Motif ID: Irf4

Z-value: 0.686


Transcription factors associated with Irf4:

Gene SymbolEntrez IDGene Name
Irf4 ENSMUSG00000021356.3 Irf4



Activity profile for motif Irf4.

activity profile for motif Irf4


Sorted Z-values histogram for motif Irf4

Sorted Z-values for motif Irf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Irf4

PNG image of the network

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Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr3_+_90537242 7.068 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr3_+_90537306 6.910 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr1_-_163313661 5.401 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
Prrx1


paired related homeobox 1


chr3_-_142395661 3.508 ENSMUST00000029941.9
ENSMUST00000168967.2
ENSMUST00000090134.5
ENSMUST00000058626.8
Pdlim5



PDZ and LIM domain 5



chr11_-_77894096 3.461 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr10_+_128706251 3.221 ENSMUST00000054125.8
Pmel
premelanosome protein
chr19_-_58454580 3.126 ENSMUST00000129100.1
ENSMUST00000123957.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr6_-_87335758 3.122 ENSMUST00000042025.9
Antxr1
anthrax toxin receptor 1
chr19_-_24225015 2.861 ENSMUST00000099558.4
Tjp2
tight junction protein 2
chr19_-_58455161 2.788 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr6_+_82041623 2.756 ENSMUST00000042974.8
Eva1a
eva-1 homolog A (C. elegans)
chr6_-_97060407 2.668 ENSMUST00000089295.4
Fam19a4
family with sequence similarity 19, member A4
chr6_-_39118211 2.663 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr19_-_58455398 2.583 ENSMUST00000026076.7
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr1_+_66468364 2.479 ENSMUST00000061620.9
Unc80
unc-80 homolog (C. elegans)
chr19_+_56397100 2.407 ENSMUST00000026062.9
Casp7
caspase 7
chr4_-_89311021 2.407 ENSMUST00000097981.4
Cdkn2b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr1_+_61638819 2.400 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr14_-_66124482 2.399 ENSMUST00000070515.1
Ephx2
epoxide hydrolase 2, cytoplasmic
chr7_-_141010759 2.354 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3
chr10_+_94575257 2.344 ENSMUST00000121471.1
Tmcc3
transmembrane and coiled coil domains 3
chr2_-_127788854 2.326 ENSMUST00000028857.7
ENSMUST00000110357.1
Nphp1

nephronophthisis 1 (juvenile) homolog (human)

chr11_+_119393060 2.224 ENSMUST00000131035.2
ENSMUST00000093902.5
Rnf213

ring finger protein 213

chr13_-_113046357 2.126 ENSMUST00000022282.3
Gpx8
glutathione peroxidase 8 (putative)
chr9_+_85842852 2.119 ENSMUST00000098500.3
Tpbg
trophoblast glycoprotein
chr6_+_71282280 2.014 ENSMUST00000080949.7
Krcc1
lysine-rich coiled-coil 1
chr9_-_116175318 1.973 ENSMUST00000061101.4
ENSMUST00000035014.6
Tgfbr2

transforming growth factor, beta receptor II

chr7_+_58658181 1.964 ENSMUST00000168747.1
Atp10a
ATPase, class V, type 10A
chr5_-_104021919 1.947 ENSMUST00000031251.9
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr14_+_120275669 1.922 ENSMUST00000088419.6
ENSMUST00000167459.1
Mbnl2

muscleblind-like 2

chr13_-_81570640 1.868 ENSMUST00000109565.2
Gpr98
G protein-coupled receptor 98
chr6_+_128362919 1.713 ENSMUST00000073316.6
Foxm1
forkhead box M1
chr8_+_105170668 1.713 ENSMUST00000109395.1
ENSMUST00000109394.1
ENSMUST00000052209.2
ENSMUST00000109392.1
Cbfb



core binding factor beta



chr14_-_122465677 1.682 ENSMUST00000039118.6
Zic5
zinc finger protein of the cerebellum 5
chr13_-_23710714 1.681 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
Hfe


hemochromatosis


chr17_+_34203527 1.641 ENSMUST00000025197.5
Tap2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr10_-_41490335 1.627 ENSMUST00000019965.6
Smpd2
sphingomyelin phosphodiesterase 2, neutral
chr1_-_14310198 1.578 ENSMUST00000168081.2
ENSMUST00000027066.6
Eya1

eyes absent 1 homolog (Drosophila)

chrX_-_134161928 1.577 ENSMUST00000033611.4
Xkrx
X Kell blood group precursor related X linked
chr11_-_101551837 1.573 ENSMUST00000017290.4
Brca1
breast cancer 1
chr10_+_86022189 1.573 ENSMUST00000120344.1
ENSMUST00000117597.1
Fbxo7

