• All motifs sorted by activity significance
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• Mean activities
• All promoters sorted by FOV

• Activities table
• Activity deltas table
• Regulatory interactions
• Motifs sorted by significance (text)
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Motif ID: Hoxb3

Z-value: 1.232

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Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chrX_+_170009892	29.581	ENSMUST00000180251.1	Gm21887	predicted gene, 21887
chr15_-_8710734	16.253	ENSMUST00000005493.7	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8710409	15.675	ENSMUST00000157065.1	Slc1a3	solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrY_+_90785442	15.193	ENSMUST00000177591.1 ENSMUST00000177671.1 ENSMUST00000179077.1	Erdr1	erythroid differentiation regulator 1
chr2_-_156392829	14.275	ENSMUST00000088578.2	2900097C17Rik	RIKEN cDNA 2900097C17 gene
chr12_+_74288735	10.520	ENSMUST00000095617.1	1700086L19Rik	RIKEN cDNA 1700086L19 gene
chrX_+_170010744	9.313	ENSMUST00000178789.1	Gm21887	predicted gene, 21887
chrY_+_90784738	8.877	ENSMUST00000179483.1	Erdr1	erythroid differentiation regulator 1
chr12_+_84069325	8.688	ENSMUST00000046422.4 ENSMUST00000072505.4	Acot5	acyl-CoA thioesterase 5
chr12_-_24493656	8.455	ENSMUST00000073088.2	Gm16372	predicted pseudogene 16372
chr9_-_54661666	7.926	ENSMUST00000128624.1	Acsbg1	acyl-CoA synthetase bubblegum family member 1
chr5_-_84417359	7.823	ENSMUST00000113401.1	Epha5	Eph receptor A5
chr19_+_3323301	7.794	ENSMUST00000025835.4	Cpt1a	carnitine palmitoyltransferase 1a, liver
chr9_-_54661870	7.594	ENSMUST00000034822.5	Acsbg1	acyl-CoA synthetase bubblegum family member 1
chr4_-_14621805	7.248	ENSMUST00000042221.7	Slc26a7	solute carrier family 26, member 7
chr16_-_52296924	6.687	ENSMUST00000167115.1	Alcam	activated leukocyte cell adhesion molecule
chr7_-_140154712	6.499	ENSMUST00000059241.7	Sprn	shadow of prion protein
chr12_+_16653470	6.488	ENSMUST00000111064.1	Ntsr2	neurotensin receptor 2
chr5_+_63812447	6.462	ENSMUST00000081747.3	0610040J01Rik	RIKEN cDNA 0610040J01 gene
chr11_+_101665541	6.035	ENSMUST00000039388.2	Arl4d	ADP-ribosylation factor-like 4D
chr10_-_83648631	5.903	ENSMUST00000146876.2 ENSMUST00000176294.1	Appl2	adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2
chr5_+_134932351	5.773	ENSMUST00000047196.7 ENSMUST00000111221.2 ENSMUST00000111219.1 ENSMUST00000068617.5 ENSMUST00000111218.1 ENSMUST00000136246.1	Wbscr27	Williams Beuren syndrome chromosome region 27 (human)
chr8_+_54954728	5.393	ENSMUST00000033915.7	Gpm6a	glycoprotein m6a
chr8_+_66386292	5.355	ENSMUST00000039540.5 ENSMUST00000110253.2	March1	membrane-associated ring finger (C3HC4) 1
chr4_+_102570065	5.311	ENSMUST00000097950.2	Pde4b	phosphodiesterase 4B, cAMP specific
chr3_-_121263314	5.125	ENSMUST00000029777.7	Tmem56	transmembrane protein 56
chr10_+_40349265	4.873	ENSMUST00000044672.4 ENSMUST00000095743.2	Cdk19	cyclin-dependent kinase 19
chr2_+_116067213	4.840	ENSMUST00000152412.1	G630016G05Rik	RIKEN cDNA G630016G05 gene
