Motif ID: Hoxc6

Z-value: 0.313


Transcription factors associated with Hoxc6:

Gene SymbolEntrez IDGene Name
Hoxc6 ENSMUSG00000001661.4 Hoxc6



Activity profile for motif Hoxc6.

activity profile for motif Hoxc6


Sorted Z-values histogram for motif Hoxc6

Sorted Z-values for motif Hoxc6



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc6

PNG image of the network

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Top targets:


Showing 1 to 20 of 58 entries
PromoterScoreRefseqGene SymbolGene Name
chrX_-_143933204 1.910 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chrX_-_143933089 1.593 ENSMUST00000087313.3
 Dcx
doublecortin
chr11_-_26210553 1.577 ENSMUST00000101447.3
 5730522E02Rik
RIKEN cDNA 5730522E02 gene
chr1_-_22315792 1.010 ENSMUST00000164877.1
 Rims1
regulating synaptic membrane exocytosis 1
chr3_+_5218546 0.827 ENSMUST00000026284.6
 Zfhx4
zinc finger homeodomain 4
chr3_+_5218516 0.818 ENSMUST00000175866.1
 Zfhx4
zinc finger homeodomain 4
chr6_-_65144908 0.771 ENSMUST00000031982.4
 Hpgds
hematopoietic prostaglandin D synthase
chr2_+_65620829 0.756 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr8_-_54724317 0.752 ENSMUST00000129132.2
ENSMUST00000150488.1
ENSMUST00000127511.2
 Wdr17


WD repeat domain 17


chr3_+_5218589 0.658 ENSMUST00000177488.1
 Zfhx4
zinc finger homeodomain 4
chr10_-_100589205 0.656 ENSMUST00000054471.8
 4930430F08Rik
RIKEN cDNA 4930430F08 gene
chr5_+_17574268 0.634 ENSMUST00000030568.7
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr1_+_19208914 0.542 ENSMUST00000027059.4
 Tfap2b
transcription factor AP-2 beta
chr8_-_9976294 0.528 ENSMUST00000095476.4
 Lig4
ligase IV, DNA, ATP-dependent
chr6_+_128399766 0.472 ENSMUST00000001561.5
 Nrip2
nuclear receptor interacting protein 2
chr7_+_123123870 0.460 ENSMUST00000094053.5
 Tnrc6a
trinucleotide repeat containing 6a
chr11_-_23895208 0.448 ENSMUST00000102863.2
ENSMUST00000020513.3
 Papolg

poly(A) polymerase gamma

chr10_-_53647080 0.430 ENSMUST00000169866.1
 Fam184a
family with sequence similarity 184, member A
chr19_+_11469353 0.429 ENSMUST00000165310.1
 Ms4a6c
membrane-spanning 4-domains, subfamily A, member 6C
chr3_-_113574242 0.419 ENSMUST00000142505.2
 Amy1
amylase 1, salivary

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 15 of 15 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 3.5 GO:0021860 pyramidal neuron development(GO:0021860)
0.3 1.0 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.2 0.8 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.2 0.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.6 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.0 0.6 GO:0046677 response to antibiotic(GO:0046677)
0.2 0.5 GO:0097274 urea homeostasis(GO:0097274)
0.1 0.5 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.5 GO:0045974 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.4 GO:0002074 extraocular skeletal muscle development(GO:0002074) pulmonary myocardium development(GO:0003350) subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.1 0.4 GO:0033762 response to glucagon(GO:0033762)
0.1 0.3 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:0034035 purine ribonucleoside bisphosphate metabolic process(GO:0034035)

Gene overrepresentation in cellular_component category:

Showing 1 to 8 of 8 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 1.0 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.8 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.5 GO:0032807 DNA ligase IV complex(GO:0032807)
0.1 0.5 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.5 GO:0043034 costamere(GO:0043034)
0.1 0.4 GO:0045275 respiratory chain complex III(GO:0045275)
0.1 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)

Gene overrepresentation in molecular_function category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 3.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.9 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.2 0.8 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.8 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 0.6 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.6 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.1 0.5 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.5 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.0 0.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.1 0.4 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 0.3 GO:0033192 calcium-dependent protein serine/threonine phosphatase activity(GO:0004723) calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.3 GO:0050253 prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) retinyl-palmitate esterase activity(GO:0050253) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)