Motif ID: Hsf2

Z-value: 2.296


Transcription factors associated with Hsf2:

Gene SymbolEntrez IDGene Name
Hsf2 ENSMUSG00000019878.7 Hsf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Hsf2mm10_v2_chr10_+_57486354_57486414-0.273.8e-02Click!


Activity profile for motif Hsf2.

activity profile for motif Hsf2


Sorted Z-values histogram for motif Hsf2

Sorted Z-values for motif Hsf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Hsf2

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr14_-_48667508 22.652 ENSMUST00000144465.1
ENSMUST00000133479.1
ENSMUST00000119070.1
ENSMUST00000152018.1
Otx2



orthodenticle homolog 2 (Drosophila)



chr17_-_70851189 20.610 ENSMUST00000059775.8
Tgif1
TGFB-induced factor homeobox 1
chr17_-_25797032 18.994 ENSMUST00000165838.1
ENSMUST00000002344.6
Metrn

meteorin, glial cell differentiation regulator

chr17_-_70849644 17.115 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
Tgif1


TGFB-induced factor homeobox 1


chr10_-_92164666 16.852 ENSMUST00000183123.1
ENSMUST00000182033.1
Rmst

rhabdomyosarcoma 2 associated transcript (non-coding RNA)

chr2_+_120463566 14.983 ENSMUST00000028749.7
ENSMUST00000110721.1
Capn3

calpain 3

chr12_-_56536895 14.321 ENSMUST00000001536.8
Nkx2-1
NK2 homeobox 1
chr14_+_19751257 14.258 ENSMUST00000022340.3
Nid2
nidogen 2
chr7_-_4752972 13.330 ENSMUST00000183971.1
ENSMUST00000182173.1
ENSMUST00000182738.1
ENSMUST00000184143.1
ENSMUST00000182111.1
ENSMUST00000182048.1
ENSMUST00000063324.7
Cox6b2






cytochrome c oxidase subunit VIb polypeptide 2






chr11_+_120949053 12.951 ENSMUST00000154187.1
ENSMUST00000100130.3
ENSMUST00000129473.1
ENSMUST00000168579.1
Slc16a3



solute carrier family 16 (monocarboxylic acid transporters), member 3



chr9_+_65141154 12.399 ENSMUST00000034961.4
Igdcc3
immunoglobulin superfamily, DCC subclass, member 3
chr1_-_72874877 12.158 ENSMUST00000027377.8
Igfbp5
insulin-like growth factor binding protein 5
chr17_-_58991343 11.881 ENSMUST00000025064.7
2610034M16Rik
RIKEN cDNA 2610034M16 gene
chr10_+_84838143 11.793 ENSMUST00000095388.4
Rfx4
regulatory factor X, 4 (influences HLA class II expression)
chr5_+_92603039 11.567 ENSMUST00000050952.3
Stbd1
starch binding domain 1
chr11_-_11970540 11.490 ENSMUST00000109653.1
Grb10
growth factor receptor bound protein 10
chr12_-_10900296 11.414 ENSMUST00000085735.2
Pgk1-rs7
phosphoglycerate kinase-1, related sequence-7
chr5_-_5514730 10.985 ENSMUST00000115445.1
ENSMUST00000179804.1
ENSMUST00000125110.1
ENSMUST00000115446.1
Cldn12



claudin 12



chr6_-_72235559 10.851 ENSMUST00000042646.7
Atoh8
atonal homolog 8 (Drosophila)
chr6_-_119467210 10.777 ENSMUST00000118120.1
Wnt5b
wingless-related MMTV integration site 5B
chr7_+_16781341 10.687 ENSMUST00000108496.2
Slc1a5
solute carrier family 1 (neutral amino acid transporter), member 5
chr10_+_121033960 10.507 ENSMUST00000020439.4
ENSMUST00000175867.1
Wif1

Wnt inhibitory factor 1

chr9_+_7764041 10.480 ENSMUST00000052865.9
Tmem123
transmembrane protein 123
chr18_+_50053282 10.338 ENSMUST00000148159.2
Tnfaip8
tumor necrosis factor, alpha-induced protein 8
chr5_-_5514873 10.315 ENSMUST00000060947.7
Cldn12
claudin 12
chrX_-_75843063 10.291 ENSMUST00000114057.1
Pls3
plastin 3 (T-isoform)
chr13_+_51645232 10.226 ENSMUST00000075853.5
Cks2
CDC28 protein kinase regulatory subunit 2
chr10_-_78591945 10.180 ENSMUST00000040580.6
Syde1
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr3_+_27984145 10.107 ENSMUST00000067757.4
Pld1
phospholipase D1
chr6_-_95718800 10.107 ENSMUST00000079847.5
Suclg2
succinate-Coenzyme A ligase, GDP-forming, beta subunit
chr1_-_133424377 10.021 ENSMUST00000153799.1
Sox13
SRY-box containing gene 13
chr13_+_98354234 9.869 ENSMUST00000105098.3
Foxd1
forkhead box D1
chr2_+_30061754 9.831 ENSMUST00000149578.1
ENSMUST00000102866.3
Set

SET nuclear oncogene

chr15_+_78926720 9.740 ENSMUST00000089377.5
Lgals1
lectin, galactose binding, soluble 1
chr17_+_47593444 9.642 ENSMUST00000182209.1
Ccnd3
cyclin D3
chr5_+_92683625 9.640 ENSMUST00000168878.1
Shroom3
shroom family member 3
chr2_+_52038005 9.550 ENSMUST00000065927.5
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr1_+_12692430 9.540 ENSMUST00000180062.1
ENSMUST00000177608.1
Sulf1

sulfatase 1

chr13_-_3918157 9.510 ENSMUST00000091853.4
Net1
neuroepithelial cell transforming gene 1
chr5_-_116422858 9.463 ENSMUST00000036991.4
Hspb8
heat shock protein 8
chr5_-_100820929 9.428 ENSMUST00000117364.1
ENSMUST00000055245.6
Fam175a

family with sequence similarity 175, member A

chr11_+_43528759 9.401 ENSMUST00000050574.6
Ccnjl
cyclin J-like
chr6_-_92943485 9.286 ENSMUST00000113438.1
Adamts9
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 9
chr2_+_71389239 9.027 ENSMUST00000028408.2
Hat1
histone aminotransferase 1
chr9_-_114781986 8.877 ENSMUST00000035009.8
ENSMUST00000084867.7
Cmtm7

CKLF-like MARVEL transmembrane domain containing 7

chr7_-_120982260 8.610 ENSMUST00000033169.8
Cdr2
cerebellar degeneration-related 2
chr17_-_70851710 8.563 ENSMUST00000166395.2
Tgif1
TGFB-induced factor homeobox 1
chr2_-_28466266 8.536 ENSMUST00000127683.1
ENSMUST00000086370.4
1700007K13Rik

RIKEN cDNA 1700007K13 gene

chr19_-_10203880 8.524 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
Fen1



flap structure specific endonuclease 1



chr10_+_128238034 8.446 ENSMUST00000105245.2
Timeless
timeless circadian clock 1
chr4_+_62965560 8.376 ENSMUST00000030043.6
ENSMUST00000107415.1
ENSMUST00000064814.5
Zfp618


zinc finger protein 618


chr6_+_56832059 8.309 ENSMUST00000031795.7
Fkbp9
FK506 binding protein 9
chr5_-_50058908 8.147 ENSMUST00000030971.5
Gpr125
G protein-coupled receptor 125
chr2_+_30845059 8.042 ENSMUST00000041659.5
Prrx2
paired related homeobox 2
chr9_-_100571049 8.040 ENSMUST00000093792.2
Slc35g2
solute carrier family 35, member G2
chr4_+_57845240 8.028 ENSMUST00000102903.1
ENSMUST00000107598.3
Akap2

