Motif ID: Hmga2
Z-value: 1.199
Transcription factors associated with Hmga2:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hmga2 | ENSMUSG00000056758.8 | Hmga2 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Hmga2 | mm10_v2_chr10_-_120476469_120476527 | -0.10 | 4.4e-01 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.0 | 3.1 | GO:0090526 | regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526) |
0.9 | 5.5 | GO:0016080 | synaptic vesicle targeting(GO:0016080) |
0.7 | 2.7 | GO:2000427 | positive regulation of apoptotic cell clearance(GO:2000427) |
0.6 | 1.7 | GO:0042320 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) positive regulation of cortisol secretion(GO:0051464) |
0.5 | 1.5 | GO:0070269 | pyroptosis(GO:0070269) |
0.5 | 2.5 | GO:0006369 | termination of RNA polymerase II transcription(GO:0006369) |
0.5 | 1.4 | GO:0010636 | positive regulation of mitochondrial fusion(GO:0010636) |
0.4 | 2.7 | GO:0017121 | phospholipid scrambling(GO:0017121) |
0.4 | 2.3 | GO:0032929 | negative regulation of macrophage derived foam cell differentiation(GO:0010745) negative regulation of superoxide anion generation(GO:0032929) |
0.3 | 3.2 | GO:0010650 | positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827) |
0.3 | 3.3 | GO:0010807 | regulation of synaptic vesicle priming(GO:0010807) |
0.3 | 1.3 | GO:0021631 | optic nerve morphogenesis(GO:0021631) |
0.2 | 1.9 | GO:0016338 | calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338) |
0.2 | 0.7 | GO:0070543 | response to linoleic acid(GO:0070543) |
0.2 | 1.7 | GO:0006561 | proline biosynthetic process(GO:0006561) |
0.2 | 0.8 | GO:0010519 | negative regulation of phospholipase activity(GO:0010519) |
0.2 | 1.4 | GO:0090315 | negative regulation of protein targeting to membrane(GO:0090315) |
0.1 | 2.2 | GO:0006120 | mitochondrial electron transport, NADH to ubiquinone(GO:0006120) |
0.1 | 1.7 | GO:1900383 | regulation of synaptic plasticity by receptor localization to synapse(GO:1900383) |
0.1 | 0.6 | GO:0070535 | histone H2A K63-linked ubiquitination(GO:0070535) |
0.1 | 1.5 | GO:0031937 | positive regulation of chromatin silencing(GO:0031937) |
0.1 | 1.7 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
0.1 | 0.3 | GO:0048388 | endosomal lumen acidification(GO:0048388) |
0.1 | 1.0 | GO:0000712 | resolution of meiotic recombination intermediates(GO:0000712) |
0.1 | 2.0 | GO:0019835 | cytolysis(GO:0019835) |
0.1 | 0.7 | GO:2000598 | regulation of cyclin catabolic process(GO:2000598) negative regulation of cyclin catabolic process(GO:2000599) |
0.1 | 1.2 | GO:0070932 | histone H3 deacetylation(GO:0070932) |
0.1 | 0.6 | GO:0043983 | histone H4-K12 acetylation(GO:0043983) |
0.1 | 0.3 | GO:0035521 | monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522) histone H2A K63-linked deubiquitination(GO:0070537) |
0.1 | 0.9 | GO:0007168 | receptor guanylyl cyclase signaling pathway(GO:0007168) |
0.1 | 0.3 | GO:0010890 | positive regulation of sequestering of triglyceride(GO:0010890) |
0.1 | 6.4 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.1 | 1.3 | GO:0034390 | smooth muscle cell apoptotic process(GO:0034390) regulation of smooth muscle cell apoptotic process(GO:0034391) cGMP catabolic process(GO:0046069) |
0.1 | 2.0 | GO:0018345 | protein palmitoylation(GO:0018345) |
0.1 | 0.3 | GO:0046294 | formaldehyde catabolic process(GO:0046294) |
0.1 | 0.6 | GO:0061088 | sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088) |
0.1 | 1.2 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
0.1 | 0.2 | GO:0035609 | C-terminal protein deglutamylation(GO:0035609) |
0.1 | 0.9 | GO:1900454 | positive regulation of long term synaptic depression(GO:1900454) |
0.1 | 0.4 | GO:0034551 | respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033) |
0.0 | 1.1 | GO:0042773 | ATP synthesis coupled electron transport(GO:0042773) |
0.0 | 0.4 | GO:0010606 | positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606) |
0.0 | 0.4 | GO:0001672 | regulation of chromatin assembly or disassembly(GO:0001672) |
0.0 | 0.6 | GO:0031100 | organ regeneration(GO:0031100) |
0.0 | 0.0 | GO:0006404 | RNA import into nucleus(GO:0006404) |
0.0 | 8.4 | GO:0000398 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
0.0 | 0.7 | GO:0071425 | hematopoietic stem cell proliferation(GO:0071425) |
0.0 | 0.1 | GO:0090071 | negative regulation of ribosome biogenesis(GO:0090071) |
0.0 | 0.7 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
0.0 | 1.7 | GO:0035904 | aorta development(GO:0035904) |
0.0 | 0.1 | GO:0033540 | fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540) |
0.0 | 1.1 | GO:0045214 | sarcomere organization(GO:0045214) |
0.0 | 0.6 | GO:0006862 | nucleotide transport(GO:0006862) |
0.0 | 0.9 | GO:0034605 | cellular response to heat(GO:0034605) |
