Motif ID: Hoxc9

Z-value: 0.610


Transcription factors associated with Hoxc9:

Gene SymbolEntrez IDGene Name
Hoxc9 ENSMUSG00000036139.6 Hoxc9

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hoxc9mm10_v2_chr15_+_102977032_102977032-0.114.0e-01Click!


Activity profile for motif Hoxc9.

activity profile for motif Hoxc9


Sorted Z-values histogram for motif Hoxc9

Sorted Z-values for motif Hoxc9



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxc9

PNG image of the network

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Top targets:


Showing 1 to 20 of 72 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_+_102658640 3.477 ENSMUST00000080210.3
 Slc1a2
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr3_+_129199919 2.779 ENSMUST00000029657.9
ENSMUST00000106382.4
 Pitx2

paired-like homeodomain transcription factor 2

chr3_+_129199878 2.181 ENSMUST00000174661.2
 Pitx2
paired-like homeodomain transcription factor 2
chr1_+_66321708 1.854 ENSMUST00000114013.1
 Map2
microtubule-associated protein 2
chrX_+_56609751 1.840 ENSMUST00000144068.1
 Slc9a6
solute carrier family 9 (sodium/hydrogen exchanger), member 6
chr1_+_187997821 1.787 ENSMUST00000027906.6
 Esrrg
estrogen-related receptor gamma
chr4_+_136143497 1.717 ENSMUST00000008016.2
 Id3
inhibitor of DNA binding 3
chr1_+_187997835 1.692 ENSMUST00000110938.1
 Esrrg
estrogen-related receptor gamma
chr10_+_4710119 1.679 ENSMUST00000105588.1
ENSMUST00000105589.1
 Esr1

estrogen receptor 1 (alpha)

chr2_-_26516620 1.639 ENSMUST00000132820.1
 Notch1
notch 1
chr2_+_70474923 1.589 ENSMUST00000100043.2
 Sp5
trans-acting transcription factor 5
chrX_-_143933089 1.421 ENSMUST00000087313.3
 Dcx
doublecortin
chr8_-_105471481 1.357 ENSMUST00000014990.6
 Tppp3
tubulin polymerization-promoting protein family member 3
chr18_+_65582239 1.252 ENSMUST00000182684.1
 Zfp532
zinc finger protein 532
chr16_-_37384915 1.209 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
 Stxbp5l



syntaxin binding protein 5-like



chr7_-_139582790 1.084 ENSMUST00000106095.2
 Nkx6-2
NK6 homeobox 2
chr2_-_38714491 1.037 ENSMUST00000028084.4
 Nr5a1
nuclear receptor subfamily 5, group A, member 1
chr17_-_49564262 1.009 ENSMUST00000057610.6
 Daam2
dishevelled associated activator of morphogenesis 2
chrX_+_56609843 0.990 ENSMUST00000077741.5
ENSMUST00000114784.2
 Slc9a6

solute carrier family 9 (sodium/hydrogen exchanger), member 6

chr3_+_129199960 0.989 ENSMUST00000173645.2
 Pitx2
paired-like homeodomain transcription factor 2

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 30 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 5.9 GO:0002074 extraocular skeletal muscle development(GO:0002074) pulmonary myocardium development(GO:0003350) subthalamus development(GO:0021539) subthalamic nucleus development(GO:0021763) left lung morphogenesis(GO:0060460) pulmonary vein morphogenesis(GO:0060577) superior vena cava morphogenesis(GO:0060578)
0.6 3.5 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 3.3 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 2.9 GO:0001578 microtubule bundle formation(GO:0001578)
0.4 2.8 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.1 2.3 GO:0021860 pyramidal neuron development(GO:0021860)
0.4 1.7 GO:0060745 mammary gland branching involved in pregnancy(GO:0060745)
0.1 1.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 1.7 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.5 1.6 GO:0003219 atrioventricular node development(GO:0003162) cardiac right ventricle formation(GO:0003219)
0.1 1.6 GO:0036342 post-anal tail morphogenesis(GO:0036342)
0.0 1.5 GO:0046677 response to antibiotic(GO:0046677)
0.2 1.1 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
0.3 1.0 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.0 1.0 GO:0007368 determination of left/right symmetry(GO:0007368)
0.2 0.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.7 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 0.6 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.1 0.6 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.6 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)

Gene overrepresentation in cellular_component category:

Showing 1 to 16 of 16 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.0 GO:0005667 transcription factor complex(GO:0005667)
0.1 3.5 GO:0030673 axolemma(GO:0030673)
0.5 2.8 GO:0044308 axonal spine(GO:0044308)
0.1 2.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 1.9 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 1.7 GO:0031201 SNARE complex(GO:0031201)
0.3 1.6 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 1.5 GO:0016607 nuclear speck(GO:0016607)
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 0.6 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0005587 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)
0.0 0.2 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.2 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.0 GO:0071914 prominosome(GO:0071914)

Gene overrepresentation in molecular_function category:

Showing 1 to 18 of 18 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 5.9 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.9 3.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 3.5 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.4 2.8 GO:0005451 monovalent cation:proton antiporter activity(GO:0005451) sodium:proton antiporter activity(GO:0015385) potassium:proton antiporter activity(GO:0015386)
0.1 2.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.2 1.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.6 1.7 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.0 1.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 1.7 GO:0019905 syntaxin binding(GO:0019905)
0.1 1.6 GO:0098811 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 1.1 GO:0004879 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.2 0.6 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.3 GO:0038025 reelin receptor activity(GO:0038025)
0.1 0.3 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)