chr5_-_77115145	4.829	ENSMUST00000081964.5	Hopx	HOP homeobox
chr8_+_40354303	4.790	ENSMUST00000136835.1	Micu3	mitochondrial calcium uptake family, member 3
chr12_-_25096080	4.520	ENSMUST00000020974.6	Id2	inhibitor of DNA binding 2
chr9_-_55919605	4.464	ENSMUST00000037408.8	Scaper	S phase cyclin A-associated protein in the ER
chr12_-_83487708	4.312	ENSMUST00000177959.1 ENSMUST00000178756.1	Dpf3	D4, zinc and double PHD fingers, family 3
chr9_-_15301555	4.302	ENSMUST00000034414.8	4931406C07Rik	RIKEN cDNA 4931406C07 gene
chr3_-_85722474	4.197	ENSMUST00000119077.1	Fam160a1	family with sequence similarity 160, member A1
chr9_+_94669876	3.983	ENSMUST00000033463.9	Slc9a9	solute carrier family 9 (sodium/hydrogen exchanger), member 9
chr18_+_37355271	3.901	ENSMUST00000051163.1	Pcdhb8	protocadherin beta 8
chr13_-_92483996	3.857	ENSMUST00000040106.7	Fam151b	family with sequence similarity 151, member B
chr9_-_96719404	3.841	ENSMUST00000140121.1	Zbtb38	zinc finger and BTB domain containing 38
chr13_+_94083490	3.727	ENSMUST00000156071.1	Lhfpl2	lipoma HMGIC fusion partner-like 2
chr19_-_32061438	3.692	ENSMUST00000096119.4	Asah2	N-acylsphingosine amidohydrolase 2
chr14_-_64455903	3.628	ENSMUST00000067927.7	Msra	methionine sulfoxide reductase A
chrX_+_100729917	3.623	ENSMUST00000019503.7	Gdpd2	glycerophosphodiester phosphodiesterase domain containing 2
chr9_-_96719549	3.349	ENSMUST00000128269.1	Zbtb38	zinc finger and BTB domain containing 38
chr1_+_165461037	3.156	ENSMUST00000027853.5	Mpc2	mitochondrial pyruvate carrier 2
chr2_-_45112890	2.913	ENSMUST00000076836.6	Zeb2	zinc finger E-box binding homeobox 2
chr7_+_67222544	2.853	ENSMUST00000058771.5 ENSMUST00000179106.1	Lysmd4	LysM, putative peptidoglycan-binding, domain containing 4
chr2_+_65620829	2.845	ENSMUST00000028377.7	Scn2a1	sodium channel, voltage-gated, type II, alpha 1
chr18_+_12741324	2.836	ENSMUST00000115857.2 ENSMUST00000121018.1 ENSMUST00000119108.1	Cabyr	calcium-binding tyrosine-(Y)-phosphorylation regulated (fibrousheathin 2)
chr2_+_3424123	2.719	ENSMUST00000061852.5 ENSMUST00000100463.3 ENSMUST00000102988.3 ENSMUST00000115066.1	Dclre1c	DNA cross-link repair 1C, PSO2 homolog (S. cerevisiae)
chr4_-_14621494	2.682	ENSMUST00000149633.1	Slc26a7	solute carrier family 26, member 7
chr2_+_119047129	2.650	ENSMUST00000153300.1 ENSMUST00000028799.5	Casc5	cancer susceptibility candidate 5
chr4_-_155645408	2.609	ENSMUST00000115821.2	Gm10563	predicted gene 10563
chr10_-_8886033	2.555	ENSMUST00000015449.5	Sash1	SAM and SH3 domain containing 1
chr9_-_120068263	2.445	ENSMUST00000064165.3 ENSMUST00000177637.1	Cx3cr1	chemokine (C-X3-C) receptor 1
chr2_-_116067391	2.406	ENSMUST00000140185.1	2700033N17Rik	RIKEN cDNA 2700033N17 gene
chr5_-_106926245	2.283	ENSMUST00000117588.1	Hfm1	HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr2_-_20943413	2.133	ENSMUST00000140230.1	Arhgap21	Rho GTPase activating protein 21
chr3_+_65666223	2.105	ENSMUST00000099075.2 ENSMUST00000107848.1 ENSMUST00000161794.1	Lekr1	leucine, glutamate and lysine rich 1