A kinase (PRKA) anchor protein 2

chr12_-_91746020 7.951 ENSMUST00000166967.1
Ston2
stonin 2
chr2_+_91256144 7.892 ENSMUST00000154959.1
ENSMUST00000059566.4
Pacsin3

protein kinase C and casein kinase substrate in neurons 3

chr5_-_24730635 7.892 ENSMUST00000068693.5
Wdr86
WD repeat domain 86
chr11_+_114851507 7.878 ENSMUST00000177952.1
Gprc5c
G protein-coupled receptor, family C, group 5, member C
chr17_-_15375969 7.872 ENSMUST00000014917.7
Dll1
delta-like 1 (Drosophila)
chr12_-_69228167 7.812 ENSMUST00000021359.5
Pole2
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr9_+_44134562 7.732 ENSMUST00000034650.8
ENSMUST00000098852.2
Mcam

melanoma cell adhesion molecule

chr6_-_128438673 7.723 ENSMUST00000032508.4
Fkbp4
FK506 binding protein 4
chr2_+_25180737 7.641 ENSMUST00000104999.2
Nrarp
Notch-regulated ankyrin repeat protein
chr15_+_25773985 7.536 ENSMUST00000125667.1
Myo10
myosin X
chr9_-_97018823 7.514 ENSMUST00000055433.4
Spsb4
splA/ryanodine receptor domain and SOCS box containing 4
chr18_-_53418004 7.376 ENSMUST00000025419.7
Ppic
peptidylprolyl isomerase C
chr1_-_55088024 7.269 ENSMUST00000027123.8
Hspd1
heat shock protein 1 (chaperonin)
chrX_+_52791179 7.258 ENSMUST00000101588.1
Ccdc160
coiled-coil domain containing 160
chr19_-_41206774 7.258 ENSMUST00000025986.7
ENSMUST00000169941.1
Tll2

tolloid-like 2

chr7_-_99353104 7.232 ENSMUST00000169437.1
ENSMUST00000094154.4
Serpinh1

serine (or cysteine) peptidase inhibitor, clade H, member 1

chr2_+_91255954 7.204 ENSMUST00000134699.1
Pacsin3
protein kinase C and casein kinase substrate in neurons 3
chr8_-_107403197 7.196 ENSMUST00000003947.8
Nqo1
NAD(P)H dehydrogenase, quinone 1
chr2_+_130277157 7.099 ENSMUST00000028890.8
ENSMUST00000159373.1
Nop56

NOP56 ribonucleoprotein

chr1_-_79858627 6.991 ENSMUST00000027467.4
Serpine2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr4_+_154960915 6.954 ENSMUST00000049621.6
Hes5
hairy and enhancer of split 5 (Drosophila)
chr6_+_65381294 6.869 ENSMUST00000170608.1
C130060K24Rik
RIKEN cDNA C130060K24 gene
chr19_+_25505618 6.790 ENSMUST00000025755.4
Dmrt1
doublesex and mab-3 related transcription factor 1
chr1_+_136467958 6.618 ENSMUST00000047817.6
Kif14
kinesin family member 14
chr5_+_7179299 6.612 ENSMUST00000179460.1
Tubb4b-ps1
tubulin, beta 4B class IVB, pseudogene 1
chr2_+_152847961 6.574 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
Tpx2


TPX2, microtubule-associated protein homolog (Xenopus laevis)


chr10_+_128225830 6.570 ENSMUST00000026455.7
Mip
major intrinsic protein of eye lens fiber
chr9_+_72438519 6.565 ENSMUST00000184604.1
Mns1
meiosis-specific nuclear structural protein 1
chr5_+_77310147 6.554 ENSMUST00000031167.5
Polr2b
polymerase (RNA) II (DNA directed) polypeptide B
chr2_+_152847993 6.514 ENSMUST00000028969.8
Tpx2
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr18_+_61953048 6.402 ENSMUST00000051720.5
Sh3tc2
SH3 domain and tetratricopeptide repeats 2
chr11_+_115564434 6.350 ENSMUST00000021085.4
Nup85
nucleoporin 85
chr10_-_80421847 6.297 ENSMUST00000156244.1
Tcf3
transcription factor 3
chr13_-_92794809 6.282 ENSMUST00000022213.7
Thbs4
thrombospondin 4
chr1_-_193273099 6.259 ENSMUST00000009777.2
G0s2
G0/G1 switch gene 2
chr11_-_89302545 6.208 ENSMUST00000061728.3
Nog
noggin
chr16_-_45844303 6.190 ENSMUST00000036355.6
Phldb2
pleckstrin homology-like domain, family B, member 2
chr16_-_45844228 6.181 ENSMUST00000076333.5
Phldb2
pleckstrin homology-like domain, family B, member 2
chr8_+_92357787 6.081 ENSMUST00000034184.10
Irx5
Iroquois related homeobox 5 (Drosophila)
chr2_+_59612034 6.074 ENSMUST00000112568.1
ENSMUST00000037526.4
Tanc1

tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1

chr7_+_127211608 5.991 ENSMUST00000032910.6
Mylpf
myosin light chain, phosphorylatable, fast skeletal muscle
chr11_+_26387194 5.956 ENSMUST00000109509.1
ENSMUST00000136830.1
Fancl

Fanconi anemia, complementation group L

chr9_-_77544870 5.946 ENSMUST00000183873.1
Lrrc1
leucine rich repeat containing 1
chr3_+_125404072 5.908 ENSMUST00000173932.1
Ndst4
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr18_-_80986578 5.881 ENSMUST00000057950.7
Sall3
sal-like 3 (Drosophila)
chr18_-_47368446 5.878 ENSMUST00000076043.6
ENSMUST00000135790.1
Sema6a

sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A

chr4_-_147936713 5.852 ENSMUST00000105712.1
ENSMUST00000019199.7
Plod1

procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1

chr13_-_102958084 5.824 ENSMUST00000099202.3
ENSMUST00000172264.1
Mast4

microtubule associated serine/threonine kinase family member 4

chr17_+_47505149 5.790 ENSMUST00000183177.1
ENSMUST00000182848.1
Ccnd3

cyclin D3

chr9_+_15520830 5.788 ENSMUST00000178999.1
Smco4
single-pass membrane protein with coiled-coil domains 4
chr1_-_17097839 5.765 ENSMUST00000038382.4
Jph1
junctophilin 1
chr4_-_107923519 5.715 ENSMUST00000106719.1
ENSMUST00000106720.2
ENSMUST00000131644.1
ENSMUST00000030345.8
Cpt2



carnitine palmitoyltransferase 2



chr7_+_75610038 5.684 ENSMUST00000125771.1
Akap13
A kinase (PRKA) anchor protein 13
chr6_+_66896397 5.639 ENSMUST00000043148.6
ENSMUST00000114228.1
ENSMUST00000114227.1
ENSMUST00000114226.1
ENSMUST00000114225.1
ENSMUST00000114224.1
Gng12





guanine nucleotide binding protein (G protein), gamma 12





chr2_-_151039363 5.629 ENSMUST00000066640.4
ENSMUST00000128627.1
Nanp
Ninl
N-acetylneuraminic acid phosphatase
ninein-like
chr6_+_72598475 5.607 ENSMUST00000070597.6
ENSMUST00000176364.1
ENSMUST00000176168.1
Retsat


retinol saturase (all trans retinol 13,14 reductase)


chr10_-_92165159 5.470 ENSMUST00000182567.1
ENSMUST00000181604.2
ENSMUST00000181213.1
Rmst


rhabdomyosarcoma 2 associated transcript (non-coding RNA)


chr8_+_95633500 5.414 ENSMUST00000034094.9
Gins3
GINS complex subunit 3 (Psf3 homolog)
chr5_-_149051604 5.409 ENSMUST00000093196.4
Hmgb1
high mobility group box 1
chr10_-_23349887 5.327 ENSMUST00000074366.6
ENSMUST00000092665.4
Eya4

eyes absent 4 homolog (Drosophila)

chr2_-_26503814 5.317 ENSMUST00000028288.4
Notch1
notch 1
chr2_-_172370506 5.301 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
Aurka


aurora kinase A


chr1_-_121567906 5.251 ENSMUST00000001724.5
Ddx18
DEAD (Asp-Glu-Ala-Asp) box polypeptide 18
chr4_+_59626189 5.239 ENSMUST00000070150.4
ENSMUST00000052420.6
E130308A19Rik

