249.1
Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr10_-_64090241 4.213 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr12_+_73997749 4.150 ENSMUST00000110451.2
Syt16
synaptotagmin XVI
chr11_+_69765970 4.132 ENSMUST00000108642.1
ENSMUST00000156932.1
Zbtb4

zinc finger and BTB domain containing 4

chr1_-_69108039 4.095 ENSMUST00000121473.1
Erbb4
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr14_+_55560480 4.092 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
Dcaf11


DDB1 and CUL4 associated factor 11


chr2_-_36104060 4.085 ENSMUST00000112961.3
ENSMUST00000112966.3
Lhx6

LIM homeobox protein 6

chr13_-_54611274 4.067 ENSMUST00000049575.7
Cltb
clathrin, light polypeptide (Lcb)
chr17_+_37050631 3.983 ENSMUST00000172792.1
ENSMUST00000174347.1
Gabbr1

gamma-aminobutyric acid (GABA) B receptor, 1

chr3_+_105452326 3.959 ENSMUST00000098761.3
Kcnd3
potassium voltage-gated channel, Shal-related family, member 3
chr8_+_54954728 3.945 ENSMUST00000033915.7
Gpm6a
glycoprotein m6a
chr7_-_142657466 3.945 ENSMUST00000097936.2
ENSMUST00000000033.5
Igf2

insulin-like growth factor 2

chr6_-_119330723 3.929 ENSMUST00000068351.7
Lrtm2
leucine-rich repeats and transmembrane domains 2
chr5_+_71699918 3.913 ENSMUST00000031122.7
Gabrb1
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr6_+_110645572 3.904 ENSMUST00000071076.6
ENSMUST00000172951.1
Grm7

glutamate receptor, metabotropic 7

chr4_+_133011506 3.877 ENSMUST00000105915.1
ENSMUST00000105916.1
Ahdc1

AT hook, DNA binding motif, containing 1

chr4_+_48045144 3.792 ENSMUST00000030025.3
Nr4a3
nuclear receptor subfamily 4, group A, member 3
chr11_-_42000532 3.790 ENSMUST00000070735.3
Gabrg2
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr6_+_17463749 3.756 ENSMUST00000115443.1
Met
met proto-oncogene
chr17_-_24209377 3.654 ENSMUST00000024931.4
Ntn3
netrin 3
chr8_-_105637403 3.594 ENSMUST00000182046.1
Gm5914
predicted gene 5914
chr13_-_54611332 3.518 ENSMUST00000091609.4
Cltb
clathrin, light polypeptide (Lcb)
chr15_-_99820072 3.517 ENSMUST00000109024.2
Lima1
LIM domain and actin binding 1
chr2_+_102658640 3.493 ENSMUST00000080210.3
Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr7_+_99535439 3.461 ENSMUST00000098266.2
ENSMUST00000179755.1
Arrb1

arrestin, beta 1

chr2_+_70562007 3.399 ENSMUST00000094934.4
Gad1
glutamate decarboxylase 1
chr7_-_79131018 3.379 ENSMUST00000032827.7
Hapln3
hyaluronan and proteoglycan link protein 3
chrX_-_7574120 3.378 ENSMUST00000045924.7
ENSMUST00000115742.2
ENSMUST00000150787.1
Ppp1r3f


protein phosphatase 1, regulatory (inhibitor) subunit 3F


chr4_+_123233556 3.358 ENSMUST00000040821.4
Heyl
hairy/enhancer-of-split related with YRPW motif-like
chr15_-_56694525 3.353 ENSMUST00000050544.7
Has2
hyaluronan synthase 2
chr9_-_58158498 3.260 ENSMUST00000168864.2
Islr
immunoglobulin superfamily containing leucine-rich repeat
chr16_+_43503607 3.186 ENSMUST00000126100.1
ENSMUST00000123047.1
ENSMUST00000156981.1
Zbtb20


zinc finger and BTB domain containing 20


chr9_-_56418023 3.142 ENSMUST00000061552.8
C230081A13Rik
RIKEN cDNA C230081A13 gene
chr7_+_128246812 3.109 ENSMUST00000164710.1
ENSMUST00000070656.5
Tgfb1i1

transforming growth factor beta 1 induced transcript 1

chr5_+_26817357 3.103 ENSMUST00000071500.6
Dpp6
dipeptidylpeptidase 6
chr7_-_84605819 3.102 ENSMUST00000032865.9
Fah
fumarylacetoacetate hydrolase
chr14_+_55560904 3.082 ENSMUST00000072530.4
ENSMUST00000128490.1
Dcaf11

DDB1 and CUL4 associated factor 11

chr7_+_57591147 3.081 ENSMUST00000039697.7
Gabrb3
gamma-aminobutyric acid (GABA) A receptor, subunit beta 3
chr11_+_100415722 3.057 ENSMUST00000107400.2
Fkbp10
FK506 binding protein 10
chrX_+_163908982 3.047 ENSMUST00000069041.8
Ap1s2
adaptor-related protein complex 1, sigma 2 subunit
chr11_-_70229677 3.035 ENSMUST00000153449.1
ENSMUST00000000326.5
Bcl6b

