Motif ID: Gsx2_Hoxd3_Vax1

Z-value: 0.694

Transcription factors associated with Gsx2_Hoxd3_Vax1:

Gene SymbolEntrez IDGene Name
Gsx2 ENSMUSG00000035946.6 Gsx2
Hoxd3 ENSMUSG00000079277.3 Hoxd3
Vax1 ENSMUSG00000006270.6 Vax1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Gsx2mm10_v2_chr5_+_75075464_750756010.471.9e-04Click!
Vax1mm10_v2_chr19_-_59170978_591709780.357.1e-03Click!





Network of associatons between targets according to the STRING database.



First level regulatory network of Gsx2_Hoxd3_Vax1

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_48662740 10.456 ENSMUST00000122009.1
Otx2
orthodenticle homolog 2 (Drosophila)
chr2_+_109917639 9.626 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr9_+_119063429 8.725 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr2_-_168767136 8.533 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr2_-_168767029 6.263 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr15_+_25773985 5.064 ENSMUST00000125667.1
Myo10
myosin X
chr19_+_55895508 4.799 ENSMUST00000111646.1
Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr13_-_53473074 4.633 ENSMUST00000021922.8
Msx2
msh homeobox 2
chr18_+_56432116 4.182 ENSMUST00000070166.5
Gramd3
GRAM domain containing 3
chr4_+_8690399 4.180 ENSMUST00000127476.1
Chd7
chromodomain helicase DNA binding protein 7
chr6_-_23248264 3.721 ENSMUST00000031709.5
Fezf1
Fez family zinc finger 1
chr9_-_90255927 3.380 ENSMUST00000144646.1
Tbc1d2b
TBC1 domain family, member 2B
chr3_+_159839729 3.366 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr6_-_34317442 2.768 ENSMUST00000154655.1
ENSMUST00000102980.4
Akr1b3

aldo-keto reductase family 1, member B3 (aldose reductase)

chr11_+_59306920 2.727 ENSMUST00000000128.3
ENSMUST00000108783.3
Wnt9a

wingless-type MMTV integration site 9A

chr17_-_70853482 2.670 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr12_-_55014329 2.579 ENSMUST00000172875.1
Baz1a
bromodomain adjacent to zinc finger domain 1A
chr5_+_138187485 2.561 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr2_+_120476911 2.543 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
Capn3



calpain 3



chr3_+_55782500 2.531 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr13_-_102905740 2.395 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr2_-_28916412 2.375 ENSMUST00000050776.2
ENSMUST00000113849.1
Barhl1

BarH-like 1 (Drosophila)

chrX_+_150547375 2.352 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr13_-_102906046 2.282 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr13_+_51408618 2.281 ENSMUST00000087978.3
S1pr3
sphingosine-1-phosphate receptor 3
chr12_+_112760652 2.176 ENSMUST00000063888.3
Pld4
phospholipase D family, member 4
chr10_+_128337761 2.129 ENSMUST00000005826.7
Cs
citrate synthase
chr12_+_38780284 2.057 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
Etv1


ets variant gene 1


chr2_+_91457501 1.891 ENSMUST00000028689.3
Lrp4
low density lipoprotein receptor-related protein 4
chr10_+_128083273 1.805 ENSMUST00000026459.5
Atp5b
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr14_+_48446128 1.791 ENSMUST00000124720.1
Tmem260
transmembrane protein 260
chr2_-_28916668 1.749 ENSMUST00000113847.1
Barhl1
BarH-like 1 (Drosophila)
chr2_-_120154600 1.720 ENSMUST00000028755.7
Ehd4
EH-domain containing 4
chr12_+_38780817 1.646 ENSMUST00000160856.1
Etv1
ets variant gene 1
chr18_+_57142782 1.589 ENSMUST00000139892.1
Megf10
multiple EGF-like-domains 10
chr12_+_38781093 1.587 ENSMUST00000161513.1
Etv1
ets variant gene 1
chr10_-_8886033 1.573 ENSMUST00000015449.5
Sash1
SAM and SH3 domain containing 1
chr11_+_114851507 1.561 ENSMUST00000177952.1
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr2_+_36230426 1.552 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr2_+_71389239 1.514 ENSMUST00000028408.2
Hat1
histone aminotransferase 1
chrX_-_101086020 1.431 ENSMUST00000113710.1
Slc7a3
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chr5_-_138187177 1.392 ENSMUST00000110937.1
ENSMUST00000139276.1
ENSMUST00000048698.7
ENSMUST00000123415.1
Taf6



TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor



chr14_+_47298260 1.369 ENSMUST00000166743.1
Mapk1ip1l
mitogen-activated protein kinase 1 interacting protein 1-like
chr15_+_39006272 1.353 ENSMUST00000179165.1
ENSMUST00000022906.7
Fzd6

frizzled homolog 6 (Drosophila)

chr17_+_17402672 1.227 ENSMUST00000115576.2
Lix1
limb expression 1 homolog (chicken)
chr15_-_63997969 1.185 ENSMUST00000164532.1
Fam49b
family with sequence similarity 49, member B
chr1_+_78310295 1.175 ENSMUST00000036172.8
Sgpp2
sphingosine-1-phosphate phosphotase 2
chr12_-_79296266 1.172 ENSMUST00000021547.6
Zfyve26
zinc finger, FYVE domain containing 26
chr14_+_69347587 1.150 ENSMUST00000064831.5
Entpd4
ectonucleoside triphosphate diphosphohydrolase 4
chr4_-_42661893 1.114 ENSMUST00000108006.3
Il11ra2
interleukin 11 receptor, alpha chain 2
chr15_-_37459327 1.096 ENSMUST00000119730.1
ENSMUST00000120746.1
Ncald

neurocalcin delta

chr1_+_161070767 1.063 ENSMUST00000111618.1
ENSMUST00000111620.3
ENSMUST00000028035.7
Cenpl


centromere protein L


chr1_-_163725123 1.022 ENSMUST00000159679.1
Mettl11b
methyltransferase like 11B
chr3_-_33082004 0.999 ENSMUST00000108225.3
Pex5l
peroxisomal biogenesis factor 5-like
chr5_+_48242549 0.983 ENSMUST00000172493.1
Slit2
slit homolog 2 (Drosophila)
chr3_+_66219909 0.968 ENSMUST00000029421.5
Ptx3
pentraxin related gene
chr7_+_101896340 0.933 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
Anapc15


anaphase prompoting complex C subunit 15


chr14_+_79515618 0.931 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr14_+_25980039 0.925 ENSMUST00000173155.1
Duxbl1
double homeobox B-like 1
chr3_-_59220150 0.922 ENSMUST00000170388.1
P2ry12
purinergic receptor P2Y, G-protein coupled 12
chr5_-_137072254 0.917 ENSMUST00000077523.3
ENSMUST00000041388.4
Serpine1

serine (or cysteine) peptidase inhibitor, clade E, member 1

chr16_-_89818338 0.917 ENSMUST00000164263.2
Tiam1
T cell lymphoma invasion and metastasis 1
chr2_+_19371636 0.908 ENSMUST00000023856.8
Msrb2
methionine sulfoxide reductase B2
chr3_+_5218516 0.905 ENSMUST00000175866.1
Zfhx4
zinc finger homeodomain 4
chr4_-_129227883 0.904 ENSMUST00000106051.1
C77080
expressed sequence C77080
chr14_+_26259109 0.856 ENSMUST00000174494.1
Duxbl3
double homeobox B-like 3
chr4_-_117682233 0.850 ENSMUST00000102687.3
Dmap1
DNA methyltransferase 1-associated protein 1
chr3_+_125404072 0.845 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr2_+_91257323 0.834 ENSMUST00000111349.2
ENSMUST00000131711.1
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr14_+_118854695 0.828 ENSMUST00000100314.3
Cldn10
claudin 10
chr3_+_125404292 0.804 ENSMUST00000144344.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr5_-_62765618 0.778 ENSMUST00000159470.1
Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr14_+_26119811 0.772 ENSMUST00000173617.1
Duxbl2
doubl homeobox B-like 2
chr5_-_149051300 0.762 ENSMUST00000110505.1
Hmgb1
high mobility group box 1
chrX_-_160138375 0.753 ENSMUST00000033662.8
Pdha1
pyruvate dehydrogenase E1 alpha 1
chr3_+_19187321 0.706 ENSMUST00000130806.1
ENSMUST00000117529.1
ENSMUST00000119865.1
Mtfr1


