Motif ID: Hes5_Hes7
Z-value: 1.214


Transcription factors associated with Hes5_Hes7:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hes5 | ENSMUSG00000048001.7 | Hes5 |
Hes7 | ENSMUSG00000023781.2 | Hes7 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hes7 | mm10_v2_chr11_+_69120404_69120404 | -0.38 | 2.7e-03 | Click! |
Hes5 | mm10_v2_chr4_+_154960915_154960930 | 0.30 | 2.3e-02 | Click! |
Top targets:
Showing 1 to 20 of 101 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 58 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
10.1 | 91.1 | GO:0045719 | negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874) |
1.6 | 21.9 | GO:0035269 | protein O-linked mannosylation(GO:0035269) |
4.7 | 14.2 | GO:0021759 | globus pallidus development(GO:0021759) |
0.3 | 12.2 | GO:0045746 | negative regulation of Notch signaling pathway(GO:0045746) |
3.7 | 11.1 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) musculoskeletal movement, spinal reflex action(GO:0050883) olfactory pit development(GO:0060166) |
0.1 | 10.9 | GO:0030177 | positive regulation of Wnt signaling pathway(GO:0030177) |
1.4 | 9.8 | GO:0043951 | negative regulation of cAMP-mediated signaling(GO:0043951) |
0.1 | 8.9 | GO:0030512 | negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512) negative regulation of cellular response to transforming growth factor beta stimulus(GO:1903845) |
0.9 | 7.5 | GO:0038031 | non-canonical Wnt signaling pathway via JNK cascade(GO:0038031) |
1.0 | 6.0 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
0.5 | 5.7 | GO:0000244 | spliceosomal tri-snRNP complex assembly(GO:0000244) |
0.2 | 5.7 | GO:0030513 | positive regulation of BMP signaling pathway(GO:0030513) |
0.0 | 5.1 | GO:1901657 | glycosyl compound metabolic process(GO:1901657) |
0.6 | 4.5 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
0.4 | 4.5 | GO:1990403 | embryonic brain development(GO:1990403) |
1.4 | 4.3 | GO:0010814 | substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959) |
1.4 | 4.2 | GO:0015772 | disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772) |
0.2 | 4.1 | GO:0008340 | determination of adult lifespan(GO:0008340) |
0.2 | 3.9 | GO:0043567 | regulation of insulin-like growth factor receptor signaling pathway(GO:0043567) |
0.2 | 3.9 | GO:0035115 | negative regulation of chondrocyte differentiation(GO:0032331) embryonic forelimb morphogenesis(GO:0035115) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 35 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.0 | 78.4 | GO:0005829 | cytosol(GO:0005829) |
0.0 | 13.4 | GO:0005667 | transcription factor complex(GO:0005667) |
0.1 | 12.3 | GO:0009897 | external side of plasma membrane(GO:0009897) |
0.1 | 11.1 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
0.1 | 6.3 | GO:0005657 | replication fork(GO:0005657) |
0.2 | 5.7 | GO:0046540 | U4/U6 x U5 tri-snRNP complex(GO:0046540) |
0.0 | 5.1 | GO:0005903 | brush border(GO:0005903) |
0.0 | 4.5 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.9 | 4.3 | GO:0033093 | Weibel-Palade body(GO:0033093) |
0.0 | 3.9 | GO:0016324 | apical plasma membrane(GO:0016324) |
0.0 | 3.9 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.4 | 3.4 | GO:0046581 | intercellular canaliculus(GO:0046581) |
0.3 | 3.4 | GO:0043219 | catenin complex(GO:0016342) lateral loop(GO:0043219) |
0.0 | 2.9 | GO:0005581 | collagen trimer(GO:0005581) |
0.1 | 2.5 | GO:0005652 | nuclear lamina(GO:0005652) |
0.0 | 2.4 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
0.3 | 2.2 | GO:0005890 | sodium:potassium-exchanging ATPase complex(GO:0005890) |
0.2 | 1.8 | GO:0070545 | PeBoW complex(GO:0070545) |
0.0 | 1.7 | GO:0005840 | ribosome(GO:0005840) |
0.1 | 1.6 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 42 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
4.1 | 91.1 | GO:0001784 | phosphotyrosine binding(GO:0001784) |
4.4 | 21.9 | GO:0018121 | imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102) |
1.2 | 14.2 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
0.3 | 11.7 | GO:0043425 | bHLH transcription factor binding(GO:0043425) |
0.1 | 10.0 | GO:0001085 | RNA polymerase II transcription factor binding(GO:0001085) |
0.2 | 9.8 | GO:0061631 | ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650) |
0.3 | 7.5 | GO:0042813 | Wnt-activated receptor activity(GO:0042813) |
2.0 | 6.0 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
0.2 | 5.1 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
0.1 | 4.9 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
0.6 | 4.5 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
1.4 | 4.2 | GO:0008515 | sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157) |
0.5 | 3.9 | GO:0031995 | insulin-like growth factor II binding(GO:0031995) |
0.1 | 3.9 | GO:0005109 | frizzled binding(GO:0005109) |
0.0 | 3.9 | GO:0005096 | GTPase activator activity(GO:0005096) |
0.3 | 3.4 | GO:0045294 | alpha-catenin binding(GO:0045294) |
0.0 | 3.4 | GO:0008022 | protein C-terminus binding(GO:0008022) |
0.3 | 2.9 | GO:0017147 | Wnt-protein binding(GO:0017147) |
0.0 | 2.7 | GO:0035064 | methylated histone binding(GO:0035064) |
0.2 | 2.4 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |