Motif ID: Hmx3

Z-value: 0.303


Transcription factors associated with Hmx3:

Gene SymbolEntrez IDGene Name
Hmx3 ENSMUSG00000040148.5 Hmx3

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hmx3mm10_v2_chr7_+_131542867_1315428670.162.2e-01Click!


Activity profile for motif Hmx3.

activity profile for motif Hmx3


Sorted Z-values histogram for motif Hmx3

Sorted Z-values for motif Hmx3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hmx3

PNG image of the network

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Top targets:


Showing 1 to 20 of 59 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_-_86548268 1.178 ENSMUST00000077524.3
 Mab21l2
mab-21-like 2 (C. elegans)
chr1_-_78968079 0.934 ENSMUST00000049117.5
 Gm5830
predicted pseudogene 5830
chr1_-_175979114 0.885 ENSMUST00000104983.1
 B020018G12Rik
RIKEN cDNA B020018G12 gene
chr3_-_154328634 0.867 ENSMUST00000167744.1
 Lhx8
LIM homeobox protein 8
chr4_-_45532470 0.858 ENSMUST00000147448.1
 Shb
src homology 2 domain-containing transforming protein B
chr2_+_3114220 0.785 ENSMUST00000072955.5
 Fam171a1
family with sequence similarity 171, member A1
chr5_+_15516489 0.771 ENSMUST00000178227.1
 Gm21847
predicted gene, 21847
chr13_+_118714678 0.721 ENSMUST00000022246.8
 Fgf10
fibroblast growth factor 10
chr4_-_129261394 0.689 ENSMUST00000145261.1
 C77080
expressed sequence C77080
chr5_-_53707532 0.674 ENSMUST00000031093.3
 Cckar
cholecystokinin A receptor
chr10_+_99263224 0.672 ENSMUST00000020118.4
 Dusp6
dual specificity phosphatase 6
chr18_+_61639542 0.576 ENSMUST00000183083.1
ENSMUST00000183087.1
 Gm20748

predicted gene, 20748

chr7_-_30559828 0.541 ENSMUST00000108164.1
 Lin37
lin-37 homolog (C. elegans)
chr7_+_3645267 0.517 ENSMUST00000038913.9
 Cnot3
CCR4-NOT transcription complex, subunit 3
chr7_-_30559600 0.483 ENSMUST00000043975.4
ENSMUST00000156241.1
 Lin37

lin-37 homolog (C. elegans)

chr11_+_103133303 0.475 ENSMUST00000107037.1
 Hexim2
hexamethylene bis-acetamide inducible 2
chr3_+_96629919 0.459 ENSMUST00000048915.6
 Rbm8a
RNA binding motif protein 8a
chr5_-_87482258 0.441 ENSMUST00000079811.6
ENSMUST00000144144.1
 Ugt2a1

UDP glucuronosyltransferase 2 family, polypeptide A1

chr3_-_49757257 0.436 ENSMUST00000035931.7
 Pcdh18
protocadherin 18
chrM_+_9452 0.434 ENSMUST00000082411.1
 mt-Nd3
mitochondrially encoded NADH dehydrogenase 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 25 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.2 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 0.9 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.0 0.9 GO:0021884 forebrain neuron development(GO:0021884)
0.0 0.8 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.2 0.7 GO:0071336 lung growth(GO:0060437) positive regulation of fat cell proliferation(GO:0070346) regulation of hair follicle cell proliferation(GO:0071336) positive regulation of hair follicle cell proliferation(GO:0071338)
0.2 0.7 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.2 0.7 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.6 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.5 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.5 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.1 0.4 GO:1903265 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172) positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 0.4 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.4 GO:0048318 axial mesoderm development(GO:0048318)
0.1 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.4 GO:0071385 cellular response to glucocorticoid stimulus(GO:0071385)
0.1 0.3 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.3 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.3 GO:0036233 glycine import(GO:0036233)
0.0 0.3 GO:0007320 insemination(GO:0007320)

Gene overrepresentation in cellular_component category:

Showing 1 to 13 of 13 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 0.9 GO:0001674 female germ cell nucleus(GO:0001674)
0.1 0.5 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.5 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 0.4 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.4 GO:0032982 myosin filament(GO:0032982)
0.0 0.4 GO:0071565 nBAF complex(GO:0071565)
0.0 0.4 GO:0000788 nuclear nucleosome(GO:0000788)
0.1 0.3 GO:0000811 GINS complex(GO:0000811)
0.0 0.3 GO:0060293 P granule(GO:0043186) pole plasm(GO:0045495) germ plasm(GO:0060293)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.1 GO:0002944 cyclin K-CDK12 complex(GO:0002944)
0.0 0.1 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)

Gene overrepresentation in molecular_function category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 0.9 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.1 0.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 0.7 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.7 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.6 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706)
0.1 0.4 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.1 0.3 GO:0070644 vitamin D response element binding(GO:0070644)
0.1 0.3 GO:0015375 glycine:sodium symporter activity(GO:0015375)
0.0 0.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.3 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.3 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)