mitochondrial fission regulator 1


chrX_+_169685191 0.698 ENSMUST00000112104.1
ENSMUST00000112107.1
Mid1

midline 1

chr2_-_91649751 0.692 ENSMUST00000099714.3
Zfp408
zinc finger protein 408
chr14_-_52104015 0.690 ENSMUST00000111610.4
ENSMUST00000164655.1
Hnrnpc

heterogeneous nuclear ribonucleoprotein C

chr6_+_125552948 0.687 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Vwf


Von Willebrand factor homolog


chrX_+_106920618 0.683 ENSMUST00000060576.7
Lpar4
lysophosphatidic acid receptor 4
chr5_+_138116903 0.668 ENSMUST00000062350.8
ENSMUST00000110961.2
ENSMUST00000080732.3
ENSMUST00000110960.2
ENSMUST00000142185.1
ENSMUST00000136425.1
ENSMUST00000110959.1
Zscan21






zinc finger and SCAN domain containing 21






chr4_+_62525369 0.637 ENSMUST00000062145.1
4933430I17Rik
RIKEN cDNA 4933430I17 gene
chr1_-_161070613 0.636 ENSMUST00000035430.3
Dars2
aspartyl-tRNA synthetase 2 (mitochondrial)
chr8_-_112011320 0.635 ENSMUST00000034426.6
Kars
lysyl-tRNA synthetase
chr2_-_29787622 0.616 ENSMUST00000177467.1
ENSMUST00000113807.3
Trub2

TruB pseudouridine (psi) synthase homolog 2 (E. coli)

chr9_-_39603635 0.615 ENSMUST00000119722.1
AW551984
expressed sequence AW551984
chr3_+_53488677 0.610 ENSMUST00000029307.3
Stoml3
stomatin (Epb7.2)-like 3
chr2_+_110597298 0.608 ENSMUST00000045972.6
ENSMUST00000111026.2
Slc5a12

solute carrier family 5 (sodium/glucose cotransporter), member 12

chr11_-_109611417 0.605 ENSMUST00000103060.3
ENSMUST00000047186.3
ENSMUST00000106689.1
Wipi1


WD repeat domain, phosphoinositide interacting 1


chr8_-_112011266 0.558 ENSMUST00000164470.1
ENSMUST00000093120.5
Kars

lysyl-tRNA synthetase

chr11_+_114851142 0.556 ENSMUST00000133245.1
ENSMUST00000122967.2
Gprc5c

G protein-coupled receptor, family C, group 5, member C

chr11_+_60537978 0.550 ENSMUST00000044250.3
Alkbh5
alkB, alkylation repair homolog 5 (E. coli)
chrX_+_9885622 0.512 ENSMUST00000067529.2
ENSMUST00000086165.3
Sytl5

synaptotagmin-like 5

chr6_+_63255971 0.504 ENSMUST00000159561.1
ENSMUST00000095852.3
Grid2

glutamate receptor, ionotropic, delta 2

chr3_+_103739366 0.494 ENSMUST00000106852.1
Gm10964
predicted gene 10964
chr6_-_54566484 0.482 ENSMUST00000019268.4
Scrn1
secernin 1
chr5_-_3647806 0.474 ENSMUST00000119783.1
ENSMUST00000007559.8
Gatad1

