Motif ID: Insm1
Z-value: 0.824
Transcription factors associated with Insm1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Insm1 | ENSMUSG00000068154.4 | Insm1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Insm1 | mm10_v2_chr2_+_146221921_146221921 | 0.85 | 2.9e-17 | Click! |
Top targets:
Gene overrepresentation in biological_process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 9.1 | GO:1901254 | positive regulation of intracellular transport of viral material(GO:1901254) |
| 1.6 | 4.8 | GO:1904049 | regulation of spontaneous neurotransmitter secretion(GO:1904048) negative regulation of spontaneous neurotransmitter secretion(GO:1904049) |
| 1.1 | 6.5 | GO:0061343 | cell adhesion involved in heart morphogenesis(GO:0061343) |
| 0.7 | 2.7 | GO:0034454 | microtubule anchoring at centrosome(GO:0034454) |
| 0.7 | 4.6 | GO:0036072 | intramembranous ossification(GO:0001957) direct ossification(GO:0036072) |
| 0.6 | 6.3 | GO:0048149 | behavioral response to ethanol(GO:0048149) |
| 0.5 | 1.4 | GO:0030070 | insulin processing(GO:0030070) |
| 0.5 | 3.2 | GO:1905206 | positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206) |
| 0.4 | 2.2 | GO:0042636 | negative regulation of hair cycle(GO:0042636) progesterone secretion(GO:0042701) negative regulation of hair follicle development(GO:0051799) positive regulation of ovulation(GO:0060279) |
| 0.4 | 4.4 | GO:0007379 | segment specification(GO:0007379) |
| 0.4 | 4.8 | GO:0046543 | development of secondary female sexual characteristics(GO:0046543) |
| 0.4 | 3.5 | GO:0005513 | detection of calcium ion(GO:0005513) |
| 0.4 | 1.3 | GO:0060489 | establishment of body hair or bristle planar orientation(GO:0048104) establishment of body hair planar orientation(GO:0048105) orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346) |
| 0.4 | 4.5 | GO:0023041 | neuronal signal transduction(GO:0023041) |
| 0.4 | 2.0 | GO:1900095 | regulation of dosage compensation by inactivation of X chromosome(GO:1900095) |
| 0.4 | 1.6 | GO:0061428 | positive regulation of oocyte development(GO:0060282) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) |
| 0.4 | 1.1 | GO:0016561 | protein import into peroxisome matrix, translocation(GO:0016561) |
| 0.4 | 2.2 | GO:0007253 | cytoplasmic sequestering of NF-kappaB(GO:0007253) |
| 0.3 | 1.3 | GO:0070127 | tRNA aminoacylation for mitochondrial protein translation(GO:0070127) |
| 0.3 | 1.3 | GO:0046898 | response to cycloheximide(GO:0046898) |
| 0.3 | 1.9 | GO:0007197 | adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207) |
| 0.3 | 1.2 | GO:2001032 | regulation of double-strand break repair via nonhomologous end joining(GO:2001032) |
| 0.3 | 0.8 | GO:2000569 | T-helper 2 cell activation(GO:0035712) positive regulation of T-helper 17 type immune response(GO:2000318) regulation of T-helper 2 cell activation(GO:2000569) positive regulation of T-helper 2 cell activation(GO:2000570) |
| 0.3 | 11.8 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
| 0.2 | 3.9 | GO:0060712 | spongiotrophoblast layer development(GO:0060712) |
| 0.2 | 22.7 | GO:0007631 | feeding behavior(GO:0007631) |
| 0.2 | 0.8 | GO:0043974 | histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674) |
| 0.2 | 4.0 | GO:0048266 | behavioral response to pain(GO:0048266) |
| 0.2 | 0.8 | GO:0021993 | initiation of neural tube closure(GO:0021993) |
| 0.2 | 3.9 | GO:0007205 | protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205) |
| 0.2 | 1.3 | GO:0045607 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
| 0.2 | 0.5 | GO:0048162 | preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162) |
