Motif ID: Hoxb1

Z-value: 0.575


Transcription factors associated with Hoxb1:

Gene SymbolEntrez IDGene Name
Hoxb1 ENSMUSG00000018973.2 Hoxb1



Activity profile for motif Hoxb1.

activity profile for motif Hoxb1


Sorted Z-values histogram for motif Hoxb1

Sorted Z-values for motif Hoxb1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb1

PNG image of the network

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Top targets:


Showing 1 to 20 of 69 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_73391160 4.910 ENSMUST00000128471.1
 Rgma
RGM domain family, member A
chr1_-_119053339 4.500 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
 Gli2


GLI-Kruppel family member GLI2


chr3_+_127633134 2.988 ENSMUST00000029587.7
 Neurog2
neurogenin 2
chr1_-_119053619 2.286 ENSMUST00000062483.8
 Gli2
GLI-Kruppel family member GLI2
chr2_+_124610278 1.954 ENSMUST00000051419.8
ENSMUST00000077847.5
ENSMUST00000078621.5
ENSMUST00000076335.5
 Sema6d



sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D



chr2_+_124610573 1.910 ENSMUST00000103239.3
ENSMUST00000103240.2
 Sema6d

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D

chr19_-_41743665 1.821 ENSMUST00000025993.3
 Slit1
slit homolog 1 (Drosophila)
chrX_+_110814390 1.598 ENSMUST00000078229.3
 Pou3f4
POU domain, class 3, transcription factor 4
chr1_+_127306706 1.489 ENSMUST00000171405.1
 Mgat5
mannoside acetylglucosaminyltransferase 5
chr7_-_97417730 1.384 ENSMUST00000043077.7
 Thrsp
thyroid hormone responsive
chrX_+_166344692 1.370 ENSMUST00000112223.1
ENSMUST00000112224.1
ENSMUST00000112229.2
ENSMUST00000112228.1
ENSMUST00000112227.2
ENSMUST00000112226.2
 Gpm6b





glycoprotein m6b





chr3_-_88762244 1.360 ENSMUST00000183267.1
 Syt11
synaptotagmin XI
chr14_-_69284982 1.326 ENSMUST00000183882.1
ENSMUST00000037064.4
 Slc25a37

solute carrier family 25, member 37

chr14_-_69503220 1.164 ENSMUST00000180059.2
 Gm21464
predicted gene, 21464
chr1_+_178798438 1.109 ENSMUST00000160789.1
 Kif26b
kinesin family member 26B
chr4_+_103114712 0.905 ENSMUST00000143417.1
 Mier1
mesoderm induction early response 1 homolog (Xenopus laevis
chr12_+_38780284 0.903 ENSMUST00000162563.1
ENSMUST00000161164.1
ENSMUST00000160996.1
 Etv1


ets variant gene 1


chr1_-_135688094 0.900 ENSMUST00000112103.1
 Nav1
neuron navigator 1
chr15_+_74516196 0.891 ENSMUST00000042035.9
 Bai1
brain-specific angiogenesis inhibitor 1
chr10_+_127677064 0.889 ENSMUST00000118612.1
ENSMUST00000048099.4
 Tmem194

transmembrane protein 194


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.7 6.8 GO:0060032 notochord regression(GO:0060032)
0.5 4.9 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.1 3.9 GO:0014912 negative regulation of smooth muscle cell migration(GO:0014912)
0.0 3.0 GO:0021954 central nervous system neuron development(GO:0021954)
0.3 1.8 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.2 1.6 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 1.5 GO:0006487 protein N-linked glycosylation(GO:0006487)
0.5 1.4 GO:1905154 negative regulation of tumor necrosis factor secretion(GO:1904468) negative regulation of membrane invagination(GO:1905154)
0.2 1.4 GO:0051611 negative regulation of neurotransmitter uptake(GO:0051581) serotonin uptake(GO:0051610) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 1.4 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.1 1.3 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.4 1.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.4 0.9 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.0 0.9 GO:0007638 mechanosensory behavior(GO:0007638)
0.1 0.8 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.8 GO:0001578 microtubule bundle formation(GO:0001578)
0.1 0.7 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.7 GO:0015804 neutral amino acid transport(GO:0015804)
0.1 0.6 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.6 GO:0007628 adult walking behavior(GO:0007628) walking behavior(GO:0090659)

Gene overrepresentation in cellular_component category:

Showing 1 to 11 of 11 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 6.8 GO:0097542 ciliary tip(GO:0097542)
0.0 4.9 GO:0031225 anchored component of membrane(GO:0031225)
0.2 1.4 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.3 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.1 GO:0005871 kinesin complex(GO:0005871)
0.0 0.6 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.2 GO:0005682 U5 snRNP(GO:0005682)
0.0 0.0 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 21 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.1 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.4 4.9 GO:1990459 transferrin receptor binding(GO:1990459)
0.1 3.9 GO:0030215 semaphorin receptor binding(GO:0030215)
0.1 3.0 GO:0070888 E-box binding(GO:0070888)
0.2 1.8 GO:0048495 Roundabout binding(GO:0048495)
0.1 1.6 GO:0003680 AT DNA binding(GO:0003680)
0.4 1.5 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.3 1.5 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 1.4 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 1.1 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 0.9 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.0 0.7 GO:0008179 adenylate cyclase binding(GO:0008179) receptor signaling complex scaffold activity(GO:0030159)
0.0 0.7 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.5 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 0.4 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)