Motif ID: Hoxa4

Z-value: 1.007


Transcription factors associated with Hoxa4:

Gene SymbolEntrez IDGene Name
Hoxa4 ENSMUSG00000000942.10 Hoxa4



Activity profile for motif Hoxa4.

activity profile for motif Hoxa4


Sorted Z-values histogram for motif Hoxa4

Sorted Z-values for motif Hoxa4



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_71528657 11.107 ENSMUST00000126400.1
 Dlx1
distal-less homeobox 1
chr2_+_90885860 10.863 ENSMUST00000111466.2
 C1qtnf4
C1q and tumor necrosis factor related protein 4
chr1_+_19103022 10.094 ENSMUST00000037294.7
 Tfap2d
transcription factor AP-2, delta
chr3_-_80802789 9.486 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr2_+_170731807 8.037 ENSMUST00000029075.4
 Dok5
docking protein 5
chr14_-_79771305 7.252 ENSMUST00000039568.5
 Pcdh8
protocadherin 8
chr4_+_105790534 7.078 ENSMUST00000185012.1
 Gm12728
predicted gene 12728
chr5_+_17574726 6.966 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr5_-_84417359 6.333 ENSMUST00000113401.1
 Epha5
Eph receptor A5
chr4_+_144892813 6.330 ENSMUST00000105744.1
ENSMUST00000171001.1
 Dhrs3

dehydrogenase/reductase (SDR family) member 3

chr11_+_57011945 6.105 ENSMUST00000094179.4
 Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr11_+_57011798 5.991 ENSMUST00000036315.9
 Gria1
glutamate receptor, ionotropic, AMPA1 (alpha 1)
chr4_+_119814495 5.389 ENSMUST00000106307.2
 Hivep3
human immunodeficiency virus type I enhancer binding protein 3
chr4_+_144893077 5.150 ENSMUST00000154208.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chrX_+_159840463 5.066 ENSMUST00000112451.1
ENSMUST00000112453.2
 Sh3kbp1

SH3-domain kinase binding protein 1

chr1_+_45981548 4.863 ENSMUST00000085632.2
 Rpl23a-ps1
ribosomal protein 23A, pseudogene 1
chr18_+_37355271 4.853 ENSMUST00000051163.1
 Pcdhb8
protocadherin beta 8
chr4_+_144893127 4.617 ENSMUST00000142808.1
 Dhrs3
dehydrogenase/reductase (SDR family) member 3
chr12_+_29528382 4.609 ENSMUST00000049784.9
 Myt1l
myelin transcription factor 1-like
chr8_+_47713266 4.225 ENSMUST00000180928.1
 E030037K01Rik
RIKEN cDNA E030037K01 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 83 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 21.5 GO:0001919 regulation of receptor recycling(GO:0001919)
1.6 17.6 GO:0042572 retinol metabolic process(GO:0042572)
0.2 15.5 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.2 14.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
3.7 11.1 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.7 8.0 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
2.5 7.4 GO:0001928 regulation of exocyst assembly(GO:0001928)
1.0 7.0 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.7 6.8 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 6.6 GO:0030901 midbrain development(GO:0030901)
0.2 6.5 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.1 6.4 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 5.7 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.1 5.4 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.2 5.0 GO:0006089 lactate metabolic process(GO:0006089)
0.1 4.9 GO:0006376 mRNA splice site selection(GO:0006376)
0.7 4.4 GO:0072318 clathrin coat disassembly(GO:0072318)
0.0 4.0 GO:0072332 intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332)
1.3 3.8 GO:2001139 negative regulation of postsynaptic membrane organization(GO:1901627) negative regulation of dendritic spine maintenance(GO:1902951) negative regulation of phospholipid efflux(GO:1902999) regulation of lipid transport across blood brain barrier(GO:1903000) negative regulation of lipid transport across blood brain barrier(GO:1903001) positive regulation of lipid transport across blood brain barrier(GO:1903002) negative regulation of phospholipid transport(GO:2001139)
0.5 3.6 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 21.6 GO:0005911 cell-cell junction(GO:0005911)
2.0 12.1 GO:0044308 axonal spine(GO:0044308)
0.0 12.0 GO:0045211 postsynaptic membrane(GO:0045211)
0.6 9.5 GO:0032279 asymmetric synapse(GO:0032279)
0.1 7.8 GO:0042641 actomyosin(GO:0042641)
0.1 6.3 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 6.0 GO:0030425 dendrite(GO:0030425)
0.1 4.8 GO:0048786 presynaptic active zone(GO:0048786)
1.3 3.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 3.5 GO:0060076 excitatory synapse(GO:0060076)
0.1 3.4 GO:0005871 kinesin complex(GO:0005871)
0.2 3.1 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 3.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.3 2.7 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.6 2.5 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 2.4 GO:0035371 microtubule plus-end(GO:0035371)
0.1 2.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.2 2.0 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.1 2.0 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 2.0 GO:0030667 secretory granule membrane(GO:0030667)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 65 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.1 21.6 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
2.3 16.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 7.4 GO:0030275 LRR domain binding(GO:0030275)
0.0 7.3 GO:0005509 calcium ion binding(GO:0005509)
0.6 7.0 GO:0038191 neuropilin binding(GO:0038191)
0.9 6.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.2 6.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 5.4 GO:0005158 insulin receptor binding(GO:0005158)
0.1 4.9 GO:0045296 cadherin binding(GO:0045296)
0.0 4.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 4.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.3 4.0 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 4.0 GO:0002039 p53 binding(GO:0002039)
1.3 3.8 GO:0046911 hydroxyapatite binding(GO:0046848) metal chelating activity(GO:0046911) phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.5 3.6 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.2 3.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 3.3 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.2 3.1 GO:0031402 sodium ion binding(GO:0031402)
0.1 3.1 GO:0043531 ADP binding(GO:0043531)
0.1 3.0 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)