chr9_-_105395237	2.064	ENSMUST00000140851.1	Nek11	NIMA (never in mitosis gene a)-related expressed kinase 11
chr1_-_33814516	2.000	ENSMUST00000044455.5 ENSMUST00000115167.1	Zfp451	zinc finger protein 451
chr19_+_60811574	1.948	ENSMUST00000128357.1 ENSMUST00000119633.1 ENSMUST00000025957.8	Fam45a	family with sequence similarity 45, member A
chr9_-_75597643	1.939	ENSMUST00000164100.1	Tmod2	tropomodulin 2
chr8_+_113635550	1.864	ENSMUST00000179926.1	Mon1b	MON1 homolog b (yeast)
chr9_+_119341487	1.856	ENSMUST00000175743.1 ENSMUST00000176397.1	Acaa1a	acetyl-Coenzyme A acyltransferase 1A
chr2_+_119047116	1.834	ENSMUST00000152380.1 ENSMUST00000099542.2	Casc5	cancer susceptibility candidate 5
chrX_-_9256899	1.814	ENSMUST00000115553.2	Gm14862	predicted gene 14862
chr5_-_74531619	1.792	ENSMUST00000113542.2 ENSMUST00000072857.6 ENSMUST00000121330.1 ENSMUST00000151474.1	Scfd2	Sec1 family domain containing 2
chr18_+_38296635	1.768	ENSMUST00000072376.5 ENSMUST00000170811.1	Rnf14	ring finger protein 14
chr7_-_67222412	1.743	ENSMUST00000181631.1	1700112J16Rik	RIKEN cDNA 1700112J16 gene
chr11_+_116843278	1.722	ENSMUST00000106370.3	Mettl23	methyltransferase like 23
chr8_+_113635787	1.707	ENSMUST00000035777.8	Mon1b	MON1 homolog b (yeast)
chr18_+_49832622	1.661	ENSMUST00000180611.1	Dmxl1	Dmx-like 1
chr14_-_46822232	1.658	ENSMUST00000111817.1 ENSMUST00000079314.5	Gmfb	glia maturation factor, beta
chr5_-_118244861	1.558	ENSMUST00000117177.1 ENSMUST00000133372.1 ENSMUST00000154786.1 ENSMUST00000121369.1	Rnft2	ring finger protein, transmembrane 2
chr12_+_84285232	1.541	ENSMUST00000123614.1 ENSMUST00000147363.1 ENSMUST00000135001.1 ENSMUST00000146377.1	Ptgr2	prostaglandin reductase 2
chr14_+_99298652	1.484	ENSMUST00000005279.6	Klf5	Kruppel-like factor 5
chr11_+_103116228	1.428	ENSMUST00000053063.5	Hexim1	hexamethylene bis-acetamide inducible 1
chr2_+_91257323	1.427	ENSMUST00000111349.2 ENSMUST00000131711.1	Pacsin3	protein kinase C and casein kinase substrate in neurons 3
chr12_-_98577940	1.388	ENSMUST00000110113.1	Kcnk10	potassium channel, subfamily K, member 10
chr9_-_119341390	1.340	ENSMUST00000139870.1	Myd88	myeloid differentiation primary response gene 88
chr5_+_136987019	1.317	ENSMUST00000004968.4	Plod3	procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr2_-_161109017	1.304	ENSMUST00000039782.7 ENSMUST00000134178.1	Chd6	chromodomain helicase DNA binding protein 6
chrM_+_10167	1.255	ENSMUST00000082414.1	mt-Nd4	mitochondrially encoded NADH dehydrogenase 4
chr13_-_67332525	1.221	ENSMUST00000168892.1 ENSMUST00000109735.2	Zfp595	zinc finger protein 595
chr7_+_57387304	1.192	ENSMUST00000085241.5	Gm9962	predicted gene 9962
chr3_-_62506970	1.177	ENSMUST00000029336.4	Dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr14_-_75754475	1.124	ENSMUST00000049168.7	Cog3	component of oligomeric golgi complex 3
chr2_-_150255591	1.108	ENSMUST00000063463.5	Gm21994	predicted gene 21994
chr10_+_116018213	1.072	ENSMUST00000063470.4	Ptprr	protein tyrosine phosphatase, receptor type, R
chr4_-_41045381	1.036	ENSMUST00000054945.7	Aqp7	aquaporin 7
