Motif ID: Hoxa11_Hoxc12

Z-value: 1.099

Transcription factors associated with Hoxa11_Hoxc12:

Gene SymbolEntrez IDGene Name
Hoxa11 ENSMUSG00000038210.9 Hoxa11
Hoxc12 ENSMUSG00000050328.2 Hoxc12



Activity profile for motif Hoxa11_Hoxc12.

activity profile for motif Hoxa11_Hoxc12


Sorted Z-values histogram for motif Hoxa11_Hoxc12

Sorted Z-values for motif Hoxa11_Hoxc12



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa11_Hoxc12

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 123 entries
PromoterScoreRefseqGene SymbolGene Name
chr17_+_35076902 21.598 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
 Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr1_-_56978534 14.935 ENSMUST00000177282.1
 Satb2
special AT-rich sequence binding protein 2
chr1_+_43730593 12.132 ENSMUST00000027217.8
 1500015O10Rik
RIKEN cDNA 1500015O10 gene
chr1_+_178529113 9.255 ENSMUST00000161017.1
 Kif26b
kinesin family member 26B
chr6_-_55681257 8.555 ENSMUST00000044767.8
 Neurod6
neurogenic differentiation 6
chr2_+_28205648 8.044 ENSMUST00000102879.3
ENSMUST00000028177.4
 Olfm1

olfactomedin 1

chr14_+_80000292 7.038 ENSMUST00000088735.3
 Olfm4
olfactomedin 4
chr13_+_16014457 6.946 ENSMUST00000164993.1
 Inhba
inhibin beta-A
chr6_+_108213086 6.564 ENSMUST00000032192.6
 Itpr1
inositol 1,4,5-trisphosphate receptor 1
chr17_+_8283762 5.710 ENSMUST00000155364.1
ENSMUST00000046754.8
ENSMUST00000124023.1
 Mpc1


mitochondrial pyruvate carrier 1


chr16_-_57231434 5.605 ENSMUST00000023431.6
 Tbc1d23
TBC1 domain family, member 23
chr15_-_43869993 5.579 ENSMUST00000067469.4
 Tmem74
transmembrane protein 74
chr14_+_27622433 5.527 ENSMUST00000090302.5
 Erc2
ELKS/RAB6-interacting/CAST family member 2
chr16_-_45408955 5.486 ENSMUST00000163230.1
 Cd200
CD200 antigen
chr18_+_69346143 5.059 ENSMUST00000114980.1
 Tcf4
transcription factor 4
chr9_-_55919605 4.653 ENSMUST00000037408.8
 Scaper
S phase cyclin A-associated protein in the ER
chr16_-_74411776 4.482 ENSMUST00000116586.2
 Robo2
roundabout homolog 2 (Drosophila)
chr18_-_43393346 4.339 ENSMUST00000025379.7
 Dpysl3
dihydropyrimidinase-like 3
chr11_-_115628125 4.147 ENSMUST00000155709.1
ENSMUST00000021089.4
 Slc25a19

solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19

chr17_+_6270475 4.116 ENSMUST00000088940.4
 Tmem181a
transmembrane protein 181A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 57 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.8 21.6 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.9 14.9 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
1.5 12.1 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 11.9 GO:0098792 xenophagy(GO:0098792)
3.1 9.3 GO:0072092 ureteric bud invasion(GO:0072092)
0.5 8.6 GO:0021542 dentate gyrus development(GO:0021542)
0.7 8.0 GO:0023041 neuronal signal transduction(GO:0023041)
0.2 7.0 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
1.4 6.9 GO:0042636 negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279)
1.1 6.6 GO:0042045 epithelial fluid transport(GO:0042045)
1.4 5.7 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 5.6 GO:0032755 positive regulation of interleukin-6 production(GO:0032755)
0.3 5.5 GO:0043030 regulation of macrophage activation(GO:0043030)
0.0 5.3 GO:0006914 autophagy(GO:0006914)
0.5 5.1 GO:0042118 endothelial cell activation(GO:0042118)
0.1 4.8 GO:0001919 regulation of receptor recycling(GO:0001919)
1.5 4.5 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.3 4.3 GO:0051764 actin crosslink formation(GO:0051764)
1.4 4.1 GO:0009405 pathogenesis(GO:0009405)
0.0 3.6 GO:0031032 actomyosin structure organization(GO:0031032)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 18.0 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 17.4 GO:0005743 mitochondrial inner membrane(GO:0005743)
0.0 10.9 GO:0031410 cytoplasmic vesicle(GO:0031410)
0.2 8.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 7.2 GO:0005871 kinesin complex(GO:0005871)
0.5 7.0 GO:0042581 specific granule(GO:0042581)
2.3 6.9 GO:0043512 inhibin A complex(GO:0043512)
2.2 6.6 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 5.5 GO:0048786 presynaptic active zone(GO:0048786)
0.1 5.5 GO:0005913 cell-cell adherens junction(GO:0005913)
0.4 4.8 GO:0043083 synaptic cleft(GO:0043083)
0.1 4.6 GO:0032587 ruffle membrane(GO:0032587)
0.1 4.5 GO:0030673 axolemma(GO:0030673)
0.0 4.4 GO:0000790 nuclear chromatin(GO:0000790)
0.1 4.3 GO:0031941 filamentous actin(GO:0031941)
0.0 2.9 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 2.7 GO:0030175 filopodium(GO:0030175)
0.2 2.5 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.8 2.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.9 GO:0045095 keratin filament(GO:0045095)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 46 entries
Log-likelihood per target Total log-likelihoodTermDescription
7.2 21.6 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.0 10.4 GO:0003682 chromatin binding(GO:0003682)
0.6 9.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 8.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.1 7.0 GO:0045296 cadherin binding(GO:0045296)
0.0 7.0 GO:0003735 structural constituent of ribosome(GO:0003735)
1.2 6.9 GO:0070699 type II activin receptor binding(GO:0070699)
2.2 6.6 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.0 5.9 GO:0030165 PDZ domain binding(GO:0030165)
1.4 5.7 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 5.5 GO:0050839 cell adhesion molecule binding(GO:0050839)
1.3 5.1 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 5.0 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.7 4.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.0 4.8 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.2 4.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.5 4.5 GO:0008046 axon guidance receptor activity(GO:0008046)
1.1 4.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.5 4.1 GO:0015643 toxic substance binding(GO:0015643)
0.0 3.8 GO:0008017 microtubule binding(GO:0008017)