Motif ID: Hoxa1

Z-value: 0.875


Transcription factors associated with Hoxa1:

Gene SymbolEntrez IDGene Name
Hoxa1 ENSMUSG00000029844.9 Hoxa1



Activity profile for motif Hoxa1.

activity profile for motif Hoxa1


Sorted Z-values histogram for motif Hoxa1

Sorted Z-values for motif Hoxa1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa1

PNG image of the network

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Top targets:


Showing 1 to 20 of 97 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_+_15239045 8.557 ENSMUST00000034413.6
 Vstm5
V-set and transmembrane domain containing 5
chr14_+_70077375 4.849 ENSMUST00000035908.1
 Egr3
early growth response 3
chr2_+_163225363 4.116 ENSMUST00000099110.3
ENSMUST00000165937.1
 Tox2

TOX high mobility group box family member 2

chr2_+_158375638 3.614 ENSMUST00000109488.1
 Snhg11
small nucleolar RNA host gene 11
chr10_+_79988584 3.494 ENSMUST00000004784.4
ENSMUST00000105374.1
 Cnn2

calponin 2

chr8_-_11312731 3.383 ENSMUST00000033898.9
 Col4a1
collagen, type IV, alpha 1
chr13_+_72628802 3.341 ENSMUST00000074372.4
 Irx2
Iroquois related homeobox 2 (Drosophila)
chr4_-_143299498 2.941 ENSMUST00000030317.7
 Pdpn
podoplanin
chr14_-_103844173 2.780 ENSMUST00000022718.3
 Ednrb
endothelin receptor type B
chr10_+_81628702 2.623 ENSMUST00000129622.1
 Ankrd24
ankyrin repeat domain 24
chr8_-_117673682 2.499 ENSMUST00000173522.1
ENSMUST00000174450.1
 Sdr42e1

short chain dehydrogenase/reductase family 42E, member 1

chr4_-_106799779 2.375 ENSMUST00000145061.1
ENSMUST00000102762.3
 Acot11

acyl-CoA thioesterase 11

chr2_+_152962485 2.323 ENSMUST00000099197.2
ENSMUST00000103155.3
 Ttll9

tubulin tyrosine ligase-like family, member 9

chrX_+_110814390 2.186 ENSMUST00000078229.3
 Pou3f4
POU domain, class 3, transcription factor 4
chr17_+_70522083 2.110 ENSMUST00000148486.1
ENSMUST00000133717.1
 Dlgap1

discs, large (Drosophila) homolog-associated protein 1

chr5_+_27261916 2.071 ENSMUST00000101471.3
 Dpp6
dipeptidylpeptidase 6
chr6_-_52012476 2.025 ENSMUST00000078214.5
 Skap2
src family associated phosphoprotein 2
chr11_+_103774150 2.020 ENSMUST00000000127.5
 Wnt3
wingless-related MMTV integration site 3
chr13_+_72628831 1.968 ENSMUST00000169028.1
 Irx2
Iroquois related homeobox 2 (Drosophila)
chr13_+_31806627 1.958 ENSMUST00000062292.2
 Foxc1
forkhead box C1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 39 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.8 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.4 4.8 GO:0061032 visceral serous pericardium development(GO:0061032)
0.3 3.9 GO:0070842 aggresome assembly(GO:0070842)
0.2 3.9 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.5 3.4 GO:0061304 retinal blood vessel morphogenesis(GO:0061304)
0.9 2.8 GO:0014826 vein smooth muscle contraction(GO:0014826)
0.0 2.7 GO:0006694 steroid biosynthetic process(GO:0006694)
0.2 2.2 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 2.1 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
0.0 2.1 GO:0007019 microtubule depolymerization(GO:0007019)
0.7 2.0 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.7 2.0 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.0 2.0 GO:0002757 immune response-activating signal transduction(GO:0002757)
0.6 1.9 GO:0051695 actin filament uncapping(GO:0051695)
0.6 1.8 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.6 1.8 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.2 1.8 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.2 1.5 GO:0015808 L-alanine transport(GO:0015808)
0.3 1.4 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
0.1 1.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 4.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 3.7 GO:0030175 filopodium(GO:0030175)
0.7 3.4 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 2.9 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 2.8 GO:0031965 nuclear membrane(GO:0031965)
0.1 1.9 GO:0005865 striated muscle thin filament(GO:0005865)
0.6 1.8 GO:0005588 collagen type V trimer(GO:0005588)
0.0 1.8 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 1.8 GO:0043204 perikaryon(GO:0043204)
0.0 1.5 GO:0005882 intermediate filament(GO:0005882)
0.2 1.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 1.1 GO:0030667 secretory granule membrane(GO:0030667)
0.0 1.0 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.9 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 0.8 GO:0000124 SAGA complex(GO:0000124)
0.0 0.7 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.7 GO:0005876 spindle microtubule(GO:0005876)
0.2 0.6 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 4.2 GO:0008517 folic acid transporter activity(GO:0008517) water channel activity(GO:0015250)
0.0 4.1 GO:0001085 RNA polymerase II transcription factor binding(GO:0001085)
0.1 3.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 3.5 GO:0005516 calmodulin binding(GO:0005516)
0.2 3.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.9 2.8 GO:0004962 endothelin receptor activity(GO:0004962)
0.4 2.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 2.4 GO:0034946 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.2 2.2 GO:0003680 AT DNA binding(GO:0003680)
0.0 2.1 GO:0015459 potassium channel regulator activity(GO:0015459)
0.2 2.0 GO:0048018 receptor agonist activity(GO:0048018)
0.2 2.0 GO:0008301 DNA binding, bending(GO:0008301)
0.1 2.0 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.2 1.9 GO:0031432 thyroid hormone receptor coactivator activity(GO:0030375) titin binding(GO:0031432)
0.1 1.8 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 1.8 GO:0005080 protein kinase C binding(GO:0005080)
0.2 1.5 GO:0015180 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.1 1.4 GO:0051183 vitamin transporter activity(GO:0051183)
0.2 1.3 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 1.3 GO:1990459 transferrin receptor binding(GO:1990459)