Motif ID: Hsf4
Z-value: 0.768
Transcription factors associated with Hsf4:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Hsf4 | ENSMUSG00000033249.4 | Hsf4 |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 4.5 | GO:1900041 | negative regulation of interleukin-2 secretion(GO:1900041) |
| 1.2 | 7.3 | GO:0045583 | regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585) |
| 0.8 | 2.4 | GO:0021529 | spinal cord oligodendrocyte cell differentiation(GO:0021529) spinal cord oligodendrocyte cell fate specification(GO:0021530) |
| 0.8 | 2.3 | GO:0010757 | negative regulation of plasminogen activation(GO:0010757) |
| 0.5 | 2.6 | GO:1901164 | negative regulation of trophoblast cell migration(GO:1901164) |
| 0.5 | 2.0 | GO:0035063 | nuclear speck organization(GO:0035063) |
| 0.5 | 2.0 | GO:0007056 | spindle assembly involved in female meiosis(GO:0007056) positive regulation of oocyte development(GO:0060282) |
| 0.5 | 1.4 | GO:0002842 | T cell mediated immune response to tumor cell(GO:0002424) regulation of T cell mediated immune response to tumor cell(GO:0002840) positive regulation of T cell mediated immune response to tumor cell(GO:0002842) |
| 0.5 | 0.5 | GO:0035799 | ureter maturation(GO:0035799) |
| 0.4 | 1.3 | GO:0019043 | establishment of viral latency(GO:0019043) |
| 0.4 | 1.7 | GO:0030576 | Cajal body organization(GO:0030576) |
| 0.4 | 2.1 | GO:1905049 | negative regulation of metalloendopeptidase activity(GO:1904684) negative regulation of metallopeptidase activity(GO:1905049) |
| 0.4 | 1.2 | GO:0010248 | B cell negative selection(GO:0002352) establishment or maintenance of transmembrane electrochemical gradient(GO:0010248) |
| 0.3 | 1.3 | GO:0033580 | protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125) |
| 0.3 | 1.3 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.3 | 1.3 | GO:0097211 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
| 0.3 | 4.1 | GO:0061299 | retina vasculature morphogenesis in camera-type eye(GO:0061299) |
| 0.3 | 0.9 | GO:1904154 | protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154) |
| 0.3 | 1.5 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.3 | 2.7 | GO:0032876 | negative regulation of DNA endoreduplication(GO:0032876) |
| 0.3 | 1.1 | GO:0046552 | eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) |
| 0.3 | 0.8 | GO:0002295 | T-helper cell lineage commitment(GO:0002295) interleukin-4-mediated signaling pathway(GO:0035771) |
| 0.3 | 1.3 | GO:0002457 | T cell antigen processing and presentation(GO:0002457) |
| 0.2 | 0.7 | GO:0008228 | opsonization(GO:0008228) |
| 0.2 | 3.9 | GO:0070986 | left/right axis specification(GO:0070986) |
| 0.2 | 0.7 | GO:1903054 | lysosomal membrane organization(GO:0097212) negative regulation of extracellular matrix organization(GO:1903054) positive regulation of protein folding(GO:1903334) |
| 0.2 | 1.0 | GO:1901252 | regulation of intracellular transport of viral material(GO:1901252) |
| 0.2 | 0.7 | GO:0048698 | negative regulation of collateral sprouting in absence of injury(GO:0048698) |
| 0.2 | 1.3 | GO:0003433 | chondrocyte development involved in endochondral bone morphogenesis(GO:0003433) |
| 0.2 | 0.6 | GO:0033566 | gamma-tubulin complex localization(GO:0033566) |
| 0.2 | 1.7 | GO:0006729 | tetrahydrobiopterin biosynthetic process(GO:0006729) tetrahydrobiopterin metabolic process(GO:0046146) |
| 0.2 | 1.2 | GO:0000056 | ribosomal small subunit export from nucleus(GO:0000056) |
| 0.2 | 0.6 | GO:0042228 | interleukin-8 biosynthetic process(GO:0042228) |
| 0.2 | 1.5 | GO:0006590 | thyroid hormone generation(GO:0006590) |
| 0.2 | 1.3 | GO:0006307 | DNA dealkylation involved in DNA repair(GO:0006307) |
