Motif ID: Hoxa13
Z-value: 0.702
Transcription factors associated with Hoxa13:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hoxa13 | ENSMUSG00000038203.12 | Hoxa13 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.6 | 4.8 | GO:0060769 | positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) kidney smooth muscle tissue development(GO:0072194) negative regulation of dopaminergic neuron differentiation(GO:1904339) |
| 0.9 | 3.7 | GO:0035606 | peptidyl-cysteine S-trans-nitrosylation(GO:0035606) |
| 0.9 | 3.5 | GO:0006526 | arginine biosynthetic process(GO:0006526) |
| 0.7 | 2.2 | GO:0036388 | pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299) |
| 0.7 | 2.2 | GO:0006269 | DNA replication, synthesis of RNA primer(GO:0006269) |
| 0.7 | 3.4 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 0.7 | 2.6 | GO:0000707 | meiotic DNA recombinase assembly(GO:0000707) |
| 0.6 | 2.4 | GO:0090324 | negative regulation of oxidative phosphorylation(GO:0090324) |
| 0.6 | 2.3 | GO:0002337 | B-1a B cell differentiation(GO:0002337) |
| 0.5 | 2.4 | GO:0035262 | gonad morphogenesis(GO:0035262) |
| 0.5 | 1.9 | GO:0033128 | negative regulation of histone phosphorylation(GO:0033128) |
| 0.4 | 1.3 | GO:0006106 | fumarate metabolic process(GO:0006106) |
| 0.4 | 1.7 | GO:0006529 | asparagine biosynthetic process(GO:0006529) |
| 0.4 | 1.2 | GO:1903225 | negative regulation of endodermal cell differentiation(GO:1903225) |
| 0.4 | 1.7 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 0.4 | 3.2 | GO:0035726 | common myeloid progenitor cell proliferation(GO:0035726) |
| 0.4 | 2.0 | GO:0097475 | motor neuron migration(GO:0097475) spinal cord motor neuron migration(GO:0097476) |
| 0.4 | 1.6 | GO:0006166 | purine ribonucleoside salvage(GO:0006166) |
| 0.4 | 1.5 | GO:0003347 | epicardial cell to mesenchymal cell transition(GO:0003347) |
| 0.4 | 1.8 | GO:0006177 | GMP biosynthetic process(GO:0006177) |
| 0.4 | 1.1 | GO:0008594 | photoreceptor cell morphogenesis(GO:0008594) |
| 0.4 | 1.1 | GO:0010986 | complement receptor mediated signaling pathway(GO:0002430) GPI anchor release(GO:0006507) positive regulation of lipoprotein particle clearance(GO:0010986) |
| 0.3 | 2.2 | GO:0001842 | neural fold formation(GO:0001842) |
| 0.3 | 1.0 | GO:0006597 | spermine biosynthetic process(GO:0006597) |
| 0.3 | 0.9 | GO:0070269 | pyroptosis(GO:0070269) |
| 0.3 | 0.9 | GO:0032058 | positive regulation of translational initiation in response to stress(GO:0032058) |
| 0.3 | 3.6 | GO:1903504 | regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504) |
| 0.3 | 0.8 | GO:0045472 | response to ether(GO:0045472) |
| 0.3 | 1.3 | GO:0046864 | retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143) |
| 0.3 | 5.1 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
| 0.2 | 1.0 | GO:0072362 | regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362) |
| 0.2 | 1.9 | GO:0018344 | protein geranylgeranylation(GO:0018344) |
| 0.2 | 1.1 | GO:0060467 | negative regulation of fertilization(GO:0060467) |
| 0.2 | 1.5 | GO:0007320 | insemination(GO:0007320) |
| 0.2 | 1.9 | GO:0000972 | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972) |
| 0.2 | 0.6 | GO:0002314 | germinal center B cell differentiation(GO:0002314) |
| 0.2 | 0.6 | GO:0060126 | somatotropin secreting cell differentiation(GO:0060126) |
| 0.2 | 0.6 | GO:0035790 | platelet-derived growth factor receptor-alpha signaling pathway(GO:0035790) |
| 0.2 | 0.8 | GO:0032511 | late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511) protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328) |
| 0.2 | 1.2 | GO:0035372 | protein localization to microtubule(GO:0035372) |
| 0.2 | 1.2 | GO:0021631 | optic nerve morphogenesis(GO:0021631) |
| 0.2 | 0.8 | GO:1903463 | mitotic cell cycle phase(GO:0098763) regulation of mitotic cell cycle DNA replication(GO:1903463) |
| 0.2 | 0.6 | GO:0002295 | T-helper cell lineage commitment(GO:0002295) |
| 0.2 | 0.9 | GO:0046598 | positive regulation of viral entry into host cell(GO:0046598) |
| 0.2 | 2.6 | GO:0090308 | regulation of methylation-dependent chromatin silencing(GO:0090308) |