B cell CLL/lymphoma 6, member B

chr13_+_54949388 2.982 ENSMUST00000026994.7
ENSMUST00000109994.2
Unc5a

unc-5 homolog A (C. elegans)

chr15_-_100584075 2.981 ENSMUST00000184908.1
POU6F1
POU domain, class 6, transcription factor 1 (Pou6f1), mRNA
chr7_+_5057161 2.925 ENSMUST00000045543.5
Ccdc106
coiled-coil domain containing 106
chr11_-_60352869 2.918 ENSMUST00000095254.5
ENSMUST00000102683.4
ENSMUST00000093048.6
ENSMUST00000093046.6
ENSMUST00000064019.8
ENSMUST00000102682.4
Tom1l2





target of myb1-like 2 (chicken)





chr3_+_45378396 2.912 ENSMUST00000166126.1
ENSMUST00000170695.1
ENSMUST00000171554.1
Pcdh10


protocadherin 10


chr1_-_22805994 2.899 ENSMUST00000097808.4
Rims1
regulating synaptic membrane exocytosis 1
chr1_-_180483410 2.828 ENSMUST00000136521.1
ENSMUST00000179826.1
6330403A02Rik

RIKEN cDNA 6330403A02 gene

chr4_-_136956784 2.825 ENSMUST00000030420.8
Epha8
Eph receptor A8
chr2_-_144527341 2.784 ENSMUST00000163701.1
ENSMUST00000081982.5
Dzank1

double zinc ribbon and ankyrin repeat domains 1

chr11_+_70647258 2.779 ENSMUST00000037534.7
Rnf167
ring finger protein 167
chr8_-_105637350 2.771 ENSMUST00000182863.1
Gm5914
predicted gene 5914
chr19_+_5740885 2.760 ENSMUST00000081496.5
Ltbp3
latent transforming growth factor beta binding protein 3
chr15_-_95528702 2.752 ENSMUST00000166170.1
Nell2
NEL-like 2
chr7_+_128246953 2.742 ENSMUST00000167965.1
Tgfb1i1
transforming growth factor beta 1 induced transcript 1
chr7_+_5056856 2.742 ENSMUST00000131368.1
ENSMUST00000123956.1
Ccdc106

coiled-coil domain containing 106

chr8_-_85840877 2.729 ENSMUST00000034140.7
Itfg1
integrin alpha FG-GAP repeat containing 1
chr11_+_101246960 2.682 ENSMUST00000107282.3
Ramp2
receptor (calcitonin) activity modifying protein 2
chr13_-_117025505 2.656 ENSMUST00000022239.6
Parp8
poly (ADP-ribose) polymerase family, member 8
chr19_-_4698315 2.617 ENSMUST00000096325.3
Gm960
predicted gene 960
chr12_+_4234023 2.605 ENSMUST00000179139.1
Ptrhd1
peptidyl-tRNA hydrolase domain containing 1
chr9_+_86695542 2.521 ENSMUST00000150367.2
A330041J22Rik
RIKEN cDNA A330041J22 gene
chr6_-_118780324 2.497 ENSMUST00000112793.3
ENSMUST00000075591.6
ENSMUST00000078320.7
ENSMUST00000112790.2
Cacna1c



calcium channel, voltage-dependent, L type, alpha 1C subunit



chr11_-_116654245 2.494 ENSMUST00000021166.5
Cygb
cytoglobin
chr9_+_100643605 2.468 ENSMUST00000041418.6
Stag1
stromal antigen 1
chr2_-_125723387 2.467 ENSMUST00000042246.7
Shc4
SHC (Src homology 2 domain containing) family, member 4
chr9_+_100643448 2.462 ENSMUST00000146312.1
ENSMUST00000129269.1
Stag1

stromal antigen 1

chr2_+_158667119 2.439 ENSMUST00000045503.4
Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr17_+_37045980 2.434 ENSMUST00000174456.1
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr5_-_34187670 2.418 ENSMUST00000042701.6
ENSMUST00000119171.1
Mxd4

