Motif ID: Hoxc10

Z-value: 0.807


Transcription factors associated with Hoxc10:

Gene SymbolEntrez IDGene Name
Hoxc10 ENSMUSG00000022484.7 Hoxc10



Activity profile for motif Hoxc10.

activity profile for motif Hoxc10


Sorted Z-values histogram for motif Hoxc10

Sorted Z-values for motif Hoxc10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc10

PNG image of the network

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Top targets:


Showing 1 to 20 of 88 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_+_159737510 15.574 ENSMUST00000111669.3
 Tnr
tenascin R
chr18_-_42899470 9.512 ENSMUST00000120632.1
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr18_-_42899294 9.255 ENSMUST00000117687.1
 Ppp2r2b
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr5_+_117841839 9.014 ENSMUST00000142742.2
 Nos1
nitric oxide synthase 1, neuronal
chr13_-_84064772 8.172 ENSMUST00000182477.1
 Gm17750
predicted gene, 17750
chr2_-_25469742 7.770 ENSMUST00000114259.2
ENSMUST00000015234.6
 Ptgds

prostaglandin D2 synthase (brain)

chr16_-_23988852 7.575 ENSMUST00000023151.5
 Bcl6
B cell leukemia/lymphoma 6
chr6_-_13839916 6.551 ENSMUST00000060442.7
 Gpr85
G protein-coupled receptor 85
chr11_-_79504078 6.007 ENSMUST00000164465.2
 Omg
oligodendrocyte myelin glycoprotein
chr15_+_81936753 5.714 ENSMUST00000038757.7
 Csdc2
cold shock domain containing C2, RNA binding
chr15_+_81936911 5.531 ENSMUST00000135663.1
 Csdc2
cold shock domain containing C2, RNA binding
chr17_-_91092715 5.458 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
 Nrxn1


neurexin I


chr2_-_25470031 5.432 ENSMUST00000114251.1
 Ptgds
prostaglandin D2 synthase (brain)
chr1_-_69108039 4.732 ENSMUST00000121473.1
 Erbb4
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr15_+_21111452 4.519 ENSMUST00000075132.6
 Cdh12
cadherin 12
chr15_+_92597104 4.490 ENSMUST00000035399.8
 Pdzrn4
PDZ domain containing RING finger 4
chr7_-_73537621 4.310 ENSMUST00000172704.1
 Chd2
chromodomain helicase DNA binding protein 2
chr3_+_76074270 4.297 ENSMUST00000038364.8
 Fstl5
follistatin-like 5
chr2_+_178141920 4.250 ENSMUST00000103066.3
 Phactr3
phosphatase and actin regulator 3
chr3_-_123672321 4.240 ENSMUST00000172537.1
ENSMUST00000029602.6
 Ndst3

N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.7 18.8 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
5.2 15.6 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
2.6 13.2 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
1.9 9.6 GO:0097116 gephyrin clustering involved in postsynaptic density assembly(GO:0097116)
0.0 9.3 GO:0006397 mRNA processing(GO:0006397)
2.3 9.0 GO:1901204 positive regulation of guanylate cyclase activity(GO:0031284) regulation of adrenergic receptor signaling pathway involved in heart process(GO:1901204)
2.5 7.6 GO:0043379 memory T cell differentiation(GO:0043379) negative regulation of isotype switching to IgE isotypes(GO:0048294)
0.3 6.5 GO:0007097 nuclear migration(GO:0007097)
0.2 6.0 GO:0048679 regulation of axon regeneration(GO:0048679)
0.9 4.7 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.3 4.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 4.1 GO:0001578 microtubule bundle formation(GO:0001578)
0.4 4.0 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.4 4.0 GO:0042572 retinol metabolic process(GO:0042572)
1.3 3.9 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.2 3.8 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 3.3 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
0.3 2.9 GO:0071420 cellular response to histamine(GO:0071420)
0.2 2.8 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1 2.8 GO:0032148 activation of protein kinase B activity(GO:0032148)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.0 19.1 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
5.2 15.6 GO:0072534 perineuronal net(GO:0072534)
0.2 13.2 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.1 9.6 GO:0042734 presynaptic membrane(GO:0042734)
0.8 9.0 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 7.6 GO:0005657 replication fork(GO:0005657)
0.1 6.5 GO:0042641 actomyosin(GO:0042641)
0.0 5.6 GO:0005901 caveola(GO:0005901)
0.0 5.3 GO:0031225 anchored component of membrane(GO:0031225)
0.4 4.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.5 4.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.4 4.0 GO:0002116 semaphorin receptor complex(GO:0002116)
0.1 3.9 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 3.8 GO:0043204 perikaryon(GO:0043204)
0.2 2.9 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.9 2.6 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.4 2.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 1.9 GO:0016324 apical plasma membrane(GO:0016324)
0.6 1.8 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 1.7 GO:0000930 gamma-tubulin complex(GO:0000930)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 42 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.3 18.8 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
1.0 15.6 GO:0046625 sphingolipid binding(GO:0046625)
3.3 13.2 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.8 9.6 GO:0097109 neuroligin family protein binding(GO:0097109)
3.0 9.0 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.6 7.6 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 6.6 GO:0005057 receptor signaling protein activity(GO:0005057)
0.9 4.7 GO:0038132 neuregulin binding(GO:0038132)
0.0 4.6 GO:0042393 histone binding(GO:0042393)
0.0 4.3 GO:0000287 magnesium ion binding(GO:0000287)
0.6 4.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.2 4.2 GO:0008599 protein phosphatase type 1 regulator activity(GO:0008599)
0.5 4.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.6 4.0 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.3 4.0 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 3.9 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.2 3.8 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.2 2.9 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.9 2.8 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.7 2.8 GO:0004954 icosanoid receptor activity(GO:0004953) prostanoid receptor activity(GO:0004954) prostaglandin receptor activity(GO:0004955)