RIKEN cDNA E130308A19 gene

chr18_-_61259987 5.214 ENSMUST00000170335.2
Rps2-ps10
ribosomal protein S2, pseudogene 10
chr7_-_118995211 5.093 ENSMUST00000008878.8
Gprc5b
G protein-coupled receptor, family C, group 5, member B
chr19_+_6363896 5.081 ENSMUST00000113487.1
Sf1
splicing factor 1
chr6_+_29853746 5.070 ENSMUST00000064872.6
ENSMUST00000152581.1
ENSMUST00000176265.1
ENSMUST00000154079.1
Ahcyl2



S-adenosylhomocysteine hydrolase-like 2



chr6_+_104492790 5.052 ENSMUST00000161446.1
ENSMUST00000161070.1
ENSMUST00000089215.5
Cntn6


contactin 6


chr9_-_77544829 5.009 ENSMUST00000183734.1
Lrrc1
leucine rich repeat containing 1
chr4_-_41695442 4.987 ENSMUST00000102961.3
ENSMUST00000064443.6
Cntfr

ciliary neurotrophic factor receptor

chr4_+_128883549 4.978 ENSMUST00000035667.8
Trim62
tripartite motif-containing 62
chr7_-_25250720 4.960 ENSMUST00000116343.2
ENSMUST00000045847.8
Erf

Ets2 repressor factor

chr2_-_157135112 4.939 ENSMUST00000139263.1
Samhd1
SAM domain and HD domain, 1
chr4_-_43030440 4.915 ENSMUST00000135660.1
Stoml2
stomatin (Epb7.2)-like 2
chr4_-_106799779 4.901 ENSMUST00000145061.1
ENSMUST00000102762.3
Acot11

acyl-CoA thioesterase 11

chr1_-_119053619 4.808 ENSMUST00000062483.8
Gli2
GLI-Kruppel family member GLI2
chr18_-_24020307 4.771 ENSMUST00000153337.1
ENSMUST00000148525.1
Zfp191

zinc finger protein 191

chr4_+_109407087 4.763 ENSMUST00000064129.7
ENSMUST00000106619.1
Ttc39a

tetratricopeptide repeat domain 39A

chr6_+_134035691 4.737 ENSMUST00000081028.6
ENSMUST00000111963.1
Etv6

ets variant gene 6 (TEL oncogene)

chr1_-_44101661 4.736 ENSMUST00000152239.1
Tex30
testis expressed 30
chr17_-_28517509 4.730 ENSMUST00000114792.1
ENSMUST00000177939.1
Fkbp5

FK506 binding protein 5

chr2_-_91931675 4.729 ENSMUST00000111309.1
Mdk
midkine
chr1_-_45503282 4.707 ENSMUST00000086430.4
Col5a2
collagen, type V, alpha 2
chr4_+_107066985 4.690 ENSMUST00000106758.1
ENSMUST00000145324.1
ENSMUST00000106760.1
Cyb5rl


cytochrome b5 reductase-like


chr2_-_154892887 4.686 ENSMUST00000099173.4
Eif2s2
eukaryotic translation initiation factor 2, subunit 2 (beta)
chr17_+_47505211 4.678 ENSMUST00000182935.1
ENSMUST00000182506.1
Ccnd3

cyclin D3

chr5_-_23783700 4.660 ENSMUST00000119946.1
Pus7
pseudouridylate synthase 7 homolog (S. cerevisiae)
chr7_+_107370728 4.631 ENSMUST00000137663.1
ENSMUST00000073459.5
Syt9

synaptotagmin IX

chr2_-_91931696 4.616 ENSMUST00000090602.5
Mdk
midkine
chr17_+_47593516 4.611 ENSMUST00000182874.1
Ccnd3
cyclin D3
chr9_+_21546842 4.588 ENSMUST00000034703.8
ENSMUST00000115395.3
ENSMUST00000115394.1
Carm1


coactivator-associated arginine methyltransferase 1


chr4_-_86669492 4.584 ENSMUST00000149700.1
Plin2
perilipin 2
chr12_+_75308308 4.530 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
Rhoj


ras homolog gene family, member J


chr3_+_86224665 4.493 ENSMUST00000107635.1
Lrba
LPS-responsive beige-like anchor
chr17_+_36958571 4.485 ENSMUST00000040177.6
Znrd1as
Znrd1 antisense
chr6_-_30896735 4.437 ENSMUST00000048774.6
ENSMUST00000166192.1
ENSMUST00000135230.1
Copg2


coatomer protein complex, subunit gamma 2


chr2_+_31759932 4.369 ENSMUST00000028190.6
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr17_-_25727364 4.363 ENSMUST00000170070.1
ENSMUST00000048054.7
Chtf18

CTF18, chromosome transmission fidelity factor 18

chrX_+_56779699 4.354 ENSMUST00000114772.2
ENSMUST00000114768.3
ENSMUST00000155882.1
Fhl1


four and a half LIM domains 1


chr5_-_149636164 4.353 ENSMUST00000076410.4
Hsph1
heat shock 105kDa/110kDa protein 1
chrX_-_74246364 4.348 ENSMUST00000130007.1
Flna
filamin, alpha
chr7_-_141443314 4.342 ENSMUST00000106005.2
Lrdd
leucine-rich and death domain containing
chr9_-_71592265 4.337 ENSMUST00000169573.1
ENSMUST00000166843.1
ENSMUST00000163998.1
Myzap
Gcom1

myocardial zonula adherens protein
GRINL1A complex locus

chr7_+_112679327 4.331 ENSMUST00000106638.2
Tead1
TEA domain family member 1
chr18_+_60925644 4.330 ENSMUST00000115297.1
Camk2a
calcium/calmodulin-dependent protein kinase II alpha
chr2_+_29889785 4.301 ENSMUST00000113763.1
ENSMUST00000113757.1
ENSMUST00000113756.1
ENSMUST00000133233.1
ENSMUST00000113759.2
ENSMUST00000113755.1
ENSMUST00000137558.1
ENSMUST00000046571.7
Odf2







outer dense fiber of sperm tails 2







chr1_-_55088156 4.263 ENSMUST00000127861.1
ENSMUST00000144077.1
Hspd1

heat shock protein 1 (chaperonin)

chr4_+_150236685 4.222 ENSMUST00000150175.1
Eno1
enolase 1, alpha non-neuron
chr4_-_139832920 4.218 ENSMUST00000174681.1
Pax7
paired box gene 7
chr10_+_128092771 4.216 ENSMUST00000170054.2
ENSMUST00000045621.8
Baz2a

bromodomain adjacent to zinc finger domain, 2A

chr13_+_44729794 4.189 ENSMUST00000172830.1
Jarid2
jumonji, AT rich interactive domain 2
chr7_+_83631959 4.150 ENSMUST00000075418.7
ENSMUST00000117410.1
Stard5