Max dimerization protein 4

chr11_+_69095217 2.408 ENSMUST00000101004.2
Per1
period circadian clock 1
chr5_+_3343893 2.402 ENSMUST00000165117.1
Cdk6
cyclin-dependent kinase 6
chr9_+_100643755 2.365 ENSMUST00000133388.1
Stag1
stromal antigen 1
chr1_-_56972437 2.349 ENSMUST00000042857.7
Satb2
special AT-rich sequence binding protein 2
chr3_+_27984145 2.325 ENSMUST00000067757.4
Pld1
phospholipase D1
chr7_+_5056706 2.317 ENSMUST00000144802.1
Ccdc106
coiled-coil domain containing 106
chr14_+_84443553 2.315 ENSMUST00000071370.5
Pcdh17
protocadherin 17
chr1_-_153900198 2.295 ENSMUST00000123490.1
5830403L16Rik
RIKEN cDNA 5830403L16 gene
chr1_-_125912160 2.293 ENSMUST00000159417.1
Lypd1
Ly6/Plaur domain containing 1
chrX_+_101383726 2.284 ENSMUST00000119190.1
Gjb1
gap junction protein, beta 1
chr14_+_55561060 2.283 ENSMUST00000117701.1
Dcaf11
DDB1 and CUL4 associated factor 11
chr3_+_28263205 2.282 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr13_+_54575020 2.264 ENSMUST00000156024.1
Arl10
ADP-ribosylation factor-like 10
chr1_+_153900572 2.121 ENSMUST00000139476.1
Glul
glutamate-ammonia ligase (glutamine synthetase)
chr17_+_37045963 2.099 ENSMUST00000025338.9
Gabbr1
gamma-aminobutyric acid (GABA) B receptor, 1
chr18_+_5593566 2.093 ENSMUST00000160910.1
Zeb1
zinc finger E-box binding homeobox 1
chr18_-_78142119 2.062 ENSMUST00000160639.1
Slc14a1
solute carrier family 14 (urea transporter), member 1
chr10_+_40349265 2.054 ENSMUST00000044672.4
ENSMUST00000095743.2
Cdk19

cyclin-dependent kinase 19

chr16_+_20733104 2.046 ENSMUST00000115423.1
ENSMUST00000007171.6
Chrd

chordin

chr7_-_111779963 2.045 ENSMUST00000049430.8
ENSMUST00000106663.1
Galnt18

UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 18

chr6_-_28830345 2.040 ENSMUST00000171353.1
Lrrc4
leucine rich repeat containing 4
chr7_+_25267669 2.017 ENSMUST00000169266.1
Cic
capicua homolog (Drosophila)
chr5_-_75044562 1.987 ENSMUST00000075452.5
Chic2
cysteine-rich hydrophobic domain 2
chr16_+_17561885 1.986 ENSMUST00000171002.1
ENSMUST00000023441.4
P2rx6

purinergic receptor P2X, ligand-gated ion channel, 6

chr2_-_77170592 1.977 ENSMUST00000164114.2
ENSMUST00000049544.7
Ccdc141

coiled-coil domain containing 141

chr8_-_69887687 1.936 ENSMUST00000057831.7
Cilp2
cartilage intermediate layer protein 2
chr12_+_95692212 1.933 ENSMUST00000057324.3
Flrt2
fibronectin leucine rich transmembrane protein 2
chr10_+_40629987 1.921 ENSMUST00000019977.7
Ddo
D-aspartate oxidase
chr6_+_17463927 1.895 ENSMUST00000115442.1
Met
met proto-oncogene
chr11_-_100939540 1.880 ENSMUST00000127638.1
Stat3
signal transducer and activator of transcription 3
chr18_+_52767994 1.872 ENSMUST00000025413.7
ENSMUST00000163742.2
ENSMUST00000178011.1
Sncaip


synuclein, alpha interacting protein (synphilin)


chr18_-_43373248 1.872 ENSMUST00000118043.1
Dpysl3
dihydropyrimidinase-like 3
chr4_-_151108244 1.837 ENSMUST00000131948.1
Camta1
calmodulin binding transcription activator 1
chr11_+_87760533 1.832 ENSMUST00000039627.5
ENSMUST00000100644.3
Bzrap1

benzodiazepine receptor associated protein 1

chr1_+_195017399 1.830 ENSMUST00000181273.1
A330023F24Rik
RIKEN cDNA A330023F24 gene
chr9_-_108190352 1.829 ENSMUST00000035208.7
Bsn
bassoon
chr16_-_44016387 1.819 ENSMUST00000036174.3
Gramd1c
GRAM domain containing 1C
chrX_+_163909132 1.819 ENSMUST00000033734.7
ENSMUST00000112294.2
Ap1s2

adaptor-related protein complex 1, sigma 2 subunit

chr13_+_54575008 1.795 ENSMUST00000026988.4
Arl10
ADP-ribosylation factor-like 10
chr19_-_32388462 1.793 ENSMUST00000099514.3
Sgms1
sphingomyelin synthase 1
chr4_-_120287349 1.783 ENSMUST00000102656.3
Foxo6
forkhead box O6
chr11_-_100939457 1.776 ENSMUST00000138438.1
Stat3
signal transducer and activator of transcription 3
chr1_-_165460430 1.746 ENSMUST00000027856.7
Dcaf6
DDB1 and CUL4 associated factor 6
chrX_-_150812715 1.740 ENSMUST00000112697.3
Maged2
melanoma antigen, family D, 2
chr7_+_35119285 1.737 ENSMUST00000042985.9
Cebpa
CCAAT/enhancer binding protein (C/EBP), alpha
chr5_+_143370092 1.736 ENSMUST00000120825.1
Grid2ip
glutamate receptor, ionotropic, delta 2 (Grid2) interacting protein 1
chrX_+_159697308 1.701 ENSMUST00000123433.1
Sh3kbp1
SH3-domain kinase binding protein 1
chr1_+_131827977 1.686 ENSMUST00000086559.6
Slc41a1
solute carrier family 41, member 1
chr3_+_31149934 1.685 ENSMUST00000046174.6
Cldn11
claudin 11
chr11_-_100939357 1.681 ENSMUST00000092671.5
ENSMUST00000103114.1
Stat3

