Motif ID: Hnf4a

Z-value: 0.642


Transcription factors associated with Hnf4a:

Gene SymbolEntrez IDGene Name
Hnf4a ENSMUSG00000017950.10 Hnf4a



Activity profile for motif Hnf4a.

activity profile for motif Hnf4a


Sorted Z-values histogram for motif Hnf4a

Sorted Z-values for motif Hnf4a



Network of associatons between targets according to the STRING database.



First level regulatory network of Hnf4a

PNG image of the network

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Top targets:


Showing 1 to 20 of 183 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_131042682 4.096 ENSMUST00000028787.5
ENSMUST00000110239.1
ENSMUST00000110234.1
Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr11_+_104282371 4.055 ENSMUST00000106988.1
ENSMUST00000106989.1
Mapt

microtubule-associated protein tau

chr2_-_131043088 3.787 ENSMUST00000110240.3
ENSMUST00000066958.4
ENSMUST00000110235.1
Gfra4


glial cell line derived neurotrophic factor family receptor alpha 4


chr14_+_101840602 3.672 ENSMUST00000159314.1
Lmo7
LIM domain only 7
chr14_+_101840501 3.280 ENSMUST00000159026.1
Lmo7
LIM domain only 7
chr9_-_77347816 2.927 ENSMUST00000184138.1
ENSMUST00000184006.1
ENSMUST00000185144.1
ENSMUST00000034910.9
Mlip



muscular LMNA-interacting protein



chr7_+_45896941 2.865 ENSMUST00000069772.7
ENSMUST00000107716.1
Tmem143

transmembrane protein 143

chr11_-_81968415 2.541 ENSMUST00000066197.6
Asic2
acid-sensing (proton-gated) ion channel 2
chr4_+_136286061 2.481 ENSMUST00000069195.4
ENSMUST00000130658.1
Zfp46

zinc finger protein 46

chr7_+_25268387 2.475 ENSMUST00000169392.1
Cic
capicua homolog (Drosophila)
chrX_-_162565514 2.368 ENSMUST00000154424.1
Reps2
RALBP1 associated Eps domain containing protein 2
chr9_-_77347787 2.211 ENSMUST00000184848.1
ENSMUST00000184415.1
Mlip

muscular LMNA-interacting protein

chr7_+_112225856 2.206 ENSMUST00000050149.5
ENSMUST00000106647.1
ENSMUST00000106648.1
Mical2


microtubule associated monooxygenase, calponin and LIM domain containing 2


chr7_+_45897429 2.174 ENSMUST00000140243.1
Tmem143
transmembrane protein 143
chr19_+_44992127 2.170 ENSMUST00000179305.1
Sema4g
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr15_+_82252397 2.027 ENSMUST00000136948.1
1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr15_-_102722120 1.998 ENSMUST00000171838.1
Calcoco1
calcium binding and coiled coil domain 1
chr7_+_67222544 1.974 ENSMUST00000058771.5
ENSMUST00000179106.1
Lysmd4