StAR-related lipid transfer (START) domain containing 5

chr1_-_138847579 4.146 ENSMUST00000093486.3
ENSMUST00000046870.6
Lhx9

LIM homeobox protein 9

chr4_+_129287614 4.146 ENSMUST00000102599.3
Sync
syncoilin
chr5_-_137116177 4.118 ENSMUST00000054384.5
ENSMUST00000152207.1
Trim56

tripartite motif-containing 56

chr16_+_13358375 4.118 ENSMUST00000149359.1
Mkl2
MKL/myocardin-like 2
chr19_-_6057736 4.115 ENSMUST00000007482.6
Mrpl49
mitochondrial ribosomal protein L49
chr2_+_29889720 4.107 ENSMUST00000113767.1
Odf2
outer dense fiber of sperm tails 2
chr3_+_106113229 4.097 ENSMUST00000079132.5
ENSMUST00000139086.1
Chia

chitinase, acidic

chr16_-_56024628 4.061 ENSMUST00000119981.1
ENSMUST00000096021.3
Pcnp

PEST proteolytic signal containing nuclear protein

chr12_-_110696332 4.019 ENSMUST00000094361.4
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr19_+_6363719 4.009 ENSMUST00000113489.1
ENSMUST00000113488.1
Sf1

splicing factor 1

chr6_+_53573364 4.002 ENSMUST00000047450.7
Creb5
cAMP responsive element binding protein 5
chr11_+_100415697 3.981 ENSMUST00000001595.3
Fkbp10
FK506 binding protein 10
chr6_+_128438757 3.925 ENSMUST00000144745.1
Gm10069
predicted gene 10069
chr4_+_41903610 3.925 ENSMUST00000098128.3
Gm21541
predicted gene, 21541
chr4_+_42114817 3.865 ENSMUST00000098123.3
Gm13304
predicted gene 13304
chr18_-_84681966 3.863 ENSMUST00000168419.1
Cndp2
CNDP dipeptidase 2 (metallopeptidase M20 family)
chr6_+_82041623 3.796 ENSMUST00000042974.8
Eva1a
eva-1 homolog A (C. elegans)
chr18_-_31949571 3.785 ENSMUST00000064016.5
Gpr17
G protein-coupled receptor 17
chr3_-_108017806 3.780 ENSMUST00000126593.1
Gstm1
glutathione S-transferase, mu 1
chr11_-_115813621 3.744 ENSMUST00000041684.4
ENSMUST00000156812.1
Caskin2

CASK-interacting protein 2

chr5_+_135887905 3.710 ENSMUST00000005077.6
Hspb1
heat shock protein 1
chr11_+_114851814 3.709 ENSMUST00000053361.5
ENSMUST00000021071.7
ENSMUST00000136785.1
Gprc5c


G protein-coupled receptor, family C, group 5, member C


chr18_-_10706688 3.682 ENSMUST00000002549.7
ENSMUST00000117726.1
ENSMUST00000117828.1
Abhd3


abhydrolase domain containing 3


chr9_-_72111172 3.662 ENSMUST00000183992.1
Tcf12
transcription factor 12
chr9_+_40801235 3.661 ENSMUST00000117870.1
ENSMUST00000117557.1
Hspa8

heat shock protein 8

chr2_+_31759993 3.659 ENSMUST00000124089.1
Abl1
c-abl oncogene 1, non-receptor tyrosine kinase
chr7_+_92561141 3.648 ENSMUST00000032842.6
ENSMUST00000085017.4
Ccdc90b

coiled-coil domain containing 90B

chr7_-_140102384 3.637 ENSMUST00000120034.1
ENSMUST00000121115.1
ENSMUST00000026539.7
Fuom


fucose mutarotase


chr1_+_138963709 3.614 ENSMUST00000168527.1
Dennd1b
DENN/MADD domain containing 1B
chr7_+_139389072 3.606 ENSMUST00000106098.1
ENSMUST00000026550.7
Inpp5a

