Motif ID: Hnf1b

Z-value: 1.011


Transcription factors associated with Hnf1b:

Gene SymbolEntrez IDGene Name
Hnf1b ENSMUSG00000020679.5 Hnf1b



Activity profile for motif Hnf1b.

activity profile for motif Hnf1b


Sorted Z-values histogram for motif Hnf1b

Sorted Z-values for motif Hnf1b



Network of associatons between targets according to the STRING database.



First level regulatory network of Hnf1b

PNG image of the network

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Top targets:


Showing 1 to 20 of 129 entries
PromoterScoreRefseqGene SymbolGene Name
chr4_-_106464167 9.494 ENSMUST00000049507.5
 Pcsk9
proprotein convertase subtilisin/kexin type 9
chr13_-_53286052 8.894 ENSMUST00000021918.8
 Ror2
receptor tyrosine kinase-like orphan receptor 2
chr7_-_144751968 8.449 ENSMUST00000155175.1
 Ano1
anoctamin 1, calcium activated chloride channel
chrX_+_52791179 8.277 ENSMUST00000101588.1
 Ccdc160
coiled-coil domain containing 160
chr9_-_106158109 8.238 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
 Glyctk



glycerate kinase



chr11_-_76027726 7.982 ENSMUST00000021207.6
 Fam101b
family with sequence similarity 101, member B
chr10_-_7212222 7.800 ENSMUST00000015346.5
 Cnksr3
Cnksr family member 3
chr4_-_134767940 6.931 ENSMUST00000037828.6
 Ldlrap1
low density lipoprotein receptor adaptor protein 1
chr3_+_154597352 5.855 ENSMUST00000140644.1
ENSMUST00000144764.1
ENSMUST00000155232.1
 Cryz


crystallin, zeta


chr2_+_167777467 5.415 ENSMUST00000139927.1
ENSMUST00000127441.1
 Gm14321

predicted gene 14321

chr19_+_23723279 5.382 ENSMUST00000067077.1
 Gm9938
predicted gene 9938
chr9_+_99629496 5.129 ENSMUST00000131095.1
ENSMUST00000078367.5
ENSMUST00000112885.2
 Dzip1l


DAZ interacting protein 1-like


chr1_-_4880669 4.996 ENSMUST00000078030.3
 Gm6104
predicted gene 6104
chr13_+_89540636 4.907 ENSMUST00000022108.7
 Hapln1
hyaluronan and proteoglycan link protein 1
chr3_-_138131356 4.767 ENSMUST00000029805.8
 Mttp
microsomal triglyceride transfer protein
chr9_+_15520830 4.527 ENSMUST00000178999.1
 Smco4
single-pass membrane protein with coiled-coil domains 4
chr10_-_76110956 4.507 ENSMUST00000120757.1
 Slc5a4b
solute carrier family 5 (neutral amino acid transporters, system A), member 4b
chr1_+_19208914 4.413 ENSMUST00000027059.4
 Tfap2b
transcription factor AP-2 beta
chr15_-_36598019 4.359 ENSMUST00000155116.1
 Pabpc1
poly(A) binding protein, cytoplasmic 1
chr9_+_99629823 4.329 ENSMUST00000112886.2
 Dzip1l
DAZ interacting protein 1-like

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 79 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.2 9.5 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
1.8 8.9 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
1.7 8.4 GO:0015705 iodide transport(GO:0015705)
2.7 8.0 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.3 7.8 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
2.3 7.0 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.6 6.9 GO:0034383 low-density lipoprotein particle clearance(GO:0034383)
0.0 6.7 GO:0016055 Wnt signaling pathway(GO:0016055) cell-cell signaling by wnt(GO:0198738)
0.4 5.9 GO:0042178 xenobiotic catabolic process(GO:0042178)
0.9 5.3 GO:0098700 aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700)
1.0 4.8 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.8 4.5 GO:0035428 hexose transmembrane transport(GO:0035428)
1.5 4.4 GO:0097274 urea homeostasis(GO:0097274)
0.9 4.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 3.9 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.1 3.9 GO:0080171 lysosome organization(GO:0007040) lytic vacuole organization(GO:0080171)
0.5 3.7 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146)
0.1 3.7 GO:0072698 protein localization to microtubule cytoskeleton(GO:0072698)
1.2 3.6 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.7 3.6 GO:0072757 cellular response to camptothecin(GO:0072757)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.2 9.5 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 9.5 GO:0005814 centriole(GO:0005814)
0.2 8.4 GO:0034707 chloride channel complex(GO:0034707)
0.4 7.0 GO:0031143 pseudopodium(GO:0031143)
1.7 6.9 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 6.8 GO:0005667 transcription factor complex(GO:0005667)
0.0 4.9 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.3 4.8 GO:0031528 microvillus membrane(GO:0031528)
0.2 4.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 4.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 4.0 GO:0000139 Golgi membrane(GO:0000139)
0.2 3.9 GO:0033655 host cell cytoplasm(GO:0030430) host cell cytoplasm part(GO:0033655)
0.3 3.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.2 3.7 GO:0010369 chromocenter(GO:0010369)
0.1 3.6 GO:0043034 costamere(GO:0043034)
0.1 3.5 GO:0044295 axonal growth cone(GO:0044295)
0.9 2.7 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.2 2.7 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 2.2 GO:0008021 synaptic vesicle(GO:0008021)
0.6 1.9 GO:1990730 VCP-NSFL1C complex(GO:1990730)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 11.5 GO:0070491 repressing transcription factor binding(GO:0070491)
3.2 9.5 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.3 8.9 GO:0017147 Wnt-protein binding(GO:0017147)
2.1 8.4 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.5 8.0 GO:0031005 filamin binding(GO:0031005)
0.1 7.0 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.8 6.9 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 6.5 GO:0000978 RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978)
0.3 5.9 GO:0070402 NADPH binding(GO:0070402)
1.3 5.3 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.3 5.2 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.3 4.9 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 4.8 GO:0008143 poly(A) binding(GO:0008143)
0.3 4.4 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.3 3.9 GO:0005537 mannose binding(GO:0005537)
0.5 3.7 GO:0016714 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced pteridine as one donor, and incorporation of one atom of oxygen(GO:0016714)
0.1 3.7 GO:0019894 kinesin binding(GO:0019894)
0.9 3.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.0 3.6 GO:0051015 actin filament binding(GO:0051015)
0.7 3.5 GO:0032767 copper-dependent protein binding(GO:0032767)