chr10_+_90071095	1.015	ENSMUST00000183109.1	Anks1b	ankyrin repeat and sterile alpha motif domain containing 1B
chr3_-_106014630	1.009	ENSMUST00000010280.4	Pifo	primary cilia formation
chr12_-_98901478	0.994	ENSMUST00000065716.6	Eml5	echinoderm microtubule associated protein like 5
chr9_+_119341294	0.993	ENSMUST00000039784.5	Acaa1a	acetyl-Coenzyme A acyltransferase 1A
chr11_-_121388186	0.975	ENSMUST00000106107.2	Rab40b	Rab40b, member RAS oncogene family
chr19_-_32196393	0.960	ENSMUST00000151822.1	Sgms1	sphingomyelin synthase 1
chr14_+_26259109	0.951	ENSMUST00000174494.1	Duxbl3	double homeobox B-like 3
chr1_-_52233211	0.938	ENSMUST00000114513.2 ENSMUST00000114510.1	Gls	glutaminase
chr9_-_85749308	0.913	ENSMUST00000039213.8	Ibtk	inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr7_-_13053684	0.880	ENSMUST00000182490.1	Mzf1	myeloid zinc finger 1
chr10_+_116143881	0.866	ENSMUST00000105271.2	Ptprr	protein tyrosine phosphatase, receptor type, R
chr17_-_45659312	0.777	ENSMUST00000120717.1	Capn11	calpain 11
chr7_-_44929410	0.710	ENSMUST00000107857.3 ENSMUST00000085399.6 ENSMUST00000167930.1 ENSMUST00000166972.1	Ap2a1	adaptor-related protein complex 2, alpha 1 subunit
chr16_-_10543028	0.661	ENSMUST00000184863.1 ENSMUST00000038281.5	Dexi	dexamethasone-induced transcript
chr6_+_65042575	0.614	ENSMUST00000031984.6	Smarcad1	SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin, subfamily a, containing DEAD/H box 1
chr14_+_25980039	0.596	ENSMUST00000173155.1	Duxbl1	double homeobox B-like 1
chr5_+_140607334	0.576	ENSMUST00000031555.1	Lfng	LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr13_+_4191163	0.562	ENSMUST00000021634.2	Akr1c13	aldo-keto reductase family 1, member C13
chr10_-_128589650	0.557	ENSMUST00000082059.6	Erbb3	v-erb-b2 erythroblastic leukemia viral oncogene homolog 3 (avian)
chr7_-_45092130	0.449	ENSMUST00000148175.1	Rcn3	reticulocalbin 3, EF-hand calcium binding domain
chr14_+_26119811	0.442	ENSMUST00000173617.1	Duxbl2	doubl homeobox B-like 2
chr7_-_45091713	0.373	ENSMUST00000141576.1	Rcn3	reticulocalbin 3, EF-hand calcium binding domain
chrX_+_9885622	0.372	ENSMUST00000067529.2 ENSMUST00000086165.3	Sytl5	synaptotagmin-like 5
chr2_-_132247747	0.330	ENSMUST00000110163.1 ENSMUST00000180286.1 ENSMUST00000028816.2	Tmem230	transmembrane protein 230
chr10_-_117148474	0.322	ENSMUST00000020381.3	Frs2	fibroblast growth factor receptor substrate 2
chr4_-_14621669	0.303	ENSMUST00000143105.1	Slc26a7	solute carrier family 26, member 7
chr2_+_32288317	0.286	ENSMUST00000131712.1 ENSMUST00000133113.1 ENSMUST00000081670.6 ENSMUST00000147707.1 ENSMUST00000129193.1	Golga2	golgi autoantigen, golgin subfamily a, 2
chr7_-_5413145	0.253	ENSMUST00000108569.2	Vmn1r58	vomeronasal 1 receptor 58
chr1_+_115684727	0.250	ENSMUST00000043725.7	Cntnap5a	contactin associated protein-like 5A
chr1_-_184999549	0.249	ENSMUST00000027929.4	Mark1	MAP/microtubule affinity-regulating kinase 1
chr10_-_125328957	0.209	ENSMUST00000063318.2	Slc16a7	solute carrier family 16 (monocarboxylic acid transporters), member 7