inositol polyphosphate-5-phosphatase A

chr11_+_53770458 3.604 ENSMUST00000138913.1
ENSMUST00000123376.1
ENSMUST00000019043.6
ENSMUST00000133291.1
Irf1



interferon regulatory factor 1




Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 22.7 GO:0046552 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552)
5.0 15.0 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
4.8 14.3 GO:0021759 globus pallidus development(GO:0021759)
4.0 20.1 GO:2000981 negative regulation of mechanoreceptor differentiation(GO:0045632) negative regulation of inner ear receptor cell differentiation(GO:2000981)
3.8 11.5 GO:0002842 T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
3.3 9.9 GO:0072076 nephrogenic mesenchyme development(GO:0072076)
3.1 9.3 GO:0030421 defecation(GO:0030421)
2.9 46.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
2.7 8.0 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
2.4 9.5 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
2.4 11.8 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
2.3 7.0 GO:0010757 negative regulation of plasminogen activation(GO:0010757)
2.2 8.9 GO:0002337 B-1a B cell differentiation(GO:0002337)
2.2 6.6 GO:0021698 cerebellar cortex structural organization(GO:0021698)
2.1 6.3 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
2.1 12.4 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
2.0 7.9 GO:0048631 regulation of skeletal muscle tissue growth(GO:0048631)
2.0 11.8 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
1.9 9.7 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
1.8 9.0 GO:0006348 chromatin silencing at telomere(GO:0006348)
1.8 5.4 GO:0045819 positive regulation of glycogen catabolic process(GO:0045819)
1.8 7.1 GO:0006529 asparagine biosynthetic process(GO:0006529)
1.7 12.2 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
1.7 5.0 GO:0003360 brainstem development(GO:0003360)
1.6 4.9 GO:1990046 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
1.6 6.4 GO:0045343 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
1.6 4.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
1.6 6.2 GO:2000313 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313)
1.4 10.1 GO:0032534 regulation of microvillus assembly(GO:0032534)
1.4 8.5 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
1.3 5.3 GO:0007056 spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282)
1.3 18.3 GO:0030238 male sex determination(GO:0030238)
1.3 6.5 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
1.3 5.1 GO:0042276 error-prone translesion synthesis(GO:0042276)
1.3 11.5 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
1.3 10.2 GO:0016081 synaptic vesicle docking(GO:0016081)
1.2 4.9 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
1.2 7.4 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
1.2 23.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
1.2 3.7 GO:1903054 lysosomal membrane organization(GO:0097212) negative regulation of extracellular matrix organization(GO:1903054) positive regulation of protein folding(GO:1903334)
1.2 6.1 GO:0060040 retinal bipolar neuron differentiation(GO:0060040)
1.2 2.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
1.2 4.8 GO:0060032 notochord regression(GO:0060032)
1.2 3.6 GO:2000564 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) CD8-positive, alpha-beta T cell proliferation(GO:0035740) negative regulation of regulatory T cell differentiation(GO:0045590) regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000564)
1.2 2.4 GO:0035860 glial cell-derived neurotrophic factor receptor signaling pathway(GO:0035860)
1.2 3.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
1.1 10.1 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
1.1 3.3 GO:0033566 gamma-tubulin complex localization(GO:0033566)
1.1 2.2 GO:0040009 regulation of growth rate(GO:0040009)
1.1 3.2 GO:0097461 ferric iron import(GO:0033216) ferric iron import into cell(GO:0097461)
1.1 3.2 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
1.0 6.3 GO:0002326 B cell lineage commitment(GO:0002326)
1.0 4.1 GO:0035262 gonad morphogenesis(GO:0035262)
1.0 9.3 GO:1902913 positive regulation of melanocyte differentiation(GO:0045636) positive regulation of neuroepithelial cell differentiation(GO:1902913)
1.0 3.1 GO:1904154 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
1.0 5.0 GO:0010668 ectodermal cell differentiation(GO:0010668)
1.0 6.9 GO:0007296 vitellogenesis(GO:0007296)
1.0 15.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.9 5.7 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.9 7.6 GO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway(GO:0007195)
0.9 6.6 GO:0032782 bile acid secretion(GO:0032782)
0.9 4.6 GO:0003420 regulation of growth plate cartilage chondrocyte proliferation(GO:0003420)
0.9 2.8 GO:0006597 spermine biosynthetic process(GO:0006597)
0.9 2.7 GO:0019043 establishment of viral latency(GO:0019043)
0.9 3.6 GO:0035743 CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745)
0.9 24.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.9 7.9 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.9 7.0 GO:0014807 regulation of somitogenesis(GO:0014807)
0.8 7.6 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.8 11.0 GO:0046643 regulation of gamma-delta T cell differentiation(GO:0045586) regulation of gamma-delta T cell activation(GO:0046643)
0.8 10.9 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.8 10.5 GO:0051451 myoblast migration(GO:0051451)
0.8 2.3 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.8 15.1 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.7 3.0 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.7 3.6 GO:0072488 nitrogen utilization(GO:0019740) ammonium transmembrane transport(GO:0072488)
0.7 8.6 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.7 13.6 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.7 3.5 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.7 3.5 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.7 8.2 GO:0015825 L-serine transport(GO:0015825)
0.7 2.1 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.7 11.6 GO:0005980 polysaccharide catabolic process(GO:0000272) glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.7 3.4 GO:0034421 post-translational protein acetylation(GO:0034421)
0.7 6.7 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.7 8.5 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.6 13.0 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.6 3.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.6 5.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.6 6.9 GO:1990173 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.6 1.3 GO:0032829 regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032829)
0.6 4.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.6 6.8 GO:0002176 male germ cell proliferation(GO:0002176)
0.6 4.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.6 2.4 GO:1901163 trophoblast cell migration(GO:0061450) regulation of trophoblast cell migration(GO:1901163) positive regulation of trophoblast cell migration(GO:1901165)
0.6 2.3 GO:0051043 regulation of membrane protein ectodomain proteolysis(GO:0051043)
0.6 3.5 GO:0009235 cobalamin metabolic process(GO:0009235)
0.6 7.3 GO:0018126 protein hydroxylation(GO:0018126)
0.6 2.2 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.5 2.2 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.5 2.2 GO:0007113 endomitotic cell cycle(GO:0007113)
0.5 6.6 GO:0070986 left/right axis specification(GO:0070986)
0.5 3.8 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.5 2.1 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.5 2.6 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.5 2.6 GO:2000587 regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000586) negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.5 2.5 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.5 1.5 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008) peptidyl-glycine modification(GO:0018201)
0.5 2.5 GO:0060018 astrocyte fate commitment(GO:0060018)
0.5 5.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.5 3.5 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.5 6.4 GO:0032287 peripheral nervous system myelin maintenance(GO:0032287)
0.5 1.4 GO:0003278 apoptotic process involved in heart morphogenesis(GO:0003278)
0.5 4.7 GO:0001522 pseudouridine synthesis(GO:0001522)
0.5 3.2 GO:0031053 primary miRNA processing(GO:0031053)
0.5 5.1 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.5 0.9 GO:0060333 macrophage fusion(GO:0034238) regulation of macrophage fusion(GO:0034239) interferon-gamma-mediated signaling pathway(GO:0060333)
0.5 3.6 GO:0006004 fucose metabolic process(GO:0006004)
0.4 1.8 GO:0060355 positive regulation of cell adhesion molecule production(GO:0060355)
0.4 8.4 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.4 3.1 GO:0042572 retinol metabolic process(GO:0042572)
0.4 7.0 GO:0051084 'de novo' protein folding(GO:0006458) 'de novo' posttranslational protein folding(GO:0051084)
0.4 9.1 GO:0046596 regulation of viral entry into host cell(GO:0046596)
0.4 9.4 GO:0031572 G2 DNA damage checkpoint(GO:0031572)
0.4 23.0 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.4 3.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.4 8.9 GO:0042474 middle ear morphogenesis(GO:0042474)
0.4 4.5 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.4 1.6 GO:0051294 establishment of mitotic spindle orientation(GO:0000132) establishment of mitotic spindle localization(GO:0040001) establishment of spindle orientation(GO:0051294)
0.4 3.2 GO:0048311 mitochondrion distribution(GO:0048311)
0.4 2.3 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.4 3.9 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.3 3.4 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.3 14.5 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.3 9.1 GO:0000154 rRNA modification(GO:0000154)
0.3 1.3 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.3 4.6 GO:0097062 dendritic spine maintenance(GO:0097062)
0.3 2.2 GO:0071285 cellular response to lithium ion(GO:0071285)
0.3 2.8 GO:0098535 de novo centriole assembly(GO:0098535)
0.3 0.9 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.3 3.6 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.3 1.8 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.3 5.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.3 3.8 GO:0035751 regulation of lysosomal lumen pH(GO:0035751)
0.3 2.9 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.3 4.3 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.3 1.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.3 4.3 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.3 1.4 GO:0097501 stress response to metal ion(GO:0097501)