GATA zinc finger domain containing 1

chr2_+_76650264 0.472 ENSMUST00000099986.2
Dfnb59
deafness, autosomal recessive 59 (human)
chr15_+_98571004 0.469 ENSMUST00000023728.6
4930415O20Rik
RIKEN cDNA 4930415O20 gene
chr4_+_103143052 0.445 ENSMUST00000106855.1
Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr4_+_95557494 0.438 ENSMUST00000079223.4
ENSMUST00000177394.1
Fggy

FGGY carbohydrate kinase domain containing

chr2_-_164389095 0.436 ENSMUST00000167427.1
Slpi
secretory leukocyte peptidase inhibitor
chr12_-_80643799 0.431 ENSMUST00000166931.1
Erh
enhancer of rudimentary homolog (Drosophila)
chr6_-_122340499 0.429 ENSMUST00000160843.1
Phc1
polyhomeotic-like 1 (Drosophila)
chr7_+_19368498 0.421 ENSMUST00000132655.1
Ppp1r13l
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chrX_+_107255878 0.403 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
Gpr174


G protein-coupled receptor 174


chr11_+_58171648 0.399 ENSMUST00000020820.1
Mrpl22
mitochondrial ribosomal protein L22
chr9_-_13818665 0.395 ENSMUST00000150893.1
ENSMUST00000124883.1
Cep57

centrosomal protein 57

chr1_+_110099295 0.385 ENSMUST00000134301.1
Cdh7
cadherin 7, type 2
chr3_+_88297147 0.381 ENSMUST00000164166.1
ENSMUST00000168062.1
Cct3

chaperonin containing Tcp1, subunit 3 (gamma)

chr14_-_104522615 0.376 ENSMUST00000022716.2
Rnf219
ring finger protein 219
chr14_-_100149764 0.371 ENSMUST00000097079.4
Klf12
Kruppel-like factor 12
chr7_+_100159241 0.361 ENSMUST00000032967.3
Lipt2
lipoyl(octanoyl) transferase 2 (putative)
chr4_-_14621669 0.358 ENSMUST00000143105.1
Slc26a7
solute carrier family 26, member 7
chrM_+_8600 0.349 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr3_+_88297115 0.347 ENSMUST00000001452.7
Cct3
chaperonin containing Tcp1, subunit 3 (gamma)
chr5_-_63968867 0.326 ENSMUST00000154169.1
Rell1
RELT-like 1
chr10_-_33995054 0.305 ENSMUST00000164429.1
Gm17567
predicted gene, 17567
chr2_+_69897255 0.286 ENSMUST00000131553.1
Ubr3
ubiquitin protein ligase E3 component n-recognin 3
chr2_-_160619971 0.283 ENSMUST00000109473.1
Gm14221
predicted gene 14221
chr5_-_100416115 0.275 ENSMUST00000182886.1
ENSMUST00000094578.4
Sec31a

Sec31 homolog A (S. cerevisiae)

chr2_-_91649785 0.261 ENSMUST00000111333.1
Zfp408
zinc finger protein 408
chr11_-_99230998 0.259 ENSMUST00000103133.3
Smarce1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr5_-_88675190 0.252 ENSMUST00000133532.1
ENSMUST00000150438.1
Grsf1

G-rich RNA sequence binding factor 1

chr9_+_94669876 0.237 ENSMUST00000033463.9
Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr16_-_87495704 0.233 ENSMUST00000176750.1
ENSMUST00000175977.1
Cct8

chaperonin containing Tcp1, subunit 8 (theta)

chr6_-_30693676 0.232 ENSMUST00000169422.1
ENSMUST00000115131.1
ENSMUST00000115130.2
ENSMUST00000031810.8
Cep41



centrosomal protein 41



chr7_+_38183217 0.225 ENSMUST00000165308.1
1600014C10Rik
RIKEN cDNA 1600014C10 gene
chr10_-_76110956 0.223 ENSMUST00000120757.1
Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr17_-_47502276 0.218 ENSMUST00000067103.2
Taf8
TAF8 RNA polymerase II, TATA box binding protein (TBP)-associated factorq
chr4_+_100478806 0.217 ENSMUST00000133493.2
ENSMUST00000092730.3
ENSMUST00000106979.3
Ube2u