0.0 | 0.2 | GO:0035970 | peptidyl-threonine dephosphorylation(GO:0035970) |
0.0 | 1.3 | GO:0007156 | homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156) |
0.0 | 0.1 | GO:0070914 | UV-damage excision repair(GO:0070914) |
0.0 | 0.3 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
1.1 | 5.5 | GO:0044316 | cone cell pedicle(GO:0044316) |
1.1 | 8.6 | GO:0089701 | U2AF(GO:0089701) |
0.9 | 2.7 | GO:0044299 | C-fiber(GO:0044299) |
0.7 | 3.3 | GO:0070044 | synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044) |
0.4 | 2.1 | GO:0048237 | rough endoplasmic reticulum lumen(GO:0048237) |
0.4 | 1.2 | GO:1990415 | Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429) |
0.4 | 1.5 | GO:0061702 | inflammasome complex(GO:0061702) |
0.3 | 3.1 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.2 | 1.4 | GO:0031314 | extrinsic component of mitochondrial inner membrane(GO:0031314) |
0.2 | 1.9 | GO:0070688 | MLL5-L complex(GO:0070688) |
0.2 | 0.6 | GO:0036156 | inner dynein arm(GO:0036156) |
0.2 | 0.5 | GO:0005940 | septin ring(GO:0005940) |
0.2 | 3.2 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
0.1 | 3.2 | GO:0030131 | clathrin adaptor complex(GO:0030131) |
0.1 | 0.4 | GO:0044530 | supraspliceosomal complex(GO:0044530) |
0.0 | 1.1 | GO:0005865 | striated muscle thin filament(GO:0005865) |
0.0 | 1.9 | GO:0016328 | lateral plasma membrane(GO:0016328) |
0.0 | 2.4 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 0.1 | GO:0031465 | Cul4B-RING E3 ubiquitin ligase complex(GO:0031465) |
0.0 | 0.4 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.0 | 0.6 | GO:0035861 | site of double-strand break(GO:0035861) |
0.0 | 0.9 | GO:0005834 | heterotrimeric G-protein complex(GO:0005834) |
0.0 | 0.6 | GO:0035145 | exon-exon junction complex(GO:0035145) |
0.0 | 0.8 | GO:0005801 | cis-Golgi network(GO:0005801) |
0.0 | 2.5 | GO:0000781 | chromosome, telomeric region(GO:0000781) |
0.0 | 0.8 | GO:0009898 | cytoplasmic side of plasma membrane(GO:0009898) |
0.0 | 1.1 | GO:0005643 | nuclear pore(GO:0005643) |
0.0 | 1.4 | GO:0030496 | midbody(GO:0030496) |
0.0 | 0.5 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
0.0 | 2.5 | GO:0019898 | extrinsic component of membrane(GO:0019898) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.8 | 2.5 | GO:0001160 | transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) |
0.8 | 3.3 | GO:0005483 | soluble NSF attachment protein activity(GO:0005483) |
0.7 | 2.7 | GO:0031727 | CCR2 chemokine receptor binding(GO:0031727) |
0.6 | 1.9 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
0.5 | 2.3 | GO:0001849 | complement component C1q binding(GO:0001849) |
0.4 | 5.5 | GO:0005522 | profilin binding(GO:0005522) |
0.4 | 1.7 | GO:0004735 | pyrroline-5-carboxylate reductase activity(GO:0004735) |
0.4 | 3.1 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.4 | 1.4 | GO:0005093 | Rab GDP-dissociation inhibitor activity(GO:0005093) |
0.2 | 0.7 | GO:0070892 | lipoteichoic acid receptor activity(GO:0070892) |
0.2 | 1.3 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
0.2 | 1.7 | GO:0008499 | UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499) |
0.2 | 1.3 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
0.2 | 2.7 | GO:0017128 | phospholipid scramblase activity(GO:0017128) |
0.1 | 1.7 | GO:0030296 | protein tyrosine kinase activator activity(GO:0030296) |
0.1 | 3.2 | GO:0008093 | cytoskeletal adaptor activity(GO:0008093) |
0.1 | 3.3 | GO:0050136 | NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136) |
0.1 | 0.3 | GO:0018738 | S-formylglutathione hydrolase activity(GO:0018738) |
0.1 | 2.0 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
0.0 | 2.9 | GO:0030276 | clathrin binding(GO:0030276) |
0.0 | 1.1 | GO:0019789 | SUMO transferase activity(GO:0019789) |
0.0 | 0.3 | GO:0015250 | water channel activity(GO:0015250) |
0.0 | 1.7 | GO:0046875 | ephrin receptor binding(GO:0046875) |
0.0 | 0.6 | GO:0015215 | nucleotide transmembrane transporter activity(GO:0015215) |
0.0 | 1.5 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
0.0 | 0.9 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
0.0 | 0.6 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
0.0 | 0.7 | GO:0031490 | chromatin DNA binding(GO:0031490) |
0.0 | 0.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
0.0 | 0.4 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
0.0 | 0.8 | GO:0001965 | G-protein alpha-subunit binding(GO:0001965) |
0.0 | 0.1 | GO:0003997 | acyl-CoA oxidase activity(GO:0003997) |
0.0 | 0.6 | GO:0042162 | telomeric DNA binding(GO:0042162) |
0.0 | 3.3 | GO:0008017 | microtubule binding(GO:0008017) |
0.0 | 0.2 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
0.0 | 0.5 | GO:0031369 | translation initiation factor binding(GO:0031369) |
0.0 | 0.7 | GO:0019003 | GDP binding(GO:0019003) |