0.3 1.4 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.3 2.7 GO:0046036 GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.3 1.3 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.3 7.8 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.2 1.7 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.2 1.0 GO:0031282 regulation of guanylate cyclase activity(GO:0031282)
0.2 3.6 GO:0046855 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.2 0.9 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.2 2.1 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.2 2.3 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.2 2.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 2.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.2 1.1 GO:1904338 regulation of dopaminergic neuron differentiation(GO:1904338)
0.2 8.0 GO:0006801 superoxide metabolic process(GO:0006801)
0.2 0.6 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.2 0.4 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.2 0.8 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2 0.6 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.2 1.8 GO:0021684 cerebellar granular layer morphogenesis(GO:0021683) cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.2 5.5 GO:0048246 macrophage chemotaxis(GO:0048246)
0.2 4.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 10.4 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.2 0.6 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.2 2.8 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.2 16.7 GO:0050772 positive regulation of axonogenesis(GO:0050772)
0.2 1.6 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.2 0.8 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098) response to amino acid starvation(GO:1990928)
0.2 1.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.2 2.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.2 0.8 GO:0019249 lactate biosynthetic process from pyruvate(GO:0019244) lactate biosynthetic process(GO:0019249)
0.2 3.0 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2 3.7 GO:0010842 retina layer formation(GO:0010842)
0.2 2.6 GO:0045116 protein neddylation(GO:0045116)
0.2 0.5 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.2 0.5 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 0.8 GO:1900364 negative regulation of mRNA polyadenylation(GO:1900364)
0.1 4.1 GO:0045103 intermediate filament-based process(GO:0045103)
0.1 1.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.1 2.1 GO:0017144 drug metabolic process(GO:0017144)
0.1 1.1 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.1 4.6 GO:0015909 long-chain fatty acid transport(GO:0015909)
0.1 0.9 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.1 2.8 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 2.9 GO:0006509 membrane protein ectodomain proteolysis(GO:0006509)
0.1 6.4 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.1 6.3 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.1 1.0 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 9.1 GO:0007601 visual perception(GO:0007601)
0.1 0.8 GO:0032790 ribosome disassembly(GO:0032790)
0.1 3.7 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.1 5.3 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 1.2 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.1 0.9 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 0.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 2.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.1 0.8 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 2.3 GO:0016180 snRNA processing(GO:0016180)
0.1 1.3 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.1 0.5 GO:1904707 traversing start control point of mitotic cell cycle(GO:0007089) positive regulation of vascular smooth muscle cell proliferation(GO:1904707)
0.1 0.4 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 2.0 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.1 2.2 GO:1901522 positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus(GO:1901522)
0.1 4.0 GO:0060612 adipose tissue development(GO:0060612)
0.1 0.6 GO:0015879 carnitine transport(GO:0015879)
0.1 2.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.3 GO:0043201 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.1 1.5 GO:0031018 endocrine pancreas development(GO:0031018)
0.1 4.1 GO:0048636 positive regulation of striated muscle tissue development(GO:0045844) positive regulation of muscle organ development(GO:0048636) positive regulation of muscle tissue development(GO:1901863)
0.1 1.1 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 4.7 GO:0006749 glutathione metabolic process(GO:0006749)
0.1 1.7 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.8 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.1 2.6 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.3 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.1 1.9 GO:0043029 T cell homeostasis(GO:0043029)
0.1 1.4 GO:0048247 lymphocyte chemotaxis(GO:0048247)
0.1 1.0 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.1 0.2 GO:0046077 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine ribonucleoside diphosphate metabolic process(GO:0009193) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) pyrimidine nucleobase biosynthetic process(GO:0019856) UDP metabolic process(GO:0046048) dUDP metabolic process(GO:0046077)
0.1 4.1 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.1 1.4 GO:0033146 regulation of intracellular estrogen receptor signaling pathway(GO:0033146)
0.1 0.7 GO:0006359 regulation of transcription from RNA polymerase III promoter(GO:0006359)
0.1 0.7 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.1 4.6 GO:0006513 protein monoubiquitination(GO:0006513)
0.1 0.6 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.1 2.7 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 7.0 GO:0060348 bone development(GO:0060348)
0.1 7.6 GO:0050658 nucleic acid transport(GO:0050657) RNA transport(GO:0050658)
0.1 3.7 GO:0007127 meiosis I(GO:0007127)
0.1 7.5 GO:0008360 regulation of cell shape(GO:0008360)
0.1 1.8 GO:0017145 stem cell division(GO:0017145)
0.1 0.3 GO:0019065 receptor-mediated endocytosis of virus by host cell(GO:0019065) endocytosis involved in viral entry into host cell(GO:0075509)
0.1 1.1 GO:0006220 pyrimidine nucleotide metabolic process(GO:0006220)
0.1 3.8 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.1 0.6 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 1.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.1 1.6 GO:0034605 cellular response to heat(GO:0034605)
0.1 11.8 GO:0007517 muscle organ development(GO:0007517)
0.1 4.6 GO:0050796 regulation of insulin secretion(GO:0050796)
0.1 0.5 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.1 0.5 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 1.3 GO:0030488 tRNA methylation(GO:0030488)
0.1 3.5 GO:0006413 translational initiation(GO:0006413)
0.0 1.2 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0034244 negative regulation of DNA-templated transcription, elongation(GO:0032785) negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 1.7 GO:1902653 cholesterol biosynthetic process(GO:0006695) secondary alcohol biosynthetic process(GO:1902653)
0.0 10.9 GO:0032259 methylation(GO:0032259)
0.0 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:0071492 cellular response to UV-A(GO:0071492)
0.0 1.5 GO:0009225 nucleotide-sugar metabolic process(GO:0009225)
0.0 5.3 GO:0007160 cell-matrix adhesion(GO:0007160)
0.0 2.7 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.4 GO:0015812 gamma-aminobutyric acid transport(GO:0015812)
0.0 3.1 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.4 GO:2000398 regulation of T cell differentiation in thymus(GO:0033081) regulation of thymocyte aggregation(GO:2000398)
0.0 1.3 GO:0001701 in utero embryonic development(GO:0001701)
0.0 0.3 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.0 1.2 GO:0006635 fatty acid beta-oxidation(GO:0006635)
0.0 0.4 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 1.2 GO:0051225 spindle assembly(GO:0051225)
0.0 0.6 GO:0048736 appendage development(GO:0048736) limb development(GO:0060173)
0.0 0.9 GO:0009411 response to UV(GO:0009411)
0.0 1.3 GO:0008033 tRNA processing(GO:0008033)
0.0 0.1 GO:0042182 ketone catabolic process(GO:0042182)
0.0 0.2 GO:0001816 cytokine production(GO:0001816)
0.0 0.7 GO:0022904 respiratory electron transport chain(GO:0022904)
0.0 0.5 GO:0051057 positive regulation of small GTPase mediated signal transduction(GO:0051057)
0.0 0.8 GO:0016197 endosomal transport(GO:0016197)
0.0 3.4 GO:0016055 Wnt signaling pathway(GO:0016055) cell-cell signaling by wnt(GO:0198738)
0.0 0.8 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)
0.0 0.3 GO:0048286 lung alveolus development(GO:0048286)
0.0 0.0 GO:0048799 ureter maturation(GO:0035799) organ maturation(GO:0048799)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 12.2 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
2.9 2.9 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
2.4 11.8 GO:0097226 sperm mitochondrial sheath(GO:0097226)
2.1 6.4 GO:0097512 cardiac myofibril(GO:0097512)
1.9 11.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.8 5.3 GO:0042585 germinal vesicle(GO:0042585)
1.7 10.1 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
1.7 5.0 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
1.6 13.1 GO:0005818 aster(GO:0005818)
1.6 4.7 GO:0005588 collagen type V trimer(GO:0005588)
1.6 7.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
1.5 7.6 GO:0031523 Myb complex(GO:0031523)
1.3 10.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
1.2 5.8 GO:0030314 junctional membrane complex(GO:0030314)
1.1 5.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
1.0 13.3 GO:0030061 mitochondrial crista(GO:0030061)
0.9 9.4 GO:0070531 BRCA1-A complex(GO:0070531)
0.9 3.7 GO:0043202 lysosomal lumen(GO:0043202)
0.9 9.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.9 2.7 GO:0030905 retromer, tubulation complex(GO:0030905)
0.9 7.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.9 2.7 GO:0097524 sperm plasma membrane(GO:0097524)
0.9 3.4 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.8 4.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.7 10.7 GO:0045180 basal cortex(GO:0045180)
0.6 3.2 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.6 7.0 GO:0031091 platelet alpha granule(GO:0031091) extrinsic component of external side of plasma membrane(GO:0031232)