F-box protein 7

chr7_-_65370908 1.571 ENSMUST00000032729.6
Tjp1
tight junction protein 1
chr16_-_5255923 1.486 ENSMUST00000139584.1
ENSMUST00000064635.5
Fam86

family with sequence similarity 86

chr5_-_104021799 1.452 ENSMUST00000119025.1
Hsd17b11
hydroxysteroid (17-beta) dehydrogenase 11
chr15_-_50889691 1.437 ENSMUST00000165201.2
ENSMUST00000184458.1
Trps1

trichorhinophalangeal syndrome I (human)

chr4_+_115000156 1.340 ENSMUST00000030490.6
Stil
Scl/Tal1 interrupting locus
chr11_-_3539228 1.318 ENSMUST00000075118.3
ENSMUST00000136243.1
ENSMUST00000170588.1
ENSMUST00000020721.8
Smtn



smoothelin



chr2_-_51934644 1.309 ENSMUST00000165313.1
Rbm43
RNA binding motif protein 43
chr2_+_71453276 1.292 ENSMUST00000037210.8
Metap1d
methionyl aminopeptidase type 1D (mitochondrial)
chr13_-_100616911 1.263 ENSMUST00000168772.1
ENSMUST00000163163.1
ENSMUST00000022137.7
Marveld2


MARVEL (membrane-associating) domain containing 2


chr13_+_5861489 1.258 ENSMUST00000000080.6
Klf6
Kruppel-like factor 6
chr4_+_115000174 1.219 ENSMUST00000129957.1
Stil
Scl/Tal1 interrupting locus
chr1_+_16688405 1.174 ENSMUST00000026881.4
Ly96
lymphocyte antigen 96
chrX_+_94636066 1.142 ENSMUST00000096368.3
Gspt2
G1 to S phase transition 2
chr17_-_30612613 1.135 ENSMUST00000167624.1
ENSMUST00000024823.6
Glo1

glyoxalase 1

chr16_+_43235856 1.113 ENSMUST00000146708.1
Zbtb20
zinc finger and BTB domain containing 20
chr13_+_96082158 1.111 ENSMUST00000185178.1
Gm17190
predicted gene 17190
chr9_-_114564315 1.105 ENSMUST00000111816.2
Trim71
tripartite motif-containing 71
chr3_+_89421619 1.094 ENSMUST00000094378.3
ENSMUST00000137793.1
Shc1

src homology 2 domain-containing transforming protein C1

chr14_+_60732906 1.062 ENSMUST00000162945.1
Spata13
spermatogenesis associated 13
chr8_+_128685654 1.057 ENSMUST00000090006.5
Itgb1
integrin beta 1 (fibronectin receptor beta)
chr2_+_128126030 0.983 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
Bcl2l11




BCL2-like 11 (apoptosis facilitator)




chr18_+_7869707 0.965 ENSMUST00000166062.1
ENSMUST00000169010.1
Wac

WW domain containing adaptor with coiled-coil

chr1_+_99772765 0.929 ENSMUST00000086738.3
Cntnap5b
contactin associated protein-like 5B
chr18_-_78142119 0.901 ENSMUST00000160639.1
Slc14a1
solute carrier family 14 (urea transporter), member 1
chr1_-_57406443 0.807 ENSMUST00000160837.1
ENSMUST00000161780.1
Tyw5

tRNA-yW synthesizing protein 5

chr10_-_64090241 0.804 ENSMUST00000133588.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr4_-_136886187 0.800 ENSMUST00000046384.8
C1qb
complement component 1, q subcomponent, beta polypeptide
chrX_+_150547375 0.766 ENSMUST00000066337.6
ENSMUST00000112715.1
Alas2