chr13_-_21716143	0.181	ENSMUST00000091756.1	Hist1h2bl	histone cluster 1, H2bl
chr13_-_56895737	0.129	ENSMUST00000022023.6 ENSMUST00000109871.1	Trpc7	transient receptor potential cation channel, subfamily C, member 7
chr5_-_137531204	0.124	ENSMUST00000150063.2	Gnb2	guanine nucleotide binding protein (G protein), beta 2
chrM_+_9870	0.117	ENSMUST00000084013.1	mt-Nd4l	mitochondrially encoded NADH dehydrogenase 4L
chr19_-_11604828	0.076	ENSMUST00000025582.4	Ms4a6d	membrane-spanning 4-domains, subfamily A, member 6D
chr18_+_9958147	0.054	ENSMUST00000025137.7	Thoc1	THO complex 1
chr14_+_62292475	0.008	ENSMUST00000166879.1	Rnaseh2b	ribonuclease H2, subunit B

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
8.0	31.9	GO:0043490	malate-aspartate shuttle(GO:0043490)
2.2	8.7	GO:0032788	saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
1.5	10.2	GO:0019532	oxalate transport(GO:0019532)
1.2	3.6	GO:0019085	early viral transcription(GO:0019085)
0.9	4.5	GO:0061030	epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.9	2.6	GO:1902498	regulation of protein autoubiquitination(GO:1902498)
0.8	3.4	GO:1901475	pyruvate transmembrane transport(GO:1901475)
0.8	7.8	GO:0071372	cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.8	4.7	GO:0043415	positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.7	2.8	GO:0008627	intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.6	7.8	GO:0032000	positive regulation of fatty acid beta-oxidation(GO:0032000)
0.6	2.4	GO:1900272	negative regulation of long-term synaptic potentiation(GO:1900272)
0.6	1.8	GO:2000616	negative regulation of histone H3-K9 acetylation(GO:2000616)
0.6	4.0	GO:1990118	sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.6	18.4	GO:0000038	very long-chain fatty acid metabolic process(GO:0000038)
0.5	2.9	GO:1903056	mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.5	1.9	GO:0038128	ERBB2 signaling pathway(GO:0038128)
0.4	1.3	GO:2000338	positive regulation of interleukin-23 production(GO:0032747) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.4	1.3	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.4	2.1	GO:0051684	maintenance of Golgi location(GO:0051684)
0.4	5.3	GO:1901898	negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.4	3.6	GO:0090527	actin filament reorganization(GO:0090527)
0.3	2.7	GO:0031848	protection from non-homologous end joining at telomere(GO:0031848)
0.3	1.9	GO:0051694	pointed-end actin filament capping(GO:0051694)
0.3	4.5	GO:0034501	protein localization to kinetochore(GO:0034501)
0.3	19.5	GO:0035019	somatic stem cell population maintenance(GO:0035019)
0.3	5.4	GO:0002495	antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.3	1.7	GO:0034316	negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.3	1.0	GO:0015793	glycerol transport(GO:0015793)
0.3	2.3	GO:0000712	resolution of meiotic recombination intermediates(GO:0000712)
0.2	1.5	GO:0060576	intestinal epithelial cell development(GO:0060576)
0.2	0.7	GO:1900126	negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.2	0.6	GO:0007386	compartment pattern specification(GO:0007386)