| 0.2 | 7.1 | GO:0031572 | G2 DNA damage checkpoint(GO:0031572) |
| 0.1 | 2.7 | GO:0014898 | muscle hypertrophy in response to stress(GO:0003299) cardiac muscle hypertrophy in response to stress(GO:0014898) |
| 0.1 | 3.0 | GO:0032011 | ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012) |
| 0.1 | 1.6 | GO:0009312 | oligosaccharide biosynthetic process(GO:0009312) |
| 0.1 | 10.1 | GO:0050885 | neuromuscular process controlling balance(GO:0050885) |
| 0.1 | 3.1 | GO:0006904 | vesicle docking involved in exocytosis(GO:0006904) |
| 0.1 | 0.7 | GO:2000786 | positive regulation of autophagosome assembly(GO:2000786) |
| 0.1 | 2.3 | GO:0033622 | integrin activation(GO:0033622) |
| 0.1 | 3.2 | GO:0060997 | dendritic spine morphogenesis(GO:0060997) |
| 0.1 | 6.4 | GO:0051965 | positive regulation of synapse assembly(GO:0051965) |
| 0.1 | 2.5 | GO:0048791 | calcium ion-regulated exocytosis of neurotransmitter(GO:0048791) |
| 0.1 | 0.6 | GO:0097264 | self proteolysis(GO:0097264) |
| 0.1 | 8.0 | GO:0014065 | phosphatidylinositol 3-kinase signaling(GO:0014065) |
| 0.1 | 1.5 | GO:1901897 | regulation of relaxation of cardiac muscle(GO:1901897) |
| 0.1 | 0.5 | GO:0043353 | enucleate erythrocyte differentiation(GO:0043353) |
| 0.1 | 0.8 | GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928) |
| 0.1 | 2.5 | GO:0048843 | negative regulation of axon extension involved in axon guidance(GO:0048843) negative chemotaxis(GO:0050919) |
| 0.1 | 1.3 | GO:0045724 | positive regulation of cilium assembly(GO:0045724) |
| 0.0 | 1.0 | GO:0008214 | protein demethylation(GO:0006482) protein dealkylation(GO:0008214) |
| 0.0 | 0.5 | GO:0043374 | CD8-positive, alpha-beta T cell differentiation(GO:0043374) |
| 0.0 | 0.8 | GO:0043153 | entrainment of circadian clock by photoperiod(GO:0043153) |
| 0.0 | 3.7 | GO:0060041 | retina development in camera-type eye(GO:0060041) |
| 0.0 | 0.3 | GO:0060670 | branching involved in labyrinthine layer morphogenesis(GO:0060670) |
| 0.0 | 1.1 | GO:0006378 | mRNA polyadenylation(GO:0006378) |
| 0.0 | 0.2 | GO:0019227 | neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870) |
| 0.0 | 0.8 | GO:0032922 | circadian regulation of gene expression(GO:0032922) |
| 0.0 | 0.2 | GO:0031987 | locomotion involved in locomotory behavior(GO:0031987) |
| 0.0 | 0.2 | GO:0072520 | seminiferous tubule development(GO:0072520) |
| 0.0 | 0.0 | GO:1903795 | regulation of inorganic anion transmembrane transport(GO:1903795) |
| 0.0 | 1.6 | GO:0035023 | regulation of Rho protein signal transduction(GO:0035023) |
| 0.0 | 0.1 | GO:0019985 | translesion synthesis(GO:0019985) |
Gene overrepresentation in cellular_component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 3.0 | 9.1 | GO:0042025 | viral replication complex(GO:0019034) host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094) |
| 2.0 | 10.1 | GO:0030314 | junctional membrane complex(GO:0030314) |
| 1.0 | 4.8 | GO:1990761 | growth cone lamellipodium(GO:1990761) |
| 0.7 | 2.2 | GO:0043512 | inhibin A complex(GO:0043512) |
| 0.5 | 2.6 | GO:0036449 | microtubule minus-end(GO:0036449) |
| 0.3 | 1.3 | GO:0060187 | cell pole(GO:0060187) |
| 0.3 | 11.8 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
| 0.3 | 1.6 | GO:0033010 | paranodal junction(GO:0033010) |
| 0.2 | 2.0 | GO:0072669 | tRNA-splicing ligase complex(GO:0072669) |
| 0.2 | 3.1 | GO:0000145 | exocyst(GO:0000145) |
| 0.2 | 1.2 | GO:0001940 | male pronucleus(GO:0001940) |
| 0.2 | 1.3 | GO:0097136 | Bcl-2 family protein complex(GO:0097136) |