ubiquitin-conjugating enzyme E2U (putative)


chr9_-_50659780 0.191 ENSMUST00000034567.3
Dlat
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr9_+_37208291 0.160 ENSMUST00000034632.8
Tmem218
transmembrane protein 218
chr13_-_97747373 0.159 ENSMUST00000123535.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr7_+_101896817 0.157 ENSMUST00000143835.1
Anapc15
anaphase prompoting complex C subunit 15
chr1_-_172027269 0.146 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr12_+_80644212 0.136 ENSMUST00000085245.5
Slc39a9
solute carrier family 39 (zinc transporter), member 9
chr1_-_152625212 0.118 ENSMUST00000027760.7
Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr6_-_136875794 0.114 ENSMUST00000032342.1
Mgp
matrix Gla protein
chr8_-_34965631 0.107 ENSMUST00000033929.4
Tnks
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr6_+_47920476 0.103 ENSMUST00000009411.8
Zfp212
Zinc finger protein 212
chr6_+_37870786 0.081 ENSMUST00000120428.1
ENSMUST00000031859.7
Trim24

tripartite motif-containing 24

chr4_+_154964117 0.080 ENSMUST00000030931.4
ENSMUST00000070953.4
Pank4

pantothenate kinase 4

chr19_-_32196393 0.069 ENSMUST00000151822.1
Sgms1
sphingomyelin synthase 1
chr13_-_97747399 0.061 ENSMUST00000144993.1
5330416C01Rik
RIKEN cDNA 5330416C01 gene
chr9_+_27299205 0.037 ENSMUST00000115247.1
ENSMUST00000133213.1
Igsf9b

immunoglobulin superfamily, member 9B

chr16_+_52031549 0.031 ENSMUST00000114471.1
Cblb
Casitas B-lineage lymphoma b
chr9_+_121950988 0.030 ENSMUST00000043011.7
Fam198a
family with sequence similarity 198, member A
chrX_-_157415286 0.024 ENSMUST00000079945.4
ENSMUST00000138396.1
Phex

phosphate regulating gene with homologies to endopeptidases on the X chromosome (hypophosphatemia, vitamin D resistant rickets)

chr4_+_95967205 0.015 ENSMUST00000030306.7
Hook1
hook homolog 1 (Drosophila)
chr9_+_72958785 0.008 ENSMUST00000098567.2
ENSMUST00000034734.8
Dyx1c1

dyslexia susceptibility 1 candidate 1 homolog (human)

chr7_-_44236098 0.001 ENSMUST00000037220.4
1700028J19Rik
RIKEN cDNA 1700028J19 gene

