Motif ID: Ikzf2

Z-value: 0.897


Transcription factors associated with Ikzf2:

Gene SymbolEntrez IDGene Name
Ikzf2 ENSMUSG00000025997.7 Ikzf2

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Ikzf2mm10_v2_chr1_-_69685937_696859660.085.2e-01Click!


Activity profile for motif Ikzf2.

activity profile for motif Ikzf2


Sorted Z-values histogram for motif Ikzf2

Sorted Z-values for motif Ikzf2



Network of associatons between targets according to the STRING database.



First level regulatory network of Ikzf2

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Top targets:


Showing 1 to 20 of 117 entries
PromoterScoreRefseqGene SymbolGene Name
chr6_-_23248264 19.728 ENSMUST00000031709.5
 Fezf1
Fez family zinc finger 1
chr15_+_3270767 13.520 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
 Sepp1



selenoprotein P, plasma, 1



chrX_+_103422010 10.063 ENSMUST00000182089.1
 Gm26992
predicted gene, 26992
chr6_+_4003926 6.819 ENSMUST00000031670.8
 Gng11
guanine nucleotide binding protein (G protein), gamma 11
chr19_+_55894508 6.322 ENSMUST00000142291.1
 Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr4_+_105157339 5.581 ENSMUST00000064139.7
 Ppap2b
phosphatidic acid phosphatase type 2B
chr12_+_75308308 5.332 ENSMUST00000118602.1
ENSMUST00000118966.1
ENSMUST00000055390.5
 Rhoj


ras homolog gene family, member J


chr1_+_45311538 4.611 ENSMUST00000087883.6
 Col3a1
collagen, type III, alpha 1
chr5_+_92897981 4.518 ENSMUST00000113051.2
 Shroom3
shroom family member 3
chr14_+_54936456 4.373 ENSMUST00000037814.6
 Cmtm5
CKLF-like MARVEL transmembrane domain containing 5
chr1_-_45503282 4.174 ENSMUST00000086430.4
 Col5a2
collagen, type V, alpha 2
chr1_-_162866502 4.083 ENSMUST00000046049.7
 Fmo1
flavin containing monooxygenase 1
chr13_+_89540636 4.066 ENSMUST00000022108.7
 Hapln1
hyaluronan and proteoglycan link protein 1
chr7_-_70360593 4.026 ENSMUST00000032768.7
 Nr2f2
nuclear receptor subfamily 2, group F, member 2
chr3_-_154330543 4.022 ENSMUST00000184966.1
ENSMUST00000177846.2
 Lhx8

LIM homeobox protein 8

chr11_-_55419898 3.850 ENSMUST00000108858.1
ENSMUST00000141530.1
 Sparc

secreted acidic cysteine rich glycoprotein

chr5_+_110330697 3.592 ENSMUST00000112481.1
 Pole
polymerase (DNA directed), epsilon
chr7_-_139582790 3.519 ENSMUST00000106095.2
 Nkx6-2
NK6 homeobox 2
chr4_+_57637816 3.397 ENSMUST00000150412.1
 Gm20459
predicted gene 20459
chr3_-_116129615 3.377 ENSMUST00000029574.8
 Vcam1
vascular cell adhesion molecule 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 61 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.3 19.7 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
1.9 13.5 GO:0001887 selenium compound metabolic process(GO:0001887)
0.0 7.4 GO:0007186 G-protein coupled receptor signaling pathway(GO:0007186)
0.8 6.3 GO:0048625 myoblast fate commitment(GO:0048625)
0.4 5.3 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.9 4.6 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 4.5 GO:0002066 columnar/cuboidal epithelial cell development(GO:0002066)
0.2 4.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
1.4 4.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.5 4.1 GO:0009404 toxin metabolic process(GO:0009404)
0.0 4.1 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
2.0 4.0 GO:0060838 lymphatic endothelial cell fate commitment(GO:0060838) regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 4.0 GO:0021884 forebrain neuron development(GO:0021884)
0.1 3.9 GO:0001937 negative regulation of endothelial cell proliferation(GO:0001937)
0.6 3.6 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.5 3.5 GO:0021913 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912) regulation of transcription from RNA polymerase II promoter involved in ventral spinal cord interneuron specification(GO:0021913)
1.1 3.4 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.3 3.4 GO:0042447 hormone catabolic process(GO:0042447)
0.3 3.4 GO:0061032 visceral serous pericardium development(GO:0061032)
0.0 3.4 GO:0006869 lipid transport(GO:0006869)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 37 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 11.4 GO:0005615 extracellular space(GO:0005615)
0.2 7.6 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.7 6.3 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.2 5.7 GO:0002102 podosome(GO:0002102)
0.5 4.6 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 4.6 GO:0005813 centrosome(GO:0005813)
0.0 4.5 GO:0016324 apical plasma membrane(GO:0016324)
1.4 4.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 4.1 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.7 4.0 GO:0001674 female germ cell nucleus(GO:0001674)
1.0 3.9 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 3.8 GO:0036064 ciliary basal body(GO:0036064)
0.1 3.7 GO:0032590 dendrite membrane(GO:0032590)
0.7 3.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 3.6 GO:0005581 collagen trimer(GO:0005581)
0.0 3.4 GO:0005811 lipid particle(GO:0005811)
0.0 3.0 GO:0005681 spliceosomal complex(GO:0005681)
0.0 2.7 GO:0043209 myelin sheath(GO:0043209)
0.0 2.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 2.3 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 43 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 26.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.5 16.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.9 13.5 GO:0008430 selenium binding(GO:0008430)
0.1 7.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.3 6.3 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 6.0 GO:0051015 actin filament binding(GO:0051015)
0.0 5.3 GO:0003924 GTPase activity(GO:0003924)
0.8 4.1 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.0 4.1 GO:0042626 ATPase activity, coupled to transmembrane movement of substances(GO:0042626)
0.4 4.0 GO:0001972 retinoic acid binding(GO:0001972)
0.4 4.0 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 3.9 GO:0050840 extracellular matrix binding(GO:0050840)
0.1 3.6 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 3.5 GO:0003727 single-stranded RNA binding(GO:0003727)
0.8 3.4 GO:0008131 primary amine oxidase activity(GO:0008131)
0.5 3.4 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.2 3.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.5 3.1 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.1 2.8 GO:0043015 gamma-tubulin binding(GO:0043015)
0.2 2.7 GO:0016151 nickel cation binding(GO:0016151)