| 0.2 | 0.7 | GO:0018242 | protein O-linked glycosylation via serine(GO:0018242) |
| 0.2 | 1.6 | GO:0042538 | hyperosmotic salinity response(GO:0042538) |
| 0.2 | 1.0 | GO:0043137 | DNA replication, removal of RNA primer(GO:0043137) |
| 0.2 | 1.2 | GO:0021555 | midbrain-hindbrain boundary morphogenesis(GO:0021555) |
| 0.2 | 2.7 | GO:0051451 | myoblast migration(GO:0051451) |
| 0.2 | 0.5 | GO:0019441 | tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) quinolinate biosynthetic process(GO:0019805) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189) |
| 0.2 | 1.3 | GO:0032625 | interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619) |
| 0.2 | 0.6 | GO:0090336 | positive regulation of brown fat cell differentiation(GO:0090336) |
| 0.2 | 3.0 | GO:0034643 | establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497) |
| 0.2 | 0.6 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.1 | 2.1 | GO:0060252 | positive regulation of glial cell proliferation(GO:0060252) |
| 0.1 | 0.8 | GO:1903887 | motile primary cilium assembly(GO:1903887) |
| 0.1 | 1.1 | GO:0031848 | protection from non-homologous end joining at telomere(GO:0031848) |
| 0.1 | 0.9 | GO:0014816 | skeletal muscle satellite cell differentiation(GO:0014816) |
| 0.1 | 2.3 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.1 | 0.5 | GO:1903237 | negative regulation of leukocyte tethering or rolling(GO:1903237) |
| 0.1 | 0.5 | GO:0035878 | nail development(GO:0035878) |
| 0.1 | 0.6 | GO:0071894 | histone H2B conserved C-terminal lysine ubiquitination(GO:0071894) |
| 0.1 | 0.5 | GO:0006407 | rRNA export from nucleus(GO:0006407) |
| 0.1 | 1.1 | GO:0006228 | UTP biosynthetic process(GO:0006228) |
| 0.1 | 1.4 | GO:0019985 | translesion synthesis(GO:0019985) |
| 0.1 | 0.8 | GO:0009162 | nucleoside monophosphate catabolic process(GO:0009125) deoxyribonucleoside monophosphate metabolic process(GO:0009162) |
| 0.1 | 3.5 | GO:0006270 | DNA replication initiation(GO:0006270) |
| 0.1 | 1.1 | GO:0000290 | deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) |
| 0.1 | 0.7 | GO:0010571 | positive regulation of nuclear cell cycle DNA replication(GO:0010571) |
| 0.1 | 0.7 | GO:2000767 | positive regulation of cytoplasmic translation(GO:2000767) |
| 0.1 | 0.3 | GO:2000314 | negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314) |
| 0.1 | 0.2 | GO:0060129 | thyroid-stimulating hormone-secreting cell differentiation(GO:0060129) |
| 0.1 | 1.1 | GO:0032464 | positive regulation of protein homooligomerization(GO:0032464) |
| 0.1 | 0.2 | GO:1990253 | cellular response to leucine starvation(GO:1990253) |
| 0.1 | 5.3 | GO:0010501 | RNA secondary structure unwinding(GO:0010501) |
| 0.1 | 1.4 | GO:0010388 | cullin deneddylation(GO:0010388) |
| 0.1 | 0.3 | GO:2000686 | regulation of rubidium ion transmembrane transporter activity(GO:2000686) |
| 0.1 | 0.7 | GO:0090400 | stress-induced premature senescence(GO:0090400) |
| 0.1 | 0.3 | GO:0001803 | antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805) |
| 0.1 | 1.0 | GO:0060501 | positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501) |
| 0.1 | 0.4 | GO:0006167 | AMP biosynthetic process(GO:0006167) |
| 0.1 | 0.8 | GO:0002536 | respiratory burst involved in inflammatory response(GO:0002536) |
| 0.1 | 0.3 | GO:1904211 | membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211) |
| 0.1 | 1.3 | GO:0051382 | kinetochore assembly(GO:0051382) |
| 0.1 | 0.7 | GO:0010225 | response to UV-C(GO:0010225) |
| 0.1 | 1.8 | GO:0034063 | stress granule assembly(GO:0034063) |
| 0.1 | 6.7 | GO:0006261 | DNA-dependent DNA replication(GO:0006261) |
| 0.1 | 0.7 | GO:0050957 | equilibrioception(GO:0050957) |
| 0.1 | 1.9 | GO:0040034 | regulation of development, heterochronic(GO:0040034) |
| 0.1 | 1.0 | GO:0043252 | sodium-independent organic anion transport(GO:0043252) |
| 0.1 | 0.8 | GO:0000059 | protein import into nucleus, docking(GO:0000059) ribosomal protein import into nucleus(GO:0006610) |
| 0.1 | 0.7 | GO:0006020 | inositol metabolic process(GO:0006020) |