signal transducer and activator of transcription 3

chr6_+_125494419 1.681 ENSMUST00000181266.1
Gm26728
predicted gene, 26728
chr16_+_23107413 1.680 ENSMUST00000023599.6
ENSMUST00000168891.1
Eif4a2

eukaryotic translation initiation factor 4A2

chr7_-_80401707 1.677 ENSMUST00000120753.1
Furin
furin (paired basic amino acid cleaving enzyme)
chr9_-_79793378 1.659 ENSMUST00000034878.5
Tmem30a
transmembrane protein 30A
chr17_-_68004075 1.646 ENSMUST00000024840.5
Arhgap28
Rho GTPase activating protein 28
chr10_+_127165118 1.618 ENSMUST00000006914.9
B4galnt1
beta-1,4-N-acetyl-galactosaminyl transferase 1
chr2_-_45110241 1.593 ENSMUST00000177302.1
Zeb2
zinc finger E-box binding homeobox 2
chr3_-_89245159 1.583 ENSMUST00000090924.6
Trim46
tripartite motif-containing 46
chr9_-_79793507 1.578 ENSMUST00000120690.1
Tmem30a
transmembrane protein 30A
chr14_+_45351473 1.576 ENSMUST00000111835.2
Styx
serine/threonine/tyrosine interaction protein
chrX_+_73064787 1.573 ENSMUST00000060418.6
Pnma3
paraneoplastic antigen MA3
chrX_+_155262443 1.567 ENSMUST00000026324.9
Acot9
acyl-CoA thioesterase 9
chr16_-_30550560 1.487 ENSMUST00000140402.1
Tmem44
transmembrane protein 44
chr2_-_160872985 1.476 ENSMUST00000109460.1
ENSMUST00000127201.1
Zhx3

zinc fingers and homeoboxes 3

chr15_+_99392882 1.465 ENSMUST00000023749.8
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr5_-_118244861 1.455 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
Rnft2



ring finger protein, transmembrane 2



chrX_+_10717451 1.455 ENSMUST00000156321.1
Mid1ip1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr16_-_91011308 1.446 ENSMUST00000121759.1
Synj1
synaptojanin 1
chr11_+_78245743 1.443 ENSMUST00000002133.8
Sdf2
stromal cell derived factor 2
chr6_-_35539765 1.440 ENSMUST00000031866.5
Mtpn
myotrophin
chrX_+_74329058 1.424 ENSMUST00000004326.3
Plxna3
plexin A3
chr6_+_17463826 1.416 ENSMUST00000140070.1
Met
met proto-oncogene
chr2_-_45110336 1.412 ENSMUST00000028229.6
ENSMUST00000152232.1
Zeb2

zinc finger E-box binding homeobox 2

chr14_+_70530819 1.406 ENSMUST00000047331.6
Lgi3
leucine-rich repeat LGI family, member 3
chr11_-_42182163 1.403 ENSMUST00000153147.1
Gabra1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr2_+_164879358 1.402 ENSMUST00000041643.3
Pcif1
PDX1 C-terminal inhibiting factor 1
chr2_-_168230353 1.396 ENSMUST00000154111.1
Dpm1
dolichol-phosphate (beta-D) mannosyltransferase 1
chr11_+_51289920 1.389 ENSMUST00000102765.2
Col23a1
collagen, type XXIII, alpha 1
chr11_+_4135233 1.386 ENSMUST00000124670.1
Rnf215
ring finger protein 215
chr7_-_99626936 1.383 ENSMUST00000178124.1
Gm4980
predicted gene 4980
chr1_+_167598384 1.378 ENSMUST00000015987.3
Rxrg
retinoid X receptor gamma
chr17_-_27204357 1.373 ENSMUST00000055117.7
Lemd2
LEM domain containing 2
chr12_-_70227622 1.371 ENSMUST00000071250.6
Pygl
liver glycogen phosphorylase
chrX_+_10717390 1.371 ENSMUST00000115524.1
ENSMUST00000008179.6
Mid1ip1

Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))

chr11_+_73018986 1.371 ENSMUST00000092937.6
Camkk1
calcium/calmodulin-dependent protein kinase kinase 1, alpha
chr6_-_85502980 1.359 ENSMUST00000159062.1
Fbxo41
F-box protein 41
chr5_+_30588078 1.340 ENSMUST00000066295.2
Kcnk3
potassium channel, subfamily K, member 3
chr2_-_39190687 1.329 ENSMUST00000142872.1
ENSMUST00000038874.5
Scai

suppressor of cancer cell invasion

chr11_+_60353324 1.325 ENSMUST00000070805.6
ENSMUST00000094140.2
ENSMUST00000108723.2
ENSMUST00000108722.4
Lrrc48



leucine rich repeat containing 48




Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 9.3 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
2.5 9.9 GO:0060032 notochord regression(GO:0060032)
2.4 14.5 GO:0007021 tubulin complex assembly(GO:0007021)
2.4 7.1 GO:0045763 regulation of arginine metabolic process(GO:0000821) negative regulation of cellular amino acid metabolic process(GO:0045763)
2.1 6.4 GO:2001139 negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139)
2.1 12.4 GO:0060024 rhythmic synaptic transmission(GO:0060024)
1.9 5.6 GO:1903903 striated muscle atrophy(GO:0014891) positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of establishment of T cell polarity(GO:1903903)
1.8 16.5 GO:0071420 cellular response to histamine(GO:0071420)
1.8 7.1 GO:1900623 regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
1.8 5.3 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
1.7 8.5 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
1.4 4.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
1.4 8.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
1.4 5.5 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
1.2 8.5 GO:0032811 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of epinephrine secretion(GO:0032811)
1.2 5.9 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
1.0 3.1 GO:0006558 L-phenylalanine metabolic process(GO:0006558) erythrose 4-phosphate/phosphoenolpyruvate family amino acid metabolic process(GO:1902221)
1.0 3.0 GO:0016191 synaptic vesicle uncoating(GO:0016191) regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
1.0 4.8 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.9 2.8 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.9 6.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.9 9.8 GO:0071635 negative regulation of transforming growth factor beta production(GO:0071635)
0.9 2.6 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.8 3.4 GO:2000823 regulation of androgen receptor activity(GO:2000823)
0.8 5.9 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.8 2.4 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.8 3.9 GO:0001661 conditioned taste aversion(GO:0001661)
0.8 8.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.8 0.8 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.8 9.0 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.7 2.9 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.7 7.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.7 2.1 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.7 4.8 GO:0021940 positive regulation of cerebellar granule cell precursor proliferation(GO:0021940)
0.7 4.1 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.7 8.0 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.7 6.6 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.6 7.7 GO:0042711 maternal behavior(GO:0042711)
0.6 1.9 GO:0006533 aspartate catabolic process(GO:0006533) D-amino acid catabolic process(GO:0019478)
0.6 2.5 GO:0086045 smooth muscle contraction involved in micturition(GO:0060083) membrane depolarization during AV node cell action potential(GO:0086045) membrane depolarization during atrial cardiac muscle cell action potential(GO:0098912)
0.6 2.4 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.6 2.4 GO:0097167 circadian regulation of translation(GO:0097167)
0.6 11.4 GO:0021516 dorsal spinal cord development(GO:0021516)
0.6 3.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.6 2.3 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.6 1.7 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.6 0.6 GO:0060681 branch elongation involved in ureteric bud branching(GO:0060681)
0.6 3.5 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393)
0.6 3.4 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.5 4.9 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.5 3.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.5 2.7 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) negative regulation of immunoglobulin secretion(GO:0051025) negative regulation of ribonuclease activity(GO:0060701) negative regulation of endoribonuclease activity(GO:0060702) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.5 1.6 GO:0045204 MAPK export from nucleus(GO:0045204)
0.5 3.0 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.5 2.5 GO:0015671 oxygen transport(GO:0015671)
0.5 1.9 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.5 1.4 GO:0070589 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554)
0.5 1.9 GO:0009957 epidermal cell fate specification(GO:0009957)
0.5 2.8 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.5 2.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.5 2.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.4 3.6 GO:0036506 maintenance of unfolded protein(GO:0036506) protein insertion into ER membrane(GO:0045048) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.4 4.0 GO:0071435 potassium ion export(GO:0071435)
0.4 1.6 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.4 6.6 GO:0001553 luteinization(GO:0001553)
0.4 18.6 GO:0007528 neuromuscular junction development(GO:0007528)
0.4 4.4 GO:0042572 retinol metabolic process(GO:0042572)
0.4 14.6 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.4 3.0 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.4 1.4 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.3 1.0 GO:1903722 regulation of centriole elongation(GO:1903722)
0.3 1.7 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.3 2.3 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.3 1.6 GO:0030259 lipid glycosylation(GO:0030259)
0.3 5.1 GO:0031958 corticosteroid receptor signaling pathway(GO:0031958)
0.3 0.3 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.3 0.9 GO:1902358 sulfate transmembrane transport(GO:1902358)
0.3 2.1 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.3 0.9 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.3 20.2 GO:0048663 neuron fate commitment(GO:0048663)
0.3 1.6 GO:0060872 semicircular canal morphogenesis(GO:0048752) semicircular canal development(GO:0060872)