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
3.2 9.6 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
2.6 10.5 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
2.0 6.0 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
1.4 4.2 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.9 2.8 GO:0006059 hexitol metabolic process(GO:0006059) alditol biosynthetic process(GO:0019401)
0.8 2.5 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.8 15.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.6 1.9 GO:1904395 regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904393) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.6 3.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.6 2.5 GO:0010700 negative regulation of norepinephrine secretion(GO:0010700)
0.6 4.8 GO:0048625 myoblast fate commitment(GO:0048625)
0.5 1.6 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.5 1.6 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.5 1.8 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.4 1.2 GO:0015960 diadenosine polyphosphate biosynthetic process(GO:0015960) diadenosine tetraphosphate metabolic process(GO:0015965) diadenosine tetraphosphate biosynthetic process(GO:0015966)
0.4 1.2 GO:0009193 pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) UDP metabolic process(GO:0046048)
0.3 1.0 GO:0050929 corticospinal neuron axon guidance through spinal cord(GO:0021972) positive regulation of negative chemotaxis(GO:0050924) induction of negative chemotaxis(GO:0050929) negative regulation of mononuclear cell migration(GO:0071676) negative regulation of retinal ganglion cell axon guidance(GO:0090260)
0.3 1.0 GO:0008228 opsonization(GO:0008228) modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.3 0.9 GO:0010757 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) negative regulation of plasminogen activation(GO:0010757) regulation of vascular wound healing(GO:0061043) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.3 0.9 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.3 1.5 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.3 1.4 GO:0015819 lysine transport(GO:0015819)
0.3 3.4 GO:0031017 exocrine pancreas development(GO:0031017)
0.3 0.8 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
0.3 2.3 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.2 0.4 GO:0009106 lipoate metabolic process(GO:0009106)
0.2 8.4 GO:0051693 actin filament capping(GO:0051693)
0.2 0.7 GO:0090365 regulation of mRNA modification(GO:0090365)
0.2 2.7 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.2 2.1 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.1 1.0 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.1 0.6 GO:0035553 oxidative RNA demethylation(GO:0035513) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.9 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 2.4 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.1 0.6 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 2.7 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.1 1.2 GO:0006670 sphingosine metabolic process(GO:0006670)
0.1 4.1 GO:0030901 midbrain development(GO:0030901)
0.1 1.0 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.1 5.1 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.1 1.1 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.1 GO:0061341 non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 1.7 GO:0006907 pinocytosis(GO:0006907)
0.1 1.2 GO:0097352 autophagosome maturation(GO:0097352)
0.1 0.6 GO:0048199 vesicle targeting, to, from or within Golgi(GO:0048199)
0.1 1.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 3.4 GO:0031338 regulation of vesicle fusion(GO:0031338)
0.0 0.8 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.4 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.8 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.4 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:1904742 protein poly-ADP-ribosylation(GO:0070212) regulation of telomeric DNA binding(GO:1904742)
0.0 1.1 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.0 GO:0031365 N-terminal protein amino acid modification(GO:0031365)
0.0 0.6 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.4 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 2.1 GO:0007601 visual perception(GO:0007601)
0.0 0.4 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 2.6 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.5 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0 1.1 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.4 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.7 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 1.2 GO:0000725 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.0 0.4 GO:0006221 pyrimidine nucleotide biosynthetic process(GO:0006221)
0.0 2.2 GO:0006909 phagocytosis(GO:0006909)
0.0 1.1 GO:0003073 regulation of systemic arterial blood pressure(GO:0003073)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.6 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.4 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.7 GO:0030168 platelet activation(GO:0030168)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.8 GO:0097454 Schwann cell microvillus(GO:0097454)
0.5 4.8 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.5 2.6 GO:0008623 CHRAC(GO:0008623)
0.2 1.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 1.8 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 0.9 GO:0042583 chromaffin granule(GO:0042583)
0.1 0.7 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 1.9 GO:0016600 flotillin complex(GO:0016600)
0.1 0.9 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 1.2 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.9 GO:0060091 kinocilium(GO:0060091)
0.1 15.4 GO:0000792 heterochromatin(GO:0000792)
0.1 3.4 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 5.1 GO:0016459 myosin complex(GO:0016459)