| 0.1 | 0.2 | GO:0044828 | negative regulation by host of viral genome replication(GO:0044828) |
| 0.1 | 2.2 | GO:0006826 | iron ion transport(GO:0006826) |
| 0.1 | 1.4 | GO:0072698 | protein localization to microtubule cytoskeleton(GO:0072698) |
| 0.1 | 0.9 | GO:0003351 | epithelial cilium movement(GO:0003351) |
| 0.1 | 0.4 | GO:0006685 | sphingomyelin catabolic process(GO:0006685) |
| 0.0 | 1.3 | GO:0045747 | positive regulation of Notch signaling pathway(GO:0045747) |
| 0.0 | 2.1 | GO:0006493 | protein O-linked glycosylation(GO:0006493) |
| 0.0 | 0.1 | GO:1990414 | replication-born double-strand break repair via sister chromatid exchange(GO:1990414) |
| 0.0 | 2.2 | GO:0021884 | forebrain neuron development(GO:0021884) |
| 0.0 | 0.5 | GO:0000729 | DNA double-strand break processing(GO:0000729) |
| 0.0 | 2.2 | GO:0002066 | columnar/cuboidal epithelial cell development(GO:0002066) |
| 0.0 | 0.8 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
| 0.0 | 1.8 | GO:1902476 | chloride transmembrane transport(GO:1902476) |
| 0.0 | 0.3 | GO:0048318 | axial mesoderm development(GO:0048318) |
| 0.0 | 0.6 | GO:0042640 | anagen(GO:0042640) |
| 0.0 | 0.3 | GO:0046502 | uroporphyrinogen III metabolic process(GO:0046502) |
| 0.0 | 1.5 | GO:0048599 | oocyte development(GO:0048599) |
| 0.0 | 0.2 | GO:0035426 | extracellular matrix-cell signaling(GO:0035426) |
| 0.0 | 0.3 | GO:0061635 | regulation of protein complex stability(GO:0061635) |
| 0.0 | 0.6 | GO:0006895 | Golgi to endosome transport(GO:0006895) |
| 0.0 | 0.3 | GO:0021869 | forebrain ventricular zone progenitor cell division(GO:0021869) |
| 0.0 | 0.3 | GO:0000395 | mRNA 5'-splice site recognition(GO:0000395) |
| 0.0 | 0.2 | GO:0033136 | serine phosphorylation of STAT3 protein(GO:0033136) |
| 0.0 | 0.5 | GO:0010569 | regulation of double-strand break repair via homologous recombination(GO:0010569) |
| 0.0 | 0.6 | GO:0030574 | collagen catabolic process(GO:0030574) |
| 0.0 | 0.2 | GO:0008616 | queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116) |
| 0.0 | 0.5 | GO:0045947 | negative regulation of translational initiation(GO:0045947) |
| 0.0 | 0.3 | GO:0018230 | peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231) |
| 0.0 | 0.2 | GO:0036297 | interstrand cross-link repair(GO:0036297) |
| 0.0 | 0.5 | GO:0009083 | branched-chain amino acid catabolic process(GO:0009083) |
| 0.0 | 0.5 | GO:0070816 | phosphorylation of RNA polymerase II C-terminal domain(GO:0070816) |
| 0.0 | 0.5 | GO:0046685 | response to arsenic-containing substance(GO:0046685) |
| 0.0 | 0.9 | GO:0007608 | sensory perception of smell(GO:0007608) |
| 0.0 | 0.6 | GO:0051127 | positive regulation of actin nucleation(GO:0051127) |
| 0.0 | 0.4 | GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway(GO:0038063) |
| 0.0 | 0.4 | GO:0046697 | decidualization(GO:0046697) |
| 0.0 | 0.1 | GO:0070537 | histone H2A K63-linked deubiquitination(GO:0070537) |
| 0.0 | 1.4 | GO:0070303 | negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303) |
| 0.0 | 0.1 | GO:0018002 | N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920) |
| 0.0 | 0.1 | GO:0043490 | malate-aspartate shuttle(GO:0043490) |
| 0.0 | 0.8 | GO:0003301 | physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049) |
| 0.0 | 0.3 | GO:0006706 | steroid catabolic process(GO:0006706) |
| 0.0 | 0.7 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.0 | 0.6 | GO:0031571 | mitotic G1 DNA damage checkpoint(GO:0031571) |
| 0.0 | 0.2 | GO:0042136 | neurotransmitter biosynthetic process(GO:0042136) |
| 0.0 | 1.5 | GO:0008543 | fibroblast growth factor receptor signaling pathway(GO:0008543) |
| 0.0 | 0.2 | GO:0006370 | 7-methylguanosine mRNA capping(GO:0006370) |
| 0.0 | 0.6 | GO:0034724 | DNA replication-independent nucleosome assembly(GO:0006336) DNA replication-independent nucleosome organization(GO:0034724) |
| 0.0 | 1.1 | GO:0043087 | regulation of GTPase activity(GO:0043087) |
| 0.0 | 0.5 | GO:0015813 | L-glutamate transport(GO:0015813) |
| 0.0 | 1.3 | GO:0072661 | protein targeting to plasma membrane(GO:0072661) |
| 0.0 | 1.0 | GO:0006406 | mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427) |