LysM, putative peptidoglycan-binding, domain containing 4

chr1_-_155417394 1.927 ENSMUST00000111775.1
ENSMUST00000111774.1
Xpr1

xenotropic and polytropic retrovirus receptor 1

chr15_-_102722150 1.876 ENSMUST00000023818.3
Calcoco1
calcium binding and coiled coil domain 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 75 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.9 GO:0030279 negative regulation of ossification(GO:0030279)
0.0 5.9 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.2 5.1 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.6 4.6 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.3 4.1 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.5 3.6 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 3.5 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
1.1 3.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.8 3.2 GO:0097393 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.5 3.2 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.8 2.5 GO:0050915 sensory perception of sour taste(GO:0050915)
0.1 2.3 GO:0033344 cholesterol efflux(GO:0033344)
0.4 2.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 2.2 GO:0050919 negative chemotaxis(GO:0050919)
0.0 1.8 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 1.8 GO:0048286 lung alveolus development(GO:0048286)
0.1 1.7 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.3 1.6 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.3 1.6 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 1.6 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.0 GO:0005913 cell-cell adherens junction(GO:0005913)
0.1 6.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 4.8 GO:0016605 PML body(GO:0016605)
0.4 4.1 GO:0045298 tubulin complex(GO:0045298)
0.0 3.4 GO:0043197 dendritic spine(GO:0043197)
0.8 3.2 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.5 3.2 GO:0097427 microtubule bundle(GO:0097427)
0.0 3.1 GO:0014069 postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.6 2.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.8 GO:0042734 presynaptic membrane(GO:0042734)
0.1 1.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.4 GO:0044295 axonal growth cone(GO:0044295)
0.0 1.2 GO:0005882 intermediate filament(GO:0005882)
0.2 1.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.9 GO:0070695 FHF complex(GO:0070695)
0.2 0.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.8 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.8 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.8 GO:0005884 actin filament(GO:0005884)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 62 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.6 7.9 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2 7.0 GO:0042805 actinin binding(GO:0042805)
0.0 5.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 3.9 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.2 3.8 GO:0034185 apolipoprotein binding(GO:0034185)
0.5 3.2 GO:0015616 DNA translocase activity(GO:0015616)
0.4 3.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 3.2 GO:0001191 transcriptional repressor activity, RNA polymerase II transcription factor binding(GO:0001191)
0.0 3.1 GO:0017022 myosin binding(GO:0017022)
0.0 3.0 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.5 2.8 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 2.5 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)
0.6 2.2 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.2 2.2 GO:0052872 3-(3-hydroxyphenyl)propionate hydroxylase activity(GO:0008688) 4-chlorobenzaldehyde oxidase activity(GO:0018471) 3,5-xylenol methylhydroxylase activity(GO:0018630) phenylacetate hydroxylase activity(GO:0018631) 4-nitrophenol 4-monooxygenase activity(GO:0018632) dimethyl sulfide monooxygenase activity(GO:0018633) alpha-pinene monooxygenase [NADH] activity(GO:0018634) phenanthrene 9,10-monooxygenase activity(GO:0018636) 1-hydroxy-2-naphthoate hydroxylase activity(GO:0018637) toluene 4-monooxygenase activity(GO:0018638) xylene monooxygenase activity(GO:0018639) dibenzothiophene monooxygenase activity(GO:0018640) 6-hydroxy-3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018641) chlorophenol 4-monooxygenase activity(GO:0018642) carbon disulfide oxygenase activity(GO:0018643) toluene 2-monooxygenase activity(GO:0018644) 1-hydroxy-2-oxolimonene 1,2-monooxygenase activity(GO:0018646) phenanthrene 1,2-monooxygenase activity(GO:0018647) tetrahydrofuran hydroxylase activity(GO:0018649) styrene monooxygenase activity(GO:0018650) toluene-4-sulfonate monooxygenase activity(GO:0018651) toluene-sulfonate methyl-monooxygenase activity(GO:0018652) 3-methyl-2-oxo-1,2-dihydroquinoline 6-monooxygenase activity(GO:0018653) 2-hydroxy-phenylacetate hydroxylase activity(GO:0018654) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA 1,2-monooxygenase activity(GO:0018655) phenanthrene 3,4-monooxygenase activity(GO:0018656) toluene 3-monooxygenase activity(GO:0018657) 4-hydroxyphenylacetate,NADH:oxygen oxidoreductase (3-hydroxylating) activity(GO:0018660) limonene monooxygenase activity(GO:0019113) 2-methylnaphthalene hydroxylase activity(GO:0034526) 1-methylnaphthalene hydroxylase activity(GO:0034534) bisphenol A hydroxylase A activity(GO:0034560) salicylate 5-hydroxylase activity(GO:0034785) isobutylamine N-hydroxylase activity(GO:0034791) branched-chain dodecylbenzene sulfonate monooxygenase activity(GO:0034802) 3-HSA hydroxylase activity(GO:0034819) 4-hydroxypyridine-3-hydroxylase activity(GO:0034894) 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase activity(GO:0043719) 6-hydroxynicotinate 3-monooxygenase activity(GO:0043731) tocotrienol omega-hydroxylase activity(GO:0052872) thalianol hydroxylase activity(GO:0080014)
0.4 1.8 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.1 1.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 1.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 1.8 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.0 1.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.6 GO:0005154 epidermal growth factor receptor binding(GO:0005154)