Motif ID: Hic1

Z-value: 1.787


Transcription factors associated with Hic1:

Gene SymbolEntrez IDGene Name
Hic1 ENSMUSG00000043099.4 Hic1



Activity profile for motif Hic1.

activity profile for motif Hic1


Sorted Z-values histogram for motif Hic1

Sorted Z-values for motif Hic1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hic1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr8_-_84800024 21.261 ENSMUST00000126806.1
ENSMUST00000076715.6
 Nfix

nuclear factor I/X

chr8_-_84800344 13.848 ENSMUST00000099070.3
 Nfix
nuclear factor I/X
chr9_+_45430293 9.861 ENSMUST00000034592.8
 Dscaml1
Down syndrome cell adhesion molecule like 1
chr11_-_6065538 8.799 ENSMUST00000101585.3
ENSMUST00000066431.7
ENSMUST00000109815.2
ENSMUST00000109812.2
ENSMUST00000101586.2
ENSMUST00000093355.5
ENSMUST00000019133.4
 Camk2b






calcium/calmodulin-dependent protein kinase II, beta






chr3_-_88000350 8.627 ENSMUST00000090971.5
 Bcan
brevican
chr5_-_62766153 7.925 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr12_+_73997749 7.789 ENSMUST00000110451.2
 Syt16
synaptotagmin XVI
chr4_-_46991842 7.654 ENSMUST00000107749.2
 Gabbr2
gamma-aminobutyric acid (GABA) B receptor, 2
chr6_-_32588192 7.646 ENSMUST00000115096.2
 Plxna4
plexin A4
chr13_+_109903089 7.592 ENSMUST00000120664.1
 Pde4d
phosphodiesterase 4D, cAMP specific
chr7_+_130936172 7.544 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr11_-_32222233 7.385 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
 Rhbdf1


rhomboid family 1 (Drosophila)


chr9_+_26733845 7.128 ENSMUST00000115269.2
 B3gat1
beta-1,3-glucuronyltransferase 1 (glucuronosyltransferase P)
chr14_-_30353468 7.101 ENSMUST00000112249.1
 Cacna1d
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr17_+_26715644 7.095 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
 Crebrf



CREB3 regulatory factor



chr6_+_90550789 6.710 ENSMUST00000130418.1
ENSMUST00000032175.8
 Aldh1l1

aldehyde dehydrogenase 1 family, member L1

chr4_-_139092958 6.650 ENSMUST00000042844.6
 Nbl1
neuroblastoma, suppression of tumorigenicity 1
chr7_+_46396439 6.379 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr2_+_71117923 6.219 ENSMUST00000028403.2
 Cybrd1
cytochrome b reductase 1
chr11_+_63131512 6.140 ENSMUST00000018361.3
 Pmp22
peripheral myelin protein 22

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 462 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.6 41.8 GO:0021683 cerebellar granular layer morphogenesis(GO:0021683)
1.2 24.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
4.5 13.6 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430) activation of meiosis involved in egg activation(GO:0060466)
0.1 13.4 GO:0008654 phospholipid biosynthetic process(GO:0008654)
0.5 12.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
3.9 11.7 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
0.6 10.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.8 10.3 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 10.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.6 9.0 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
1.1 8.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.1 8.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.2 8.7 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
1.0 7.9 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.1 7.9 GO:0006906 vesicle fusion(GO:0006906)
1.9 7.6 GO:0021564 glossopharyngeal nerve development(GO:0021563) vagus nerve development(GO:0021564)
1.3 7.5 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.2 7.3 GO:0042058 regulation of epidermal growth factor receptor signaling pathway(GO:0042058)
2.4 7.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
1.4 7.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 165 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 179.0 GO:0016021 integral component of membrane(GO:0016021)
0.1 39.0 GO:0005887 integral component of plasma membrane(GO:0005887)
0.1 38.2 GO:0060076 excitatory synapse(GO:0060076)
0.1 35.4 GO:0000139 Golgi membrane(GO:0000139)
0.4 19.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.5 17.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.5 16.4 GO:0051233 spindle midzone(GO:0051233)
0.6 15.2 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 10.8 GO:0031225 anchored component of membrane(GO:0031225)
0.2 10.7 GO:0031901 early endosome membrane(GO:0031901)
0.2 10.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
1.0 9.8 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.4 9.4 GO:0032590 dendrite membrane(GO:0032590)
0.1 8.8 GO:0045211 postsynaptic membrane(GO:0045211)
0.7 8.1 GO:0031091 platelet alpha granule(GO:0031091)
1.5 7.7 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.9 6.9 GO:0033391 chromatoid body(GO:0033391)
0.4 6.9 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 6.9 GO:0045335 phagocytic vesicle(GO:0045335)
1.3 6.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 295 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 31.7 GO:0005096 GTPase activator activity(GO:0005096)
3.3 19.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.8 16.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.6 12.4 GO:0043274 phospholipase binding(GO:0043274)
2.4 12.0 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
3.9 11.7 GO:0098809 nitrite reductase activity(GO:0098809)
0.3 11.1 GO:0030332 cyclin binding(GO:0030332)
0.4 10.7 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.2 10.2 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
0.2 9.7 GO:0045499 chemorepellent activity(GO:0045499)
0.1 9.4 GO:0008017 microtubule binding(GO:0008017)
0.1 9.2 GO:0019210 protein kinase inhibitor activity(GO:0004860) kinase inhibitor activity(GO:0019210)
0.9 8.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.5 8.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.4 8.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
1.2 8.1 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.3 8.1 GO:0017075 syntaxin-1 binding(GO:0017075)
1.3 7.9 GO:0005042 netrin receptor activity(GO:0005042)
0.2 7.9 GO:0070412 R-SMAD binding(GO:0070412)
0.2 7.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)