| 0.2 | 18.8 | GO:0031225 | anchored component of membrane(GO:0031225) |
| 0.1 | 1.9 | GO:0032279 | asymmetric synapse(GO:0032279) |
| 0.1 | 0.2 | GO:0005828 | kinetochore microtubule(GO:0005828) |
| 0.1 | 7.3 | GO:0008076 | voltage-gated potassium channel complex(GO:0008076) |
| 0.1 | 4.5 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.1 | 4.4 | GO:0008023 | transcription elongation factor complex(GO:0008023) |
| 0.1 | 0.3 | GO:0070436 | Grb2-EGFR complex(GO:0070436) |
| 0.1 | 0.6 | GO:0031428 | box C/D snoRNP complex(GO:0031428) |
| 0.0 | 1.1 | GO:0005782 | peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907) |
| 0.0 | 7.1 | GO:0008021 | synaptic vesicle(GO:0008021) |
| 0.0 | 0.8 | GO:0030014 | CCR4-NOT complex(GO:0030014) |
| 0.0 | 3.9 | GO:0000922 | spindle pole(GO:0000922) |
| 0.0 | 3.2 | GO:0043204 | perikaryon(GO:0043204) |
| 0.0 | 0.8 | GO:0071339 | MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339) |
| 0.0 | 1.3 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.5 | GO:0005839 | proteasome core complex(GO:0005839) |
| 0.0 | 1.5 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 2.5 | GO:0098793 | presynapse(GO:0098793) |
| 0.0 | 1.5 | GO:0016529 | sarcoplasmic reticulum(GO:0016529) |
| 0.0 | 0.8 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.0 | 2.0 | GO:0001726 | ruffle(GO:0001726) |
| 0.0 | 0.8 | GO:0031519 | PcG protein complex(GO:0031519) |
| 0.0 | 5.2 | GO:0005925 | focal adhesion(GO:0005925) |
Gene overrepresentation in molecular_function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.8 | 9.1 | GO:1990825 | sequence-specific mRNA binding(GO:1990825) |
| 0.4 | 1.6 | GO:0034739 | histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903) |
| 0.4 | 11.1 | GO:0008157 | protein phosphatase 1 binding(GO:0008157) |
| 0.4 | 7.1 | GO:0050321 | tau-protein kinase activity(GO:0050321) |
| 0.4 | 2.2 | GO:0070699 | type II activin receptor binding(GO:0070699) |
| 0.4 | 3.9 | GO:0004143 | diacylglycerol kinase activity(GO:0004143) |
| 0.3 | 7.4 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
| 0.3 | 1.9 | GO:0016907 | G-protein coupled acetylcholine receptor activity(GO:0016907) |
| 0.2 | 3.0 | GO:0070679 | inositol 1,4,5 trisphosphate binding(GO:0070679) |
| 0.2 | 1.6 | GO:0001665 | alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665) |
| 0.2 | 3.5 | GO:0015269 | calcium-activated potassium channel activity(GO:0015269) |
| 0.2 | 1.1 | GO:0005052 | peroxisome matrix targeting signal-1 binding(GO:0005052) |
| 0.2 | 1.4 | GO:0070191 | methionine-R-sulfoxide reductase activity(GO:0070191) |
| 0.2 | 1.3 | GO:0051434 | BH3 domain binding(GO:0051434) |
| 0.2 | 1.1 | GO:0004652 | polynucleotide adenylyltransferase activity(GO:0004652) |
| 0.1 | 0.6 | GO:0034511 | U3 snoRNA binding(GO:0034511) |
| 0.1 | 4.5 | GO:0001540 | beta-amyloid binding(GO:0001540) |
| 0.1 | 0.9 | GO:0005212 | structural constituent of eye lens(GO:0005212) |
| 0.1 | 3.9 | GO:0004869 | cysteine-type endopeptidase inhibitor activity(GO:0004869) |
| 0.1 | 3.2 | GO:0001221 | transcription cofactor binding(GO:0001221) |
| 0.1 | 2.5 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.1 | 0.4 | GO:0008599 | protein phosphatase type 1 regulator activity(GO:0008599) |
| 0.1 | 1.3 | GO:0097602 | cullin family protein binding(GO:0097602) |
| 0.1 | 2.5 | GO:0005544 | calcium-dependent phospholipid binding(GO:0005544) |
| 0.1 | 4.0 | GO:0015459 | potassium channel regulator activity(GO:0015459) |
| 0.1 | 11.5 | GO:0050839 | cell adhesion molecule binding(GO:0050839) |
| 0.0 | 0.8 | GO:0051864 | histone demethylase activity (H3-K36 specific)(GO:0051864) |
