Motif ID: Gmeb2
Z-value: 0.491
Transcription factors associated with Gmeb2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Gmeb2 | ENSMUSG00000038705.7 | Gmeb2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Gmeb2 | mm10_v2_chr2_-_181288016_181288041 | 0.10 | 4.4e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.4 | 1.3 | GO:0032696 | negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153) odontoblast differentiation(GO:0071895) regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899) |
0.4 | 1.3 | GO:0006592 | ornithine biosynthetic process(GO:0006592) |
0.2 | 0.6 | GO:0035574 | histone H4-K20 demethylation(GO:0035574) |
0.2 | 0.9 | GO:0043985 | histone H4-R3 methylation(GO:0043985) |
0.2 | 0.5 | GO:0097155 | fasciculation of sensory neuron axon(GO:0097155) |
0.2 | 0.5 | GO:0042939 | glutathione transport(GO:0034635) oligopeptide transmembrane transport(GO:0035672) xenobiotic transport(GO:0042908) tripeptide transport(GO:0042939) |
0.2 | 2.6 | GO:0010225 | response to UV-C(GO:0010225) |
0.2 | 0.6 | GO:0042796 | snRNA transcription from RNA polymerase III promoter(GO:0042796) |
0.2 | 0.5 | GO:0007290 | spermatid nucleus elongation(GO:0007290) |
0.1 | 0.5 | GO:0090365 | regulation of mRNA modification(GO:0090365) |
0.1 | 0.8 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
0.1 | 0.4 | GO:0006990 | positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) |
0.1 | 0.6 | GO:2000987 | positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987) |
0.1 | 1.0 | GO:2000301 | negative regulation of synaptic vesicle exocytosis(GO:2000301) |
0.1 | 0.5 | GO:0046654 | 'de novo' IMP biosynthetic process(GO:0006189) tetrahydrofolate biosynthetic process(GO:0046654) |
0.1 | 0.4 | GO:0071475 | cellular hyperosmotic salinity response(GO:0071475) |
0.1 | 0.3 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.1 | 0.3 | GO:0002842 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) |
0.1 | 0.3 | GO:0060743 | epithelial cell maturation involved in prostate gland development(GO:0060743) alveolar secondary septum development(GO:0061144) |
0.1 | 0.3 | GO:0015014 | heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014) |
0.1 | 0.8 | GO:0030174 | regulation of DNA-dependent DNA replication initiation(GO:0030174) mitotic DNA replication checkpoint(GO:0033314) |
0.1 | 0.3 | GO:0000965 | mitochondrial RNA 3'-end processing(GO:0000965) |
0.1 | 0.7 | GO:0031053 | primary miRNA processing(GO:0031053) |
0.1 | 0.4 | GO:0015692 | vanadium ion transport(GO:0015676) lead ion transport(GO:0015692) |
0.1 | 0.1 | GO:0033122 | regulation of purine nucleotide catabolic process(GO:0033121) negative regulation of purine nucleotide catabolic process(GO:0033122) |
0.1 | 3.2 | GO:0007218 | neuropeptide signaling pathway(GO:0007218) |
0.1 | 0.4 | GO:0021764 | amygdala development(GO:0021764) |
0.1 | 0.3 | GO:2000271 | positive regulation of fibroblast apoptotic process(GO:2000271) |
0.1 | 0.6 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
0.1 | 1.1 | GO:0070986 | left/right axis specification(GO:0070986) |
0.1 | 0.4 | GO:2000210 | positive regulation of anoikis(GO:2000210) |
0.1 | 0.4 | GO:0032929 | negative regulation of superoxide anion generation(GO:0032929) negative regulation of amyloid precursor protein biosynthetic process(GO:0042985) |
0.1 | 0.3 | GO:0018125 | peptidyl-cysteine methylation(GO:0018125) |
0.1 | 1.3 | GO:0046033 | AMP metabolic process(GO:0046033) |