| 0.0 | 0.1 | GO:0098700 | aminergic neurotransmitter loading into synaptic vesicle(GO:0015842) neurotransmitter loading into synaptic vesicle(GO:0098700) |
| 0.0 | 1.2 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.0 | 1.0 | GO:0042073 | intraciliary transport(GO:0042073) protein transport along microtubule(GO:0098840) |
| 0.0 | 0.3 | GO:0060716 | labyrinthine layer blood vessel development(GO:0060716) |
| 0.0 | 1.1 | GO:0051489 | regulation of filopodium assembly(GO:0051489) |
| 0.0 | 0.2 | GO:0006013 | mannose metabolic process(GO:0006013) |
| 0.0 | 0.0 | GO:0097680 | double-strand break repair via classical nonhomologous end joining(GO:0097680) |
| 0.0 | 0.6 | GO:0035058 | nonmotile primary cilium assembly(GO:0035058) |
| 0.0 | 0.6 | GO:0045197 | establishment or maintenance of epithelial cell apical/basal polarity(GO:0045197) |
| 0.0 | 1.5 | GO:0090630 | activation of GTPase activity(GO:0090630) |
| 0.0 | 0.3 | GO:0016226 | iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163) |
| 0.0 | 0.3 | GO:0035493 | SNARE complex assembly(GO:0035493) |
| 0.0 | 0.3 | GO:0001522 | pseudouridine synthesis(GO:0001522) |
| 0.0 | 0.2 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.0 | 0.3 | GO:0043984 | histone H4-K16 acetylation(GO:0043984) |
| 0.0 | 0.7 | GO:0006414 | translational elongation(GO:0006414) |
| 0.0 | 5.8 | GO:0016055 | Wnt signaling pathway(GO:0016055) cell-cell signaling by wnt(GO:0198738) |
| 0.0 | 0.4 | GO:0043171 | peptide catabolic process(GO:0043171) |
| 0.0 | 0.8 | GO:0007368 | determination of left/right symmetry(GO:0007368) |
| 0.0 | 0.8 | GO:0006749 | glutathione metabolic process(GO:0006749) |
| 0.0 | 0.9 | GO:0009060 | aerobic respiration(GO:0009060) |
| 0.0 | 0.3 | GO:0035335 | peptidyl-tyrosine dephosphorylation(GO:0035335) |
| 0.0 | 0.2 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
| 0.0 | 0.0 | GO:0045409 | negative regulation of interleukin-6 biosynthetic process(GO:0045409) |
| 0.0 | 0.4 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.0 | 0.2 | GO:0032967 | positive regulation of collagen biosynthetic process(GO:0032967) |
| 0.0 | 0.4 | GO:0000725 | double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725) |
| 0.0 | 0.2 | GO:0007602 | phototransduction(GO:0007602) |
| 0.0 | 0.4 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 0.0 | 1.4 | GO:0006626 | protein targeting to mitochondrion(GO:0006626) |
| 0.0 | 1.2 | GO:0019827 | stem cell population maintenance(GO:0019827) |
| 0.0 | 0.9 | GO:0008637 | apoptotic mitochondrial changes(GO:0008637) |
| 0.0 | 0.6 | GO:0042274 | ribosomal small subunit biogenesis(GO:0042274) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.3 | 6.5 | GO:0008623 | CHRAC(GO:0008623) |
| 0.7 | 2.2 | GO:0036387 | nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387) |
| 0.6 | 2.2 | GO:0090537 | CERF complex(GO:0090537) |
| 0.5 | 3.7 | GO:0097452 | GAIT complex(GO:0097452) |
| 0.5 | 2.6 | GO:0033063 | Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063) |
| 0.4 | 1.2 | GO:0005588 | collagen type V trimer(GO:0005588) |
| 0.4 | 2.5 | GO:0001674 | female germ cell nucleus(GO:0001674) |
| 0.4 | 1.9 | GO:0005968 | Rab-protein geranylgeranyltransferase complex(GO:0005968) |
| 0.3 | 1.5 | GO:0000015 | phosphopyruvate hydratase complex(GO:0000015) |
| 0.3 | 0.9 | GO:0071920 | cleavage body(GO:0071920) |
| 0.3 | 1.1 | GO:0060187 | cell pole(GO:0060187) |
| 0.3 | 3.0 | GO:0031080 | nuclear pore outer ring(GO:0031080) |
| 0.3 | 0.8 | GO:0000814 | ESCRT II complex(GO:0000814) |
| 0.3 | 1.6 | GO:0000444 | MIS12/MIND type complex(GO:0000444) |
| 0.2 | 0.9 | GO:0061702 | inflammasome complex(GO:0061702) |
| 0.2 | 2.6 | GO:0097431 | mitotic spindle pole(GO:0097431) |
| 0.2 | 0.6 | GO:0005896 | interleukin-6 receptor complex(GO:0005896) |
| 0.2 | 1.3 | GO:0097197 | tetraspanin-enriched microdomain(GO:0097197) |
| 0.2 | 0.5 | GO:1990393 | 3M complex(GO:1990393) |
| 0.2 | 1.0 | GO:0032299 | ribonuclease H2 complex(GO:0032299) |
| 0.2 | 2.3 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.2 | 0.5 | GO:0002944 | cyclin K-CDK12 complex(GO:0002944) |