0.2	0.9	GO:0006543	glutamine catabolic process(GO:0006543)
0.1	6.7	GO:0007157	heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1	5.4	GO:0051491	positive regulation of filopodium assembly(GO:0051491)
0.1	1.4	GO:0030322	stabilization of membrane potential(GO:0030322)
0.1	2.1	GO:0031573	intra-S DNA damage checkpoint(GO:0031573)
0.1	1.0	GO:0006686	sphingomyelin biosynthetic process(GO:0006686)
0.1	6.5	GO:0007200	phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.1	1.0	GO:1900383	regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.1	1.3	GO:0006120	mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1	1.3	GO:0070831	basement membrane assembly(GO:0070831)
0.1	0.3	GO:0060527	prostate glandular acinus morphogenesis(GO:0060526) prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis(GO:0060527)
0.1	1.4	GO:0051044	positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.1	4.9	GO:0050729	positive regulation of inflammatory response(GO:0050729)
0.1	0.6	GO:0070886	positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1	1.4	GO:1901798	positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.1	1.8	GO:0060765	regulation of androgen receptor signaling pathway(GO:0060765)
0.1	0.3	GO:0060050	positive regulation of protein glycosylation(GO:0060050)
0.1	0.6	GO:0070933	histone H4 deacetylation(GO:0070933)
0.1	1.1	GO:0000301	retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0	1.8	GO:0006904	vesicle docking involved in exocytosis(GO:0006904)
0.0	4.3	GO:0098792	xenophagy(GO:0098792)
0.0	1.2	GO:0043330	response to exogenous dsRNA(GO:0043330)
0.0	3.7	GO:0006665	sphingolipid metabolic process(GO:0006665)
0.0	0.6	GO:0006693	prostanoid metabolic process(GO:0006692) prostaglandin metabolic process(GO:0006693)
0.0	1.0	GO:0031344	regulation of cell projection organization(GO:0031344)
0.0	0.1	GO:0048296	isotype switching to IgA isotypes(GO:0048290) regulation of isotype switching to IgA isotypes(GO:0048296)
0.0	2.8	GO:0019722	calcium-mediated signaling(GO:0019722)
0.0	0.9	GO:0051209	release of sequestered calcium ion into cytosol(GO:0051209) negative regulation of sequestering of calcium ion(GO:0051283)
0.0	0.2	GO:0002227	innate immune response in mucosa(GO:0002227)
0.0	0.6	GO:0006805	xenobiotic metabolic process(GO:0006805)
0.0	5.0	GO:0032259	methylation(GO:0032259)
0.0	0.4	GO:0048791	calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0	1.3	GO:0007568	aging(GO:0007568)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
1.9	31.9	GO:0043205	fibril(GO:0043205)
0.4	6.7	GO:0042101	T cell receptor complex(GO:0042101)
0.3	7.5	GO:0031307	integral component of mitochondrial outer membrane(GO:0031307)
0.2	5.3	GO:0000930	gamma-tubulin complex(GO:0000930)
0.2	5.9	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.2	2.8	GO:0035686	sperm fibrous sheath(GO:0035686)
0.2	2.7	GO:0070419	nonhomologous end joining complex(GO:0070419)
0.2	2.8	GO:0034706	voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1	27.1	GO:0005777	peroxisome(GO:0005777) microbody(GO:0042579)