| 0.0 | 1.0 | GO:0051723 | protein methylesterase activity(GO:0051723) |
| 0.0 | 0.8 | GO:0004535 | poly(A)-specific ribonuclease activity(GO:0004535) |
| 0.0 | 1.5 | GO:0004683 | calmodulin-dependent protein kinase activity(GO:0004683) |
| 0.0 | 0.8 | GO:0070577 | histone methyltransferase activity (H3-K4 specific)(GO:0042800) lysine-acetylated histone binding(GO:0070577) |
| 0.0 | 3.2 | GO:0008013 | beta-catenin binding(GO:0008013) |
| 0.0 | 0.2 | GO:0008597 | calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597) |
| 0.0 | 1.3 | GO:0004812 | aminoacyl-tRNA ligase activity(GO:0004812) |
| 0.0 | 2.3 | GO:0043851 | rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA methyltransferase activity(GO:0008649) rRNA (uridine-2'-O-)-methyltransferase activity(GO:0008650) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988) rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383) selenocysteine methyltransferase activity(GO:0016205) rRNA (adenine) methyltransferase activity(GO:0016433) rRNA (cytosine) methyltransferase activity(GO:0016434) rRNA (guanine) methyltransferase activity(GO:0016435) rRNA (uridine) methyltransferase activity(GO:0016436) 1-phenanthrol methyltransferase activity(GO:0018707) protein-arginine N5-methyltransferase activity(GO:0019702) dimethylarsinite methyltransferase activity(GO:0034541) 4,5-dihydroxybenzo(a)pyrene methyltransferase activity(GO:0034807) 1-hydroxypyrene methyltransferase activity(GO:0034931) 1-hydroxy-6-methoxypyrene methyltransferase activity(GO:0034933) demethylmenaquinone methyltransferase activity(GO:0043770) cobalt-precorrin-6B C5-methyltransferase activity(GO:0043776) cobalt-precorrin-7 C15-methyltransferase activity(GO:0043777) cobalt-precorrin-5B C1-methyltransferase activity(GO:0043780) cobalt-precorrin-3 C17-methyltransferase activity(GO:0043782) dimethylamine methyltransferase activity(GO:0043791) hydroxyneurosporene-O-methyltransferase activity(GO:0043803) tRNA (adenine-57, 58-N(1)-) methyltransferase activity(GO:0043827) methylamine-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043833) trimethylamine methyltransferase activity(GO:0043834) methanol-specific methylcobalamin:coenzyme M methyltransferase activity(GO:0043851) monomethylamine methyltransferase activity(GO:0043852) P-methyltransferase activity(GO:0051994) Se-methyltransferase activity(GO:0051995) 2-phytyl-1,4-naphthoquinone methyltransferase activity(GO:0052624) tRNA (uracil-2'-O-)-methyltransferase activity(GO:0052665) tRNA (cytosine-2'-O-)-methyltransferase activity(GO:0052666) phosphomethylethanolamine N-methyltransferase activity(GO:0052667) tRNA (cytosine-3-)-methyltransferase activity(GO:0052735) rRNA (cytosine-2'-O-)-methyltransferase activity(GO:0070677) rRNA (cytosine-N4-)-methyltransferase activity(GO:0071424) trihydroxyferuloyl spermidine O-methyltransferase activity(GO:0080012) |
| 0.0 | 0.3 | GO:0043560 | insulin receptor substrate binding(GO:0043560) |
| 0.0 | 0.5 | GO:0004298 | threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003) |
| 0.0 | 1.4 | GO:0004402 | histone acetyltransferase activity(GO:0004402) |
| 0.0 | 2.5 | GO:0042826 | histone deacetylase binding(GO:0042826) |
| 0.0 | 0.2 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.0 | 1.6 | GO:0005089 | Rho guanyl-nucleotide exchange factor activity(GO:0005089) |
| 0.0 | 0.4 | GO:0004697 | protein kinase C activity(GO:0004697) |
| 0.0 | 0.2 | GO:0005247 | voltage-gated chloride channel activity(GO:0005247) |
| 0.0 | 0.5 | GO:0005160 | transforming growth factor beta receptor binding(GO:0005160) |