0.1 | 0.3 | GO:0045347 | negative regulation of MHC class II biosynthetic process(GO:0045347) |
0.0 | 0.3 | GO:0045908 | negative regulation of vasodilation(GO:0045908) |
0.0 | 0.4 | GO:0016446 | somatic hypermutation of immunoglobulin genes(GO:0016446) |
0.0 | 0.3 | GO:1903441 | protein localization to ciliary membrane(GO:1903441) |
0.0 | 0.2 | GO:1902626 | assembly of large subunit precursor of preribosome(GO:1902626) |
0.0 | 0.4 | GO:0033148 | positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148) |
0.0 | 0.3 | GO:0008298 | intracellular mRNA localization(GO:0008298) |
0.0 | 0.5 | GO:0006614 | SRP-dependent cotranslational protein targeting to membrane(GO:0006614) |
0.0 | 0.3 | GO:0030432 | peristalsis(GO:0030432) |
0.0 | 0.1 | GO:1904742 | regulation of telomeric DNA binding(GO:1904742) |
0.0 | 0.1 | GO:0006438 | valyl-tRNA aminoacylation(GO:0006438) |
0.0 | 0.1 | GO:0050975 | sensory perception of touch(GO:0050975) |
0.0 | 1.0 | GO:0007638 | mechanosensory behavior(GO:0007638) |
0.0 | 0.8 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
0.0 | 0.3 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
0.0 | 0.2 | GO:0050861 | positive regulation of B cell receptor signaling pathway(GO:0050861) |
0.0 | 0.1 | GO:0031509 | telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340) |
0.0 | 0.1 | GO:0009106 | lipoate metabolic process(GO:0009106) |
0.0 | 0.1 | GO:1903031 | regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033) |
0.0 | 0.3 | GO:0090435 | protein localization to nuclear envelope(GO:0090435) |
0.0 | 0.3 | GO:0061088 | sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) |
0.0 | 0.4 | GO:0034497 | protein localization to pre-autophagosomal structure(GO:0034497) |
0.0 | 0.1 | GO:0032511 | regulation of multivesicular body size(GO:0010796) late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
0.0 | 0.1 | GO:0071787 | endoplasmic reticulum tubular network assembly(GO:0071787) |
0.0 | 0.4 | GO:0006337 | nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986) |
0.0 | 0.2 | GO:0070234 | positive regulation of T cell apoptotic process(GO:0070234) |
0.0 | 0.2 | GO:0045654 | positive regulation of megakaryocyte differentiation(GO:0045654) |
0.0 | 0.4 | GO:0051457 | maintenance of protein location in nucleus(GO:0051457) |
0.0 | 0.5 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
0.0 | 0.3 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.0 | 0.3 | GO:0016926 | protein desumoylation(GO:0016926) |
0.0 | 0.4 | GO:0007274 | neuromuscular synaptic transmission(GO:0007274) |
0.0 | 0.1 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
0.0 | 0.1 | GO:0031145 | anaphase-promoting complex-dependent catabolic process(GO:0031145) |
0.0 | 0.6 | GO:0006284 | base-excision repair(GO:0006284) |
0.0 | 0.1 | GO:1900242 | circadian sleep/wake cycle, non-REM sleep(GO:0042748) regulation of synaptic vesicle endocytosis(GO:1900242) |
0.0 | 0.8 | GO:0030835 | negative regulation of actin filament depolymerization(GO:0030835) |
0.0 | 0.4 | GO:0000413 | protein peptidyl-prolyl isomerization(GO:0000413) |
0.0 | 0.2 | GO:0015693 | magnesium ion transport(GO:0015693) |
0.0 | 0.2 | GO:0045910 | negative regulation of DNA recombination(GO:0045910) |
0.0 | 0.8 | GO:0035904 | aorta development(GO:0035904) |
0.0 | 0.5 | GO:0000462 | maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462) |