aminolevulinic acid synthase 2, erythroid

chr10_+_21882184 0.762 ENSMUST00000120509.1
Sgk1
serum/glucocorticoid regulated kinase 1
chr16_+_24393350 0.735 ENSMUST00000038053.6
Lpp
LIM domain containing preferred translocation partner in lipoma
chr16_-_24393588 0.700 ENSMUST00000181640.1
1110054M08Rik
RIKEN cDNA 1110054M08 gene
chr4_-_123139929 0.627 ENSMUST00000030404.4
Ppie
peptidylprolyl isomerase E (cyclophilin E)
chr1_-_159168642 0.587 ENSMUST00000077309.1
Gm4953
predicted pseudogene 4953
chr1_+_58393119 0.584 ENSMUST00000050552.8
Bzw1
basic leucine zipper and W2 domains 1
chr17_-_6782775 0.548 ENSMUST00000064234.6
Ezr
ezrin
chr1_+_187215737 0.528 ENSMUST00000160471.1
Gpatch2
G patch domain containing 2
chr10_+_126978690 0.496 ENSMUST00000105256.2
Ctdsp2
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 2
chr11_+_62820469 0.470 ENSMUST00000108703.1
Trim16
tripartite motif-containing 16
chr11_+_78245743 0.466 ENSMUST00000002133.8
Sdf2
stromal cell derived factor 2
chr1_+_57845534 0.394 ENSMUST00000169772.1
Spats2l
spermatogenesis associated, serine-rich 2-like
chr16_-_43664145 0.389 ENSMUST00000096065.4
Tigit
T cell immunoreceptor with Ig and ITIM domains
chr9_+_45042425 0.381 ENSMUST00000034600.4
Mpzl2
myelin protein zero-like 2
chr10_-_78352053 0.381 ENSMUST00000105388.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr7_+_19024387 0.332 ENSMUST00000153976.1
Sympk
symplekin
chr9_+_105053239 0.331 ENSMUST00000035177.8
ENSMUST00000149243.1
Mrpl3

mitochondrial ribosomal protein L3

chr8_-_78821136 0.330 ENSMUST00000130325.1
ENSMUST00000051867.6
Lsm6

LSM6 homolog, U6 small nuclear RNA associated (S. cerevisiae)

chr10_-_78351711 0.329 ENSMUST00000105390.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chrM_+_8600 0.328 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr10_-_18234930 0.315 ENSMUST00000052648.8
ENSMUST00000080860.6
ENSMUST00000173243.1
Ccdc28a


coiled-coil domain containing 28A


chr10_-_64090265 0.312 ENSMUST00000105439.1
Lrrtm3
leucine rich repeat transmembrane neuronal 3
chr9_+_35267857 0.272 ENSMUST00000034543.4
Rpusd4
RNA pseudouridylate synthase domain containing 4
chr1_-_184732616 0.263 ENSMUST00000048572.6
Hlx
H2.0-like homeobox
chr7_+_4460687 0.260 ENSMUST00000167298.1
ENSMUST00000171445.1
Eps8l1

EPS8-like 1

chr17_+_35424870 0.250 ENSMUST00000113879.3
H2-Q6
histocompatibility 2, Q region locus 6
chr4_-_107178282 0.248 ENSMUST00000058585.7
Tceanc2
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr9_+_64811313 0.246 ENSMUST00000038890.5
Dennd4a
DENN/MADD domain containing 4A
chr12_-_110695860 0.242 ENSMUST00000149189.1
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr4_-_72200833 0.242 ENSMUST00000102848.2
ENSMUST00000072695.6
ENSMUST00000107337.1
ENSMUST00000074216.7
Tle1



transducin-like enhancer of split 1, homolog of Drosophila E(spl)



chr11_+_69966896 0.230 ENSMUST00000151515.1
Cldn7
claudin 7
chr19_+_33822908 0.226 ENSMUST00000042061.6
Gm5519
predicted pseudogene 5519
chr16_+_92058270 0.213 ENSMUST00000047429.8
ENSMUST00000113975.2
Mrps6
Slc5a3
mitochondrial ribosomal protein S6
solute carrier family 5 (inositol transporters), member 3
chr7_-_16286744 0.203 ENSMUST00000150528.2
ENSMUST00000118976.2
ENSMUST00000146609.2
Ccdc9


coiled-coil domain containing 9


chr16_+_35938972 0.199 ENSMUST00000023622.6
ENSMUST00000114877.1
Parp9

poly (ADP-ribose) polymerase family, member 9

chr10_+_18235030 0.196 ENSMUST00000181897.1
Gm10827
predicted gene 10827
chrX_-_101222426 0.163 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
Snx12


sorting nexin 12


chrX_+_94367112 0.150 ENSMUST00000113898.1
Apoo
apolipoprotein O
chr7_-_80387935 0.149 ENSMUST00000080932.6
Fes
feline sarcoma oncogene
chr12_-_4477138 0.119 ENSMUST00000085814.3
Ncoa1
nuclear receptor coactivator 1
chr1_+_132008285 0.112 ENSMUST00000146432.1
Elk4
ELK4, member of ETS oncogene family
chrM_+_9452 0.100 ENSMUST00000082411.1
mt-Nd3
mitochondrially encoded NADH dehydrogenase 3
chr1_-_174921813 0.093 ENSMUST00000055294.3
Grem2
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr7_-_126396715 0.069 ENSMUST00000075671.4
Nfatc2ip
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein
chr7_+_83755904 0.059 ENSMUST00000051522.8
ENSMUST00000042280.7
Gm7964

