Motif ID: Hoxb3

Z-value: 1.232


Transcription factors associated with Hoxb3:

Gene SymbolEntrez IDGene Name
Hoxb3 ENSMUSG00000048763.5 Hoxb3



Activity profile for motif Hoxb3.

activity profile for motif Hoxb3


Sorted Z-values histogram for motif Hoxb3

Sorted Z-values for motif Hoxb3



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb3

PNG image of the network

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Top targets:


Showing 1 to 20 of 129 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_+_170009892 29.581 ENSMUST00000180251.1
 Gm21887
predicted gene, 21887
chr15_-_8710734 16.253 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr15_-_8710409 15.675 ENSMUST00000157065.1
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrY_+_90785442 15.193 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
 Erdr1


erythroid differentiation regulator 1


chr2_-_156392829 14.275 ENSMUST00000088578.2
 2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr12_+_74288735 10.520 ENSMUST00000095617.1
 1700086L19Rik
RIKEN cDNA 1700086L19 gene
chrX_+_170010744 9.313 ENSMUST00000178789.1
 Gm21887
predicted gene, 21887
chrY_+_90784738 8.877 ENSMUST00000179483.1
 Erdr1
erythroid differentiation regulator 1
chr12_+_84069325 8.688 ENSMUST00000046422.4
ENSMUST00000072505.4
 Acot5

acyl-CoA thioesterase 5

chr12_-_24493656 8.455 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr9_-_54661666 7.926 ENSMUST00000128624.1
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr5_-_84417359 7.823 ENSMUST00000113401.1
 Epha5
Eph receptor A5
chr19_+_3323301 7.794 ENSMUST00000025835.4
 Cpt1a
carnitine palmitoyltransferase 1a, liver
chr9_-_54661870 7.594 ENSMUST00000034822.5
 Acsbg1
acyl-CoA synthetase bubblegum family member 1
chr4_-_14621805 7.248 ENSMUST00000042221.7
 Slc26a7
solute carrier family 26, member 7
chr16_-_52296924 6.687 ENSMUST00000167115.1
 Alcam
activated leukocyte cell adhesion molecule
chr7_-_140154712 6.499 ENSMUST00000059241.7
 Sprn
shadow of prion protein
chr12_+_16653470 6.488 ENSMUST00000111064.1
 Ntsr2
neurotensin receptor 2
chr5_+_63812447 6.462 ENSMUST00000081747.3
 0610040J01Rik
RIKEN cDNA 0610040J01 gene
chr11_+_101665541 6.035 ENSMUST00000039388.2
 Arl4d
ADP-ribosylation factor-like 4D

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 66 entries
Log-likelihood per target Total log-likelihoodTermDescription
8.0 31.9 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.3 19.5 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.6 18.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
1.5 10.2 GO:0019532 oxalate transport(GO:0019532)
2.2 8.7 GO:0032788 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.8 7.8 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.6 7.8 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 6.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 6.5 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.3 5.4 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.1 5.4 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.4 5.3 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 5.0 GO:0032259 methylation(GO:0032259)
0.1 4.9 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.8 4.7 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.9 4.5 GO:0061030 epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.3 4.5 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 4.3 GO:0098792 xenophagy(GO:0098792)
0.6 4.0 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 3.7 GO:0006665 sphingolipid metabolic process(GO:0006665)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 34 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 31.9 GO:0043205 fibril(GO:0043205)
0.1 27.1 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 8.4 GO:0016323 basolateral plasma membrane(GO:0016323)
0.1 7.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.3 7.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.4 6.7 GO:0042101 T cell receptor complex(GO:0042101)
0.1 6.5 GO:0031225 anchored component of membrane(GO:0031225)
0.2 5.9 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.1 5.4 GO:0031902 late endosome membrane(GO:0031902)
0.1 5.4 GO:0044295 axonal growth cone(GO:0044295)
0.2 5.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 5.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 4.1 GO:0072562 blood microparticle(GO:0072562)
0.0 4.0 GO:0055037 recycling endosome(GO:0055037)
0.0 3.6 GO:0015629 actin cytoskeleton(GO:0015629)
0.0 3.5 GO:0043198 dendritic shaft(GO:0043198)
0.2 2.8 GO:0035686 sperm fibrous sheath(GO:0035686)
0.2 2.8 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.2 2.7 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.1 2.4 GO:0032809 neuronal cell body membrane(GO:0032809)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 53 entries
Log-likelihood per target Total log-likelihoodTermDescription
6.4 31.9 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
1.4 15.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.9 10.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.5 8.7 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
1.6 7.8 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
1.0 7.8 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.3 7.2 GO:0008327 methyl-CpG binding(GO:0008327)
0.3 6.5 GO:0008188 neuropeptide receptor activity(GO:0008188)
0.2 6.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 6.3 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 5.5 GO:0005262 calcium channel activity(GO:0005262)
0.0 5.0 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.1 4.9 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.0 4.6 GO:0005525 GTP binding(GO:0005525)
0.1 4.3 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.5 4.0 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.0 3.9 GO:0044325 ion channel binding(GO:0044325)
0.6 3.7 GO:0017040 ceramidase activity(GO:0017040)
0.4 3.6 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.8 3.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)