0.0 | 0.2 | GO:0009263 | deoxyribonucleotide biosynthetic process(GO:0009263) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.2 | 0.6 | GO:0043540 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540) |
0.2 | 0.6 | GO:0032280 | symmetric synapse(GO:0032280) |
0.1 | 1.3 | GO:1990907 | beta-catenin-TCF complex(GO:1990907) |
0.1 | 0.6 | GO:0030127 | COPII vesicle coat(GO:0030127) |
0.1 | 0.1 | GO:0061574 | ASAP complex(GO:0061574) |
0.1 | 0.5 | GO:0034388 | Pwp2p-containing subcomplex of 90S preribosome(GO:0034388) |
0.1 | 0.4 | GO:0070826 | paraferritin complex(GO:0070826) |
0.1 | 0.2 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
0.1 | 0.4 | GO:0043564 | Ku70:Ku80 complex(GO:0043564) |
0.1 | 3.2 | GO:0060170 | ciliary membrane(GO:0060170) |
0.1 | 0.8 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
0.1 | 1.6 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
0.1 | 0.5 | GO:0005786 | signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500) |
0.1 | 0.3 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
0.0 | 0.1 | GO:1990423 | RZZ complex(GO:1990423) |
0.0 | 0.1 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.0 | 0.7 | GO:0071004 | U2-type prespliceosome(GO:0071004) |
0.0 | 0.1 | GO:0000814 | ESCRT II complex(GO:0000814) |
0.0 | 0.2 | GO:0005971 | ribonucleoside-diphosphate reductase complex(GO:0005971) |
0.0 | 0.1 | GO:0042583 | chromaffin granule(GO:0042583) |
0.0 | 0.1 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
0.0 | 0.6 | GO:0001741 | XY body(GO:0001741) |
0.0 | 0.5 | GO:0005697 | telomerase holoenzyme complex(GO:0005697) |
0.0 | 0.3 | GO:0032156 | septin cytoskeleton(GO:0032156) |
0.0 | 0.2 | GO:0072357 | PTW/PP1 phosphatase complex(GO:0072357) |
0.0 | 0.8 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.0 | 0.3 | GO:0031229 | integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) |
0.0 | 0.1 | GO:0071006 | U2-type catalytic step 1 spliceosome(GO:0071006) |
0.0 | 0.1 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
0.0 | 0.3 | GO:0005736 | DNA-directed RNA polymerase I complex(GO:0005736) |
0.0 | 0.4 | GO:0070822 | Sin3-type complex(GO:0070822) |
0.0 | 0.3 | GO:0030914 | STAGA complex(GO:0030914) |
0.0 | 0.4 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
0.0 | 0.1 | GO:0070187 | telosome(GO:0070187) |
0.0 | 0.2 | GO:0000177 | cytoplasmic exosome (RNase complex)(GO:0000177) |
0.0 | 1.0 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
0.0 | 0.1 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
0.0 | 0.4 | GO:0035145 | exon-exon junction complex(GO:0035145) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 3.2 | GO:0004994 | somatostatin receptor activity(GO:0004994) |
0.4 | 1.3 | GO:0046899 | nucleoside triphosphate adenylate kinase activity(GO:0046899) |
0.4 | 1.3 | GO:0017084 | glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202) |
0.3 | 0.9 | GO:0035243 | protein-arginine omega-N symmetric methyltransferase activity(GO:0035243) |
0.3 | 1.0 | GO:0008309 | double-stranded DNA exodeoxyribonuclease activity(GO:0008309) |
0.2 | 1.3 | GO:0030284 | estrogen receptor activity(GO:0030284) |
0.2 | 0.8 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
0.2 | 0.6 | GO:0035575 | histone demethylase activity (H4-K20 specific)(GO:0035575) |
0.2 | 0.5 | GO:0004637 | phosphoribosylamine-glycine ligase activity(GO:0004637) |
0.2 | 0.5 | GO:0017150 | tRNA dihydrouridine synthase activity(GO:0017150) |