| 0.2 | 1.1 | GO:0046602 | regulation of mitotic centrosome separation(GO:0046602) |
| 0.2 | 1.1 | GO:0002326 | B cell lineage commitment(GO:0002326) |
| 0.2 | 1.0 | GO:0002553 | histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553) |
| 0.2 | 0.5 | GO:0009174 | UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049) |
| 0.2 | 0.6 | GO:0032627 | interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667) |
| 0.2 | 6.2 | GO:0002474 | antigen processing and presentation of peptide antigen via MHC class I(GO:0002474) |
| 0.2 | 0.6 | GO:1902268 | negative regulation of polyamine transmembrane transport(GO:1902268) |
| 0.2 | 0.6 | GO:1901165 | positive regulation of trophoblast cell migration(GO:1901165) |
| 0.1 | 1.6 | GO:0034498 | early endosome to Golgi transport(GO:0034498) |
| 0.1 | 0.4 | GO:1902524 | negative regulation of interferon-alpha production(GO:0032687) interferon-alpha biosynthetic process(GO:0045349) regulation of interferon-alpha biosynthetic process(GO:0045354) negative regulation of interferon-beta biosynthetic process(GO:0045358) positive regulation of protein K48-linked ubiquitination(GO:1902524) |
| 0.1 | 0.3 | GO:0060838 | lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849) |
| 0.1 | 0.7 | GO:0016266 | O-glycan processing(GO:0016266) |
| 0.1 | 0.4 | GO:0097527 | necroptotic signaling pathway(GO:0097527) |
| 0.1 | 1.0 | GO:0017196 | N-terminal peptidyl-methionine acetylation(GO:0017196) |
| 0.1 | 1.3 | GO:0090037 | positive regulation of protein kinase C signaling(GO:0090037) |
| 0.1 | 0.8 | GO:0090383 | phagosome acidification(GO:0090383) |
| 0.1 | 0.7 | GO:0090666 | scaRNA localization to Cajal body(GO:0090666) |
| 0.1 | 0.5 | GO:0015888 | thiamine transport(GO:0015888) |
| 0.1 | 1.2 | GO:0009404 | toxin metabolic process(GO:0009404) |
| 0.1 | 1.6 | GO:0090051 | negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051) |
| 0.1 | 0.4 | GO:0033364 | mast cell secretory granule organization(GO:0033364) |
| 0.1 | 1.0 | GO:0032264 | IMP salvage(GO:0032264) |
| 0.1 | 2.3 | GO:0030213 | hyaluronan biosynthetic process(GO:0030213) |
| 0.1 | 0.6 | GO:0006564 | L-serine biosynthetic process(GO:0006564) |
| 0.1 | 1.5 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
| 0.1 | 0.7 | GO:0060903 | positive regulation of meiosis I(GO:0060903) |
| 0.1 | 0.4 | GO:0071492 | cellular response to UV-A(GO:0071492) |
| 0.1 | 0.4 | GO:0072061 | inner medullary collecting duct development(GO:0072061) |
| 0.1 | 0.4 | GO:0009414 | response to water deprivation(GO:0009414) |
| 0.1 | 0.6 | GO:0030240 | skeletal muscle thin filament assembly(GO:0030240) |
| 0.1 | 0.3 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.1 | 0.9 | GO:0031053 | primary miRNA processing(GO:0031053) |
| 0.1 | 0.5 | GO:0051012 | microtubule sliding(GO:0051012) |
| 0.1 | 1.0 | GO:0070389 | chaperone cofactor-dependent protein refolding(GO:0070389) |
| 0.1 | 0.3 | GO:0045409 | negative regulation of interleukin-6 biosynthetic process(GO:0045409) |
| 0.1 | 1.2 | GO:1904262 | negative regulation of TORC1 signaling(GO:1904262) |
| 0.1 | 0.8 | GO:1990173 | protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173) |
| 0.1 | 1.0 | GO:0030238 | male sex determination(GO:0030238) |
| 0.1 | 0.9 | GO:0046036 | GTP biosynthetic process(GO:0006183) CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036) |
| 0.1 | 0.3 | GO:0000720 | pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) |
| 0.1 | 0.5 | GO:0006348 | chromatin silencing at telomere(GO:0006348) |
| 0.1 | 0.8 | GO:0071318 | cellular response to ATP(GO:0071318) |
| 0.1 | 0.7 | GO:0006398 | mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398) |
| 0.1 | 0.7 | GO:0045779 | negative regulation of bone resorption(GO:0045779) |
