Motif ID: Hoxd10

Z-value: 0.490


Transcription factors associated with Hoxd10:

Gene SymbolEntrez IDGene Name
Hoxd10 ENSMUSG00000050368.3 Hoxd10



Activity profile for motif Hoxd10.

activity profile for motif Hoxd10


Sorted Z-values histogram for motif Hoxd10

Sorted Z-values for motif Hoxd10



Network of associatons between targets according to the STRING database.



First level regulatory network of Hoxd10

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr8_-_84773381 9.529 ENSMUST00000109764.1
 Nfix
nuclear factor I/X
chr9_+_27790947 8.346 ENSMUST00000115243.2
 Opcml
opioid binding protein/cell adhesion molecule-like
chr3_-_80802789 6.401 ENSMUST00000107745.1
ENSMUST00000075316.4
 Gria2

glutamate receptor, ionotropic, AMPA2 (alpha 2)

chr4_+_102254993 3.774 ENSMUST00000106908.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr3_+_55461758 2.978 ENSMUST00000070418.4
 Dclk1
doublecortin-like kinase 1
chrX_+_66653003 2.972 ENSMUST00000036043.4
 Slitrk2
SLIT and NTRK-like family, member 2
chr18_-_78123324 2.788 ENSMUST00000160292.1
ENSMUST00000091813.5
 Slc14a1

solute carrier family 14 (urea transporter), member 1

chrX_-_70365052 2.498 ENSMUST00000101509.2
 Ids
iduronate 2-sulfatase
chr8_-_109251698 2.422 ENSMUST00000079189.3
 4922502B01Rik
RIKEN cDNA 4922502B01 gene
chr7_+_96210107 2.198 ENSMUST00000138760.1
 Tenm4
teneurin transmembrane protein 4
chr2_+_65620829 2.015 ENSMUST00000028377.7
 Scn2a1
sodium channel, voltage-gated, type II, alpha 1
chr15_+_9140527 1.857 ENSMUST00000090380.4
 Lmbrd2
LMBR1 domain containing 2
chr7_+_30095150 1.529 ENSMUST00000130526.1
ENSMUST00000108200.1
 Zfp260

zinc finger protein 260

chr2_+_106693185 1.309 ENSMUST00000111063.1
 Mpped2
metallophosphoesterase domain containing 2
chr10_+_69534039 1.122 ENSMUST00000182557.1
 Ank3
ankyrin 3, epithelial
chr17_+_78508063 1.119 ENSMUST00000024880.9
 Vit
vitrin
chr2_+_21367532 1.111 ENSMUST00000055946.7
 Gpr158
G protein-coupled receptor 158
chr3_+_86084434 1.075 ENSMUST00000107664.2
 Sh3d19
SH3 domain protein D19
chr9_+_95857597 1.031 ENSMUST00000034980.7
 Atr
ataxia telangiectasia and Rad3 related
chr10_-_49783259 1.030 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
 Grik2



glutamate receptor, ionotropic, kainate 2 (beta 2)



chr9_+_104569671 0.996 ENSMUST00000057742.8
 Cpne4
copine IV
chr6_+_33249085 0.972 ENSMUST00000052266.8
ENSMUST00000090381.4
ENSMUST00000115080.1
 Exoc4


exocyst complex component 4


chr1_+_180111339 0.957 ENSMUST00000145181.1
 Cdc42bpa
CDC42 binding protein kinase alpha
chr14_-_93888732 0.915 ENSMUST00000068992.2
 Pcdh9
protocadherin 9
chr6_-_28397999 0.837 ENSMUST00000035930.4
 Zfp800
zinc finger protein 800
chr10_+_116177351 0.689 ENSMUST00000155606.1
ENSMUST00000128399.1
 Ptprr

protein tyrosine phosphatase, receptor type, R

chr7_-_73541738 0.674 ENSMUST00000169922.2
 Chd2
chromodomain helicase DNA binding protein 2
chr17_-_46327949 0.569 ENSMUST00000047970.7
 Abcc10
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr18_-_6490808 0.499 ENSMUST00000028100.6
ENSMUST00000050542.5
 Epc1

enhancer of polycomb homolog 1 (Drosophila)

chr17_-_78684262 0.491 ENSMUST00000145480.1
 Strn
striatin, calmodulin binding protein
chr4_+_43401232 0.407 ENSMUST00000125399.1
 Rusc2
RUN and SH3 domain containing 2
chr15_+_57912199 0.359 ENSMUST00000022992.6
 Tbc1d31
TBC1 domain family, member 31
chr4_+_19605451 0.351 ENSMUST00000108250.2
 Gm12353
predicted gene 12353
chr14_-_87141114 0.234 ENSMUST00000168889.1
 Diap3
diaphanous homolog 3 (Drosophila)
chr13_+_49582745 0.233 ENSMUST00000065494.7
 Omd
osteomodulin
chr1_-_152625212 0.212 ENSMUST00000027760.7
 Rgl1
ral guanine nucleotide dissociation stimulator,-like 1
chr12_+_76417598 0.122 ENSMUST00000063977.7
 Ppp1r36
protein phosphatase 1, regulatory subunit 36
chr12_+_55089202 0.116 ENSMUST00000021407.10
 Srp54a
signal recognition particle 54A
chr1_-_132390301 0.101 ENSMUST00000132435.1
 Tmcc2
transmembrane and coiled-coil domains 2
chr18_-_75697639 0.074 ENSMUST00000165559.1
 Ctif
CBP80/20-dependent translation initiation factor

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.5 2.2 GO:0032289 central nervous system myelin formation(GO:0032289) cardiac cell fate specification(GO:0060912)
0.5 2.0 GO:0008627 intrinsic apoptotic signaling pathway in response to osmotic stress(GO:0008627)
0.4 2.8 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.3 1.0 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.3 6.4 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.3 3.8 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 0.7 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 1.0 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.1 1.0 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 1.1 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.1 3.0 GO:0021952 central nervous system projection neuron axonogenesis(GO:0021952)
0.0 1.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 1.0 GO:0007097 nuclear migration(GO:0007097)
0.0 0.7 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.5 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 2.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.4 GO:0032279 asymmetric synapse(GO:0032279)
0.2 1.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.2 3.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.0 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.0 GO:0032584 growth cone membrane(GO:0032584)
0.1 1.1 GO:0005614 interstitial matrix(GO:0005614)
0.1 1.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 1.0 GO:0001741 XY body(GO:0001741)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786) signal recognition particle(GO:0048500)
0.0 0.9 GO:0044291 cell-cell contact zone(GO:0044291)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 7.4 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.5 2.8 GO:0015265 urea channel activity(GO:0015265)
0.2 2.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.2 1.0 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.2 2.0 GO:0043522 leucine zipper domain binding(GO:0043522)
0.1 3.8 GO:0030552 cAMP binding(GO:0030552)
0.0 1.1 GO:0070064 proline-rich region binding(GO:0070064)
0.0 1.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 1.3 GO:0044824 integrase activity(GO:0008907) T/G mismatch-specific endonuclease activity(GO:0043765) retroviral integrase activity(GO:0044823) retroviral 3' processing activity(GO:0044824)
0.0 0.5 GO:0070016 armadillo repeat domain binding(GO:0070016)