Motif ID: Gmeb1

Z-value: 0.574


Transcription factors associated with Gmeb1:

Gene SymbolEntrez IDGene Name
Gmeb1 ENSMUSG00000028901.7 Gmeb1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gmeb1mm10_v2_chr4_-_132261596_1322616220.506.2e-05Click!


Activity profile for motif Gmeb1.

activity profile for motif Gmeb1


Sorted Z-values histogram for motif Gmeb1

Sorted Z-values for motif Gmeb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gmeb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 81 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_175880775 4.742 ENSMUST00000039725.6
 Exo1
exonuclease 1
chr6_+_113531675 4.344 ENSMUST00000036340.5
ENSMUST00000101051.2
 Fancd2

Fanconi anemia, complementation group D2

chr17_+_23679363 3.860 ENSMUST00000024699.2
 Cldn6
claudin 6
chr3_+_40800054 3.605 ENSMUST00000168287.1
 Plk4
polo-like kinase 4
chr2_-_157007039 3.554 ENSMUST00000103129.2
ENSMUST00000103130.1
 Dsn1

DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)

chr2_-_157007015 3.408 ENSMUST00000146413.1
 Dsn1
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr3_+_40800013 3.076 ENSMUST00000026858.5
ENSMUST00000170825.1
 Plk4

polo-like kinase 4

chr13_-_53473074 2.802 ENSMUST00000021922.8
 Msx2
msh homeobox 2
chr3_+_127553462 2.667 ENSMUST00000043108.4
 4930422G04Rik
RIKEN cDNA 4930422G04 gene
chrX_+_112311334 2.397 ENSMUST00000026599.3
ENSMUST00000113415.1
 Apool

apolipoprotein O-like

chr17_+_84511832 2.390 ENSMUST00000047206.5
 Plekhh2
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr2_+_75659253 2.387 ENSMUST00000111964.1
ENSMUST00000111962.1
ENSMUST00000111961.1
ENSMUST00000164947.2
ENSMUST00000090792.4
 Hnrnpa3




heterogeneous nuclear ribonucleoprotein A3




chr11_-_100822525 2.230 ENSMUST00000107358.2
 Stat5b
signal transducer and activator of transcription 5B
chr3_+_138143429 2.221 ENSMUST00000040321.6
 Trmt10a
tRNA methyltransferase 10A
chr15_+_99074968 2.209 ENSMUST00000039665.6
 Troap
trophinin associated protein
chr19_+_43612299 2.191 ENSMUST00000057178.9
 Nkx2-3
NK2 homeobox 3
chr3_-_138143352 1.993 ENSMUST00000098580.2
 Mttp
microsomal triglyceride transfer protein
chr3_+_138143483 1.912 ENSMUST00000162864.1
 Trmt10a
tRNA methyltransferase 10A
chr11_-_40733373 1.899 ENSMUST00000020579.8
 Hmmr
hyaluronan mediated motility receptor (RHAMM)
chr11_+_86544982 1.694 ENSMUST00000108030.2
ENSMUST00000020821.3
ENSMUST00000069503.6
ENSMUST00000167178.2
 Tubd1



tubulin, delta 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 6.7 GO:0046601 positive regulation of centriole replication(GO:0046601)
0.5 4.7 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.6 4.3 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 4.1 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.0 3.9 GO:0045216 cell-cell junction organization(GO:0045216)
0.0 3.2 GO:0007059 chromosome segregation(GO:0007059)
0.9 2.8 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.1 2.4 GO:0042407 cristae formation(GO:0042407)
0.0 2.4 GO:0030835 negative regulation of actin filament depolymerization(GO:0030835)
0.0 2.4 GO:0051028 mRNA transport(GO:0051028)
0.8 2.3 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.7 2.2 GO:0046544 regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) development of secondary male sexual characteristics(GO:0046544)
0.4 2.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.4 2.0 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 1.8 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.1 1.6 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 1.5 GO:0019395 fatty acid oxidation(GO:0019395)
0.2 1.4 GO:0061084 negative regulation of protein refolding(GO:0061084)
0.2 1.4 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.4 1.3 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.2 7.0 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.8 6.7 GO:0098536 deuterosome(GO:0098536)
0.0 4.3 GO:0000793 condensed chromosome(GO:0000793)
0.2 3.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 2.5 GO:0005681 spliceosomal complex(GO:0005681)
0.3 2.4 GO:0061617 MICOS complex(GO:0061617)
0.1 2.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 2.4 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.2 2.3 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 2.0 GO:0031528 microvillus membrane(GO:0031528)
0.0 1.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.6 GO:0016459 myosin complex(GO:0016459)
0.1 1.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 1.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 1.2 GO:0097539 ciliary transition fiber(GO:0097539)
0.3 1.1 GO:0071942 XPC complex(GO:0071942)
0.1 0.9 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0035102 PRC1 complex(GO:0035102)
0.2 0.6 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.3 4.9 GO:0070182 DNA polymerase binding(GO:0070182)
1.2 4.7 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297) double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.1 4.1 GO:0000049 tRNA binding(GO:0000049)
0.0 2.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.6 2.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 2.3 GO:0043236 laminin binding(GO:0043236)
0.1 2.2 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.1 2.0 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 1.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 1.8 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 1.7 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.6 GO:0003774 motor activity(GO:0003774)
0.1 1.5 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.2 1.4 GO:0032564 dATP binding(GO:0032564)
0.1 1.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.4 1.3 GO:0017084 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.0 1.1 GO:0003684 damaged DNA binding(GO:0003684)
0.3 1.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.1 1.0 GO:0071949 FAD binding(GO:0071949)
0.2 0.9 GO:0033592 RNA strand annealing activity(GO:0033592)