| 0.1 | 1.1 | GO:0031017 | exocrine pancreas development(GO:0031017) |
| 0.1 | 0.3 | GO:0060455 | negative regulation of gastric acid secretion(GO:0060455) positive regulation of somatostatin secretion(GO:0090274) |
| 0.1 | 0.3 | GO:0001732 | formation of cytoplasmic translation initiation complex(GO:0001732) |
| 0.1 | 0.3 | GO:0042535 | positive regulation of tumor necrosis factor biosynthetic process(GO:0042535) |
| 0.1 | 0.6 | GO:0030299 | intestinal cholesterol absorption(GO:0030299) |
| 0.1 | 0.3 | GO:0019695 | choline metabolic process(GO:0019695) |
| 0.1 | 2.1 | GO:0015985 | energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) |
| 0.1 | 1.0 | GO:0050860 | negative regulation of T cell receptor signaling pathway(GO:0050860) |
| 0.1 | 0.2 | GO:0031117 | serotonin receptor signaling pathway(GO:0007210) positive regulation of microtubule depolymerization(GO:0031117) |
| 0.1 | 0.4 | GO:0045541 | negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206) |
| 0.1 | 0.4 | GO:0007021 | tubulin complex assembly(GO:0007021) |
| 0.1 | 1.3 | GO:0034453 | microtubule anchoring(GO:0034453) |
| 0.1 | 1.2 | GO:0051894 | positive regulation of focal adhesion assembly(GO:0051894) |
| 0.1 | 0.6 | GO:0030575 | nuclear body organization(GO:0030575) |
| 0.1 | 1.2 | GO:0031115 | negative regulation of microtubule polymerization(GO:0031115) |
| 0.1 | 0.2 | GO:0060836 | lymphatic endothelial cell differentiation(GO:0060836) |
| 0.1 | 0.7 | GO:0031936 | negative regulation of chromatin silencing(GO:0031936) |
| 0.1 | 0.3 | GO:0043654 | recognition of apoptotic cell(GO:0043654) |
| 0.1 | 0.2 | GO:0015793 | glycerol transport(GO:0015793) |
| 0.1 | 0.5 | GO:0042136 | neurotransmitter biosynthetic process(GO:0042136) |
| 0.1 | 1.9 | GO:0021591 | ventricular system development(GO:0021591) |
| 0.1 | 1.0 | GO:0001539 | cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285) axonemal dynein complex assembly(GO:0070286) |
| 0.1 | 1.8 | GO:0046470 | phosphatidylcholine metabolic process(GO:0046470) |
| 0.1 | 0.3 | GO:0038018 | Wnt receptor catabolic process(GO:0038018) |
| 0.1 | 0.4 | GO:0019348 | dolichol metabolic process(GO:0019348) |
| 0.1 | 0.5 | GO:2000270 | negative regulation of fibroblast apoptotic process(GO:2000270) |
| 0.1 | 0.3 | GO:0048254 | snoRNA localization(GO:0048254) |
| 0.1 | 0.7 | GO:0034244 | negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244) |
| 0.1 | 0.7 | GO:0060052 | neurofilament cytoskeleton organization(GO:0060052) |
| 0.0 | 1.0 | GO:0051044 | positive regulation of membrane protein ectodomain proteolysis(GO:0051044) |
| 0.0 | 0.2 | GO:0042364 | water-soluble vitamin biosynthetic process(GO:0042364) positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316) |
| 0.0 | 1.0 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
| 0.0 | 0.7 | GO:0010592 | positive regulation of lamellipodium assembly(GO:0010592) |
| 0.0 | 2.2 | GO:0071277 | cellular response to calcium ion(GO:0071277) |
| 0.0 | 0.1 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
| 0.0 | 0.3 | GO:0042359 | vitamin D metabolic process(GO:0042359) |
| 0.0 | 0.7 | GO:0035493 | SNARE complex assembly(GO:0035493) |
| 0.0 | 1.1 | GO:0045494 | photoreceptor cell maintenance(GO:0045494) |
| 0.0 | 1.7 | GO:0015914 | phospholipid transport(GO:0015914) |
| 0.0 | 0.9 | GO:0006471 | protein ADP-ribosylation(GO:0006471) |
| 0.0 | 0.5 | GO:1990403 | embryonic brain development(GO:1990403) |
| 0.0 | 0.4 | GO:0036376 | sodium ion export from cell(GO:0036376) |
| 0.0 | 0.2 | GO:0042769 | DNA damage response, detection of DNA damage(GO:0042769) |
| 0.0 | 0.2 | GO:0015862 | uridine transport(GO:0015862) |
