Motif ID: Hoxc10
Z-value: 0.807
Transcription factors associated with Hoxc10:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Hoxc10 | ENSMUSG00000022484.7 | Hoxc10 |
Top targets:
Gene overrepresentation in biological_process category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.2 | 15.6 | GO:0048686 | regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690) |
2.7 | 18.8 | GO:0034047 | regulation of protein phosphatase type 2A activity(GO:0034047) |
2.6 | 13.2 | GO:2000255 | negative regulation of male germ cell proliferation(GO:2000255) |
2.5 | 7.6 | GO:0043379 | memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294) |
2.3 | 9.0 | GO:1901204 | positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204) |
1.9 | 9.6 | GO:0097116 | gephyrin clustering involved in postsynaptic density assembly(GO:0097116) |
1.3 | 3.9 | GO:0014877 | response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894) |
0.9 | 4.7 | GO:0007262 | STAT protein import into nucleus(GO:0007262) |
0.6 | 1.9 | GO:0001866 | NK T cell proliferation(GO:0001866) regulation of natural killer cell proliferation(GO:0032817) positive regulation of natural killer cell proliferation(GO:0032819) |
0.6 | 1.8 | GO:0044028 | DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029) |
0.4 | 2.6 | GO:1903690 | negative regulation of wound healing, spreading of epidermal cells(GO:1903690) |
0.4 | 4.0 | GO:0021785 | branchiomotor neuron axon guidance(GO:0021785) |
0.4 | 2.2 | GO:1904936 | cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
0.4 | 1.1 | GO:0033092 | positive regulation of immature T cell proliferation in thymus(GO:0033092) positive regulation of interleukin-6 biosynthetic process(GO:0045410) |
0.4 | 4.0 | GO:0042572 | retinol metabolic process(GO:0042572) |
0.3 | 2.9 | GO:0071420 | cellular response to histamine(GO:0071420) |
0.3 | 0.6 | GO:0019805 | quinolinate biosynthetic process(GO:0019805) |
0.3 | 0.9 | GO:0002513 | tolerance induction to self antigen(GO:0002513) |
0.3 | 6.5 | GO:0007097 | nuclear migration(GO:0007097) |
0.3 | 4.3 | GO:0060218 | hematopoietic stem cell differentiation(GO:0060218) |
0.2 | 6.0 | GO:0048679 | regulation of axon regeneration(GO:0048679) |
0.2 | 2.3 | GO:0051967 | negative regulation of synaptic transmission, glutamatergic(GO:0051967) |
0.2 | 3.8 | GO:0046069 | cGMP catabolic process(GO:0046069) |
0.2 | 2.8 | GO:0001516 | prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457) |
0.1 | 0.7 | GO:0030259 | lipid glycosylation(GO:0030259) |
0.1 | 0.7 | GO:0071985 | multivesicular body sorting pathway(GO:0071985) |
0.1 | 1.7 | GO:1901898 | negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898) |
0.1 | 2.8 | GO:0032148 | activation of protein kinase B activity(GO:0032148) |
0.1 | 1.3 | GO:1901621 | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621) |
0.1 | 0.6 | GO:1902373 | negative regulation of mRNA catabolic process(GO:1902373) |
0.1 | 1.6 | GO:0043968 | histone H2A acetylation(GO:0043968) |
0.1 | 1.6 | GO:0015701 | bicarbonate transport(GO:0015701) |
0.1 | 0.5 | GO:0032196 | transposition(GO:0032196) |
0.1 | 0.7 | GO:1902231 | positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231) |
0.1 | 0.9 | GO:0010758 | regulation of macrophage chemotaxis(GO:0010758) |
0.0 | 4.1 | GO:0001578 | microtubule bundle formation(GO:0001578) |
0.0 | 0.9 | GO:0002021 | response to dietary excess(GO:0002021) |
0.0 | 1.1 | GO:0007608 | sensory perception of smell(GO:0007608) |
0.0 | 2.2 | GO:0035904 | aorta development(GO:0035904) |
0.0 | 3.3 | GO:0098780 | mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780) |
0.0 | 0.3 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
0.0 | 1.3 | GO:0043488 | regulation of mRNA stability(GO:0043488) |
0.0 | 0.6 | GO:0015813 | L-glutamate transport(GO:0015813) |
0.0 | 0.1 | GO:0035026 | leading edge cell differentiation(GO:0035026) |
0.0 | 9.3 | GO:0006397 | mRNA processing(GO:0006397) |
0.0 | 0.3 | GO:0035873 | lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879) |
0.0 | 2.8 | GO:0032496 | response to lipopolysaccharide(GO:0032496) |
0.0 | 0.4 | GO:0031648 | protein destabilization(GO:0031648) |
Gene overrepresentation in cellular_component category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
5.2 | 15.6 | GO:0072534 | perineuronal net(GO:0072534) |
1.0 | 19.1 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
0.9 | 2.6 | GO:0030981 | cortical microtubule cytoskeleton(GO:0030981) |
0.8 | 9.0 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
0.6 | 1.8 | GO:0005943 | phosphatidylinositol 3-kinase complex, class IA(GO:0005943) |
0.5 | 4.1 | GO:0097442 | CA3 pyramidal cell dendrite(GO:0097442) |
0.4 | 4.5 | GO:0030285 | integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563) |
0.4 | 2.3 | GO:0032983 | kainate selective glutamate receptor complex(GO:0032983) |
0.4 | 4.0 | GO:0002116 | semaphorin receptor complex(GO:0002116) |
0.3 | 1.6 | GO:0032777 | Piccolo NuA4 histone acetyltransferase complex(GO:0032777) |
0.2 | 13.2 | GO:0005791 | rough endoplasmic reticulum(GO:0005791) |
0.2 | 2.9 | GO:1902710 | GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711) |
0.1 | 9.6 | GO:0042734 | presynaptic membrane(GO:0042734) |
0.1 | 0.7 | GO:0032585 | multivesicular body membrane(GO:0032585) |
0.1 | 1.3 | GO:0005952 | cAMP-dependent protein kinase complex(GO:0005952) |
0.1 | 1.3 | GO:0042788 | polysomal ribosome(GO:0042788) |
0.1 | 7.6 | GO:0005657 | replication fork(GO:0005657) |
0.1 | 1.7 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
0.1 | 3.9 | GO:0019005 | SCF ubiquitin ligase complex(GO:0019005) |
0.1 | 0.4 | GO:0000836 | ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836) |
0.1 | 6.5 | GO:0042641 | actomyosin(GO:0042641) |
0.0 | 5.6 | GO:0005901 | caveola(GO:0005901) |
0.0 | 1.6 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.0 | 5.3 | GO:0031225 | anchored component of membrane(GO:0031225) |
0.0 | 0.3 | GO:0070688 | MLL5-L complex(GO:0070688) |
0.0 | 3.8 | GO:0043204 | perikaryon(GO:0043204) |
0.0 | 1.9 | GO:0016324 | apical plasma membrane(GO:0016324) |
0.0 | 0.7 | GO:0016581 | NuRD complex(GO:0016581) CHD-type complex(GO:0090545) |
0.0 | 0.6 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
0.0 | 0.1 | GO:0070022 | transforming growth factor beta receptor homodimeric complex(GO:0070022) |
Gene overrepresentation in molecular_function category:
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
3.3 | 13.2 | GO:0004667 | prostaglandin-D synthase activity(GO:0004667) |
3.0 | 9.0 | GO:0004517 | nitric-oxide synthase activity(GO:0004517) |
1.3 | 18.8 | GO:0008601 | protein phosphatase type 2A regulator activity(GO:0008601) |
1.0 | 15.6 | GO:0046625 | sphingolipid binding(GO:0046625) |
0.9 | 4.7 | GO:0038132 | neuregulin binding(GO:0038132) |
0.9 | 2.8 | GO:0050220 | prostaglandin-E synthase activity(GO:0050220) |
0.8 | 9.6 | GO:0097109 | neuroligin family protein binding(GO:0097109) |
0.7 | 2.8 | GO:0004954 | icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955) |
0.6 | 7.6 | GO:0001161 | intronic transcription regulatory region sequence-specific DNA binding(GO:0001161) |
0.6 | 4.2 | GO:0015016 | [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016) |
0.6 | 4.0 | GO:0052650 | NADP-retinol dehydrogenase activity(GO:0052650) |
0.5 | 4.1 | GO:0005519 | cytoskeletal regulatory protein binding(GO:0005519) |
0.4 | 2.3 | GO:0015277 | kainate selective glutamate receptor activity(GO:0015277) |
0.3 | 4.0 | GO:0017154 | semaphorin receptor activity(GO:0017154) |
0.2 | 4.2 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
0.2 | 2.6 | GO:0002162 | dystroglycan binding(GO:0002162) |
0.2 | 1.8 | GO:0046934 | phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) |
0.2 | 0.9 | GO:0034714 | type III transforming growth factor beta receptor binding(GO:0034714) |
0.2 | 1.3 | GO:0004691 | cAMP-dependent protein kinase activity(GO:0004691) |
0.2 | 3.8 | GO:0047555 | 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555) |
0.2 | 1.1 | GO:0004984 | olfactory receptor activity(GO:0004984) |
0.2 | 2.9 | GO:0050811 | GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811) |
0.1 | 2.8 | GO:0043422 | protein kinase B binding(GO:0043422) |
0.1 | 0.7 | GO:0047276 | N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276) |
0.1 | 1.1 | GO:0005149 | interleukin-1 receptor binding(GO:0005149) |
0.1 | 3.9 | GO:0005547 | phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547) |
0.1 | 1.6 | GO:0005452 | inorganic anion exchanger activity(GO:0005452) |
0.1 | 0.4 | GO:1904288 | BAT3 complex binding(GO:1904288) |
0.1 | 1.7 | GO:0004120 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715) |
0.0 | 6.6 | GO:0005057 | receptor signaling protein activity(GO:0005057) |
0.0 | 1.3 | GO:0017091 | AU-rich element binding(GO:0017091) |
0.0 | 0.3 | GO:0030957 | Tat protein binding(GO:0030957) |
0.0 | 0.6 | GO:0005313 | L-glutamate transmembrane transporter activity(GO:0005313) |
0.0 | 0.7 | GO:0031489 | myosin V binding(GO:0031489) |
0.0 | 1.6 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
0.0 | 4.6 | GO:0042393 | histone binding(GO:0042393) |
0.0 | 4.3 | GO:0000287 | magnesium ion binding(GO:0000287) |
0.0 | 0.3 | GO:0015129 | lactate transmembrane transporter activity(GO:0015129) |
0.0 | 0.7 | GO:0004407 | histone deacetylase activity(GO:0004407) |
0.0 | 0.6 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
0.0 | 0.6 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.0 | 0.4 | GO:0051721 | protein phosphatase 2A binding(GO:0051721) |