0.6 6.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.6 3.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.6 1.8 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.6 8.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.5 4.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.5 5.4 GO:0000243 commitment complex(GO:0000243)
0.5 24.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.5 3.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.5 5.0 GO:0031595 nuclear proteasome complex(GO:0031595)
0.5 1.4 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.5 6.0 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 2.2 GO:0032389 MutLalpha complex(GO:0032389)
0.4 2.9 GO:0097422 tubular endosome(GO:0097422)
0.4 1.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.4 1.5 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.4 6.4 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.4 5.6 GO:0005640 nuclear outer membrane(GO:0005640)
0.3 2.8 GO:0098536 deuterosome(GO:0098536)
0.3 2.7 GO:0060091 kinocilium(GO:0060091)
0.3 4.9 GO:0042101 T cell receptor complex(GO:0042101)
0.3 21.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.3 4.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.3 2.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.3 2.4 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.3 16.4 GO:0016459 myosin complex(GO:0016459)
0.3 6.7 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 1.7 GO:0005677 chromatin silencing complex(GO:0005677)
0.3 1.6 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.3 3.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.3 2.4 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.3 2.9 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.2 11.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.2 6.6 GO:0051233 spindle midzone(GO:0051233)
0.2 4.3 GO:0032839 dendrite cytoplasm(GO:0032839)
0.2 18.1 GO:0005604 basement membrane(GO:0005604)
0.2 9.2 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.2 2.2 GO:0044232 organelle membrane contact site(GO:0044232)
0.2 11.8 GO:0031985 Golgi cisterna(GO:0031985)
0.2 6.0 GO:0000788 nuclear nucleosome(GO:0000788)
0.2 0.8 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.2 1.2 GO:0030891 VCB complex(GO:0030891)
0.2 2.3 GO:0032039 integrator complex(GO:0032039)
0.2 3.9 GO:0002102 podosome(GO:0002102)
0.2 5.1 GO:0005811 lipid particle(GO:0005811)
0.2 12.1 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.1 8.7 GO:0005882 intermediate filament(GO:0005882)
0.1 12.7 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.1 3.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 1.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 10.2 GO:0030315 T-tubule(GO:0030315)
0.1 1.7 GO:0008385 IkappaB kinase complex(GO:0008385)
0.1 3.0 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 1.2 GO:0042588 zymogen granule(GO:0042588)
0.1 4.4 GO:0030667 secretory granule membrane(GO:0030667)
0.1 2.2 GO:0019897 extrinsic component of plasma membrane(GO:0019897)
0.1 1.2 GO:0045298 tubulin complex(GO:0045298)
0.1 2.7 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.1 6.8 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 1.7 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 4.0 GO:0044295 axonal growth cone(GO:0044295)
0.1 2.0 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 5.7 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.1 4.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 14.9 GO:0005802 trans-Golgi network(GO:0005802)
0.1 1.3 GO:0071203 WASH complex(GO:0071203)
0.1 4.2 GO:0005720 nuclear heterochromatin(GO:0005720)
0.1 2.9 GO:0005719 nuclear euchromatin(GO:0005719)
0.1 9.4 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.4 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.1 10.1 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.1 8.5 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 2.3 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 9.7 GO:0016324 apical plasma membrane(GO:0016324)
0.1 1.6 GO:0031672 A band(GO:0031672)
0.1 1.6 GO:0045177 apical part of cell(GO:0045177)
0.1 1.1 GO:0001741 XY body(GO:0001741)
0.1 3.7 GO:0005643 nuclear pore(GO:0005643)
0.1 1.7 GO:0043189 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.7 GO:0030175 filopodium(GO:0030175)
0.1 10.5 GO:0031965 nuclear membrane(GO:0031965)
0.1 5.7 GO:0016607 nuclear speck(GO:0016607)
0.1 3.2 GO:0031526 brush border membrane(GO:0031526)
0.1 1.2 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.1 2.2 GO:0045171 intercellular bridge(GO:0045171)
0.1 1.0 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 2.4 GO:0043209 myelin sheath(GO:0043209)
0.0 0.5 GO:0031011 Ino80 complex(GO:0031011)
0.0 12.2 GO:0005667 transcription factor complex(GO:0005667)
0.0 2.6 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 1.5 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 5.7 GO:0005681 spliceosomal complex(GO:0005681)
0.0 18.2 GO:0009986 cell surface(GO:0009986)
0.0 0.5 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 1.5 GO:0043197 dendritic spine(GO:0043197)
0.0 0.9 GO:0015934 large ribosomal subunit(GO:0015934) cytosolic large ribosomal subunit(GO:0022625)
0.0 2.3 GO:0000502 proteasome complex(GO:0000502)
0.0 0.6 GO:0005746 mitochondrial respiratory chain(GO:0005746)
0.0 1.2 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 0.3 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0032420 stereocilium(GO:0032420)
0.0 6.9 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.0 0.9 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 36.9 GO:0005739 mitochondrion(GO:0005739)
0.0 0.3 GO:0055037 recycling endosome(GO:0055037)
0.0 1.2 GO:0000793 condensed chromosome(GO:0000793)
0.0 0.1 GO:0030904 retromer complex(GO:0030904)
0.0 51.1 GO:0005634 nucleus(GO:0005634)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
4.6 13.9 GO:0005118 sevenless binding(GO:0005118)
3.2 9.7 GO:0005534 galactose binding(GO:0005534)
2.9 11.6 GO:2001069 glycogen binding(GO:2001069)
2.9 11.5 GO:0045131 pre-mRNA branch point binding(GO:0045131)
2.6 13.1 GO:0061676 importin-alpha family protein binding(GO:0061676)
2.4 14.4 GO:0002135 CTP binding(GO:0002135)
2.3 9.2 GO:0016018 cyclosporin A binding(GO:0016018)
2.1 46.3 GO:0070410 co-SMAD binding(GO:0070410)
2.0 8.0 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
1.9 9.5 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
1.9 7.6 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
1.9 15.0 GO:0031432 titin binding(GO:0031432)
1.9 3.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
1.8 5.4 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
1.8 7.1 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
1.7 8.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
1.6 11.5 GO:0043559 insulin binding(GO:0043559)
1.6 4.9 GO:1901611 phosphatidylglycerol binding(GO:1901611) cardiolipin binding(GO:1901612)
1.6 6.4 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
1.6 6.4 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
1.5 7.7 GO:0032767 copper-dependent protein binding(GO:0032767)
1.5 12.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
1.5 5.9 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
1.4 4.2 GO:0032052 bile acid binding(GO:0032052)
1.4 4.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
1.3 10.1 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
1.2 3.7 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
1.2 3.7 GO:0031686 A1 adenosine receptor binding(GO:0031686)
1.2 14.3 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
1.1 5.7 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095)
1.1 3.2 GO:0008823 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
1.1 3.2 GO:0004828 serine-tRNA ligase activity(GO:0004828)
1.0 6.3 GO:0070644 vitamin D response element binding(GO:0070644)
1.0 15.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.9 10.1 GO:0034943 acyl-CoA ligase activity(GO:0003996) 3-oxo-2-(2'-pentenyl)cyclopentane-1-octanoic acid CoA ligase activity(GO:0010435) 3-isopropenyl-6-oxoheptanoyl-CoA synthetase activity(GO:0018854) 2-oxo-delta3-4,5,5-trimethylcyclopentenylacetyl-CoA synthetase activity(GO:0018855) benzoyl acetate-CoA ligase activity(GO:0018856) 2,4-dichlorobenzoate-CoA ligase activity(GO:0018857) pivalate-CoA ligase activity(GO:0034783) cyclopropanecarboxylate-CoA ligase activity(GO:0034793) adipate-CoA ligase activity(GO:0034796) citronellyl-CoA ligase activity(GO:0034823) mentha-1,3-dione-CoA ligase activity(GO:0034841) thiophene-2-carboxylate-CoA ligase activity(GO:0034842) 2,4,4-trimethylpentanoate-CoA ligase activity(GO:0034865) cis-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034942) trans-2-methyl-5-isopropylhexa-2,5-dienoate-CoA ligase activity(GO:0034943) branched-chain acyl-CoA synthetase (ADP-forming) activity(GO:0043759) aryl-CoA synthetase (ADP-forming) activity(GO:0043762) 3-hydroxypropionyl-CoA synthetase activity(GO:0043955) perillic acid:CoA ligase (ADP-forming) activity(GO:0052685) perillic acid:CoA ligase (AMP-forming) activity(GO:0052686) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (ADP-forming) activity(GO:0052687) (3R)-3-isopropenyl-6-oxoheptanoate:CoA ligase (AMP-forming) activity(GO:0052688) pristanate-CoA ligase activity(GO:0070251) malonyl-CoA synthetase activity(GO:0090409)
0.9 9.2 GO:0042301 phosphate ion binding(GO:0042301)
0.9 3.6 GO:0042806 fucose binding(GO:0042806)
0.9 3.6 GO:0042731 PH domain binding(GO:0042731)
0.9 6.3 GO:0043237 laminin-1 binding(GO:0043237)
0.9 11.3 GO:0008301 DNA binding, bending(GO:0008301)
0.9 2.6 GO:0015038 glutathione disulfide oxidoreductase activity(GO:0015038) protein-disulfide reductase (glutathione) activity(GO:0019153)
0.8 5.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.8 3.4 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.8 2.5 GO:0005110 frizzled-2 binding(GO:0005110)
0.8 12.5 GO:0051018 protein kinase A binding(GO:0051018)
0.8 5.0 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.8 4.1 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.8 13.0 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.8 7.0 GO:0005212 structural constituent of eye lens(GO:0005212)
0.8 5.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.8 9.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.7 10.4 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.7 7.4 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.7 17.0 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.7 11.8 GO:0008307 structural constituent of muscle(GO:0008307)
0.7 5.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.7 7.9 GO:0030957 Tat protein binding(GO:0030957)