| 0.0 | 0.2 | GO:0051036 | regulation of endosome size(GO:0051036) receptor internalization involved in canonical Wnt signaling pathway(GO:2000286) |
| 0.0 | 1.1 | GO:0032611 | interleukin-1 beta production(GO:0032611) |
| 0.0 | 0.2 | GO:0071360 | cellular response to exogenous dsRNA(GO:0071360) |
| 0.0 | 0.4 | GO:0032516 | positive regulation of phosphoprotein phosphatase activity(GO:0032516) |
| 0.0 | 1.5 | GO:0006687 | glycosphingolipid metabolic process(GO:0006687) |
| 0.0 | 0.5 | GO:0007097 | nuclear migration(GO:0007097) |
| 0.0 | 0.4 | GO:0042407 | cristae formation(GO:0042407) |
| 0.0 | 0.9 | GO:0045739 | positive regulation of DNA repair(GO:0045739) |
| 0.0 | 1.0 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 0.0 | 1.0 | GO:0000266 | mitochondrial fission(GO:0000266) |
| 0.0 | 0.1 | GO:0032918 | polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918) |
| 0.0 | 0.9 | GO:0031114 | regulation of microtubule depolymerization(GO:0031114) |
| 0.0 | 0.1 | GO:1904749 | regulation of protein localization to nucleolus(GO:1904749) positive regulation of protein localization to nucleolus(GO:1904751) |
| 0.0 | 0.6 | GO:0015909 | long-chain fatty acid transport(GO:0015909) |
| 0.0 | 0.6 | GO:0006220 | pyrimidine nucleotide metabolic process(GO:0006220) |
| 0.0 | 0.4 | GO:0071539 | protein localization to centrosome(GO:0071539) |
| 0.0 | 0.3 | GO:0007602 | phototransduction(GO:0007602) |
| 0.0 | 0.1 | GO:0014866 | skeletal myofibril assembly(GO:0014866) |
| 0.0 | 0.4 | GO:0043968 | histone H2A acetylation(GO:0043968) |
| 0.0 | 0.1 | GO:0097460 | positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) |
| 0.0 | 0.1 | GO:0000098 | sulfur amino acid catabolic process(GO:0000098) |
| 0.0 | 1.2 | GO:0051289 | protein homotetramerization(GO:0051289) |
| 0.0 | 0.3 | GO:0006301 | postreplication repair(GO:0006301) |
| 0.0 | 0.2 | GO:0042552 | myelination(GO:0042552) |
| 0.0 | 0.1 | GO:0003365 | establishment of cell polarity involved in ameboidal cell migration(GO:0003365) |
| 0.0 | 0.1 | GO:0018401 | peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401) |
| 0.0 | 0.8 | GO:0006635 | fatty acid beta-oxidation(GO:0006635) |
| 0.0 | 0.2 | GO:0016926 | protein desumoylation(GO:0016926) |
| 0.0 | 0.5 | GO:0033119 | negative regulation of RNA splicing(GO:0033119) |
| 0.0 | 0.5 | GO:0071359 | dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918) cellular response to dsRNA(GO:0071359) |
| 0.0 | 0.5 | GO:0000186 | activation of MAPKK activity(GO:0000186) |
| 0.0 | 1.5 | GO:0045667 | regulation of osteoblast differentiation(GO:0045667) |
| 0.0 | 1.0 | GO:0007601 | visual perception(GO:0007601) |
| 0.0 | 0.4 | GO:0000381 | regulation of alternative mRNA splicing, via spliceosome(GO:0000381) |
| 0.0 | 0.6 | GO:0007029 | endoplasmic reticulum organization(GO:0007029) |
| 0.0 | 1.0 | GO:0001649 | osteoblast differentiation(GO:0001649) |
| 0.0 | 0.2 | GO:0046597 | negative regulation of viral entry into host cell(GO:0046597) |
| 0.0 | 0.1 | GO:0035881 | amacrine cell differentiation(GO:0035881) |
| 0.0 | 0.2 | GO:2000060 | positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.5 | 7.3 | GO:0097226 | sperm mitochondrial sheath(GO:0097226) |
| 0.7 | 2.0 | GO:0042585 | germinal vesicle(GO:0042585) |
| 0.5 | 6.1 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.4 | 5.7 | GO:0046930 | pore complex(GO:0046930) |
| 0.3 | 1.7 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.3 | 1.0 | GO:0030905 | retromer, tubulation complex(GO:0030905) |
| 0.3 | 1.3 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.3 | 0.8 | GO:0097512 | cardiac myofibril(GO:0097512) |
| 0.2 | 1.4 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.2 | 2.4 | GO:0031232 | extrinsic component of external side of plasma membrane(GO:0031232) |