0.3 2.8 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.3 1.8 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.3 2.3 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.2 1.7 GO:0000050 urea cycle(GO:0000050) urea metabolic process(GO:0019627) cellular response to lithium ion(GO:0071285)
0.2 0.5 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.2 1.0 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.2 1.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 1.4 GO:0021636 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637)
0.2 6.5 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.2 8.4 GO:2001258 negative regulation of cation channel activity(GO:2001258)
0.2 2.0 GO:0097119 postsynaptic density protein 95 clustering(GO:0097119)
0.2 1.4 GO:0036233 glycine import(GO:0036233)
0.2 1.1 GO:0061687 detoxification of inorganic compound(GO:0061687)
0.2 0.8 GO:0046487 glyoxylate metabolic process(GO:0046487)
0.2 5.4 GO:2000463 positive regulation of excitatory postsynaptic potential(GO:2000463)
0.2 1.3 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.2 2.2 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.2 0.4 GO:0003032 detection of oxygen(GO:0003032)
0.2 1.4 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 0.7 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.2 1.2 GO:0099625 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307) ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.2 1.0 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.2 0.3 GO:2001025 positive regulation of response to drug(GO:2001025)
0.2 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 1.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.4 GO:0021523 somatic motor neuron differentiation(GO:0021523)
0.1 1.0 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 0.9 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)
0.1 9.3 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.1 0.7 GO:0048597 post-embryonic camera-type eye morphogenesis(GO:0048597)
0.1 0.7 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.1 1.4 GO:0051601 exocyst localization(GO:0051601)
0.1 0.8 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.1 0.4 GO:1900275 negative regulation of phospholipase C activity(GO:1900275) regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900736)
0.1 5.4 GO:0032418 lysosome localization(GO:0032418)
0.1 2.3 GO:0035094 response to nicotine(GO:0035094)
0.1 2.8 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.1 0.3 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.6 GO:0051697 protein delipidation(GO:0051697)
0.1 0.4 GO:0019042 viral latency(GO:0019042)
0.1 1.7 GO:0007216 G-protein coupled glutamate receptor signaling pathway(GO:0007216)
0.1 0.6 GO:0043615 astrocyte cell migration(GO:0043615)
0.1 0.8 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.1 3.7 GO:0007520 myoblast fusion(GO:0007520)
0.1 0.7 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.1 1.3 GO:0048305 immunoglobulin secretion(GO:0048305)
0.1 3.1 GO:0090004 positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.1 5.2 GO:0030216 keratinocyte differentiation(GO:0030216)
0.1 0.2 GO:0010726 positive regulation of hydrogen peroxide metabolic process(GO:0010726)
0.1 0.7 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 6.4 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.1 0.9 GO:0097011 cellular response to granulocyte macrophage colony-stimulating factor stimulus(GO:0097011) response to granulocyte macrophage colony-stimulating factor(GO:0097012)
0.1 1.4 GO:0070207 protein homotrimerization(GO:0070207)
0.1 0.3 GO:0035864 response to potassium ion(GO:0035864) cellular response to potassium ion(GO:0035865) axonogenesis involved in innervation(GO:0060385)
0.1 2.0 GO:0033198 response to ATP(GO:0033198)
0.1 1.5 GO:0090083 regulation of inclusion body assembly(GO:0090083)
0.1 1.4 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.1 1.3 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 5.2 GO:0043407 negative regulation of MAP kinase activity(GO:0043407)
0.1 3.5 GO:0031529 ruffle organization(GO:0031529)
0.1 0.2 GO:0003256 regulation of transcription from RNA polymerase II promoter involved in myocardial precursor cell differentiation(GO:0003256) atrioventricular canal development(GO:0036302)
0.1 0.9 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)
0.1 1.5 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 1.6 GO:0046329 negative regulation of JNK cascade(GO:0046329)
0.1 0.9 GO:0060384 innervation(GO:0060384)
0.1 1.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.2 GO:0045950 telomeric loop formation(GO:0031627) negative regulation of mitotic recombination(GO:0045950) negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 0.8 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.1 2.3 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.1 1.4 GO:0070266 necroptotic process(GO:0070266)
0.1 0.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.1 1.8 GO:0035418 protein localization to synapse(GO:0035418)
0.1 0.2 GO:0070124 mitochondrial translational initiation(GO:0070124)
0.1 2.9 GO:0045839 negative regulation of mitotic nuclear division(GO:0045839)
0.1 3.9 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.1 2.5 GO:0006893 Golgi to plasma membrane transport(GO:0006893)
0.1 0.7 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.4 GO:0044539 long-chain fatty acid import(GO:0044539)
0.1 2.0 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.1 0.3 GO:0015074 DNA integration(GO:0015074)
0.1 2.6 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.1 7.2 GO:0006813 potassium ion transport(GO:0006813)
0.1 0.3 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 1.8 GO:0072661 protein targeting to plasma membrane(GO:0072661)
0.0 2.1 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.5 GO:0033169 histone H3-K9 demethylation(GO:0033169) regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.4 GO:0070914 UV-damage excision repair(GO:0070914)
0.0 1.0 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.5 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 1.1 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.4 GO:0006828 manganese ion transport(GO:0006828)
0.0 0.2 GO:0010919 regulation of inositol phosphate biosynthetic process(GO:0010919) positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.3 GO:0042407 cristae formation(GO:0042407)
0.0 1.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.1 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.1 GO:0006703 estrogen biosynthetic process(GO:0006703)