predicted gene 7964

chr10_-_78351690 0.054 ENSMUST00000166360.1
Agpat3
1-acylglycerol-3-phosphate O-acyltransferase 3
chr18_-_70530138 0.052 ENSMUST00000161542.1
ENSMUST00000159389.1
Poli

polymerase (DNA directed), iota

chr3_+_95526777 0.015 ENSMUST00000015667.2
ENSMUST00000116304.2
Ctss

cathepsin S


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 3.5 GO:0006553 lysine metabolic process(GO:0006553)
1.0 3.1 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.8 2.4 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.7 2.9 GO:1903011 negative regulation of bone development(GO:1903011)
0.6 1.7 GO:0002578 negative regulation of antigen processing and presentation(GO:0002578)
0.5 1.6 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.5 2.0 GO:0003430 tolerance induction to self antigen(GO:0002513) growth plate cartilage chondrocyte growth(GO:0003430)
0.4 5.4 GO:0048664 neuron fate determination(GO:0048664)
0.4 1.6 GO:0051708 intracellular transport of viral protein in host cell(GO:0019060) symbiont intracellular protein transport in host(GO:0030581) cytosol to ER transport(GO:0046967) intracellular protein transport in other organism involved in symbiotic interaction(GO:0051708)
0.4 3.2 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.4 1.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.4 1.1 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.3 3.4 GO:0042447 hormone catabolic process(GO:0042447)
0.3 2.6 GO:0033504 floor plate development(GO:0033504)
0.3 2.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.3 0.8 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.3 1.6 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.2 2.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.2 1.0 GO:0001907 killing by symbiont of host cells(GO:0001907) induction of programmed cell death(GO:0012502) disruption by symbiont of host cell(GO:0044004) positive regulation of apoptotic process in other organism(GO:0044533) positive regulation by symbiont of host programmed cell death(GO:0052042) positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation by organism of programmed cell death in other organism involved in symbiotic interaction(GO:0052330) positive regulation by organism of apoptotic process in other organism involved in symbiotic interaction(GO:0052501) positive regulation of apoptotic process by virus(GO:0060139) apoptotic process involved in embryonic digit morphogenesis(GO:1902263) positive regulation of fibroblast apoptotic process(GO:2000271)
0.2 1.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.2 1.7 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.2 1.0 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.2 0.5 GO:1900041 intestinal D-glucose absorption(GO:0001951) negative regulation of interleukin-2 secretion(GO:1900041) terminal web assembly(GO:1902896)
0.2 0.2 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.2 1.6 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.1 0.9 GO:0015840 urea transport(GO:0015840) urea transmembrane transport(GO:0071918)
0.1 2.4 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 14.0 GO:0051592 response to calcium ion(GO:0051592)
0.1 1.1 GO:0061158 3'-UTR-mediated mRNA destabilization(GO:0061158)
0.1 0.5 GO:0070589 cell wall mannoprotein biosynthetic process(GO:0000032) mannoprotein metabolic process(GO:0006056) mannoprotein biosynthetic process(GO:0006057) cell wall glycoprotein biosynthetic process(GO:0031506) cell wall biogenesis(GO:0042546) cell wall macromolecule metabolic process(GO:0044036) cell wall macromolecule biosynthetic process(GO:0044038) chain elongation of O-linked mannose residue(GO:0044845) cellular component macromolecule biosynthetic process(GO:0070589) cell wall organization or biogenesis(GO:0071554)
0.1 2.5 GO:0031670 cellular response to nutrient(GO:0031670)
0.1 3.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.1 1.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.8 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.1 1.1 GO:1902993 positive regulation of beta-amyloid formation(GO:1902004) positive regulation of amyloid precursor protein catabolic process(GO:1902993)
0.1 0.5 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.1 2.7 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.1 1.7 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 1.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 0.2 GO:0015791 polyol transport(GO:0015791)
0.1 1.8 GO:0045620 negative regulation of lymphocyte differentiation(GO:0045620)
0.1 0.8 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 1.1 GO:0045907 positive regulation of vasoconstriction(GO:0045907)
0.0 0.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 1.9 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.2 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0 2.0 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 1.3 GO:0061028 establishment of endothelial barrier(GO:0061028)
