Motif ID: Hoxa5

Z-value: 1.060


Transcription factors associated with Hoxa5:

Gene SymbolEntrez IDGene Name
Hoxa5 ENSMUSG00000038253.6 Hoxa5



Activity profile for motif Hoxa5.

activity profile for motif Hoxa5


Sorted Z-values histogram for motif Hoxa5

Sorted Z-values for motif Hoxa5



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa5

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_25882407 6.243 ENSMUST00000163316.2
 Gm6434
predicted gene 6434
chr11_+_16752203 6.220 ENSMUST00000102884.3
ENSMUST00000020329.6
 Egfr

epidermal growth factor receptor

chr15_-_81843699 5.796 ENSMUST00000092020.2
 Gm8444
predicted gene 8444
chr8_+_57455898 5.733 ENSMUST00000034023.3
 Scrg1
scrapie responsive gene 1
chr17_-_31636631 5.586 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
 Cbs


cystathionine beta-synthase


chrX_+_66653003 5.278 ENSMUST00000036043.4
 Slitrk2
SLIT and NTRK-like family, member 2
chrY_+_1010543 5.212 ENSMUST00000091197.3
 Eif2s3y
eukaryotic translation initiation factor 2, subunit 3, structural gene Y-linked
chr9_+_37367354 5.150 ENSMUST00000051839.7
 Hepacam
hepatocyte cell adhesion molecule
chr10_-_96409038 4.779 ENSMUST00000179683.1
 Gm20091
predicted gene, 20091
chr5_-_62766153 4.516 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_+_17030045 4.396 ENSMUST00000164523.2
 Gm5611
predicted gene 5611
chr18_-_9726670 4.119 ENSMUST00000171339.1
 Gm17430
predicted gene, 17430
chr2_+_14388316 4.093 ENSMUST00000114731.1
ENSMUST00000082290.7
 Slc39a12

solute carrier family 39 (zinc transporter), member 12

chr14_-_25927250 4.075 ENSMUST00000100811.5
 Tmem254a
transmembrane protein 254a
chr7_+_88278085 3.885 ENSMUST00000032779.5
ENSMUST00000128791.1
 Ctsc

cathepsin C

chr1_+_104768510 3.852 ENSMUST00000062528.8
 Cdh20
cadherin 20
chr3_+_62419668 3.722 ENSMUST00000161057.1
 Arhgef26
Rho guanine nucleotide exchange factor (GEF) 26
chr19_-_50030735 3.698 ENSMUST00000071866.1
 Rpl13a-ps1
ribosomal protein 13A, pseudogene 1
chr9_+_94669876 3.393 ENSMUST00000033463.9
 Slc9a9
solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr5_-_62765618 3.307 ENSMUST00000159470.1
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 210 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.1 6.3 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343) cysteine biosynthetic process(GO:0019344)
1.6 6.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.5 5.5 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.8 5.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.1 5.3 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.4 5.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
1.0 4.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 4.0 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.2 3.9 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.1 3.8 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.7 3.6 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 3.6 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.5 3.4 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.4 3.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 3.3 GO:0007050 cell cycle arrest(GO:0007050)
0.1 3.1 GO:0035136 forelimb morphogenesis(GO:0035136)
0.0 3.1 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
1.0 3.0 GO:0043696 dedifferentiation(GO:0043696) cell dedifferentiation(GO:0043697)
0.8 3.0 GO:0042938 dipeptide transport(GO:0042938)
1.0 2.9 GO:0021529 spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 106 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 7.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 6.7 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
2.1 6.2 GO:0031983 vesicle lumen(GO:0031983)
0.0 4.6 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.1 3.4 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 3.2 GO:0005802 trans-Golgi network(GO:0005802)
0.3 3.1 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 3.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 2.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.6 GO:0001669 acrosomal vesicle(GO:0001669)
0.1 2.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 2.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 2.5 GO:0055037 recycling endosome(GO:0055037)
0.2 2.3 GO:0097542 ciliary tip(GO:0097542)
0.0 2.3 GO:0016459 myosin complex(GO:0016459)
0.7 2.2 GO:0005927 muscle tendon junction(GO:0005927)
0.1 2.2 GO:0034451 centriolar satellite(GO:0034451)
0.0 2.1 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 2.1 GO:0042641 actomyosin(GO:0042641)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 135 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 8.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 6.6 GO:0003735 structural constituent of ribosome(GO:0003735)
2.1 6.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
1.9 5.6 GO:0098809 nitrite reductase activity(GO:0098809)
0.2 5.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.5 5.4 GO:0038191 neuropilin binding(GO:0038191)
0.1 5.2 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 5.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.3 4.1 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.2 4.0 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.3 3.9 GO:0016505 peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 3.5 GO:0017137 Rab GTPase binding(GO:0017137)
0.4 3.4 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 3.2 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 3.1 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 3.1 GO:0005504 fatty acid binding(GO:0005504)
1.0 3.0 GO:0043912 D-lysine oxidase activity(GO:0043912)
0.6 3.0 GO:0042895 antibiotic transporter activity(GO:0042895)
0.1 3.0 GO:0030332 cyclin binding(GO:0030332)
0.1 2.9 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)