0.0 0.1 GO:0006361 transcription initiation from RNA polymerase I promoter(GO:0006361)
0.0 0.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.1 GO:0035383 acyl-CoA metabolic process(GO:0006637) thioester metabolic process(GO:0035383)
0.0 0.1 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.3 GO:0045670 regulation of osteoclast differentiation(GO:0045670)
0.0 0.6 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.4 GO:0006506 GPI anchor biosynthetic process(GO:0006506)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
4.7 14.2 GO:0097512 cardiac myofibril(GO:0097512)
2.9 8.7 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
2.1 6.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
1.7 8.5 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
1.0 3.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.9 28.5 GO:0060077 inhibitory synapse(GO:0060077)
0.8 9.9 GO:0097542 ciliary tip(GO:0097542)
0.7 7.6 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.7 6.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.6 1.7 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.5 4.9 GO:0030478 actin cap(GO:0030478)
0.5 3.6 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.5 14.3 GO:0030673 axolemma(GO:0030673)
0.5 5.5 GO:0072546 ER membrane protein complex(GO:0072546)
0.4 5.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.4 7.1 GO:0097228 sperm principal piece(GO:0097228)
0.3 1.4 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.3 1.0 GO:0097447 dendritic tree(GO:0097447)
0.3 1.7 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.3 10.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.3 1.4 GO:0008290 F-actin capping protein complex(GO:0008290)
0.3 8.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.2 3.5 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.2 19.2 GO:0031594 neuromuscular junction(GO:0031594)
0.2 3.5 GO:0031143 pseudopodium(GO:0031143)
0.2 1.2 GO:0044294 dendritic growth cone(GO:0044294)
0.2 0.4 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 1.8 GO:0000138 Golgi trans cisterna(GO:0000138)
0.2 0.4 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.2 2.3 GO:0005922 connexon complex(GO:0005922)
0.2 3.0 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.2 0.6 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.2 0.8 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.1 4.0 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 7.3 GO:0009925 basal plasma membrane(GO:0009925)
0.1 1.4 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 2.9 GO:0048786 presynaptic active zone(GO:0048786)
0.1 0.7 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 1.0 GO:0072687 meiotic spindle(GO:0072687)
0.1 2.1 GO:0097386 glial cell projection(GO:0097386)
0.1 1.0 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 1.0 GO:0000815 ESCRT III complex(GO:0000815)
0.1 3.0 GO:0032589 neuron projection membrane(GO:0032589)
0.1 5.6 GO:0005905 clathrin-coated pit(GO:0005905)
0.1 2.6 GO:0045178 basal part of cell(GO:0045178)
0.1 0.6 GO:0000322 storage vacuole(GO:0000322)
0.1 20.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 3.5 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.1 1.7 GO:0030139 endocytic vesicle(GO:0030139)
0.1 4.4 GO:0001750 photoreceptor outer segment(GO:0001750)
0.1 1.4 GO:0000145 exocyst(GO:0000145)
0.1 1.0 GO:0043194 axon initial segment(GO:0043194)
0.1 5.3 GO:0030175 filopodium(GO:0030175)
0.1 14.5 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.1 0.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 1.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 2.4 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 11.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 3.7 GO:0005798 Golgi-associated vesicle(GO:0005798)
0.1 12.7 GO:0098852 lysosomal membrane(GO:0005765) lytic vacuole membrane(GO:0098852)
0.1 1.9 GO:0031941 filamentous actin(GO:0031941)
0.1 17.4 GO:0005925 focal adhesion(GO:0005925)
0.0 0.4 GO:0070688 MLL5-L complex(GO:0070688)
0.0 0.4 GO:0031902 late endosome membrane(GO:0031902)
0.0 1.0 GO:0030315 T-tubule(GO:0030315)
0.0 0.9 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 20.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 3.4 GO:0043204 perikaryon(GO:0043204)
0.0 1.4 GO:0035869 ciliary transition zone(GO:0035869)
0.0 4.0 GO:0030017 sarcomere(GO:0030017)
0.0 1.5 GO:0097060 synaptic membrane(GO:0097060)
0.0 1.4 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0030870 Mre11 complex(GO:0030870)
0.0 4.8 GO:0043235 receptor complex(GO:0043235)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 1.4 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0061617 MICOS complex(GO:0061617)
0.0 1.3 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.7 GO:0016459 myosin complex(GO:0016459)
0.0 0.7 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 1.9 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0030057 desmosome(GO:0030057)
0.0 0.5 GO:0005902 microvillus(GO:0005902)
0.0 1.2 GO:0005770 late endosome(GO:0005770)
0.0 0.6 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.3 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.9 GO:0005643 nuclear pore(GO:0005643)
0.0 0.4 GO:0005801 cis-Golgi network(GO:0005801)
0.0 1.5 GO:0030141 secretory granule(GO:0030141)
0.0 0.3 GO:0098797 plasma membrane protein complex(GO:0098797)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
2.1 6.4 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
2.0 8.1 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)
1.5 9.1 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
1.4 8.5 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
1.3 3.9 GO:0070905 serine binding(GO:0070905)
1.3 9.0 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
1.3 11.5 GO:0005212 structural constituent of eye lens(GO:0005212)
1.2 8.7 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
1.2 13.6 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.2 4.8 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
1.2 3.5 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
1.1 6.8 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
1.1 3.4 GO:0035939 microsatellite binding(GO:0035939)
1.1 3.4 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.9 16.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.9 3.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.8 3.4 GO:2001069 glycogen binding(GO:2001069)
0.8 7.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.8 4.1 GO:0038132 neuregulin binding(GO:0038132)
0.8 4.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.8 5.5 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.7 5.9 GO:0048495 Roundabout binding(GO:0048495)
