Motif ID: Hoxa3

Z-value: 0.540


Transcription factors associated with Hoxa3:

Gene SymbolEntrez IDGene Name
Hoxa3 ENSMUSG00000079560.7 Hoxa3



Activity profile for motif Hoxa3.

activity profile for motif Hoxa3


Sorted Z-values histogram for motif Hoxa3

Sorted Z-values for motif Hoxa3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa3

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_55782500 5.596 ENSMUST00000075422.4
Mab21l1
mab-21-like 1 (C. elegans)
chr2_-_168767136 5.485 ENSMUST00000029061.5
ENSMUST00000103074.1
Sall4

sal-like 4 (Drosophila)

chr17_-_70853482 5.094 ENSMUST00000118283.1
Tgif1
TGFB-induced factor homeobox 1
chr9_+_119063429 4.354 ENSMUST00000141185.1
ENSMUST00000126251.1
ENSMUST00000136561.1
Vill


villin-like


chr2_-_168767029 4.105 ENSMUST00000075044.3
Sall4
sal-like 4 (Drosophila)
chr2_+_109917639 2.946 ENSMUST00000046548.7
ENSMUST00000111037.2
Lgr4

leucine-rich repeat-containing G protein-coupled receptor 4

chr3_+_159839729 2.625 ENSMUST00000068952.5
Wls
wntless homolog (Drosophila)
chr13_-_102905740 2.606 ENSMUST00000167462.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr13_-_102906046 2.457 ENSMUST00000171791.1
Mast4
microtubule associated serine/threonine kinase family member 4
chr3_-_86548268 2.424 ENSMUST00000077524.3
Mab21l2
mab-21-like 2 (C. elegans)
chr10_+_37139558 1.646 ENSMUST00000062667.3
5930403N24Rik
RIKEN cDNA 5930403N24 gene
chr12_+_59013379 1.244 ENSMUST00000021379.7
Gemin2
gem (nuclear organelle) associated protein 2
chr10_-_37138863 1.198 ENSMUST00000092584.5
Marcks
myristoylated alanine rich protein kinase C substrate
chr17_+_17402672 1.106 ENSMUST00000115576.2
Lix1
limb expression 1 homolog (chicken)
chr5_+_138187485 0.943 ENSMUST00000110934.2
Cnpy4
canopy 4 homolog (zebrafish)
chr5_-_138187177 0.847 ENSMUST00000110937.1
ENSMUST00000139276.1
ENSMUST00000048698.7
ENSMUST00000123415.1
Taf6



TAF6 RNA polymerase II, TATA box binding protein (TBP)-associated factor



chr10_+_26772477 0.818 ENSMUST00000039557.7
Arhgap18
Rho GTPase activating protein 18
chr1_-_172027269 0.807 ENSMUST00000027837.6
ENSMUST00000111264.1
Vangl2

vang-like 2 (van gogh, Drosophila)

chr14_+_79515618 0.618 ENSMUST00000110835.1
Elf1
E74-like factor 1
chr7_-_38019505 0.611 ENSMUST00000085513.4
Uri1
URI1, prefoldin-like chaperone
chr2_+_36230426 0.343 ENSMUST00000062069.5
Ptgs1
prostaglandin-endoperoxide synthase 1
chr14_+_64589802 0.322 ENSMUST00000180610.1
A930011O12Rik
RIKEN cDNA A930011O12 gene
chr2_-_69712461 0.295 ENSMUST00000102706.3
ENSMUST00000073152.6
Fastkd1

FAST kinase domains 1

chr7_-_116038734 0.243 ENSMUST00000166877.1
Sox6
SRY-box containing gene 6
chr5_-_137531952 0.136 ENSMUST00000140139.1
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr1_-_172027251 0.119 ENSMUST00000138714.1
Vangl2
vang-like 2 (van gogh, Drosophila)
chr11_+_95384662 0.050 ENSMUST00000021243.7
ENSMUST00000146556.1
Slc35b1

solute carrier family 35, member B1

chr5_-_137531204 0.037 ENSMUST00000150063.2
Gnb2
guanine nucleotide binding protein (G protein), beta 2
chr17_+_45734506 0.014 ENSMUST00000180558.1
F630040K05Rik
RIKEN cDNA F630040K05 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 2.9 GO:0072204 cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204)
0.5 9.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 5.1 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.3 0.9 GO:0060489 establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.2 2.6 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 0.3 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 2.4 GO:0010172 embryonic body morphogenesis(GO:0010172)
0.1 4.4 GO:0051693 actin filament capping(GO:0051693)
0.0 1.1 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.6 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 1.2 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:2000741 positive regulation of mesenchymal stem cell differentiation(GO:2000741)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 5.4 GO:0043010 camera-type eye development(GO:0043010)
0.0 0.8 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0042585 germinal vesicle(GO:0042585)
0.2 0.9 GO:0060187 cell pole(GO:0060187)
0.1 1.2 GO:0032797 SMN complex(GO:0032797)
0.1 2.6 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 9.6 GO:0000792 heterochromatin(GO:0000792)
0.0 0.8 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.6 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.6 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.2 2.9 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.2 5.1 GO:0070410 co-SMAD binding(GO:0070410)
0.0 5.1 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.6 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 1.2 GO:0005080 protein kinase C binding(GO:0005080)
0.0 0.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 10.5 GO:0044212 transcription regulatory region DNA binding(GO:0044212)