Motif ID: Hmbox1

Z-value: 1.058


Transcription factors associated with Hmbox1:

Gene SymbolEntrez IDGene Name
Hmbox1 ENSMUSG00000021972.8 Hmbox1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmbox1mm10_v2_chr14_-_64949632_649496740.162.3e-01Click!


Activity profile for motif Hmbox1.

activity profile for motif Hmbox1


Sorted Z-values histogram for motif Hmbox1

Sorted Z-values for motif Hmbox1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmbox1

PNG image of the network

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Top targets:


Showing 1 to 20 of 138 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_+_5390387 22.390 ENSMUST00000183358.1
 Asb4
ankyrin repeat and SOCS box-containing 4
chr6_-_23248264 21.560 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chrX_+_100625737 7.163 ENSMUST00000048962.3
 Kif4
kinesin family member 4
chr13_-_3893556 6.684 ENSMUST00000099946.4
 Net1
neuroepithelial cell transforming gene 1
chr3_-_100969644 6.042 ENSMUST00000076941.5
 Ttf2
transcription termination factor, RNA polymerase II
chrX_+_159303266 5.146 ENSMUST00000112491.1
 Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr10_+_22158566 4.890 ENSMUST00000181645.1
ENSMUST00000105522.2
 Raet1e
H60b
retinoic acid early transcript 1E
histocompatibility 60b
chr10_+_39133981 4.540 ENSMUST00000019991.7
 Tube1
epsilon-tubulin 1
chr7_-_25788635 4.331 ENSMUST00000002677.4
ENSMUST00000085948.4
 Axl

AXL receptor tyrosine kinase

chr1_-_163289214 4.276 ENSMUST00000183691.1
 Prrx1
paired related homeobox 1
chr2_-_172043466 4.276 ENSMUST00000087950.3
 Cbln4
cerebellin 4 precursor protein
chr15_+_25773985 4.054 ENSMUST00000125667.1
 Myo10
myosin X
chrX_+_169685191 4.005 ENSMUST00000112104.1
ENSMUST00000112107.1
 Mid1

midline 1

chr11_-_94507337 3.623 ENSMUST00000040692.8
 Mycbpap
MYCBP associated protein
chr13_-_74807913 3.530 ENSMUST00000065629.4
 Cast
calpastatin
chr4_+_128993224 3.218 ENSMUST00000030583.6
ENSMUST00000102604.4
 Ak2

adenylate kinase 2

chr3_-_95217690 2.954 ENSMUST00000107209.1
 Gabpb2
GA repeat binding protein, beta 2
chrX_-_23266751 2.947 ENSMUST00000115316.2
 Klhl13
kelch-like 13
chr10_+_11609256 2.874 ENSMUST00000052902.7
 Gm9797
predicted pseudogene 9797
chr1_-_75278345 2.859 ENSMUST00000039534.4
 Resp18
regulated endocrine-specific protein 18

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.2 22.4 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
3.6 21.6 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.0 7.2 GO:0000022 mitotic spindle elongation(GO:0000022) mitotic spindle midzone assembly(GO:0051256)
0.4 6.7 GO:0051451 myoblast migration(GO:0051451)
0.2 6.4 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.3 6.0 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.4 5.0 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.2 4.9 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 4.6 GO:0006821 chloride transport(GO:0006821)
1.1 4.3 GO:2000668 dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668)
0.4 4.3 GO:0048664 neuron fate determination(GO:0048664)
0.1 4.2 GO:0002224 toll-like receptor signaling pathway(GO:0002224)
0.0 4.1 GO:0022409 positive regulation of cell-cell adhesion(GO:0022409)
0.1 3.6 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.5 3.5 GO:0007343 egg activation(GO:0007343)
0.5 3.2 GO:0006172 ADP biosynthetic process(GO:0006172)
0.3 3.0 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.2 3.0 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 2.8 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 2.6 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
5.6 22.4 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 9.2 GO:0005730 nucleolus(GO:0005730)
0.1 7.4 GO:0005874 microtubule(GO:0005874)
0.1 6.5 GO:0005871 kinesin complex(GO:0005871)
0.0 6.0 GO:0005681 spliceosomal complex(GO:0005681)
0.0 5.5 GO:0030496 midbody(GO:0030496)
1.6 4.9 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.1 4.6 GO:0034707 chloride channel complex(GO:0034707)
0.2 4.3 GO:0043657 host(GO:0018995) host cell part(GO:0033643) host cell(GO:0043657)
0.1 3.3 GO:0016459 myosin complex(GO:0016459)
0.6 3.2 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.6 2.9 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 2.4 GO:0031519 PcG protein complex(GO:0031519)
0.2 2.3 GO:0042788 polysomal ribosome(GO:0042788)
0.1 2.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 2.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.2 2.1 GO:0045298 tubulin complex(GO:0045298)
0.3 1.9 GO:0070187 telosome(GO:0070187)
0.0 1.9 GO:0000775 chromosome, centromeric region(GO:0000775)
0.1 1.7 GO:0030134 ER to Golgi transport vesicle(GO:0030134)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 20.9 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.1 19.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.2 8.7 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 8.3 GO:0044212 transcription regulatory region DNA binding(GO:0044212)
0.3 6.7 GO:0017049 GTP-Rho binding(GO:0017049)
0.4 6.5 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 6.4 GO:0043774 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity(GO:0008766) ribosomal S6-glutamic acid ligase activity(GO:0018169) coenzyme F420-0 gamma-glutamyl ligase activity(GO:0043773) coenzyme F420-2 alpha-glutamyl ligase activity(GO:0043774) protein-glycine ligase activity(GO:0070735) protein-glycine ligase activity, initiating(GO:0070736) protein-glycine ligase activity, elongating(GO:0070737) tubulin-glycine ligase activity(GO:0070738)
0.6 4.9 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.1 4.9 GO:0005254 chloride channel activity(GO:0005254)
0.0 4.6 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.4 4.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 4.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 4.2 GO:0000287 magnesium ion binding(GO:0000287)
0.1 4.1 GO:0030507 spectrin binding(GO:0030507)
0.3 3.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.5 3.0 GO:0000213 tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 3.0 GO:0001671 ATPase activator activity(GO:0001671)
0.5 2.8 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 2.8 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 2.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)