0.1	5.4	GO:0031902	late endosome membrane(GO:0031902)
0.1	7.8	GO:0005791	rough endoplasmic reticulum(GO:0005791)
0.1	5.4	GO:0044295	axonal growth cone(GO:0044295)
0.1	1.0	GO:0000138	Golgi trans cisterna(GO:0000138)
0.1	1.9	GO:0005865	striated muscle thin filament(GO:0005865)
0.1	1.1	GO:0017119	Golgi transport complex(GO:0017119)
0.1	1.3	GO:0005665	DNA-directed RNA polymerase II, core complex(GO:0005665)
0.1	5.3	GO:0001669	acrosomal vesicle(GO:0001669)
0.1	2.4	GO:0032809	neuronal cell body membrane(GO:0032809)
0.1	1.6	GO:0071565	nBAF complex(GO:0071565)
0.1	6.5	GO:0031225	anchored component of membrane(GO:0031225)
0.0	0.7	GO:0032433	filopodium tip(GO:0032433)
0.0	4.1	GO:0072562	blood microparticle(GO:0072562)
0.0	0.3	GO:0000137	Golgi cis cisterna(GO:0000137)
0.0	3.5	GO:0043198	dendritic shaft(GO:0043198)
0.0	8.4	GO:0016323	basolateral plasma membrane(GO:0016323)
0.0	4.0	GO:0055037	recycling endosome(GO:0055037)
0.0	0.6	GO:0035861	site of double-strand break(GO:0035861)
0.0	1.4	GO:0070469	respiratory chain(GO:0070469)
0.0	1.4	GO:0005802	trans-Golgi network(GO:0005802)
0.0	1.9	GO:0005884	actin filament(GO:0005884)
0.0	1.3	GO:0014069	postsynaptic density(GO:0014069) postsynaptic specialization(GO:0099572)
0.0	0.6	GO:0030173	integral component of Golgi membrane(GO:0030173)
0.0	0.4	GO:0031526	brush border membrane(GO:0031526)
0.0	3.6	GO:0015629	actin cytoskeleton(GO:0015629)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
6.4	31.9	GO:0005314	high-affinity glutamate transmembrane transporter activity(GO:0005314)
1.6	7.8	GO:0004095	carnitine O-palmitoyltransferase activity(GO:0004095)
1.4	15.5	GO:0031957	very long-chain fatty acid-CoA ligase activity(GO:0031957)
1.0	7.8	GO:0005004	GPI-linked ephrin receptor activity(GO:0005004)
0.9	10.2	GO:0019531	oxalate transmembrane transporter activity(GO:0019531)
0.8	3.4	GO:0050833	pyruvate transmembrane transporter activity(GO:0050833)
0.7	2.8	GO:0008410	CoA-transferase activity(GO:0008410)
0.6	3.7	GO:0017040	ceramidase activity(GO:0017040)
0.5	8.7	GO:0016290	palmitoyl-CoA hydrolase activity(GO:0016290)
0.5	4.0	GO:0005451	monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.5	2.4	GO:0019960	C-X3-C chemokine binding(GO:0019960)
0.4	3.6	GO:0008889	glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.3	6.5	GO:0008188	neuropeptide receptor activity(GO:0008188)
0.3	1.3	GO:0070976	TIR domain binding(GO:0070976)
0.3	1.3	GO:0008475	procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.3	2.7	GO:0035312	5'-3' exodeoxyribonuclease activity(GO:0035312)
0.3	7.2	GO:0008327	methyl-CpG binding(GO:0008327)
0.3	1.8	GO:0061665	SUMO ligase activity(GO:0061665)
0.2	1.0	GO:0033188	sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.2	1.2	GO:0051880	G-quadruplex DNA binding(GO:0051880)
0.2	0.9	GO:0030292	protein tyrosine kinase inhibitor activity(GO:0030292)
0.2	2.8	GO:0043522	leucine zipper domain binding(GO:0043522)
0.2	1.9	GO:0005523	tropomyosin binding(GO:0005523)
0.2	1.4	GO:0097322	7SK snRNA binding(GO:0097322)