| 0.2 | 0.6 | GO:0031074 | nucleocytoplasmic shuttling complex(GO:0031074) |
| 0.2 | 0.9 | GO:0005784 | Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256) |
| 0.2 | 0.7 | GO:0043202 | lysosomal lumen(GO:0043202) |
| 0.2 | 2.1 | GO:0000276 | mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276) |
| 0.1 | 1.9 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.1 | 0.8 | GO:0044294 | dendritic growth cone(GO:0044294) |
| 0.1 | 1.5 | GO:0005832 | chaperonin-containing T-complex(GO:0005832) |
| 0.1 | 1.0 | GO:0031415 | NatA complex(GO:0031415) |
| 0.1 | 0.3 | GO:0048269 | methionine adenosyltransferase complex(GO:0048269) |
| 0.1 | 0.7 | GO:0000938 | GARP complex(GO:0000938) |
| 0.1 | 0.4 | GO:0033185 | dolichol-phosphate-mannose synthase complex(GO:0033185) |
| 0.1 | 1.2 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.1 | 0.7 | GO:0036195 | muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195) |
| 0.1 | 0.9 | GO:0032045 | guanyl-nucleotide exchange factor complex(GO:0032045) |
| 0.1 | 0.2 | GO:0016222 | procollagen-proline 4-dioxygenase complex(GO:0016222) |
| 0.1 | 1.0 | GO:0042582 | primary lysosome(GO:0005766) azurophil granule(GO:0042582) |
| 0.1 | 0.9 | GO:0070531 | BRCA1-A complex(GO:0070531) |
| 0.1 | 0.6 | GO:0060091 | kinocilium(GO:0060091) |
| 0.1 | 1.8 | GO:0000930 | gamma-tubulin complex(GO:0000930) |
| 0.1 | 0.9 | GO:0071598 | neuronal ribonucleoprotein granule(GO:0071598) |
| 0.1 | 0.4 | GO:0031265 | CD95 death-inducing signaling complex(GO:0031265) |
| 0.1 | 0.6 | GO:0042382 | paraspeckles(GO:0042382) |
| 0.1 | 2.5 | GO:0015030 | Cajal body(GO:0015030) |
| 0.1 | 1.0 | GO:0043196 | varicosity(GO:0043196) |
| 0.1 | 0.6 | GO:0005642 | annulate lamellae(GO:0005642) |
| 0.1 | 4.1 | GO:0005882 | intermediate filament(GO:0005882) |
| 0.1 | 0.7 | GO:0034663 | endoplasmic reticulum chaperone complex(GO:0034663) |
| 0.1 | 0.4 | GO:0042629 | mast cell granule(GO:0042629) |
| 0.0 | 2.3 | GO:0000307 | cyclin-dependent protein kinase holoenzyme complex(GO:0000307) |
| 0.0 | 0.4 | GO:0061617 | MICOS complex(GO:0061617) |
| 0.0 | 0.5 | GO:0044447 | axoneme part(GO:0044447) |
| 0.0 | 0.5 | GO:0048188 | MLL3/4 complex(GO:0044666) Set1C/COMPASS complex(GO:0048188) |
| 0.0 | 0.2 | GO:0033503 | HULC complex(GO:0033503) |
| 0.0 | 1.7 | GO:0045111 | intermediate filament cytoskeleton(GO:0045111) |
| 0.0 | 0.3 | GO:0019773 | proteasome core complex, alpha-subunit complex(GO:0019773) |
| 0.0 | 1.1 | GO:0032590 | dendrite membrane(GO:0032590) |
| 0.0 | 2.9 | GO:0005604 | basement membrane(GO:0005604) |
| 0.0 | 0.2 | GO:0042589 | zymogen granule membrane(GO:0042589) |
| 0.0 | 0.3 | GO:0071541 | eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541) |
| 0.0 | 0.4 | GO:0032156 | septin cytoskeleton(GO:0032156) |
| 0.0 | 0.2 | GO:0043203 | axon hillock(GO:0043203) |
| 0.0 | 0.2 | GO:0031467 | Cul7-RING ubiquitin ligase complex(GO:0031467) |
| 0.0 | 0.6 | GO:0005865 | striated muscle thin filament(GO:0005865) |
| 0.0 | 3.1 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.0 | 1.3 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 1.3 | GO:0031985 | Golgi cisterna(GO:0031985) |
| 0.0 | 0.4 | GO:0035145 | exon-exon junction complex(GO:0035145) |
| 0.0 | 0.7 | GO:0030904 | retromer complex(GO:0030904) |
| 0.0 | 2.4 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.0 | 0.4 | GO:0016580 | Sin3 complex(GO:0016580) |
| 0.0 | 0.8 | GO:0045335 | phagocytic vesicle(GO:0045335) |
| 0.0 | 0.2 | GO:0005922 | connexon complex(GO:0005922) |
| 0.0 | 0.7 | GO:0044295 | axonal growth cone(GO:0044295) |
| 0.0 | 1.3 | GO:0072562 | blood microparticle(GO:0072562) |
| 0.0 | 0.5 | GO:0001772 | immunological synapse(GO:0001772) |