0.0 1.6 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.2 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 2.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.6 GO:0045070 protein peptidyl-prolyl isomerization(GO:0000413) positive regulation of viral genome replication(GO:0045070)
0.0 2.4 GO:0009411 response to UV(GO:0009411)
0.0 1.1 GO:0046847 filopodium assembly(GO:0046847)
0.0 0.1 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0048262 determination of dorsal/ventral asymmetry(GO:0048262) determination of dorsal identity(GO:0048263)
0.0 2.0 GO:0098780 mitophagy in response to mitochondrial depolarization(GO:0098779) response to mitochondrial depolarisation(GO:0098780)
0.0 0.5 GO:2000134 negative regulation of G1/S transition of mitotic cell cycle(GO:2000134)
0.0 7.1 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway(GO:0007169)
0.0 1.7 GO:0001843 neural tube closure(GO:0001843) tube closure(GO:0060606)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 3.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.5 0.5 GO:0097454 Schwann cell microvillus(GO:0097454)
0.4 1.1 GO:0018444 translation release factor complex(GO:0018444)
0.4 1.1 GO:0034679 integrin alpha2-beta1 complex(GO:0034666) integrin alpha3-beta1 complex(GO:0034667) integrin alpha9-beta1 complex(GO:0034679)
0.3 1.7 GO:1990357 terminal web(GO:1990357)
0.3 3.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.2 1.6 GO:0042825 TAP complex(GO:0042825)
0.2 1.3 GO:0061689 paranodal junction(GO:0033010) tricellular tight junction(GO:0061689)
0.2 1.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 1.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.2 1.6 GO:0070531 BRCA1-A complex(GO:0070531)
0.1 2.9 GO:0005921 gap junction(GO:0005921)
0.1 0.5 GO:0031502 dolichyl-phosphate-mannose-protein mannosyltransferase complex(GO:0031502)
0.1 2.3 GO:0097546 ciliary base(GO:0097546)
0.1 8.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.2 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.0 3.4 GO:0005811 lipid particle(GO:0005811)
0.0 1.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 3.1 GO:0005901 caveola(GO:0005901)
0.0 21.8 GO:0005730 nucleolus(GO:0005730)
0.0 4.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 1.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 1.1 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.6 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 4.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 1.2 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 3.5 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.6 2.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.5 2.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.5 3.4 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.4 1.6 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
0.4 2.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.4 1.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 1.1 GO:0048408 epidermal growth factor binding(GO:0048408)
0.3 1.1 GO:0098634 protein binding involved in cell-matrix adhesion(GO:0098634) collagen binding involved in cell-matrix adhesion(GO:0098639)
0.2 1.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.2 1.7 GO:0039706 co-receptor binding(GO:0039706)
0.2 2.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.2 0.5 GO:0019966 interleukin-1 binding(GO:0019966)
0.2 0.9 GO:0015265 urea channel activity(GO:0015265)
0.1 4.7 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.1 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 1.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 3.5 GO:0042805 actinin binding(GO:0042805)
0.1 2.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.1 2.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 0.8 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 2.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 8.5 GO:0005178 integrin binding(GO:0005178)
0.1 0.5 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 1.1 GO:0035198 miRNA binding(GO:0035198)
0.1 1.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 3.1 GO:0005518 collagen binding(GO:0005518)
0.0 0.8 GO:0016594 glycine binding(GO:0016594)
0.0 0.5 GO:0044548 S100 protein binding(GO:0044548)
0.0 1.0 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0002135 CTP binding(GO:0002135)
0.0 0.2 GO:0015166 polyol transmembrane transporter activity(GO:0015166)
0.0 0.7 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.0 GO:0045502 dynein binding(GO:0045502)
0.0 12.1 GO:0005509 calcium ion binding(GO:0005509)
0.0 1.5 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.3 GO:0046977 TAP binding(GO:0046977)
0.0 2.9 GO:0030674 protein binding, bridging(GO:0030674)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0036122 BMP binding(GO:0036122)
0.0 0.6 GO:0016859 peptidyl-prolyl cis-trans isomerase activity(GO:0003755) cis-trans isomerase activity(GO:0016859)
0.0 1.1 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.8 GO:0000049 tRNA binding(GO:0000049)
0.0 1.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 0.6 GO:0050839 cell adhesion molecule binding(GO:0050839)
0.0 0.1 GO:0034987 immunoglobulin receptor binding(GO:0034987)