0.2	0.6	GO:0033829	O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.2	0.9	GO:0004359	glutaminase activity(GO:0004359)
0.2	0.6	GO:0038132	neuregulin binding(GO:0038132)
0.2	1.0	GO:0015265	urea channel activity(GO:0015265)
0.2	1.7	GO:0071933	Arp2/3 complex binding(GO:0071933)
0.2	6.3	GO:0043015	gamma-tubulin binding(GO:0043015)
0.1	2.8	GO:0042287	MHC protein binding(GO:0042287)
0.1	1.4	GO:0022841	potassium ion leak channel activity(GO:0022841)
0.1	4.9	GO:0097472	cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1	1.4	GO:0019855	calcium channel inhibitor activity(GO:0019855)
0.1	4.3	GO:0044824	integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.1	2.9	GO:0070412	R-SMAD binding(GO:0070412)
0.1	2.1	GO:0031435	mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.1	5.5	GO:0005262	calcium channel activity(GO:0005262)
0.1	0.3	GO:0061676	importin-alpha family protein binding(GO:0061676)
0.0	1.8	GO:0031624	ubiquitin conjugating enzyme binding(GO:0031624) androgen receptor binding(GO:0050681)
0.0	1.4	GO:0050136	NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0	0.8	GO:0004198	calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0	6.3	GO:0017137	Rab GTPase binding(GO:0017137)
0.0	0.3	GO:0005068	transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068) neurotrophin TRKA receptor binding(GO:0005168)
0.0	0.6	GO:0035380	C-3 sterol dehydrogenase (C-4 sterol decarboxylase) activity(GO:0000252) mevaldate reductase activity(GO:0004495) gluconate dehydrogenase activity(GO:0008875) epoxide dehydrogenase activity(GO:0018451) 5-exo-hydroxycamphor dehydrogenase activity(GO:0018452) 2-hydroxytetrahydrofuran dehydrogenase activity(GO:0018453) acetoin dehydrogenase activity(GO:0019152) phenylcoumaran benzylic ether reductase activity(GO:0032442) D-xylose:NADP reductase activity(GO:0032866) L-arabinose:NADP reductase activity(GO:0032867) D-arabinitol dehydrogenase, D-ribulose forming (NADP+) activity(GO:0033709) (R)-(-)-1,2,3,4-tetrahydronaphthol dehydrogenase activity(GO:0034831) 3-hydroxymenthone dehydrogenase activity(GO:0034840) very long-chain-3-hydroxyacyl-CoA dehydrogenase activity(GO:0035380) dihydrotestosterone 17-beta-dehydrogenase activity(GO:0035410) (R)-2-hydroxyisocaproate dehydrogenase activity(GO:0043713) L-arabinose 1-dehydrogenase (NADP+) activity(GO:0044103) L-xylulose reductase (NAD+) activity(GO:0044105) 3-ketoglucose-reductase activity(GO:0048258) D-arabinitol dehydrogenase, D-xylulose forming (NADP+) activity(GO:0052677)
0.0	5.0	GO:0008757	S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.0	3.9	GO:0044325	ion channel binding(GO:0044325)
0.0	0.2	GO:0050321	tau-protein kinase activity(GO:0050321) phosphatidic acid binding(GO:0070300)
0.0	1.5	GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor(GO:0016616)
0.0	1.8	GO:0008565	protein transporter activity(GO:0008565)
0.0	0.3	GO:0004190	aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0	4.6	GO:0005525	GTP binding(GO:0005525)
0.0	0.4	GO:0046875	ephrin receptor binding(GO:0046875)

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