| 0.0 | 0.9 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 0.7 | GO:0043209 | myelin sheath(GO:0043209) |
| 0.0 | 2.0 | GO:0016607 | nuclear speck(GO:0016607) |
| 0.0 | 0.4 | GO:0034451 | centriolar satellite(GO:0034451) |
| 0.0 | 0.3 | GO:0001669 | acrosomal vesicle(GO:0001669) |
| 0.0 | 0.7 | GO:0005793 | endoplasmic reticulum-Golgi intermediate compartment(GO:0005793) |
| 0.0 | 1.0 | GO:0005758 | mitochondrial intermembrane space(GO:0005758) |
| 0.0 | 0.9 | GO:0005881 | cytoplasmic microtubule(GO:0005881) |
| 0.0 | 0.3 | GO:0005680 | anaphase-promoting complex(GO:0005680) |
| 0.0 | 3.7 | GO:0043235 | receptor complex(GO:0043235) |
| 0.0 | 0.6 | GO:0045171 | intercellular bridge(GO:0045171) |
| 0.0 | 0.4 | GO:0005788 | endoplasmic reticulum lumen(GO:0005788) |
| 0.0 | 0.8 | GO:0005811 | lipid particle(GO:0005811) |
| 0.0 | 0.5 | GO:0030173 | integral component of Golgi membrane(GO:0030173) |
| 0.0 | 2.1 | GO:0005681 | spliceosomal complex(GO:0005681) |
| 0.0 | 4.1 | GO:0005667 | transcription factor complex(GO:0005667) |
| 0.0 | 1.2 | GO:0015934 | large ribosomal subunit(GO:0015934) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 7.3 | GO:0030911 | TPR domain binding(GO:0030911) |
| 0.9 | 2.8 | GO:0004566 | beta-glucuronidase activity(GO:0004566) |
| 0.7 | 2.2 | GO:0008502 | melatonin receptor activity(GO:0008502) |
| 0.7 | 2.2 | GO:0005118 | sevenless binding(GO:0005118) |
| 0.6 | 1.7 | GO:0070140 | isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140) |
| 0.6 | 1.7 | GO:0004155 | 6,7-dihydropteridine reductase activity(GO:0004155) |
| 0.5 | 1.6 | GO:0052740 | phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740) |
| 0.4 | 6.1 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.4 | 1.2 | GO:0034618 | arginine binding(GO:0034618) |
| 0.4 | 1.5 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.4 | 2.6 | GO:0005094 | Rho GDP-dissociation inhibitor activity(GO:0005094) |
| 0.4 | 1.5 | GO:0070573 | metallodipeptidase activity(GO:0070573) |
| 0.4 | 1.1 | GO:0035402 | histone kinase activity (H3-T11 specific)(GO:0035402) |
| 0.4 | 1.4 | GO:0004046 | aminoacylase activity(GO:0004046) |
| 0.3 | 0.9 | GO:0003956 | NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956) |
| 0.3 | 1.7 | GO:0008525 | phosphatidylcholine transporter activity(GO:0008525) |
| 0.3 | 2.0 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.3 | 1.0 | GO:0045131 | pre-mRNA branch point binding(GO:0045131) |
| 0.2 | 1.0 | GO:1990460 | leptin receptor binding(GO:1990460) |
| 0.2 | 0.7 | GO:0031686 | A1 adenosine receptor binding(GO:0031686) |
| 0.2 | 1.2 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.2 | 3.0 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
| 0.2 | 1.2 | GO:0032767 | copper-dependent protein binding(GO:0032767) |
| 0.2 | 0.7 | GO:0003953 | NAD+ nucleosidase activity(GO:0003953) |
| 0.2 | 1.3 | GO:0047276 | N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276) |
| 0.2 | 0.6 | GO:0004647 | phosphoserine phosphatase activity(GO:0004647) |
| 0.2 | 0.6 | GO:0050700 | CARD domain binding(GO:0050700) |
| 0.2 | 0.7 | GO:0042731 | PH domain binding(GO:0042731) |
| 0.2 | 0.5 | GO:0015234 | thiamine transmembrane transporter activity(GO:0015234) thiamine uptake transmembrane transporter activity(GO:0015403) |
| 0.2 | 1.3 | GO:0005021 | vascular endothelial growth factor-activated receptor activity(GO:0005021) |
| 0.2 | 0.9 | GO:0001069 | regulatory region RNA binding(GO:0001069) |
| 0.2 | 1.4 | GO:0043559 | insulin binding(GO:0043559) |
| 0.2 | 1.1 | GO:0070644 | vitamin D response element binding(GO:0070644) |
| 0.2 | 0.8 | GO:0005113 | patched binding(GO:0005113) |
| 0.2 | 0.6 | GO:0008073 | ornithine decarboxylase inhibitor activity(GO:0008073) |