| 0.1 | 0.4 | GO:0034673 | inhibin-betaglycan-ActRII complex(GO:0034673) |
| 0.1 | 0.4 | GO:0005658 | alpha DNA polymerase:primase complex(GO:0005658) |
| 0.1 | 3.0 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.1 | 1.5 | GO:0046930 | pore complex(GO:0046930) |
| 0.1 | 0.7 | GO:0005853 | eukaryotic translation elongation factor 1 complex(GO:0005853) |
| 0.1 | 1.6 | GO:0045239 | tricarboxylic acid cycle enzyme complex(GO:0045239) |
| 0.1 | 1.6 | GO:0005682 | U5 snRNP(GO:0005682) |
| 0.1 | 0.5 | GO:0030289 | protein phosphatase 4 complex(GO:0030289) |
| 0.1 | 1.1 | GO:0016442 | RISC complex(GO:0016442) RNAi effector complex(GO:0031332) |
| 0.1 | 0.4 | GO:0005587 | collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651) |
| 0.1 | 1.9 | GO:0030894 | replisome(GO:0030894) |
| 0.1 | 1.0 | GO:0042788 | polysomal ribosome(GO:0042788) |
| 0.1 | 0.2 | GO:0038045 | large latent transforming growth factor-beta complex(GO:0038045) |
| 0.1 | 6.5 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.1 | 0.3 | GO:0072487 | MSL complex(GO:0072487) |
| 0.1 | 1.1 | GO:0043220 | Schmidt-Lanterman incisure(GO:0043220) |
| 0.1 | 0.7 | GO:0034518 | mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518) |
| 0.1 | 0.3 | GO:0070820 | tertiary granule(GO:0070820) |
| 0.0 | 0.5 | GO:0016272 | prefoldin complex(GO:0016272) |
| 0.0 | 2.2 | GO:0005844 | polysome(GO:0005844) |
| 0.0 | 0.7 | GO:0032156 | septin cytoskeleton(GO:0032156) |
| 0.0 | 0.8 | GO:0031512 | motile primary cilium(GO:0031512) |
| 0.0 | 0.6 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.0 | 1.0 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 1.1 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
| 0.0 | 0.7 | GO:0045263 | proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263) |
| 0.0 | 0.2 | GO:0016602 | CCAAT-binding factor complex(GO:0016602) |
| 0.0 | 0.5 | GO:0030056 | hemidesmosome(GO:0030056) |
| 0.0 | 2.4 | GO:0016459 | myosin complex(GO:0016459) |
| 0.0 | 0.3 | GO:0000243 | commitment complex(GO:0000243) |
| 0.0 | 5.6 | GO:0036464 | cytoplasmic ribonucleoprotein granule(GO:0036464) |
| 0.0 | 1.0 | GO:0032391 | photoreceptor connecting cilium(GO:0032391) |
| 0.0 | 2.5 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 1.1 | GO:0060077 | inhibitory synapse(GO:0060077) |
| 0.0 | 0.4 | GO:0043596 | nuclear replication fork(GO:0043596) |
| 0.0 | 0.4 | GO:0042555 | MCM complex(GO:0042555) |
| 0.0 | 1.4 | GO:0008180 | COP9 signalosome(GO:0008180) |
| 0.0 | 2.0 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 0.6 | GO:0042470 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.0 | 1.5 | GO:0005871 | kinesin complex(GO:0005871) |
| 0.0 | 0.9 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 3.7 | GO:0043296 | apical junction complex(GO:0043296) |
| 0.0 | 0.3 | GO:0044322 | endoplasmic reticulum quality control compartment(GO:0044322) |
| 0.0 | 0.1 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.0 | 2.0 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 1.3 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.0 | 0.2 | GO:0031209 | SCAR complex(GO:0031209) |
| 0.0 | 0.6 | GO:0030686 | 90S preribosome(GO:0030686) |
| 0.0 | 0.3 | GO:0005736 | DNA-directed RNA polymerase II, core complex(GO:0005665) DNA-directed RNA polymerase I complex(GO:0005736) |
| 0.0 | 0.1 | GO:0031415 | NatA complex(GO:0031415) |
| 0.0 | 4.4 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.0 | 0.7 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 1.1 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 2.5 | GO:0005813 | centrosome(GO:0005813) |
| 0.0 | 2.7 | GO:0016323 | basolateral plasma membrane(GO:0016323) |
| 0.0 | 0.1 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.0 | 0.9 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
| 0.0 | 0.1 | GO:0005677 | chromatin silencing complex(GO:0005677) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.2 | 3.7 | GO:0035605 | peptidyl-cysteine S-nitrosylase activity(GO:0035605) |
| 1.0 | 4.8 | GO:0005113 | patched binding(GO:0005113) |
