Motif ID: Hoxa10

Z-value: 0.758


Transcription factors associated with Hoxa10:

Gene SymbolEntrez IDGene Name
Hoxa10 ENSMUSG00000000938.11 Hoxa10



Activity profile for motif Hoxa10.

activity profile for motif Hoxa10


Sorted Z-values histogram for motif Hoxa10

Sorted Z-values for motif Hoxa10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa10

PNG image of the network

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Top targets:


Showing 1 to 20 of 165 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_102010138 5.783 ENSMUST00000066187.4
 Nhlh2
nescient helix loop helix 2
chr11_+_44617310 4.871 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
 Ebf1


early B cell factor 1


chr8_+_106935720 4.750 ENSMUST00000047425.3
 Sntb2
syntrophin, basic 2
chr6_+_34354119 3.528 ENSMUST00000038406.6
 Akr1b8
aldo-keto reductase family 1, member B8
chr3_+_67892189 3.447 ENSMUST00000063263.3
 Iqcj
IQ motif containing J
chr17_+_29093763 3.288 ENSMUST00000023829.6
 Cdkn1a
cyclin-dependent kinase inhibitor 1A (P21)
chr13_-_99516537 3.055 ENSMUST00000064762.4
 Map1b
microtubule-associated protein 1B
chr5_-_131616599 2.645 ENSMUST00000161804.1
 Auts2
autism susceptibility candidate 2
chr11_-_42000284 2.342 ENSMUST00000109292.2
ENSMUST00000109290.1
 Gabrg2

gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

chr1_+_66321708 2.299 ENSMUST00000114013.1
 Map2
microtubule-associated protein 2
chr19_+_4711153 2.290 ENSMUST00000008991.6
 Sptbn2
spectrin beta, non-erythrocytic 2
chr1_-_89933290 2.270 ENSMUST00000036954.7
 Gbx2
gastrulation brain homeobox 2
chr3_-_123672321 2.261 ENSMUST00000172537.1
ENSMUST00000029602.6
 Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3

chr8_+_58912257 2.249 ENSMUST00000160055.1
 BC030500
cDNA sequence BC030500
chr8_-_33747724 2.068 ENSMUST00000179364.1
 Smim18
small integral membrane protein 18
chr6_-_3494587 2.058 ENSMUST00000049985.8
 Hepacam2
HEPACAM family member 2
chr6_-_99028874 2.034 ENSMUST00000154163.2
 Foxp1
forkhead box P1
chr5_-_123666682 2.002 ENSMUST00000149410.1
 Clip1
CAP-GLY domain containing linker protein 1
chr4_+_100776664 1.919 ENSMUST00000030257.8
ENSMUST00000097955.2
 Cachd1

cache domain containing 1

chr6_-_99044414 1.914 ENSMUST00000177507.1
ENSMUST00000123992.1
 Foxp1

forkhead box P1


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 5.8 GO:0007617 mating behavior(GO:0007617) multi-organism reproductive behavior(GO:0044705)
0.2 4.6 GO:0021692 cerebellar Purkinje cell layer morphogenesis(GO:0021692)
0.5 3.9 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
1.2 3.5 GO:0016095 polyprenol catabolic process(GO:0016095) terpenoid catabolic process(GO:0016115) primary alcohol catabolic process(GO:0034310)
1.1 3.4 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.4 3.3 GO:0071493 cellular response to UV-B(GO:0071493) replicative senescence(GO:0090399)
0.2 3.1 GO:0061162 establishment of monopolar cell polarity(GO:0061162)
0.2 2.7 GO:0046069 cGMP catabolic process(GO:0046069)
0.9 2.6 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.3 2.3 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.3 2.3 GO:0071420 cellular response to histamine(GO:0071420)
0.0 2.3 GO:0021954 central nervous system neuron development(GO:0021954)
0.7 2.2 GO:2000562 negative regulation of interferon-gamma secretion(GO:1902714) negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 2.1 GO:0051297 centrosome organization(GO:0051297)
0.5 2.0 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.0 1.9 GO:0008203 cholesterol metabolic process(GO:0008203)
0.3 1.8 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 1.7 GO:0007638 mechanosensory behavior(GO:0007638)
0.0 1.6 GO:0048741 skeletal muscle fiber development(GO:0048741)
0.1 1.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 6.6 GO:0005925 focal adhesion(GO:0005925)
1.1 3.4 GO:0033193 Lsd1/2 complex(GO:0033193)
1.1 3.3 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 3.1 GO:0043196 varicosity(GO:0043196)
0.4 2.3 GO:0008091 spectrin(GO:0008091)
0.3 2.3 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.1 2.3 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 2.3 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 2.1 GO:0030496 midbody(GO:0030496)
0.2 2.0 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 1.8 GO:0043204 perikaryon(GO:0043204)
0.0 1.7 GO:0032420 stereocilium(GO:0032420)
0.5 1.6 GO:0044299 C-fiber(GO:0044299)
0.1 1.3 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 1.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.1 GO:0070469 respiratory chain(GO:0070469)
0.0 0.9 GO:0016363 nuclear matrix(GO:0016363)
0.1 0.8 GO:0044308 axonal spine(GO:0044308)
0.1 0.8 GO:0000164 protein phosphatase type 1 complex(GO:0000164)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 56 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.7 5.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 5.3 GO:0005516 calmodulin binding(GO:0005516)
0.3 4.9 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.0 3.9 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.6 3.5 GO:0001758 retinal dehydrogenase activity(GO:0001758)
0.1 3.4 GO:0070888 E-box binding(GO:0070888)
0.2 3.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.4 2.7 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.3 2.3 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 2.3 GO:0050692 DBD domain binding(GO:0050692)
0.1 2.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 2.3 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.4 2.2 GO:0016936 galactoside binding(GO:0016936)
0.0 2.1 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 2.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 1.9 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.1 1.8 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 1.7 GO:0003725 double-stranded RNA binding(GO:0003725)
0.1 1.6 GO:1905030 voltage-gated sodium channel activity(GO:0005248) voltage-gated ion channel activity involved in regulation of postsynaptic membrane potential(GO:1905030)