| 0.1 | 1.0 | GO:0003876 | AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623) |
| 0.1 | 0.9 | GO:0051021 | GDP-dissociation inhibitor binding(GO:0051021) |
| 0.1 | 0.4 | GO:0047256 | beta-galactosyl-N-acetylglucosaminylgalactosylglucosyl-ceramide beta-1,3-acetylglucosaminyltransferase activity(GO:0008457) lactosylceramide 1,3-N-acetyl-beta-D-glucosaminyltransferase activity(GO:0047256) |
| 0.1 | 0.7 | GO:0047184 | 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184) |
| 0.1 | 0.6 | GO:0070883 | importin-alpha family protein binding(GO:0061676) pre-miRNA binding(GO:0070883) |
| 0.1 | 1.1 | GO:0031852 | mu-type opioid receptor binding(GO:0031852) |
| 0.1 | 0.7 | GO:0043176 | amine binding(GO:0043176) |
| 0.1 | 0.7 | GO:0000064 | L-ornithine transmembrane transporter activity(GO:0000064) |
| 0.1 | 0.8 | GO:0008193 | tRNA guanylyltransferase activity(GO:0008193) |
| 0.1 | 0.8 | GO:0046790 | virion binding(GO:0046790) |
| 0.1 | 1.0 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 0.4 | GO:0016018 | cyclosporin A binding(GO:0016018) |
| 0.1 | 0.4 | GO:0004582 | dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582) |
| 0.1 | 1.5 | GO:0016857 | racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857) |
| 0.1 | 3.6 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.1 | 1.2 | GO:0051400 | BH domain binding(GO:0051400) |
| 0.1 | 1.1 | GO:0005388 | calcium-transporting ATPase activity(GO:0005388) |
| 0.1 | 0.6 | GO:0042609 | CD4 receptor binding(GO:0042609) |
| 0.1 | 0.5 | GO:0001758 | retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028) |
| 0.1 | 1.4 | GO:0005035 | tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035) |
| 0.1 | 1.0 | GO:0004596 | peptide alpha-N-acetyltransferase activity(GO:0004596) |
| 0.1 | 1.5 | GO:0004550 | nucleoside diphosphate kinase activity(GO:0004550) |
| 0.1 | 2.4 | GO:0071837 | HMG box domain binding(GO:0071837) |
| 0.1 | 0.7 | GO:0048531 | beta-1,3-galactosyltransferase activity(GO:0048531) |
| 0.1 | 0.9 | GO:0042288 | MHC class I protein binding(GO:0042288) |
| 0.1 | 2.3 | GO:0017134 | fibroblast growth factor binding(GO:0017134) |
| 0.1 | 0.3 | GO:0070815 | peptidyl-lysine 5-dioxygenase activity(GO:0070815) |
| 0.1 | 0.5 | GO:0003836 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) |
| 0.1 | 0.4 | GO:0103116 | alpha-D-galactofuranose transporter activity(GO:0103116) |
| 0.1 | 0.2 | GO:0015038 | glutathione disulfide oxidoreductase activity(GO:0015038) |
| 0.1 | 0.6 | GO:0004806 | triglyceride lipase activity(GO:0004806) |
| 0.1 | 0.7 | GO:0004467 | long-chain fatty acid-CoA ligase activity(GO:0004467) decanoate--CoA ligase activity(GO:0102391) |
| 0.1 | 2.3 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 0.1 | 0.2 | GO:0004492 | methylmalonyl-CoA decarboxylase activity(GO:0004492) |
| 0.1 | 0.7 | GO:0001530 | lipopolysaccharide binding(GO:0001530) |
| 0.1 | 1.8 | GO:0043027 | cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) |
| 0.1 | 0.5 | GO:0043023 | ribosomal large subunit binding(GO:0043023) |
| 0.1 | 0.7 | GO:0031681 | G-protein beta-subunit binding(GO:0031681) |
| 0.1 | 0.3 | GO:1990932 | 5.8S rRNA binding(GO:1990932) |
| 0.0 | 0.1 | GO:0004307 | ethanolaminephosphotransferase activity(GO:0004307) |
| 0.0 | 2.3 | GO:0097472 | cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472) |
| 0.0 | 0.4 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.0 | 0.5 | GO:0030957 | Tat protein binding(GO:0030957) |
| 0.0 | 1.9 | GO:0045502 | dynein binding(GO:0045502) |
| 0.0 | 1.3 | GO:0003887 | DNA-directed DNA polymerase activity(GO:0003887) |
| 0.0 | 1.4 | GO:0031492 | nucleosomal DNA binding(GO:0031492) |
