Motif ID: Hoxb5

Z-value: 1.025


Transcription factors associated with Hoxb5:

Gene SymbolEntrez IDGene Name
Hoxb5 ENSMUSG00000038700.3 Hoxb5



Activity profile for motif Hoxb5.

activity profile for motif Hoxb5


Sorted Z-values histogram for motif Hoxb5

Sorted Z-values for motif Hoxb5



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxb5

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 92 entries
PromoterScoreRefseqGene SymbolGene Name
chr5_+_125532377 15.114 ENSMUST00000031446.6
 Tmem132b
transmembrane protein 132B
chr6_-_18514802 12.167 ENSMUST00000090601.5
 Cttnbp2
cortactin binding protein 2
chr17_-_57087729 10.283 ENSMUST00000071135.5
 Tubb4a
tubulin, beta 4A class IVA
chr1_-_56971762 9.305 ENSMUST00000114415.3
 Satb2
special AT-rich sequence binding protein 2
chr17_+_35076902 7.847 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
 Ly6g6e


lymphocyte antigen 6 complex, locus G6E


chr12_-_78980758 7.839 ENSMUST00000174072.1
 Tmem229b
transmembrane protein 229B
chrX_-_165327376 7.004 ENSMUST00000058787.8
 Glra2
glycine receptor, alpha 2 subunit
chr12_-_78983476 6.880 ENSMUST00000070174.7
 Tmem229b
transmembrane protein 229B
chr11_+_74619594 6.420 ENSMUST00000100866.2
 E130309D14Rik
RIKEN cDNA E130309D14 gene
chr17_+_35077080 6.249 ENSMUST00000172959.1
 Ly6g6e
lymphocyte antigen 6 complex, locus G6E
chr2_+_158667119 5.861 ENSMUST00000045503.4
 Ppp1r16b
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr13_+_88821472 5.764 ENSMUST00000118731.1
ENSMUST00000081769.6
 Edil3

EGF-like repeats and discoidin I-like domains 3

chr13_+_88821606 5.339 ENSMUST00000043111.6
 Edil3
EGF-like repeats and discoidin I-like domains 3
chr10_-_62143906 5.154 ENSMUST00000141724.1
ENSMUST00000150057.1
 2010107G23Rik

RIKEN cDNA 2010107G23 gene

chr3_-_85722474 4.975 ENSMUST00000119077.1
 Fam160a1
family with sequence similarity 160, member A1
chr3_-_89160155 4.367 ENSMUST00000029686.3
 Hcn3
hyperpolarization-activated, cyclic nucleotide-gated K+ 3
chr5_+_117133567 4.341 ENSMUST00000179276.1
ENSMUST00000092889.5
ENSMUST00000145640.1
 Taok3


TAO kinase 3


chr2_-_153225396 4.328 ENSMUST00000099194.2
 Tspyl3
TSPY-like 3
chr7_+_3390629 4.145 ENSMUST00000182222.1
 Cacng8
calcium channel, voltage-dependent, gamma subunit 8
chr19_-_45816007 3.747 ENSMUST00000079431.3
ENSMUST00000026247.6
ENSMUST00000162528.2
 Kcnip2


Kv channel-interacting protein 2



Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 40 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 14.1 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) postsynaptic signal transduction(GO:0098926) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 11.1 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.6 9.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 8.7 GO:0030036 actin cytoskeleton organization(GO:0030036)
0.0 7.4 GO:0007017 microtubule-based process(GO:0007017)
1.0 7.0 GO:0071361 cellular response to zinc ion(GO:0071294) cellular response to ethanol(GO:0071361)
1.5 5.9 GO:1903587 regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.3 5.4 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
1.2 4.7 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.0 4.4 GO:0035725 sodium ion transmembrane transport(GO:0035725)
0.2 4.3 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.2 4.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.2 3.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.7 3.7 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.4 3.6 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 3.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 2.9 GO:0010225 response to UV-C(GO:0010225)
0.4 2.6 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 2.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 2.4 GO:0010501 RNA secondary structure unwinding(GO:0010501)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 23 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 10.3 GO:0033269 internode region of axon(GO:0033269)
0.1 9.4 GO:0008021 synaptic vesicle(GO:0008021)
0.1 9.3 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 7.2 GO:0048471 perinuclear region of cytoplasm(GO:0048471)
0.1 6.5 GO:0043204 perikaryon(GO:0043204)
0.1 5.9 GO:0034707 chloride channel complex(GO:0034707)
0.1 4.6 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.9 4.4 GO:0044316 cone cell pedicle(GO:0044316)
0.1 4.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 3.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 3.5 GO:0045171 intercellular bridge(GO:0045171)
0.3 3.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 3.3 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.3 3.1 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 2.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.3 2.4 GO:0033391 chromatoid body(GO:0033391)
0.2 2.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.9 GO:0030496 midbody(GO:0030496)
0.0 1.4 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 1.0 GO:0005776 autophagosome(GO:0005776)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 33 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.7 14.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
1.5 12.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 11.1 GO:0005178 integrin binding(GO:0005178)
0.1 10.3 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
2.3 7.0 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.3 5.9 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.8 4.7 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.9 4.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 4.5 GO:0016247 channel regulator activity(GO:0016247)
0.9 4.4 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 3.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 3.2 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 3.1 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 3.0 GO:0051015 actin filament binding(GO:0051015)
0.1 2.9 GO:0097602 cullin family protein binding(GO:0097602)
0.2 2.6 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 2.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 2.4 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 2.3 GO:0042165 neurotransmitter binding(GO:0042165)
0.0 2.2 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)