Motif ID: Hey1_Myc_Mxi1

Z-value: 1.139

Transcription factors associated with Hey1_Myc_Mxi1:

Gene SymbolEntrez IDGene Name
Hey1 ENSMUSG00000040289.3 Hey1
Mxi1 ENSMUSG00000025025.7 Mxi1
Myc ENSMUSG00000022346.8 Myc

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mxi1mm10_v2_chr19_+_53329413_53329478-0.853.2e-17Click!
Mycmm10_v2_chr15_+_61987034_61987059-0.401.6e-03Click!
Hey1mm10_v2_chr3_-_8667033_86670460.274.1e-02Click!


Activity profile for motif Hey1_Myc_Mxi1.

activity profile for motif Hey1_Myc_Mxi1


Sorted Z-values histogram for motif Hey1_Myc_Mxi1

Sorted Z-values for motif Hey1_Myc_Mxi1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hey1_Myc_Mxi1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_43239816 13.838 ENSMUST00000034512.5
 Oaf
OAF homolog (Drosophila)
chr19_+_56874249 11.707 ENSMUST00000026068.7
 Vwa2
von Willebrand factor A domain containing 2
chr10_+_127063599 11.459 ENSMUST00000120226.1
ENSMUST00000133115.1
 Cdk4

cyclin-dependent kinase 4

chr2_-_92370999 11.021 ENSMUST00000176810.1
ENSMUST00000090582.4
 Gyltl1b

glycosyltransferase-like 1B

chr3_-_95882193 10.480 ENSMUST00000159863.1
ENSMUST00000159739.1
ENSMUST00000036418.3
 Gm129


predicted gene 129


chr10_+_127063527 10.432 ENSMUST00000006911.5
 Cdk4
cyclin-dependent kinase 4
chr5_-_137314175 10.348 ENSMUST00000024119.9
 Trip6
thyroid hormone receptor interactor 6
chrX_+_73639414 9.982 ENSMUST00000019701.8
 Dusp9
dual specificity phosphatase 9
chr3_+_107595031 9.521 ENSMUST00000014747.1
 Alx3
aristaless-like homeobox 3
chr3_-_95882031 9.472 ENSMUST00000161994.1
 Gm129
predicted gene 129
chr14_-_20181773 9.381 ENSMUST00000024011.8
 Kcnk5
potassium channel, subfamily K, member 5
chr12_+_109459843 9.341 ENSMUST00000173812.1
 Dlk1
delta-like 1 homolog (Drosophila)
chr4_-_11386757 8.983 ENSMUST00000108313.1
ENSMUST00000108311.2
 Esrp1

epithelial splicing regulatory protein 1

chr2_-_92371039 8.978 ENSMUST00000068586.6
 Gyltl1b
glycosyltransferase-like 1B
chr10_+_22158566 8.739 ENSMUST00000181645.1
ENSMUST00000105522.2
 Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr15_-_43170809 8.550 ENSMUST00000063492.6
 Rspo2
R-spondin 2 homolog (Xenopus laevis)
chr3_-_90052463 8.508 ENSMUST00000029553.9
ENSMUST00000064639.8
ENSMUST00000090908.6
 Ubap2l


ubiquitin associated protein 2-like


chrX_-_141725181 8.215 ENSMUST00000067841.7
 Irs4
insulin receptor substrate 4
chr12_+_17544873 8.208 ENSMUST00000171737.1
 Odc1
ornithine decarboxylase, structural 1
chr11_-_12026237 8.120 ENSMUST00000150972.1
 Grb10
growth factor receptor bound protein 10

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 516 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 27.7 GO:0035269 protein O-linked mannosylation(GO:0035269)
5.5 21.9 GO:0010288 response to lead ion(GO:0010288)
0.2 20.7 GO:0007601 visual perception(GO:0007601)
0.5 19.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
1.7 16.6 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
3.2 16.0 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
1.7 15.3 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
2.5 15.1 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.4 13.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.6 13.0 GO:0006907 pinocytosis(GO:0006907)
2.1 12.9 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.2 12.6 GO:0006405 RNA export from nucleus(GO:0006405)
4.1 12.4 GO:0090194 negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194)
0.3 12.0 GO:0006446 regulation of translational initiation(GO:0006446)
3.9 11.7 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
1.7 11.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
2.3 11.5 GO:0018002 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
1.2 11.2 GO:0010587 miRNA catabolic process(GO:0010587)
3.6 10.9 GO:0042822 vitamin B6 metabolic process(GO:0042816) pyridoxal phosphate metabolic process(GO:0042822) pyridoxal phosphate biosynthetic process(GO:0042823)
0.7 10.9 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 234 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 96.2 GO:0070062 extracellular exosome(GO:0070062)
0.1 40.2 GO:0005925 focal adhesion(GO:0005925)
0.7 32.9 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 27.8 GO:0005730 nucleolus(GO:0005730)
0.5 23.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 18.9 GO:0005604 basement membrane(GO:0005604)
1.2 17.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 16.5 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 16.3 GO:0005576 extracellular region(GO:0005576)
1.5 14.6 GO:0005642 annulate lamellae(GO:0005642)
1.8 12.9 GO:0097422 tubular endosome(GO:0097422)
0.6 12.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 12.3 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
1.5 12.0 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.1 11.3 GO:0034399 nuclear periphery(GO:0034399)
0.7 11.0 GO:0034719 SMN-Sm protein complex(GO:0034719)
2.2 10.8 GO:0044611 nuclear pore inner ring(GO:0044611)
1.3 10.8 GO:0031415 NatA complex(GO:0031415)
0.1 10.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.4 9.9 GO:0030687 preribosome, large subunit precursor(GO:0030687)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 355 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 36.8 GO:0044822 poly(A) RNA binding(GO:0044822)
5.6 28.0 GO:0018121 imidazoleglycerol-phosphate synthase activity(GO:0000107) NAD(P)-cysteine ADP-ribosyltransferase activity(GO:0018071) NAD(P)-asparagine ADP-ribosyltransferase activity(GO:0018121) NAD(P)-serine ADP-ribosyltransferase activity(GO:0018127) 7-cyano-7-deazaguanine tRNA-ribosyltransferase activity(GO:0043867) purine deoxyribosyltransferase activity(GO:0044102)
0.5 25.0 GO:0016831 carboxy-lyase activity(GO:0016831)
0.5 19.7 GO:0030332 cyclin binding(GO:0030332)
1.9 18.9 GO:0070700 BMP receptor binding(GO:0070700)
0.1 16.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.7 15.3 GO:0001784 phosphotyrosine binding(GO:0001784)
2.5 15.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
1.1 14.6 GO:0017070 U6 snRNA binding(GO:0017070)
1.1 13.6 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 13.6 GO:0004402 histone acetyltransferase activity(GO:0004402)
4.5 13.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.3 13.2 GO:0008536 Ran GTPase binding(GO:0008536)
4.2 12.7 GO:0005118 sevenless binding(GO:0005118)
0.3 12.7 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.6 12.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.4 12.2 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 11.8 GO:0016428 tRNA (cytosine) methyltransferase activity(GO:0016427) tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
1.0 11.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 11.6 GO:0003725 double-stranded RNA binding(GO:0003725)