| 0.0 | 0.3 | GO:0001094 | TFIID-class transcription factor binding(GO:0001094) |
| 0.0 | 0.3 | GO:0019788 | NEDD8 transferase activity(GO:0019788) |
| 0.0 | 1.5 | GO:0004364 | glutathione transferase activity(GO:0004364) |
| 0.0 | 0.3 | GO:0055131 | C3HC4-type RING finger domain binding(GO:0055131) |
| 0.0 | 0.2 | GO:0015265 | urea channel activity(GO:0015265) |
| 0.0 | 0.9 | GO:0008422 | beta-glucosidase activity(GO:0008422) |
| 0.0 | 0.1 | GO:0019770 | IgG receptor activity(GO:0019770) |
| 0.0 | 1.1 | GO:0036002 | pre-mRNA binding(GO:0036002) |
| 0.0 | 0.3 | GO:0001972 | retinoic acid binding(GO:0001972) |
| 0.0 | 0.3 | GO:0008395 | steroid hydroxylase activity(GO:0008395) |
| 0.0 | 0.3 | GO:0008889 | glycerophosphodiester phosphodiesterase activity(GO:0008889) |
| 0.0 | 0.4 | GO:0070097 | delta-catenin binding(GO:0070097) |
| 0.0 | 0.1 | GO:0071987 | WD40-repeat domain binding(GO:0071987) |
| 0.0 | 0.2 | GO:0034711 | inhibin binding(GO:0034711) |
| 0.0 | 0.1 | GO:0004656 | procollagen-proline 4-dioxygenase activity(GO:0004656) |
| 0.0 | 0.7 | GO:0051879 | Hsp90 protein binding(GO:0051879) |
| 0.0 | 0.8 | GO:0000979 | RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979) |
| 0.0 | 0.1 | GO:0004145 | diamine N-acetyltransferase activity(GO:0004145) |
| 0.0 | 0.6 | GO:0005487 | nucleocytoplasmic transporter activity(GO:0005487) |
| 0.0 | 0.1 | GO:0015091 | ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510) |
| 0.0 | 0.9 | GO:0001046 | core promoter sequence-specific DNA binding(GO:0001046) |
| 0.0 | 0.2 | GO:0061665 | SUMO ligase activity(GO:0061665) |
| 0.0 | 0.2 | GO:0001727 | lipid kinase activity(GO:0001727) |
| 0.0 | 0.2 | GO:0005243 | gap junction channel activity(GO:0005243) |
| 0.0 | 0.2 | GO:0070181 | small ribosomal subunit rRNA binding(GO:0070181) |
| 0.0 | 0.4 | GO:0004707 | MAP kinase activity(GO:0004707) |
| 0.0 | 0.5 | GO:0042800 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) |
| 0.0 | 4.1 | GO:0003924 | GTPase activity(GO:0003924) |
| 0.0 | 1.1 | GO:0003684 | damaged DNA binding(GO:0003684) |
| 0.0 | 0.1 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.0 | 0.4 | GO:0034946 | 2-oxoglutaryl-CoA thioesterase activity(GO:0034843) 2,4,4-trimethyl-3-oxopentanoyl-CoA thioesterase activity(GO:0034869) 3-isopropylbut-3-enoyl-CoA thioesterase activity(GO:0034946) glutaryl-CoA hydrolase activity(GO:0044466) |
| 0.0 | 1.3 | GO:0005080 | protein kinase C binding(GO:0005080) |
| 0.0 | 0.2 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |
| 0.0 | 7.0 | GO:0001228 | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228) |
| 0.0 | 0.7 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
| 0.0 | 3.2 | GO:0030246 | carbohydrate binding(GO:0030246) |
| 0.0 | 0.6 | GO:0030544 | Hsp70 protein binding(GO:0030544) |
| 0.0 | 0.2 | GO:0031386 | protein tag(GO:0031386) |
| 0.0 | 0.1 | GO:0016668 | oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor(GO:0016668) |
| 0.0 | 0.2 | GO:0016929 | SUMO-specific protease activity(GO:0016929) |
| 0.0 | 0.3 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 0.6 | GO:0016831 | carboxy-lyase activity(GO:0016831) |
| 0.0 | 1.4 | GO:0015078 | hydrogen ion transmembrane transporter activity(GO:0015078) |
| 0.0 | 0.1 | GO:0002151 | G-quadruplex RNA binding(GO:0002151) |
| 0.0 | 0.6 | GO:0004120 | calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715) |
| 0.0 | 0.5 | GO:0004709 | MAP kinase kinase kinase activity(GO:0004709) |
| 0.0 | 1.3 | GO:0005178 | integrin binding(GO:0005178) |
| 0.0 | 0.7 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 0.1 | GO:1990226 | histone methyltransferase binding(GO:1990226) |
| 0.0 | 0.3 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
