Motif ID: Hoxa2

Z-value: 0.966


Transcription factors associated with Hoxa2:

Gene SymbolEntrez IDGene Name
Hoxa2 ENSMUSG00000014704.8 Hoxa2



Activity profile for motif Hoxa2.

activity profile for motif Hoxa2


Sorted Z-values histogram for motif Hoxa2

Sorted Z-values for motif Hoxa2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa2

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_139543889 10.218 ENSMUST00000174792.1
ENSMUST00000031523.8
Uncx

UNC homeobox

chr12_+_109747903 6.915 ENSMUST00000183084.1
ENSMUST00000182300.1
Mirg

miRNA containing gene

chr5_-_24527276 5.305 ENSMUST00000088311.4
Gbx1
gastrulation brain homeobox 1
chr16_-_23890805 4.757 ENSMUST00000004480.3
Sst
somatostatin
chr9_+_51621425 4.433 ENSMUST00000089534.4
Gm7293
predicted gene 7293
chr2_-_117342949 4.103 ENSMUST00000102534.4
Rasgrp1
RAS guanyl releasing protein 1
chr13_+_117220584 4.069 ENSMUST00000022242.7
Emb
embigin
chr14_-_34374617 3.980 ENSMUST00000023826.4
Sncg
synuclein, gamma
chr2_-_117342831 3.833 ENSMUST00000178884.1
Rasgrp1
RAS guanyl releasing protein 1
chr9_-_106158109 3.749 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
Glyctk



glycerate kinase



chr2_-_117342709 3.700 ENSMUST00000173541.1
ENSMUST00000172901.1
ENSMUST00000173252.1
Rasgrp1


RAS guanyl releasing protein 1


chr7_+_144838590 3.655 ENSMUST00000105898.1
Fgf3
fibroblast growth factor 3
chr8_-_87959560 3.641 ENSMUST00000109655.2
Zfp423
zinc finger protein 423
chr8_-_4779513 3.449 ENSMUST00000022945.7
Shcbp1
Shc SH2-domain binding protein 1
chr10_-_92162753 3.394 ENSMUST00000182197.1
Rmst
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr3_+_55782500 3.264 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr7_+_45163915 3.224 ENSMUST00000085374.5
Slc17a7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 7
chr10_-_96409038 3.204 ENSMUST00000179683.1
Gm20091
predicted gene, 20091
chr4_+_105790534 3.085 ENSMUST00000185012.1
Gm12728
predicted gene 12728
chr6_+_5390387 2.861 ENSMUST00000183358.1
Asb4
ankyrin repeat and SOCS box-containing 4

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 169 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 11.6 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
1.5 10.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
1.9 9.6 GO:0046864 retinol transport(GO:0034633) isoprenoid transport(GO:0046864) terpenoid transport(GO:0046865) alveolar primary septum development(GO:0061143)
1.3 5.3 GO:0097374 sensory neuron axon guidance(GO:0097374)
0.5 5.1 GO:0018065 protein-cofactor linkage(GO:0018065)
1.6 4.8 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 4.7 GO:0007067 mitotic nuclear division(GO:0007067)
0.1 4.4 GO:0006879 cellular iron ion homeostasis(GO:0006879)
1.0 4.1 GO:0032901 positive regulation of neurotrophin production(GO:0032901)
0.2 4.1 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 4.1 GO:0016525 negative regulation of angiogenesis(GO:0016525)
0.5 3.7 GO:0030916 otic vesicle formation(GO:0030916) semicircular canal morphogenesis(GO:0048752)
0.1 3.5 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.1 3.4 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
1.1 3.2 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 3.2 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.3 2.9 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 2.9 GO:0048844 artery morphogenesis(GO:0048844)
0.2 2.7 GO:0097067 negative regulation of erythrocyte differentiation(GO:0045647) cellular response to thyroid hormone stimulus(GO:0097067)
0.1 2.7 GO:0007614 short-term memory(GO:0007614)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 5.8 GO:0031262 Ndc80 complex(GO:0031262)
0.1 4.8 GO:0072562 blood microparticle(GO:0072562)
0.0 3.9 GO:0000922 spindle pole(GO:0000922)
0.1 3.8 GO:0005776 autophagosome(GO:0005776)
0.0 3.7 GO:0005643 nuclear pore(GO:0005643)
0.0 3.6 GO:0000776 kinetochore(GO:0000776)
0.2 3.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.7 2.9 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.9 2.8 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 2.8 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 2.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 2.5 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 2.4 GO:0097542 ciliary tip(GO:0097542)
0.0 2.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 2.2 GO:0070469 respiratory chain(GO:0070469)
0.0 2.1 GO:0043195 terminal bouton(GO:0043195)
0.0 2.0 GO:0005581 collagen trimer(GO:0005581)
0.0 1.9 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 1.9 GO:0043025 neuronal cell body(GO:0043025)
0.0 1.9 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 123 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 14.5 GO:0043565 sequence-specific DNA binding(GO:0043565)
1.2 12.7 GO:0019992 diacylglycerol binding(GO:0019992)
0.3 9.6 GO:0051183 vitamin transporter activity(GO:0051183)
0.3 4.8 GO:0001848 complement binding(GO:0001848)
0.0 4.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 4.2 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.5 4.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.1 3.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.1 3.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.1 3.4 GO:0042169 SH2 domain binding(GO:0042169)
1.1 3.2 GO:0005436 sodium:phosphate symporter activity(GO:0005436) sodium:inorganic phosphate symporter activity(GO:0015319)
0.1 3.0 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.9 2.8 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 2.6 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 2.6 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 2.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 2.5 GO:0019842 vitamin binding(GO:0019842)
0.1 2.3 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.4 2.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.1 2.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)