Motif ID: Hivep1

Z-value: 0.590


Transcription factors associated with Hivep1:

Gene SymbolEntrez IDGene Name
Hivep1 ENSMUSG00000021366.7 Hivep1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hivep1mm10_v2_chr13_+_42052015_420520720.522.2e-05Click!


Activity profile for motif Hivep1.

activity profile for motif Hivep1


Sorted Z-values histogram for motif Hivep1

Sorted Z-values for motif Hivep1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hivep1

PNG image of the network

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Top targets:


Showing 1 to 20 of 151 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_88000350 11.073 ENSMUST00000090971.5
Bcan
brevican
chr15_-_79164477 9.991 ENSMUST00000040019.4
Sox10
SRY-box containing gene 10
chr3_+_117575268 5.735 ENSMUST00000039564.6
4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr10_-_27616895 4.151 ENSMUST00000092639.5
Lama2
laminin, alpha 2
chr4_-_82505749 3.956 ENSMUST00000107245.2
ENSMUST00000107246.1
Nfib

nuclear factor I/B

chr6_-_136171722 3.047 ENSMUST00000053880.6
Grin2b
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr16_-_52452465 2.656 ENSMUST00000170035.1
ENSMUST00000164728.1
Alcam

activated leukocyte cell adhesion molecule

chr2_-_5063996 2.644 ENSMUST00000114996.1
Optn
optineurin
chr7_+_27653906 2.488 ENSMUST00000008088.7
Ttc9b
tetratricopeptide repeat domain 9B
chr14_+_80000292 2.451 ENSMUST00000088735.3
Olfm4
olfactomedin 4
chr11_+_78188737 2.439 ENSMUST00000108322.2
Rab34
RAB34, member of RAS oncogene family
chr18_+_37496997 2.425 ENSMUST00000059571.5
Pcdhb19
protocadherin beta 19
chr16_+_38089001 2.397 ENSMUST00000023507.6
Gsk3b
glycogen synthase kinase 3 beta
chr7_+_99535439 2.390 ENSMUST00000098266.2
ENSMUST00000179755.1
Arrb1

arrestin, beta 1

chr7_+_99535652 2.262 ENSMUST00000032995.8
ENSMUST00000162404.1
Arrb1

arrestin, beta 1

chr2_-_113758638 2.231 ENSMUST00000099575.3
Grem1
gremlin 1
chr2_-_5063932 2.229 ENSMUST00000027986.4
Optn
optineurin
chr2_-_104257400 2.222 ENSMUST00000141159.1
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr7_-_4546567 2.146 ENSMUST00000065957.5
Syt5
synaptotagmin V
chr2_-_45113255 2.002 ENSMUST00000068415.4
ENSMUST00000127520.1
Zeb2

zinc finger E-box binding homeobox 2


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 11.1 GO:0021766 hippocampus development(GO:0021766)
0.8 10.0 GO:0048484 enteric nervous system development(GO:0048484)
1.2 4.9 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.7 4.7 GO:0034393 positive regulation of smooth muscle cell apoptotic process(GO:0034393) follicle-stimulating hormone signaling pathway(GO:0042699)
0.8 4.2 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
1.0 4.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.4 3.7 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.5 3.2 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.2 3.0 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.2 3.0 GO:0050966 detection of mechanical stimulus involved in sensory perception of pain(GO:0050966)
0.1 2.7 GO:0008045 motor neuron axon guidance(GO:0008045)
0.1 2.5 GO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling(GO:0043124)
1.2 2.4 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.7 2.2 GO:1901228 regulation of osteoclast proliferation(GO:0090289) negative regulation of bone mineralization involved in bone maturation(GO:1900158) positive regulation of transcription from RNA polymerase II promoter involved in heart development(GO:1901228)
0.0 2.2 GO:0098792 xenophagy(GO:0098792)
0.1 2.1 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 2.1 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.3 2.0 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.5 1.8 GO:0009597 detection of virus(GO:0009597)
0.1 1.6 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 11.3 GO:0031225 anchored component of membrane(GO:0031225)
1.2 10.0 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.3 4.7 GO:0031143 pseudopodium(GO:0031143)
0.2 4.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 3.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.1 3.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 3.2 GO:0005802 trans-Golgi network(GO:0005802)
0.3 3.0 GO:0043083 synaptic cleft(GO:0043083)
0.2 2.5 GO:0042581 specific granule(GO:0042581)
0.2 2.4 GO:1990909 Wnt signalosome(GO:1990909)
0.1 2.4 GO:0030667 secretory granule membrane(GO:0030667)
0.1 2.0 GO:0031045 dense core granule(GO:0031045)
0.6 1.9 GO:0071953 elastic fiber(GO:0071953)
0.0 1.8 GO:0005923 bicellular tight junction(GO:0005923)
0.1 1.6 GO:0005605 basal lamina(GO:0005605)
0.0 1.6 GO:0060170 ciliary membrane(GO:0060170)
0.5 1.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.2 1.4 GO:0033010 paranodal junction(GO:0033010)
0.2 1.4 GO:0042382 paraspeckles(GO:0042382)
0.4 1.3 GO:0000802 transverse filament(GO:0000802)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 11.1 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 10.8 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.6 4.9 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
1.6 4.7 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 4.0 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.1 3.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.3 3.0 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.1 2.9 GO:0070412 R-SMAD binding(GO:0070412)
0.1 2.5 GO:0045296 cadherin binding(GO:0045296)
0.1 2.4 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.2 2.2 GO:0043184 vascular endothelial growth factor receptor 2 binding(GO:0043184)
0.1 2.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.1 1.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 1.8 GO:0003725 double-stranded RNA binding(GO:0003725)
0.4 1.4 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.1 1.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.4 GO:0005125 cytokine activity(GO:0005125)
0.1 1.3 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.1 1.3 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.1 1.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)