Motif ID: Hoxb13

Z-value: 0.780


Transcription factors associated with Hoxb13:

Gene SymbolEntrez IDGene Name
Hoxb13 ENSMUSG00000049604.3 Hoxb13



Activity profile for motif Hoxb13.

activity profile for motif Hoxb13


Sorted Z-values histogram for motif Hoxb13

Sorted Z-values for motif Hoxb13



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb13

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr9_-_69451035 4.313 ENSMUST00000071565.5
 Gm4978
predicted gene 4978
chr11_+_120948480 3.501 ENSMUST00000070653.6
 Slc16a3
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr9_+_65890237 3.448 ENSMUST00000045802.6
 2810417H13Rik
RIKEN cDNA 2810417H13 gene
chr4_+_105789869 3.362 ENSMUST00000184254.1
 Gm12728
predicted gene 12728
chr3_-_150073620 3.337 ENSMUST00000057740.5
 Rpsa-ps10
ribosomal protein SA, pseudogene 10
chr13_+_96082158 3.065 ENSMUST00000185178.1
 Gm17190
predicted gene 17190
chr3_+_106034661 2.950 ENSMUST00000170669.2
 Gm4540
predicted gene 4540
chr4_-_92191749 2.917 ENSMUST00000123179.1
 Gm12666
predicted gene 12666
chr12_+_33957645 2.623 ENSMUST00000049089.5
 Twist1
twist basic helix-loop-helix transcription factor 1
chr15_+_25773985 2.575 ENSMUST00000125667.1
 Myo10
myosin X
chr14_-_47411666 2.485 ENSMUST00000111778.3
 Dlgap5
discs, large (Drosophila) homolog-associated protein 5
chr5_-_28467093 2.431 ENSMUST00000002708.3
 Shh
sonic hedgehog
chr17_-_26095487 2.427 ENSMUST00000025007.5
 Nme4
NME/NM23 nucleoside diphosphate kinase 4
chr3_+_54481429 2.413 ENSMUST00000091130.3
 Gm5641
predicted gene 5641
chr10_+_63061582 2.390 ENSMUST00000020266.8
ENSMUST00000178684.1
 Pbld1

phenazine biosynthesis-like protein domain containing 1

chr6_-_42520325 2.384 ENSMUST00000104977.2
 Gm4877
predicted gene 4877
chr1_-_51941261 2.321 ENSMUST00000097103.3
 Gm8420
predicted gene 8420
chrX_-_139714481 2.276 ENSMUST00000183728.1
 Gm15013
predicted gene 15013
chr12_+_79297345 2.177 ENSMUST00000079533.5
ENSMUST00000171210.1
 Rad51b

RAD51 homolog B

chr17_+_87635974 2.169 ENSMUST00000053577.8
 Epcam
epithelial cell adhesion molecule

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 350 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 6.0 GO:0006284 base-excision repair(GO:0006284)
0.8 4.7 GO:2000275 regulation of oxidative phosphorylation uncoupler activity(GO:2000275)
0.3 4.2 GO:0019985 translesion synthesis(GO:0019985)
0.0 4.1 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
0.1 3.8 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.1 3.7 GO:0009060 aerobic respiration(GO:0009060)
0.0 3.6 GO:0016042 lipid catabolic process(GO:0016042)
0.1 3.5 GO:0051489 regulation of filopodium assembly(GO:0051489)
0.2 3.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 2.8 GO:0006412 translation(GO:0006412)
0.9 2.6 GO:0006597 spermine biosynthetic process(GO:0006597)
0.6 2.5 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.5 2.5 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.2 2.5 GO:0010388 cullin deneddylation(GO:0010388)
0.8 2.4 GO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development(GO:0060769) kidney smooth muscle tissue development(GO:0072194) negative regulation of dopaminergic neuron differentiation(GO:1904339)
0.8 2.4 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.3 2.4 GO:0006183 GTP biosynthetic process(GO:0006183)
0.0 2.4 GO:0070303 negative regulation of stress-activated MAPK cascade(GO:0032873) negative regulation of stress-activated protein kinase signaling cascade(GO:0070303)
0.2 2.3 GO:0051451 myoblast migration(GO:0051451)
0.1 2.3 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 149 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 8.7 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 7.7 GO:0016459 myosin complex(GO:0016459)
0.1 5.1 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.7 4.9 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.7 3.7 GO:0008623 CHRAC(GO:0008623)
0.1 3.6 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 3.2 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.1 2.9 GO:0030894 replisome(GO:0030894)
0.0 2.8 GO:0016363 nuclear matrix(GO:0016363)
0.0 2.8 GO:0000776 kinetochore(GO:0000776)
0.2 2.7 GO:0045239 tricarboxylic acid cycle enzyme complex(GO:0045239)
0.4 2.5 GO:0097452 GAIT complex(GO:0097452)
0.2 2.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 2.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 2.3 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.1 2.3 GO:0008180 COP9 signalosome(GO:0008180)
0.0 2.3 GO:0005811 lipid particle(GO:0005811)
0.4 2.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 2.2 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 2.1 GO:0036464 cytoplasmic ribonucleoprotein granule(GO:0036464)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 238 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.7 GO:0051015 actin filament binding(GO:0051015)
0.0 7.3 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 5.0 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.5 4.9 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.0 3.8 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 3.7 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
1.1 3.4 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 3.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.5 3.3 GO:0000150 recombinase activity(GO:0000150)
0.0 3.2 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 3.1 GO:0003746 translation elongation factor activity(GO:0003746)
0.6 2.6 GO:0019808 polyamine binding(GO:0019808)
0.2 2.6 GO:0016805 dipeptidase activity(GO:0016805)
0.0 2.6 GO:0035064 methylated histone binding(GO:0035064)
0.8 2.5 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.1 2.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 2.5 GO:0030145 manganese ion binding(GO:0030145)
0.5 2.4 GO:0005113 patched binding(GO:0005113)
0.2 2.4 GO:0036310 annealing helicase activity(GO:0036310)
0.1 2.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)