Motif ID: Hoxa6

Z-value: 0.634


Transcription factors associated with Hoxa6:

Gene SymbolEntrez IDGene Name
Hoxa6 ENSMUSG00000043219.8 Hoxa6



Activity profile for motif Hoxa6.

activity profile for motif Hoxa6


Sorted Z-values histogram for motif Hoxa6

Sorted Z-values for motif Hoxa6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxa6

PNG image of the network

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Top targets:


Showing 1 to 20 of 184 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_55681257 7.356 ENSMUST00000044767.8
Neurod6
neurogenic differentiation 6
chr1_+_19103022 5.621 ENSMUST00000037294.7
Tfap2d
transcription factor AP-2, delta
chr2_+_61804453 3.897 ENSMUST00000048934.8
Tbr1
T-box brain gene 1
chr11_+_77930800 3.849 ENSMUST00000093995.3
ENSMUST00000000646.7
Sez6

seizure related gene 6

chr14_+_75455957 3.834 ENSMUST00000164848.1
Siah3
seven in absentia homolog 3 (Drosophila)
chr3_+_18054258 3.465 ENSMUST00000026120.6
Bhlhe22
basic helix-loop-helix family, member e22
chr4_-_110292719 3.355 ENSMUST00000106601.1
Elavl4
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr2_+_71528657 3.345 ENSMUST00000126400.1
Dlx1
distal-less homeobox 1
chr5_-_123141067 3.012 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
AI480526


expressed sequence AI480526


chr1_+_6730051 2.947 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
St18



suppression of tumorigenicity 18



chr8_-_84773381 2.892 ENSMUST00000109764.1
Nfix
nuclear factor I/X
chr16_+_7069825 2.609 ENSMUST00000056416.7
Rbfox1
RNA binding protein, fox-1 homolog (C. elegans) 1
chr1_+_177445660 2.555 ENSMUST00000077225.6
Zbtb18
zinc finger and BTB domain containing 18
chr4_-_110287479 2.381 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
Elavl4


ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)


chr6_+_15185456 2.364 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
Foxp2



forkhead box P2



chr1_+_187997821 2.246 ENSMUST00000027906.6
Esrrg
estrogen-related receptor gamma
chr1_+_187997835 2.238 ENSMUST00000110938.1
Esrrg
estrogen-related receptor gamma
chr8_-_46294592 1.969 ENSMUST00000058636.7
Helt
helt bHLH transcription factor
chr13_-_28953690 1.945 ENSMUST00000067230.5
Sox4
SRY-box containing gene 4
chr2_-_7395968 1.879 ENSMUST00000002176.6
Celf2
CUGBP, Elav-like family member 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 8.9 GO:0021542 dentate gyrus development(GO:0021542)
0.1 5.7 GO:0043488 regulation of mRNA stability(GO:0043488)
0.4 4.9 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.1 4.3 GO:0021766 hippocampus development(GO:0021766)
0.1 4.0 GO:0006376 mRNA splice site selection(GO:0006376)
0.8 3.9 GO:0001661 conditioned taste aversion(GO:0001661)
0.8 3.8 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.6 3.5 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
1.1 3.4 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.1 3.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
1.1 3.3 GO:0021893 cerebral cortex GABAergic interneuron fate commitment(GO:0021893)
0.4 3.2 GO:0071420 cellular response to histamine(GO:0071420)
0.1 3.0 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.3 2.9 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.3 2.9 GO:0060539 diaphragm development(GO:0060539)
0.6 1.9 GO:0003289 atrial septum primum morphogenesis(GO:0003289) ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.8 1.7 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.3 1.7 GO:0072318 clathrin coat disassembly(GO:0072318)
0.2 1.6 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.3 1.5 GO:0021856 cerebral cortex tangential migration using cell-axon interactions(GO:0021824) gonadotrophin-releasing hormone neuronal migration to the hypothalamus(GO:0021828) hypothalamic tangential migration using cell-axon interactions(GO:0021856) facioacoustic ganglion development(GO:1903375)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.4 5.7 GO:0042788 polysomal ribosome(GO:0042788)
0.1 4.2 GO:0045171 intercellular bridge(GO:0045171)
0.1 4.0 GO:0097440 apical dendrite(GO:0097440)
0.2 3.2 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 2.9 GO:0005802 trans-Golgi network(GO:0005802)
0.0 1.7 GO:0016363 nuclear matrix(GO:0016363)
0.0 1.5 GO:0044295 axonal growth cone(GO:0044295)
0.1 1.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.1 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.2 0.9 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.8 GO:0005677 chromatin silencing complex(GO:0005677)
0.1 0.7 GO:0030478 actin cap(GO:0030478)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.1 0.6 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.6 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.2 0.5 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 0.4 GO:0008623 CHRAC(GO:0008623)
0.0 0.4 GO:0035102 PRC1 complex(GO:0035102)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 38 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.8 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
0.2 5.7 GO:0017091 AU-rich element binding(GO:0017091)
0.2 4.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 3.8 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.2 3.2 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 3.0 GO:0003729 mRNA binding(GO:0003729)
0.0 2.4 GO:0001046 core promoter sequence-specific DNA binding(GO:0001046)
0.0 2.3 GO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding(GO:0000981)
0.0 2.2 GO:0001158 enhancer sequence-specific DNA binding(GO:0001158)
0.1 2.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.3 1.7 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.7 GO:0017124 SH3 domain binding(GO:0017124)
0.1 1.5 GO:0038191 neuropilin binding(GO:0038191)
1.4 1.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.3 1.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.2 1.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.4 1.2 GO:0016015 morphogen activity(GO:0016015)
0.0 1.2 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.2 1.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.1 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)