| 0.9 | 2.6 | GO:0044729 | hemi-methylated DNA-binding(GO:0044729) |
| 0.9 | 3.5 | GO:0016812 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812) |
| 0.5 | 1.6 | GO:0004731 | purine-nucleoside phosphorylase activity(GO:0004731) |
| 0.5 | 3.4 | GO:0032453 | histone demethylase activity (H3-K4 specific)(GO:0032453) |
| 0.5 | 1.8 | GO:0003938 | IMP dehydrogenase activity(GO:0003938) |
| 0.4 | 1.7 | GO:0004066 | asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066) |
| 0.4 | 1.5 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.4 | 1.5 | GO:0000832 | inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724) |
| 0.4 | 2.6 | GO:0000150 | recombinase activity(GO:0000150) |
| 0.3 | 1.7 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.3 | 1.9 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
| 0.3 | 5.1 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
| 0.3 | 1.7 | GO:0052630 | CTP:2,3-di-O-geranylgeranyl-sn-glycero-1-phosphate cytidyltransferase activity(GO:0043338) phospholactate guanylyltransferase activity(GO:0043814) ATP:coenzyme F420 adenylyltransferase activity(GO:0043910) UDP-N-acetylgalactosamine diphosphorylase activity(GO:0052630) |
| 0.3 | 0.9 | GO:0033677 | DNA/RNA helicase activity(GO:0033677) |
| 0.3 | 0.8 | GO:0045504 | dynein heavy chain binding(GO:0045504) |
| 0.3 | 2.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.3 | 1.3 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.2 | 1.0 | GO:0019808 | polyamine binding(GO:0019808) |
| 0.2 | 0.7 | GO:0031403 | lithium ion binding(GO:0031403) |
| 0.2 | 0.4 | GO:0017116 | single-stranded DNA-dependent ATP-dependent DNA helicase activity(GO:0017116) |
| 0.2 | 0.6 | GO:0035673 | oligopeptide transmembrane transporter activity(GO:0035673) |
| 0.2 | 3.2 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.2 | 1.2 | GO:0005005 | transmembrane-ephrin receptor activity(GO:0005005) |
| 0.2 | 0.6 | GO:0004140 | dephospho-CoA kinase activity(GO:0004140) |
| 0.2 | 0.5 | GO:0030362 | protein phosphatase type 4 regulator activity(GO:0030362) |
| 0.2 | 2.9 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.2 | 1.0 | GO:0004984 | olfactory receptor activity(GO:0004984) |
| 0.2 | 0.5 | GO:0016174 | NAD(P)H oxidase activity(GO:0016174) |
| 0.2 | 1.5 | GO:0004634 | phosphopyruvate hydratase activity(GO:0004634) |
| 0.2 | 0.5 | GO:0048045 | 4-hydroxybenzoate octaprenyltransferase activity(GO:0008412) protoheme IX farnesyltransferase activity(GO:0008495) (S)-2,3-di-O-geranylgeranylglyceryl phosphate synthase activity(GO:0043888) cadaverine aminopropyltransferase activity(GO:0043918) agmatine aminopropyltransferase activity(GO:0043919) 1,4-dihydroxy-2-naphthoate octaprenyltransferase activity(GO:0046428) trans-pentaprenyltranstransferase activity(GO:0048045) ATP dimethylallyltransferase activity(GO:0052622) ADP dimethylallyltransferase activity(GO:0052623) |
| 0.2 | 6.2 | GO:0005109 | frizzled binding(GO:0005109) |
| 0.2 | 0.9 | GO:0071074 | eukaryotic initiation factor eIF2 binding(GO:0071074) |
| 0.1 | 2.2 | GO:0016805 | dipeptidase activity(GO:0016805) |
| 0.1 | 1.3 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 0.6 | GO:0016230 | sphingomyelin phosphodiesterase activator activity(GO:0016230) |
| 0.1 | 2.8 | GO:0004653 | polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653) |
| 0.1 | 2.1 | GO:0008574 | ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574) |
| 0.1 | 1.2 | GO:0035312 | 5'-3' exodeoxyribonuclease activity(GO:0035312) |
| 0.1 | 1.0 | GO:0004523 | RNA-DNA hybrid ribonuclease activity(GO:0004523) |
| 0.1 | 0.5 | GO:0031735 | CCR10 chemokine receptor binding(GO:0031735) |
| 0.1 | 0.4 | GO:0071208 | histone pre-mRNA DCP binding(GO:0071208) |
| 0.1 | 0.4 | GO:0016262 | protein N-acetylglucosaminyltransferase activity(GO:0016262) |
| 0.1 | 1.6 | GO:0043522 | leucine zipper domain binding(GO:0043522) |
| 0.1 | 2.7 | GO:0017049 | GTP-Rho binding(GO:0017049) |
| 0.1 | 1.0 | GO:0035033 | histone deacetylase regulator activity(GO:0035033) |
| 0.1 | 1.1 | GO:0004630 | phospholipase D activity(GO:0004630) |
