Motif ID: Hmga2

Z-value: 1.199


Transcription factors associated with Hmga2:

Gene SymbolEntrez IDGene Name
Hmga2 ENSMUSG00000056758.8 Hmga2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmga2mm10_v2_chr10_-_120476469_120476527-0.104.4e-01Click!


Activity profile for motif Hmga2.

activity profile for motif Hmga2


Sorted Z-values histogram for motif Hmga2

Sorted Z-values for motif Hmga2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmga2

PNG image of the network

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Top targets:


Showing 1 to 20 of 136 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_3013140 17.852 ENSMUST00000143083.2
Gm10721
predicted gene 10721
chr14_-_19418930 17.752 ENSMUST00000177817.1
Gm21738
predicted gene, 21738
chr2_-_98667264 17.576 ENSMUST00000099683.1
Gm10800
predicted gene 10800
chr9_+_3004457 14.841 ENSMUST00000178348.1
Gm11168
predicted gene 11168
chr9_+_3025417 12.019 ENSMUST00000075573.6
Gm10717
predicted gene 10717
chr9_+_3023547 11.755 ENSMUST00000099046.3
Gm10718
predicted gene 10718
chr9_+_3018753 11.008 ENSMUST00000179272.1
Gm10719
predicted gene 10719
chr9_+_3017408 9.718 ENSMUST00000099049.3
Gm10719
predicted gene 10719
chr11_+_22971991 8.637 ENSMUST00000049506.5
Zrsr1
zinc finger (CCCH type), RNA binding motif and serine/arginine rich 1
chr5_+_14514918 5.523 ENSMUST00000030691.10
ENSMUST00000182407.1
Pclo

piccolo (presynaptic cytomatrix protein)

chr7_-_5413145 4.214 ENSMUST00000108569.2
Vmn1r58
vomeronasal 1 receptor 58
chr3_+_53845086 3.624 ENSMUST00000108014.1
Gm10985
predicted gene 10985
chr9_-_123260776 3.571 ENSMUST00000068140.4
Tmem158
transmembrane protein 158
chr2_-_148732457 3.302 ENSMUST00000028926.6
Napb
N-ethylmaleimide sensitive fusion protein attachment protein beta
chr10_+_69787431 3.170 ENSMUST00000183240.1
Ank3
ankyrin 3, epithelial
chr1_+_66386968 3.149 ENSMUST00000145419.1
Map2
microtubule-associated protein 2
chr12_-_23780265 3.089 ENSMUST00000072014.4
Gm10330
predicted gene 10330
chr10_+_123264076 2.874 ENSMUST00000050756.7
Fam19a2
family with sequence similarity 19, member A2
chr9_+_92309362 2.746 ENSMUST00000098477.1
ENSMUST00000150594.1
1700057G04Rik

RIKEN cDNA 1700057G04 gene

chr11_+_82035569 2.652 ENSMUST00000000193.5
Ccl2
chemokine (C-C motif) ligand 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 8.4 GO:0000398 RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 6.4 GO:0001578 microtubule bundle formation(GO:0001578)
0.9 5.5 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.3 3.3 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.3 3.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
1.0 3.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.7 2.7 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.4 2.7 GO:0017121 phospholipid scrambling(GO:0017121)
0.5 2.5 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.4 2.3 GO:0032929 negative regulation of macrophage derived foam cell differentiation(GO:0010745) negative regulation of superoxide anion generation(GO:0032929)
0.1 2.2 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 2.0 GO:0019835 cytolysis(GO:0019835)
0.1 2.0 GO:0018345 protein palmitoylation(GO:0018345)
0.2 1.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.6 1.7 GO:0042320 regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) positive regulation of cortisol secretion(GO:0051464)
0.2 1.7 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 1.7 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1 1.7 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 1.7 GO:0035904 aorta development(GO:0035904)
0.5 1.5 GO:0070269 pyroptosis(GO:0070269)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.1 8.6 GO:0089701 U2AF(GO:0089701)
1.1 5.5 GO:0044316 cone cell pedicle(GO:0044316)
0.7 3.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.2 3.2 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 3.2 GO:0030131 clathrin adaptor complex(GO:0030131)
0.3 3.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.9 2.7 GO:0044299 C-fiber(GO:0044299)
0.0 2.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.0 2.5 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 2.4 GO:0070469 respiratory chain(GO:0070469)
0.4 2.1 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.2 1.9 GO:0070688 MLL5-L complex(GO:0070688)
0.0 1.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.4 1.5 GO:0061702 inflammasome complex(GO:0061702)
0.2 1.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 1.4 GO:0030496 midbody(GO:0030496)
0.4 1.2 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 1.1 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 1.1 GO:0005643 nuclear pore(GO:0005643)
0.0 0.9 GO:0005834 heterotrimeric G-protein complex(GO:0005834)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.5 GO:0005522 profilin binding(GO:0005522)
0.8 3.3 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 3.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 3.3 GO:0008017 microtubule binding(GO:0008017)
0.1 3.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.4 3.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 2.9 GO:0030276 clathrin binding(GO:0030276)
0.7 2.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.2 2.7 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.8 2.5 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.5 2.3 GO:0001849 complement component C1q binding(GO:0001849)
0.1 2.0 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.6 1.9 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.4 1.7 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.2 1.7 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.1 1.7 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 1.7 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.5 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.4 1.4 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.2 1.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)