0.2 | 0.5 | GO:0015562 | efflux transmembrane transporter activity(GO:0015562) oligopeptide transmembrane transporter activity(GO:0035673) |
0.2 | 1.5 | GO:1990247 | N6-methyladenosine-containing RNA binding(GO:1990247) |
0.1 | 2.6 | GO:0097602 | cullin family protein binding(GO:0097602) |
0.1 | 0.5 | GO:0042731 | PH domain binding(GO:0042731) |
0.1 | 0.5 | GO:0005047 | signal recognition particle binding(GO:0005047) endoplasmic reticulum signal peptide binding(GO:0030942) |
0.1 | 0.3 | GO:0016309 | 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309) |
0.1 | 0.6 | GO:0001515 | opioid peptide activity(GO:0001515) |
0.1 | 0.4 | GO:0015086 | cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639) |
0.1 | 0.6 | GO:0070095 | fructose-6-phosphate binding(GO:0070095) |
0.1 | 0.4 | GO:0004427 | inorganic diphosphatase activity(GO:0004427) |
0.1 | 0.3 | GO:0046870 | cadmium ion binding(GO:0046870) |
0.1 | 0.5 | GO:0008526 | phosphatidylinositol transporter activity(GO:0008526) |
0.0 | 0.2 | GO:0030621 | U4 snRNA binding(GO:0030621) |
0.0 | 0.4 | GO:0051575 | 5'-deoxyribose-5-phosphate lyase activity(GO:0051575) |
0.0 | 0.2 | GO:0000403 | Y-form DNA binding(GO:0000403) |
0.0 | 0.6 | GO:0070008 | serine-type exopeptidase activity(GO:0070008) |
0.0 | 0.5 | GO:0034951 | pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011) |
0.0 | 0.3 | GO:0043559 | insulin binding(GO:0043559) |
0.0 | 0.3 | GO:0031685 | adenosine receptor binding(GO:0031685) |
0.0 | 1.0 | GO:0031624 | ubiquitin conjugating enzyme binding(GO:0031624) |
0.0 | 1.0 | GO:0031434 | mitogen-activated protein kinase kinase binding(GO:0031434) |
0.0 | 0.3 | GO:0008097 | 5S rRNA binding(GO:0008097) |
0.0 | 0.2 | GO:0061731 | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731) |
0.0 | 0.1 | GO:0004832 | valine-tRNA ligase activity(GO:0004832) |
0.0 | 0.4 | GO:0036312 | phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312) |
0.0 | 0.2 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
0.0 | 0.4 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
0.0 | 0.7 | GO:0019789 | SUMO transferase activity(GO:0019789) |
0.0 | 0.6 | GO:0070064 | proline-rich region binding(GO:0070064) |
0.0 | 0.3 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
0.0 | 0.4 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 0.3 | GO:0001054 | RNA polymerase I activity(GO:0001054) |
0.0 | 1.2 | GO:0003725 | double-stranded RNA binding(GO:0003725) |
0.0 | 0.4 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.5 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
0.0 | 0.1 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
0.0 | 0.0 | GO:0015450 | P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450) |
0.0 | 0.5 | GO:0004364 | glutathione transferase activity(GO:0004364) |
0.0 | 0.9 | GO:0030276 | clathrin binding(GO:0030276) |
0.0 | 0.1 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
0.0 | 0.2 | GO:0015095 | magnesium ion transmembrane transporter activity(GO:0015095) |
0.0 | 0.2 | GO:0070402 | NADPH binding(GO:0070402) |
0.0 | 0.5 | GO:0008748 | N-ethylmaleimide reductase activity(GO:0008748) reduced coenzyme F420 dehydrogenase activity(GO:0043738) sulfur oxygenase reductase activity(GO:0043826) malolactic enzyme activity(GO:0043883) epoxyqueuosine reductase activity(GO:0052693) |
0.0 | 0.4 | GO:0051059 | NF-kappaB binding(GO:0051059) |
0.0 | 0.1 | GO:0051010 | microtubule plus-end binding(GO:0051010) |