| 0.1 | 1.1 | GO:0050072 | m7G(5')pppN diphosphatase activity(GO:0050072) |
| 0.1 | 1.1 | GO:0008190 | eukaryotic initiation factor 4E binding(GO:0008190) |
| 0.1 | 1.1 | GO:0050692 | DBD domain binding(GO:0050692) |
| 0.1 | 0.4 | GO:0003941 | L-serine ammonia-lyase activity(GO:0003941) |
| 0.1 | 3.0 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.1 | 0.5 | GO:0038132 | neuregulin binding(GO:0038132) |
| 0.1 | 0.6 | GO:0005229 | intracellular calcium activated chloride channel activity(GO:0005229) |
| 0.1 | 0.6 | GO:0005138 | interleukin-6 receptor binding(GO:0005138) |
| 0.1 | 0.4 | GO:0004921 | interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970) |
| 0.1 | 1.0 | GO:0015347 | sodium-independent organic anion transmembrane transporter activity(GO:0015347) |
| 0.1 | 0.3 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.1 | 1.0 | GO:0044323 | retinoic acid-responsive element binding(GO:0044323) |
| 0.1 | 0.7 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.1 | 0.5 | GO:0019784 | NEDD8-specific protease activity(GO:0019784) |
| 0.1 | 0.2 | GO:0008192 | RNA guanylyltransferase activity(GO:0008192) |
| 0.1 | 0.9 | GO:0003680 | AT DNA binding(GO:0003680) |
| 0.1 | 1.6 | GO:0005092 | GDP-dissociation inhibitor activity(GO:0005092) |
| 0.1 | 0.7 | GO:0050733 | RS domain binding(GO:0050733) |
| 0.1 | 4.5 | GO:0008186 | ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186) |
| 0.1 | 0.8 | GO:0008379 | thioredoxin peroxidase activity(GO:0008379) |
| 0.1 | 0.8 | GO:0070636 | single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694) |
| 0.1 | 2.0 | GO:0001106 | RNA polymerase II transcription corepressor activity(GO:0001106) |
| 0.1 | 1.1 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.1 | 0.2 | GO:0050436 | microfibril binding(GO:0050436) |
| 0.1 | 0.7 | GO:0000400 | four-way junction DNA binding(GO:0000400) |
| 0.1 | 0.3 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.0 | 1.6 | GO:0005086 | ARF guanyl-nucleotide exchange factor activity(GO:0005086) |
| 0.0 | 0.4 | GO:0005114 | type II transforming growth factor beta receptor binding(GO:0005114) |
| 0.0 | 0.2 | GO:0019145 | aminobutyraldehyde dehydrogenase activity(GO:0019145) 4-trimethylammoniobutyraldehyde dehydrogenase activity(GO:0047105) |
| 0.0 | 0.3 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.0 | 0.2 | GO:0004784 | superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721) |
| 0.0 | 1.3 | GO:0051183 | vitamin transporter activity(GO:0051183) |
| 0.0 | 0.4 | GO:0004767 | sphingomyelin phosphodiesterase activity(GO:0004767) |
| 0.0 | 1.7 | GO:0042169 | SH2 domain binding(GO:0042169) |
| 0.0 | 1.3 | GO:0035254 | glutamate receptor binding(GO:0035254) |
| 0.0 | 0.2 | GO:0003854 | 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854) |
| 0.0 | 1.0 | GO:0051537 | 2 iron, 2 sulfur cluster binding(GO:0051537) |
| 0.0 | 0.3 | GO:0048101 | calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101) |
| 0.0 | 0.4 | GO:0050897 | cobalt ion binding(GO:0050897) |
| 0.0 | 0.2 | GO:0008479 | queuine tRNA-ribosyltransferase activity(GO:0008479) |
| 0.0 | 0.3 | GO:0031435 | mitogen-activated protein kinase kinase kinase binding(GO:0031435) |
| 0.0 | 0.1 | GO:0031752 | D5 dopamine receptor binding(GO:0031752) |
| 0.0 | 1.2 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.0 | 0.7 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
| 0.0 | 0.2 | GO:0043237 | laminin-1 binding(GO:0043237) |
| 0.0 | 3.4 | GO:0101005 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.0 | 0.6 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.0 | 0.8 | GO:0008139 | nuclear localization sequence binding(GO:0008139) |
| 0.0 | 1.5 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 0.7 | GO:0005070 | SH3/SH2 adaptor activity(GO:0005070) |
| 0.0 | 0.2 | GO:0019211 | phosphatase activator activity(GO:0019211) |
| 0.0 | 0.8 | GO:0000993 | RNA polymerase II core binding(GO:0000993) |
| 0.0 | 0.5 | GO:0044183 | protein binding involved in protein folding(GO:0044183) |
| 0.0 | 0.7 | GO:0009931 | calcium-dependent protein serine/threonine kinase activity(GO:0009931) |
