Motif ID: Hdx

Z-value: 6.534


Transcription factors associated with Hdx:

Gene SymbolEntrez IDGene Name
Hdx ENSMUSG00000034551.6 Hdx

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hdxmm10_v2_chrX_-_111697069_111697127-0.019.6e-01Click!


Activity profile for motif Hdx.

activity profile for motif Hdx


Sorted Z-values histogram for motif Hdx

Sorted Z-values for motif Hdx



Network of associatons between targets according to the STRING database.



First level regulatory network of Hdx

PNG image of the network

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Top targets:


Showing 1 to 20 of 102 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_3017408 409.252 ENSMUST00000099049.3
 Gm10719
predicted gene 10719
chr9_+_3015654 361.440 ENSMUST00000099050.3
 Gm10720
predicted gene 10720
chr9_+_3023547 336.190 ENSMUST00000099046.3
 Gm10718
predicted gene 10718
chr9_+_3005125 319.843 ENSMUST00000179881.1
 Gm11168
predicted gene 11168
chr9_+_3000922 293.692 ENSMUST00000151376.2
 Gm10722
predicted gene 10722
chr9_+_3034599 289.343 ENSMUST00000178641.1
 Gm17535
predicted gene, 17535
chr9_+_3027439 266.874 ENSMUST00000177875.1
ENSMUST00000179982.1
 Gm10717

predicted gene 10717

chr9_+_3025417 252.846 ENSMUST00000075573.6
 Gm10717
predicted gene 10717
chr14_-_19418930 237.475 ENSMUST00000177817.1
 Gm21738
predicted gene, 21738
chr9_+_3018753 211.316 ENSMUST00000179272.1
 Gm10719
predicted gene 10719
chr9_+_3004457 194.329 ENSMUST00000178348.1
 Gm11168
predicted gene 11168
chr9_+_3036877 176.026 ENSMUST00000155807.2
 Gm10715
predicted gene 10715
chr9_+_3037111 165.256 ENSMUST00000177969.1
 Gm10715
predicted gene 10715
chr9_+_3013140 159.809 ENSMUST00000143083.2
 Gm10721
predicted gene 10721
chr2_-_98667264 119.778 ENSMUST00000099683.1
 Gm10800
predicted gene 10800
chr6_-_23248264 65.666 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr13_+_24327415 24.943 ENSMUST00000167746.1
 Cmah
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr16_-_26989974 23.167 ENSMUST00000089832.4
 Gmnc
geminin coiled-coil domain containing
chr3_-_154330543 19.015 ENSMUST00000184966.1
ENSMUST00000177846.2
 Lhx8

LIM homeobox protein 8

chrX_-_143827391 12.953 ENSMUST00000087316.5
 Capn6
calpain 6

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2566.2 GO:0008150 biological_process(GO:0008150)
10.9 65.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
8.3 24.9 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.7 23.2 GO:0006270 DNA replication initiation(GO:0006270)
0.4 19.0 GO:0021884 forebrain neuron development(GO:0021884)
2.1 10.6 GO:0019659 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
3.1 9.2 GO:0045410 positive regulation of interleukin-6 biosynthetic process(GO:0045410)
0.4 9.2 GO:0097352 autophagosome maturation(GO:0097352)
0.4 9.0 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
1.8 8.9 GO:0007171 activation of transmembrane receptor protein tyrosine kinase activity(GO:0007171) prolactin signaling pathway(GO:0038161)
0.2 8.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.4 7.5 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
2.1 6.3 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
1.2 5.9 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
1.9 5.6 GO:2000501 natural killer cell chemotaxis(GO:0035747) negative regulation of lymphocyte migration(GO:2000402) regulation of natural killer cell chemotaxis(GO:2000501)
0.2 5.0 GO:0034063 stress granule assembly(GO:0034063)
0.2 5.0 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
1.5 4.5 GO:0061526 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) musculoskeletal movement, spinal reflex action(GO:0050883) acetylcholine secretion(GO:0061526)
0.7 4.1 GO:0006344 maintenance of chromatin silencing(GO:0006344)
1.0 3.8 GO:0039536 negative regulation of RIG-I signaling pathway(GO:0039536)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2727.8 GO:0005575 cellular_component(GO:0005575)
3.2 19.0 GO:0001674 female germ cell nucleus(GO:0001674)
0.2 13.0 GO:0005876 spindle microtubule(GO:0005876)
0.8 10.6 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 9.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.4 6.3 GO:0042101 T cell receptor complex(GO:0042101)
0.4 4.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.2 4.1 GO:0071564 npBAF complex(GO:0071564)
0.2 3.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.8 2.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.5 1.9 GO:0060187 cell pole(GO:0060187)
0.4 1.6 GO:0032021 NELF complex(GO:0032021)
0.2 1.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 1.1 GO:0005638 lamin filament(GO:0005638)
0.2 0.9 GO:0001651 dense fibrillar component(GO:0001651)
0.2 0.7 GO:1990130 Iml1 complex(GO:1990130)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 26 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 2632.9 GO:0003674 molecular_function(GO:0003674)
0.2 36.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
8.3 24.9 GO:0016716 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, another compound as one donor, and incorporation of one atom of oxygen(GO:0016716)
0.7 13.0 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
2.6 10.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.7 9.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.3 9.0 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.3 8.9 GO:0017046 peptide hormone binding(GO:0017046)
0.5 7.5 GO:0070403 NAD+ binding(GO:0070403)
2.1 6.3 GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
1.4 5.6 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.3 5.5 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.2 5.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.9 4.5 GO:0070330 aromatase activity(GO:0070330)
0.3 4.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.5 4.1 GO:0008193 tRNA guanylyltransferase activity(GO:0008193)
0.2 3.8 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
1.0 2.9 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 2.7 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 2.6 GO:0008097 5S rRNA binding(GO:0008097)