Motif ID: Gsc2_Dmbx1

Z-value: 0.540

Transcription factors associated with Gsc2_Dmbx1:

Gene SymbolEntrez IDGene Name
Dmbx1 ENSMUSG00000028707.9 Dmbx1
Gsc2 ENSMUSG00000022738.6 Gsc2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Dmbx1mm10_v2_chr4_-_115939923_115939928-0.019.4e-01Click!


Activity profile for motif Gsc2_Dmbx1.

activity profile for motif Gsc2_Dmbx1


Sorted Z-values histogram for motif Gsc2_Dmbx1

Sorted Z-values for motif Gsc2_Dmbx1



Network of associatons between targets according to the STRING database.



First level regulatory network of Gsc2_Dmbx1

PNG image of the network

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Top targets:


Showing 1 to 20 of 100 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_137766474 5.967 ENSMUST00000139951.1
 Alpl
alkaline phosphatase, liver/bone/kidney
chr5_+_77265454 2.993 ENSMUST00000080359.5
 Rest
RE1-silencing transcription factor
chr14_-_118052235 2.935 ENSMUST00000022725.2
 Dct
dopachrome tautomerase
chr7_-_133015248 2.906 ENSMUST00000169570.1
 Ctbp2
C-terminal binding protein 2
chr11_-_52282564 2.883 ENSMUST00000086844.3
 Tcf7
transcription factor 7, T cell specific
chr17_+_35861318 2.710 ENSMUST00000074259.8
ENSMUST00000174873.1
 Nrm

nurim (nuclear envelope membrane protein)

chr2_+_91259822 2.175 ENSMUST00000138470.1
 Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr17_+_35861343 2.140 ENSMUST00000172931.1
 Nrm
nurim (nuclear envelope membrane protein)
chr2_+_164562579 2.083 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
 Wfdc2


WAP four-disulfide core domain 2


chr9_+_50617516 1.967 ENSMUST00000141366.1
 Pih1d2
PIH1 domain containing 2
chr10_-_22149270 1.913 ENSMUST00000179054.1
ENSMUST00000069372.6
 E030030I06Rik

RIKEN cDNA E030030I06 gene

chr4_+_154960915 1.886 ENSMUST00000049621.6
 Hes5
hairy and enhancer of split 5 (Drosophila)
chr1_+_44551483 1.679 ENSMUST00000074525.3
 Gulp1
GULP, engulfment adaptor PTB domain containing 1
chr4_-_141053660 1.609 ENSMUST00000040222.7
 Crocc
ciliary rootlet coiled-coil, rootletin
chr17_-_58991343 1.539 ENSMUST00000025064.7
 2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr14_-_31640878 1.468 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
 Hacl1


2-hydroxyacyl-CoA lyase 1


chr11_-_68973840 1.430 ENSMUST00000038644.4
 Rangrf
RAN guanine nucleotide release factor
chr19_-_12765447 1.400 ENSMUST00000112933.1
 Cntf
ciliary neurotrophic factor
chr5_+_3344194 1.354 ENSMUST00000042410.4
 Cdk6
cyclin-dependent kinase 6
chr8_+_13405080 1.330 ENSMUST00000033827.7
 Grk1
G protein-coupled receptor kinase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.0 GO:0046677 response to antibiotic(GO:0046677)
0.3 3.4 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.7 3.0 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.1 3.0 GO:0006911 phagocytosis, engulfment(GO:0006911)
0.5 2.9 GO:0006570 tyrosine metabolic process(GO:0006570)
0.4 2.9 GO:0002681 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.9 2.7 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.7 2.2 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 2.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 2.1 GO:0010466 negative regulation of peptidase activity(GO:0010466)
0.5 1.9 GO:2000974 negative regulation of pro-B cell differentiation(GO:2000974)
0.3 1.6 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.3 1.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.3 1.4 GO:0046533 negative regulation of photoreceptor cell differentiation(GO:0046533)
0.1 1.4 GO:2000010 positive regulation of protein localization to cell surface(GO:2000010)
0.4 1.3 GO:0016056 photoreceptor cell morphogenesis(GO:0008594) rhodopsin mediated signaling pathway(GO:0016056) post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0 1.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 1.3 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 1.1 GO:0043171 peptide catabolic process(GO:0043171)
0.0 1.1 GO:0007601 visual perception(GO:0007601)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 22 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 6.0 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.3 4.8 GO:0005652 nuclear lamina(GO:0005652)
0.2 3.4 GO:0097470 ribbon synapse(GO:0097470)
0.0 3.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 2.9 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 2.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 2.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 2.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 1.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.6 GO:0030673 axolemma(GO:0030673)
0.5 1.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.0 1.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 1.3 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.0 1.0 GO:0030315 T-tubule(GO:0030315)
0.0 0.9 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.9 GO:0015030 Cajal body(GO:0015030)
0.0 0.9 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.6 GO:0030677 nucleolar ribonuclease P complex(GO:0005655) ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 6.0 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 3.4 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.2 3.0 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.2 2.9 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 2.9 GO:0008013 beta-catenin binding(GO:0008013)
0.1 2.7 GO:0030332 cyclin binding(GO:0030332)
0.3 2.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.1 2.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 2.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 2.2 GO:0019894 kinesin binding(GO:0019894)
0.0 2.1 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.1 2.0 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 1.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.4 1.6 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 1.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.2 1.3 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 1.3 GO:0030276 clathrin binding(GO:0030276)
0.3 1.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.1 1.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 1.0 GO:0031432 titin binding(GO:0031432)