0.7 5.0 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.7 4.9 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.7 15.9 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.7 2.1 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.7 8.0 GO:0070097 delta-catenin binding(GO:0070097)
0.7 2.7 GO:1990460 leptin receptor binding(GO:1990460)
0.7 6.6 GO:0001055 RNA polymerase II activity(GO:0001055)
0.6 17.4 GO:0071837 HMG box domain binding(GO:0071837)
0.6 3.2 GO:0001069 regulatory region RNA binding(GO:0001069)
0.6 6.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.6 4.6 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.6 3.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.5 2.2 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.5 24.7 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.5 3.2 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.5 9.0 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.5 9.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.5 11.5 GO:0001784 phosphotyrosine binding(GO:0001784)
0.5 4.7 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.5 3.5 GO:0031419 cobalamin binding(GO:0031419)
0.5 1.5 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379)
0.5 3.0 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.5 8.1 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.5 3.3 GO:0034452 dynactin binding(GO:0034452)
0.5 4.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.5 1.4 GO:0047066 phospholipid-hydroperoxide glutathione peroxidase activity(GO:0047066)
0.5 1.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.5 2.8 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.5 3.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.4 3.5 GO:0001972 retinoic acid binding(GO:0001972)
0.4 1.8 GO:0003941 L-serine ammonia-lyase activity(GO:0003941)
0.4 2.2 GO:0051880 Y-form DNA binding(GO:0000403) bubble DNA binding(GO:0000405) G-quadruplex DNA binding(GO:0051880)
0.4 4.7 GO:0016151 nickel cation binding(GO:0016151)
0.4 2.1 GO:0008392 arachidonic acid monooxygenase activity(GO:0008391) arachidonic acid epoxygenase activity(GO:0008392)
0.4 2.9 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.4 4.9 GO:0034946 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466)
0.4 4.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4 5.1 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.4 2.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.4 2.6 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.4 10.8 GO:0005109 frizzled binding(GO:0005109)
0.4 1.4 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.4 4.2 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013) RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.3 12.8 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.3 1.7 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.3 5.7 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.3 1.0 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.3 1.6 GO:0034511 U3 snoRNA binding(GO:0034511)
0.3 1.9 GO:1990932 5.8S rRNA binding(GO:1990932)
0.3 9.3 GO:0005112 Notch binding(GO:0005112)
0.3 4.1 GO:0019215 intermediate filament binding(GO:0019215)
0.3 1.6 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.3 2.7 GO:0000182 rDNA binding(GO:0000182)
0.3 6.4 GO:0030291 protein serine/threonine kinase inhibitor activity(GO:0030291)
0.3 10.9 GO:0070888 E-box binding(GO:0070888)
0.3 1.5 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.3 1.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.3 9.0 GO:0017147 Wnt-protein binding(GO:0017147)
0.3 3.9 GO:0016805 dipeptidase activity(GO:0016805)
0.3 7.6 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.3 11.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 11.5 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.2 2.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.2 0.9 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.2 3.4 GO:0005355 glucose transmembrane transporter activity(GO:0005355)
0.2 3.4 GO:0000400 four-way junction DNA binding(GO:0000400)
0.2 3.6 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.2 7.3 GO:0032452 histone demethylase activity(GO:0032452)
0.2 2.3 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.2 3.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.2 1.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.2 6.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.2 0.8 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.2 0.6 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.2 2.4 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.2 1.8 GO:0008329 signaling pattern recognition receptor activity(GO:0008329) pattern recognition receptor activity(GO:0038187)
0.2 0.6 GO:0005124 scavenger receptor binding(GO:0005124)
0.2 2.9 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.2 0.6 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.2 4.2 GO:0003746 translation elongation factor activity(GO:0003746)
0.2 0.9 GO:0035184 histone threonine kinase activity(GO:0035184)
0.2 5.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 6.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.2 3.7 GO:0032794 GTPase activating protein binding(GO:0032794)
0.2 1.0 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.2 1.3 GO:0046790 virion binding(GO:0046790)
0.2 3.5 GO:0017049 GTP-Rho binding(GO:0017049)
0.2 10.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 1.7 GO:0016208 AMP binding(GO:0016208)
0.2 2.2 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.2 5.4 GO:0017069 snRNA binding(GO:0017069)
0.2 0.5 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.2 40.6 GO:0001077 transcriptional activator activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001077)
0.1 2.6 GO:0003924 GTPase activity(GO:0003924)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 3.9 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 2.2 GO:0015026 coreceptor activity(GO:0015026)
0.1 0.4 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.1 9.1 GO:0008083 growth factor activity(GO:0008083)
0.1 2.4 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.1 7.6 GO:0019955 cytokine binding(GO:0019955)
0.1 1.9 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.1 0.9 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 10.1 GO:0005125 cytokine activity(GO:0005125)
0.1 3.1 GO:0070717 poly-purine tract binding(GO:0070717)
0.1 0.4 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.5 GO:0001639 PLC activating G-protein coupled glutamate receptor activity(GO:0001639)
0.1 6.7 GO:0008186 ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.1 0.9 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.1 2.3 GO:0032183 SUMO binding(GO:0032183)
0.1 1.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.5 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.1 1.2 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 2.5 GO:0005504 fatty acid binding(GO:0005504)
0.1 14.7 GO:0051015 actin filament binding(GO:0051015)
0.1 2.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 1.2 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 1.7 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 13.0 GO:0008237 metallopeptidase activity(GO:0008237)
0.1 12.8 GO:0017137 Rab GTPase binding(GO:0017137)
0.1 8.6 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.1 1.8 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.1 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 2.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.1 0.2 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041)
0.1 0.8 GO:0070182 DNA polymerase binding(GO:0070182)
0.1 14.2 GO:0008757 S-adenosylmethionine-dependent methyltransferase activity(GO:0008757)
0.1 2.3 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 2.7 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812)
0.1 2.1 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.1 7.0 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.1 1.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.5 GO:0008097 5S rRNA binding(GO:0008097)
0.1 3.4 GO:0031593 polyubiquitin binding(GO:0031593)
0.1 1.8 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.1 13.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.1 GO:0005154 epidermal growth factor receptor binding(GO:0005154)
0.1 1.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 0.2 GO:0001224 RNA polymerase II transcription cofactor binding(GO:0001224) RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 1.0 GO:0003785 actin monomer binding(GO:0003785)
0.1 1.5 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.5 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.3 GO:0019107 myristoyltransferase activity(GO:0019107)
0.0 0.9 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
0.0 1.7 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.0 2.0 GO:0003697 single-stranded DNA binding(GO:0003697)
0.0 1.6 GO:0005179 hormone activity(GO:0005179)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 3.2 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 1.5 GO:0016836 hydro-lyase activity(GO:0016836)
0.0 2.7 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.4 GO:0050253 prenylcysteine methylesterase activity(GO:0010296) 1-oxa-2-oxocycloheptane lactonase activity(GO:0018731) sulfolactone hydrolase activity(GO:0018732) butyrolactone hydrolase activity(GO:0018734) endosulfan lactone lactonase activity(GO:0034892) L-ascorbate 6-phosphate lactonase activity(GO:0035460) Ser-tRNA(Thr) hydrolase activity(GO:0043905) Ala-tRNA(Pro) hydrolase activity(GO:0043906) Cys-tRNA(Pro) hydrolase activity(GO:0043907) Ser(Gly)-tRNA(Ala) hydrolase activity(GO:0043908) all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity(GO:0047376) retinyl-palmitate esterase activity(GO:0050253) mannosyl-oligosaccharide 1,6-alpha-mannosidase activity(GO:0052767) mannosyl-oligosaccharide 1,3-alpha-mannosidase activity(GO:0052768) methyl indole-3-acetate esterase activity(GO:0080030) methyl salicylate esterase activity(GO:0080031) methyl jasmonate esterase activity(GO:0080032)
0.0 0.1 GO:0071633 dihydroceramidase activity(GO:0071633)
0.0 1.8 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.3 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 1.2 GO:0003713 transcription coactivator activity(GO:0003713)
0.0 1.3 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 2.1 GO:0019783 ubiquitin-like protein-specific protease activity(GO:0019783)
0.0 0.9 GO:0003725 double-stranded RNA binding(GO:0003725)
0.0 0.6 GO:0005518 collagen binding(GO:0005518)
0.0 0.5 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.0 0.2 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841) lysophosphatidic acid acyltransferase activity(GO:0042171)