Motif ID: Hoxd1

Z-value: 0.618


Transcription factors associated with Hoxd1:

Gene SymbolEntrez IDGene Name
Hoxd1 ENSMUSG00000042448.4 Hoxd1



Activity profile for motif Hoxd1.

activity profile for motif Hoxd1


Sorted Z-values histogram for motif Hoxd1

Sorted Z-values for motif Hoxd1



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd1

PNG image of the network

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Top targets:


Showing 1 to 20 of 149 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_156392829 5.651 ENSMUST00000088578.2
 2900097C17Rik
RIKEN cDNA 2900097C17 gene
chr15_-_8710409 3.966 ENSMUST00000157065.1
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrX_-_143933204 3.588 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
 Dcx


doublecortin


chr15_-_8710734 3.524 ENSMUST00000005493.7
 Slc1a3
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chrX_-_143933089 3.510 ENSMUST00000087313.3
 Dcx
doublecortin
chr10_-_110000219 2.841 ENSMUST00000032719.7
 Nav3
neuron navigator 3
chr2_+_116067213 2.728 ENSMUST00000152412.1
 G630016G05Rik
RIKEN cDNA G630016G05 gene
chr5_-_62766153 2.711 ENSMUST00000076623.4
 Arap2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_+_170731807 2.595 ENSMUST00000029075.4
 Dok5
docking protein 5
chr9_-_55919605 2.549 ENSMUST00000037408.8
 Scaper
S phase cyclin A-associated protein in the ER
chr2_+_119047129 2.511 ENSMUST00000153300.1
ENSMUST00000028799.5
 Casc5

cancer susceptibility candidate 5

chr13_+_83732438 2.499 ENSMUST00000182701.1
 C130071C03Rik
RIKEN cDNA C130071C03 gene
chr12_-_24493656 2.470 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr2_-_20943413 2.457 ENSMUST00000140230.1
 Arhgap21
Rho GTPase activating protein 21
chr5_+_107497762 2.454 ENSMUST00000152474.1
ENSMUST00000060553.7
 A830010M20Rik

RIKEN cDNA A830010M20 gene

chr1_-_158356258 2.421 ENSMUST00000004133.8
 Brinp2
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr13_-_105054895 2.361 ENSMUST00000063551.5
 Rgs7bp
regulator of G-protein signalling 7 binding protein
chrX_+_9885622 2.228 ENSMUST00000067529.2
ENSMUST00000086165.3
 Sytl5

synaptotagmin-like 5

chr12_+_52699297 2.066 ENSMUST00000095737.3
 Akap6
A kinase (PRKA) anchor protein 6
chr5_+_107497718 2.047 ENSMUST00000112671.2
 A830010M20Rik
RIKEN cDNA A830010M20 gene

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 58 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 7.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.4 7.1 GO:0021860 pyramidal neuron development(GO:0021860)
0.2 3.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.2 2.6 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.5 2.5 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 2.4 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.6 2.3 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 2.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.5 2.1 GO:0032512 regulation of protein phosphatase type 2B activity(GO:0032512) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.2 2.1 GO:1902018 negative regulation of cilium assembly(GO:1902018)
0.3 1.9 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.2 1.9 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.4 1.8 GO:0051661 maintenance of centrosome location(GO:0051661)
0.1 1.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 1.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.6 1.7 GO:0019085 early viral transcription(GO:0019085)
0.6 1.7 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.2 1.7 GO:0019532 oxalate transport(GO:0019532)
0.3 1.6 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.1 1.6 GO:0032288 myelin assembly(GO:0032288)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 9.5 GO:0030425 dendrite(GO:0030425)
0.4 7.5 GO:0043205 fibril(GO:0043205)
0.1 4.7 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 2.2 GO:0070382 exocytic vesicle(GO:0070382)
0.1 2.1 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 1.9 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.4 1.8 GO:0036449 microtubule minus-end(GO:0036449)
0.1 1.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.6 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 1.6 GO:1902710 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)
0.0 1.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.3 GO:0030175 filopodium(GO:0030175)
0.1 1.1 GO:0071439 clathrin complex(GO:0071439)
0.0 1.1 GO:0005776 autophagosome(GO:0005776)
0.0 1.0 GO:0031519 PcG protein complex(GO:0031519)
0.1 0.9 GO:0097524 sperm plasma membrane(GO:0097524)
0.1 0.9 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.0 0.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.7 GO:0070469 respiratory chain(GO:0070469)
0.1 0.6 GO:0034464 BBSome(GO:0034464)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.5 7.5 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.3 7.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 3.9 GO:0030276 clathrin binding(GO:0030276)
0.1 3.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.1 3.0 GO:0005158 insulin receptor binding(GO:0005158)
0.1 2.7 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.3 2.1 GO:0043495 protein anchor(GO:0043495)
0.1 2.0 GO:0017161 phosphohistidine phosphatase activity(GO:0008969) inositol-1,3,4-trisphosphate 4-phosphatase activity(GO:0017161) NADP phosphatase activity(GO:0019178) 5-amino-6-(5-phosphoribitylamino)uracil phosphatase activity(GO:0043726) phosphatidylinositol-3,5-bisphosphate 5-phosphatase activity(GO:0043813) inositol-1,3,4,5,6-pentakisphosphate 1-phosphatase activity(GO:0052825) inositol-3,4-bisphosphate 4-phosphatase activity(GO:0052828) inositol-1,3,4-trisphosphate 1-phosphatase activity(GO:0052829) inositol-1,3,4,6-tetrakisphosphate 6-phosphatase activity(GO:0052830) inositol-1,3,4,6-tetrakisphosphate 1-phosphatase activity(GO:0052831) phosphatidylinositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052867) IDP phosphatase activity(GO:1990003)
0.6 1.9 GO:0001588 dopamine neurotransmitter receptor activity, coupled via Gs(GO:0001588)
0.2 1.9 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 1.8 GO:0030552 cAMP binding(GO:0030552)
0.2 1.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.2 1.7 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.2 1.6 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 1.6 GO:0050811 GABA-A receptor activity(GO:0004890) GABA receptor binding(GO:0050811)
0.0 1.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 1.6 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 1.3 GO:0005351 sugar:proton symporter activity(GO:0005351)
0.0 1.3 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)