| 0.0 | 0.1 | GO:1990189 | peptide-serine-N-acetyltransferase activity(GO:1990189) peptide-glutamate-N-acetyltransferase activity(GO:1990190) |
| 0.0 | 0.3 | GO:0001055 | RNA polymerase II activity(GO:0001055) |
| 0.0 | 0.3 | GO:0034951 | pivalyl-CoA mutase activity(GO:0034784) o-hydroxylaminobenzoate mutase activity(GO:0034951) lupeol synthase activity(GO:0042299) beta-amyrin synthase activity(GO:0042300) baruol synthase activity(GO:0080011) |
| 0.0 | 0.8 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.1 | GO:0036468 | aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468) |
| 0.0 | 0.7 | GO:0003746 | translation elongation factor activity(GO:0003746) |
| 0.0 | 1.7 | GO:0004252 | serine-type endopeptidase activity(GO:0004252) |
| 0.0 | 1.1 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 0.8 | GO:0032266 | phosphatidylinositol-3-phosphate binding(GO:0032266) |
| 0.0 | 0.4 | GO:0070577 | lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 1.1 | GO:0019894 | kinesin binding(GO:0019894) |
| 0.0 | 0.4 | GO:0008175 | tRNA methyltransferase activity(GO:0008175) |
| 0.0 | 0.4 | GO:0016676 | cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676) |
| 0.0 | 1.6 | GO:0030792 | methylarsonite methyltransferase activity(GO:0030792) |
| 0.0 | 0.2 | GO:0036310 | annealing helicase activity(GO:0036310) |
| 0.0 | 0.8 | GO:0070491 | repressing transcription factor binding(GO:0070491) |
| 0.0 | 0.7 | GO:0035255 | ionotropic glutamate receptor binding(GO:0035255) |
| 0.0 | 1.8 | GO:0000978 | RNA polymerase II core promoter proximal region sequence-specific DNA binding(GO:0000978) |
| 0.0 | 1.1 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 0.0 | GO:0008297 | single-stranded DNA exodeoxyribonuclease activity(GO:0008297) |
| 0.0 | 0.7 | GO:0035496 | UDP-glucose:glycoprotein glucosyltransferase activity(GO:0003980) O antigen polymerase activity(GO:0008755) lipopolysaccharide-1,6-galactosyltransferase activity(GO:0008921) cellulose synthase activity(GO:0016759) 9-phenanthrol UDP-glucuronosyltransferase activity(GO:0018715) 1-phenanthrol glycosyltransferase activity(GO:0018716) 9-phenanthrol glycosyltransferase activity(GO:0018717) 1,2-dihydroxy-phenanthrene glycosyltransferase activity(GO:0018718) phenanthrol glycosyltransferase activity(GO:0019112) alpha-1,2-galactosyltransferase activity(GO:0031278) dolichyl pyrophosphate Man7GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0033556) endogalactosaminidase activity(GO:0033931) lipopolysaccharide-1,5-galactosyltransferase activity(GO:0035496) dolichyl pyrophosphate Glc1Man9GlcNAc2 alpha-1,3-glucosyltransferase activity(GO:0042283) inositol phosphoceramide synthase activity(GO:0045140) alpha-(1->3)-fucosyltransferase activity(GO:0046920) indole-3-butyrate beta-glucosyltransferase activity(GO:0052638) salicylic acid glucosyltransferase (ester-forming) activity(GO:0052639) salicylic acid glucosyltransferase (glucoside-forming) activity(GO:0052640) benzoic acid glucosyltransferase activity(GO:0052641) chondroitin hydrolase activity(GO:0052757) dolichyl-pyrophosphate Man7GlcNAc2 alpha-1,6-mannosyltransferase activity(GO:0052824) cytokinin 9-beta-glucosyltransferase activity(GO:0080062) |
| 0.0 | 2.9 | GO:0004721 | phosphoprotein phosphatase activity(GO:0004721) |
| 0.0 | 0.8 | GO:0030507 | spectrin binding(GO:0030507) |
| 0.0 | 0.1 | GO:0030550 | acetylcholine receptor inhibitor activity(GO:0030550) |
| 0.0 | 0.6 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 0.3 | GO:0008198 | ferrous iron binding(GO:0008198) |
| 0.0 | 0.1 | GO:0030159 | receptor signaling complex scaffold activity(GO:0030159) |
| 0.0 | 0.0 | GO:0097157 | pre-mRNA intronic binding(GO:0097157) |
| 0.0 | 0.2 | GO:0019783 | ubiquitin-like protein-specific protease activity(GO:0019783) |
| 0.0 | 0.3 | GO:0019706 | protein-cysteine S-palmitoyltransferase activity(GO:0019706) |
| 0.0 | 0.1 | GO:0070530 | K63-linked polyubiquitin binding(GO:0070530) |
| 0.0 | 0.3 | GO:0035035 | histone acetyltransferase binding(GO:0035035) |
| 0.0 | 0.7 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