0.1 1.6 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 1.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 1.6 GO:0001891 phagocytic cup(GO:0001891)
0.1 4.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.7 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 10.5 GO:0030426 growth cone(GO:0030426)
0.0 2.2 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.7 GO:0045120 pronucleus(GO:0045120)
0.0 0.4 GO:0034709 methylosome(GO:0034709)
0.0 1.1 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.8 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.6 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 1.2 GO:0030496 midbody(GO:0030496)
0.0 1.2 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 5.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.7 GO:0009925 basal plasma membrane(GO:0009925)
0.0 1.6 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 1.1 GO:0030315 T-tubule(GO:0030315)
0.0 4.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 0.5 GO:0098878 ionotropic glutamate receptor complex(GO:0008328) neurotransmitter receptor complex(GO:0098878)
0.0 0.4 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 9.6 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.7 2.1 GO:0005118 sevenless binding(GO:0005118)
0.4 2.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.3 3.4 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.3 2.5 GO:0031432 titin binding(GO:0031432)
0.3 2.3 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.3 2.2 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.3 0.8 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.2 1.6 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 4.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.2 1.4 GO:0015189 L-ornithine transmembrane transporter activity(GO:0000064) arginine transmembrane transporter activity(GO:0015181) L-lysine transmembrane transporter activity(GO:0015189)
0.2 4.8 GO:0045295 gamma-catenin binding(GO:0045295)
0.2 1.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 1.0 GO:0001849 complement component C1q binding(GO:0001849)
0.2 1.2 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.2 0.9 GO:0034604 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.2 1.1 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.2 1.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 2.4 GO:0016594 glycine binding(GO:0016594)
0.1 1.0 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.6 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.9 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled adenosine receptor activity(GO:0001609) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.9 GO:0070191 methionine-R-sulfoxide reductase activity(GO:0070191)
0.1 2.7 GO:0070410 co-SMAD binding(GO:0070410)
0.1 2.8 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 1.5 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.1 5.1 GO:0030507 spectrin binding(GO:0030507)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.9 GO:0034185 apolipoprotein binding(GO:0034185)
0.1 0.7 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 2.7 GO:0005109 frizzled binding(GO:0005109)
0.1 21.5 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 0.7 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.1 0.8 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.1 1.2 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.1 8.6 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.1 0.6 GO:0034951 pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011)
0.0 1.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 1.6 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.8 GO:0001103 RNA polymerase II repressing transcription factor binding(GO:0001103)
0.0 1.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.9 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 1.8 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812)
0.0 1.6 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.5 GO:0016805 dipeptidase activity(GO:0016805)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.2 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 1.4 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 15.1 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.0 0.4 GO:0042556 cobinamide kinase activity(GO:0008819) phytol kinase activity(GO:0010276) phenol kinase activity(GO:0018720) cyclin-dependent protein kinase activating kinase regulator activity(GO:0019914) inositol tetrakisphosphate 2-kinase activity(GO:0032942) heptose 7-phosphate kinase activity(GO:0033785) aminoglycoside phosphotransferase activity(GO:0034071) eukaryotic elongation factor-2 kinase regulator activity(GO:0042556) eukaryotic elongation factor-2 kinase activator activity(GO:0042557) LPPG:FO 2-phospho-L-lactate transferase activity(GO:0043743) cytidine kinase activity(GO:0043771) glycerate 2-kinase activity(GO:0043798) (S)-lactate 2-kinase activity(GO:0043841) phosphoserine:homoserine phosphotransferase activity(GO:0043899) L-seryl-tRNA(Sec) kinase activity(GO:0043915) phosphocholine transferase activity(GO:0044605) GTP-dependent polynucleotide kinase activity(GO:0051735) farnesol kinase activity(GO:0052668) CTP:2-trans,-6-trans-farnesol kinase activity(GO:0052669) geraniol kinase activity(GO:0052670) geranylgeraniol kinase activity(GO:0052671) CTP:geranylgeraniol kinase activity(GO:0052672) prenol kinase activity(GO:0052673) 1-phosphatidylinositol-5-kinase activity(GO:0052810) 1-phosphatidylinositol-3-phosphate 4-kinase activity(GO:0052811) phosphatidylinositol-3,4-bisphosphate 5-kinase activity(GO:0052812) inositol-3,4,6-trisphosphate 1-kinase activity(GO:0052835) inositol 5-diphosphate pentakisphosphate 5-kinase activity(GO:0052836) inositol diphosphate tetrakisphosphate kinase activity(GO:0052839)
0.0 0.5 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 3.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.0 0.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.4 GO:0016415 octanoyltransferase activity(GO:0016415)