0.7 12.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.6 4.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.6 1.9 GO:0005119 smoothened binding(GO:0005119) hedgehog receptor activity(GO:0008158) hedgehog family protein binding(GO:0097108)
0.6 2.5 GO:0004096 catalase activity(GO:0004096)
0.6 8.0 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.6 5.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.5 2.7 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.5 1.6 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.5 2.6 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.5 3.0 GO:0005042 netrin receptor activity(GO:0005042)
0.5 1.9 GO:0003884 D-amino-acid oxidase activity(GO:0003884) aspartate oxidase activity(GO:0015922)
0.5 1.9 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.5 1.8 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.5 1.4 GO:0032052 bile acid binding(GO:0032052)
0.5 8.2 GO:0015026 coreceptor activity(GO:0015026)
0.5 5.9 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.4 1.8 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.4 2.6 GO:0061505 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.4 3.0 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.4 2.0 GO:0045545 syndecan binding(GO:0045545)
0.4 8.7 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.4 2.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.3 2.1 GO:0015265 urea channel activity(GO:0015265)
0.3 2.0 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.3 1.0 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.3 2.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.3 2.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 1.4 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.3 1.0 GO:0004609 phosphatidylserine decarboxylase activity(GO:0004609)
0.2 3.8 GO:0001223 transcription coactivator binding(GO:0001223)
0.2 0.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 1.4 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.2 0.8 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 2.3 GO:0005243 gap junction channel activity(GO:0005243)
0.2 4.6 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.2 3.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 6.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.2 1.0 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.2 1.7 GO:0048406 nerve growth factor binding(GO:0048406)
0.2 3.6 GO:0070628 proteasome binding(GO:0070628)
0.2 3.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.2 0.5 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.2 0.7 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.2 5.0 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 0.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 3.5 GO:0003785 actin monomer binding(GO:0003785)
0.1 3.1 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.1 2.4 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 0.7 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 1.5 GO:0048038 quinone binding(GO:0048038)
0.1 1.4 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.1 1.3 GO:0044548 S100 protein binding(GO:0044548)
0.1 15.7 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 0.4 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 3.8 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.1 1.2 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.6 GO:0051425 PTB domain binding(GO:0051425)
0.1 4.3 GO:0070888 E-box binding(GO:0070888)
0.1 3.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 1.0 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.1 2.0 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.1 1.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.3 GO:0005522 profilin binding(GO:0005522)
0.1 4.1 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.1 5.7 GO:0030276 clathrin binding(GO:0030276)
0.1 1.0 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 1.7 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.1 2.8 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.1 1.0 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.1 1.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.1 8.1 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.1 0.9 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 0.6 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.9 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.1 3.5 GO:0015459 potassium channel regulator activity(GO:0015459)
0.1 1.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 5.4 GO:0005262 calcium channel activity(GO:0005262)
0.1 6.3 GO:0005125 cytokine activity(GO:0005125)
0.1 2.2 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.1 0.3 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.1 1.4 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.5 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 1.1 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.1 2.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.1 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 2.3 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 4.6 GO:0008201 heparin binding(GO:0008201)
0.0 0.5 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 2.3 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 2.7 GO:0017022 myosin binding(GO:0017022)
0.0 5.7 GO:0044325 ion channel binding(GO:0044325)
0.0 13.6 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.0 7.5 GO:0005516 calmodulin binding(GO:0005516)
0.0 4.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 3.5 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0001134 transcription factor activity, transcription factor recruiting(GO:0001134)
0.0 4.4 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.7 GO:0005112 Notch binding(GO:0005112) retinoid X receptor binding(GO:0046965)
0.0 0.4 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 1.6 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 1.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0003945 N-acetyllactosamine synthase activity(GO:0003945)
0.0 0.1 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.3 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 3.9 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.0 1.0 GO:0019894 kinesin binding(GO:0019894)
0.0 1.2 GO:0000149 SNARE binding(GO:0000149)
0.0 2.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.0 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 13.3 GO:0046983 protein dimerization activity(GO:0046983)
0.0 0.9 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.3 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)