Motif ID: Id4

Z-value: 0.967


Transcription factors associated with Id4:

Gene SymbolEntrez IDGene Name
Id4 ENSMUSG00000021379.1 Id4

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Id4mm10_v2_chr13_+_48261427_48261427-0.133.1e-01Click!


Activity profile for motif Id4.

activity profile for motif Id4


Sorted Z-values histogram for motif Id4

Sorted Z-values for motif Id4



Network of associatons between targets according to the STRING database.



First level regulatory network of Id4

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_164458345 8.453 ENSMUST00000027863.7
 Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr16_+_91269759 7.560 ENSMUST00000056882.5
 Olig1
oligodendrocyte transcription factor 1
chr15_+_99717515 6.272 ENSMUST00000023760.6
ENSMUST00000162194.1
 Gpd1

glycerol-3-phosphate dehydrogenase 1 (soluble)

chr19_-_42202150 5.875 ENSMUST00000018966.7
 Sfrp5
secreted frizzled-related sequence protein 5
chr14_+_54936456 5.760 ENSMUST00000037814.6
 Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr11_+_3488275 5.530 ENSMUST00000064265.6
 Pla2g3
phospholipase A2, group III
chr5_+_17574726 5.443 ENSMUST00000169603.1
 Sema3c
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr3_+_90537306 5.299 ENSMUST00000107335.1
 S100a16
S100 calcium binding protein A16
chr3_+_90537242 5.267 ENSMUST00000098911.3
 S100a16
S100 calcium binding protein A16
chr11_-_69605829 5.183 ENSMUST00000047889.6
 Atp1b2
ATPase, Na+/K+ transporting, beta 2 polypeptide
chr14_-_103843685 5.117 ENSMUST00000172237.1
 Ednrb
endothelin receptor type B
chr1_+_86045863 5.034 ENSMUST00000165824.1
 2810459M11Rik
RIKEN cDNA 2810459M11 gene
chr17_-_25570678 4.786 ENSMUST00000025003.3
ENSMUST00000173447.1
 Sox8

SRY-box containing gene 8

chr16_+_11984581 4.745 ENSMUST00000170672.2
ENSMUST00000023138.7
 Shisa9

shisa homolog 9 (Xenopus laevis)

chr11_+_115163333 4.725 ENSMUST00000021077.3
 Slc9a3r1
solute carrier family 9 (sodium/hydrogen exchanger), member 3 regulator 1
chr8_-_70439557 4.659 ENSMUST00000076615.5
 Crtc1
CREB regulated transcription coactivator 1
chr2_-_122611238 4.647 ENSMUST00000028624.8
 Gatm
glycine amidinotransferase (L-arginine:glycine amidinotransferase)
chr11_-_107915041 4.541 ENSMUST00000039071.2
 Cacng5
calcium channel, voltage-dependent, gamma subunit 5
chr2_-_125723387 4.515 ENSMUST00000042246.7
 Shc4
SHC (Src homology 2 domain containing) family, member 4
chr11_+_61956779 4.480 ENSMUST00000049836.7
 Specc1
sperm antigen with calponin homology and coiled-coil domains 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 347 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.4 13.6 GO:1903288 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.5 13.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
3.8 11.5 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
2.2 8.7 GO:0014043 negative regulation of neuron maturation(GO:0014043)
2.8 8.4 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
1.6 8.1 GO:1900085 negative regulation of peptidyl-tyrosine autophosphorylation(GO:1900085)
0.2 7.4 GO:0036465 synaptic vesicle recycling(GO:0036465)
0.5 7.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
2.4 7.2 GO:1904049 regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
1.0 6.9 GO:0034047 regulation of protein phosphatase type 2A activity(GO:0034047)
1.3 6.6 GO:0032911 negative regulation of transforming growth factor beta1 production(GO:0032911)
1.1 6.6 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.6 6.3 GO:0019372 lipoxygenase pathway(GO:0019372)
0.3 6.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
2.0 5.9 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.4 5.9 GO:0042182 ketone catabolic process(GO:0042182)
1.1 5.7 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.8 5.4 GO:0060666 dichotomous subdivision of terminal units involved in salivary gland branching(GO:0060666)
0.3 4.8 GO:0010640 regulation of platelet-derived growth factor receptor signaling pathway(GO:0010640)
0.2 4.8 GO:0045475 locomotor rhythm(GO:0045475)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 143 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 14.6 GO:0031965 nuclear membrane(GO:0031965)
1.9 13.6 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.3 11.5 GO:0090544 BAF-type complex(GO:0090544)
0.0 9.7 GO:0045211 postsynaptic membrane(GO:0045211)
0.6 8.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
1.7 8.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.0 8.4 GO:0005802 trans-Golgi network(GO:0005802)
0.0 8.0 GO:0005667 transcription factor complex(GO:0005667)
1.5 7.7 GO:1990761 growth cone lamellipodium(GO:1990761)
0.2 7.6 GO:0032809 neuronal cell body membrane(GO:0032809)
0.4 6.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.2 6.7 GO:0048786 presynaptic active zone(GO:0048786)
1.4 5.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.2 5.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 5.1 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.9 4.7 GO:0032426 stereocilium tip(GO:0032426)
0.8 4.7 GO:0016011 dystroglycan complex(GO:0016011)
0.5 4.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.5 4.7 GO:0032591 dendritic spine membrane(GO:0032591)
0.1 4.7 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 248 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 14.3 GO:0051015 actin filament binding(GO:0051015)
1.4 13.6 GO:0008556 sodium:potassium-exchanging ATPase activity(GO:0005391) potassium-transporting ATPase activity(GO:0008556)
0.0 11.9 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.5 10.1 GO:0042813 Wnt-activated receptor activity(GO:0042813)
2.9 8.7 GO:0004962 endothelin receptor activity(GO:0004962)
0.6 8.6 GO:0051393 alpha-actinin binding(GO:0051393)
1.6 8.1 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.5 6.9 GO:0008601 protein phosphatase type 2A regulator activity(GO:0008601)
0.3 6.8 GO:0008157 protein phosphatase 1 binding(GO:0008157)
2.1 6.3 GO:0004368 glycerol-3-phosphate dehydrogenase activity(GO:0004368)
0.2 6.1 GO:0043014 alpha-tubulin binding(GO:0043014)
0.8 5.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
1.0 4.9 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 4.8 GO:0042805 actinin binding(GO:0042805)
0.5 4.7 GO:0004383 guanylate cyclase activity(GO:0004383)
0.5 4.7 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.5 4.7 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 4.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.1 4.4 GO:0004120 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118) cGMP-inhibited cyclic-nucleotide phosphodiesterase activity(GO:0004119) photoreceptor cyclic-nucleotide phosphodiesterase activity(GO:0004120) 7,8-dihydro-D-neopterin 2',3'-cyclic phosphate phosphodiesterase activity(GO:0044688) inositol phosphosphingolipid phospholipase activity(GO:0052712) inositol phosphorylceramide phospholipase activity(GO:0052713) mannosyl-inositol phosphorylceramide phospholipase activity(GO:0052714) mannosyl-diinositol phosphorylceramide phospholipase activity(GO:0052715)
1.4 4.3 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715)