Motif ID: Irf4

Z-value: 0.686


Transcription factors associated with Irf4:

Gene SymbolEntrez IDGene Name
Irf4 ENSMUSG00000021356.3 Irf4



Activity profile for motif Irf4.

activity profile for motif Irf4


Sorted Z-values histogram for motif Irf4

Sorted Z-values for motif Irf4



Network of associatons between targets according to the STRING database.



First level regulatory network of Irf4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image


Top targets:


Showing 1 to 20 of 117 entries
PromoterScoreRefseqGene SymbolGene Name
chr3_+_90537242 7.068 ENSMUST00000098911.3
S100a16
S100 calcium binding protein A16
chr3_+_90537306 6.910 ENSMUST00000107335.1
S100a16
S100 calcium binding protein A16
chr1_-_163313661 5.401 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
Prrx1


paired related homeobox 1


chr3_-_142395661 3.508 ENSMUST00000029941.9
ENSMUST00000168967.2
ENSMUST00000090134.5
ENSMUST00000058626.8
Pdlim5



PDZ and LIM domain 5



chr11_-_77894096 3.461 ENSMUST00000017597.4
Pipox
pipecolic acid oxidase
chr10_+_128706251 3.221 ENSMUST00000054125.8
Pmel
premelanosome protein
chr19_-_58454580 3.126 ENSMUST00000129100.1
ENSMUST00000123957.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr6_-_87335758 3.122 ENSMUST00000042025.9
Antxr1
anthrax toxin receptor 1
chr19_-_24225015 2.861 ENSMUST00000099558.4
Tjp2
tight junction protein 2
chr19_-_58455161 2.788 ENSMUST00000135730.1
ENSMUST00000152507.1
Gfra1

glial cell line derived neurotrophic factor family receptor alpha 1

chr6_+_82041623 2.756 ENSMUST00000042974.8
Eva1a
eva-1 homolog A (C. elegans)
chr6_-_97060407 2.668 ENSMUST00000089295.4
Fam19a4
family with sequence similarity 19, member A4
chr6_-_39118211 2.663 ENSMUST00000038398.6
Parp12
poly (ADP-ribose) polymerase family, member 12
chr19_-_58455398 2.583 ENSMUST00000026076.7
Gfra1
glial cell line derived neurotrophic factor family receptor alpha 1
chr1_+_66468364 2.479 ENSMUST00000061620.9
Unc80
unc-80 homolog (C. elegans)
chr19_+_56397100 2.407 ENSMUST00000026062.9
Casp7
caspase 7
chr4_-_89311021 2.407 ENSMUST00000097981.4
Cdkn2b
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr1_+_61638819 2.400 ENSMUST00000138768.1
ENSMUST00000075374.3
Pard3b

par-3 partitioning defective 3 homolog B (C. elegans)

chr14_-_66124482 2.399 ENSMUST00000070515.1
Ephx2
epoxide hydrolase 2, cytoplasmic
chr7_-_141010759 2.354 ENSMUST00000026565.6
Ifitm3
interferon induced transmembrane protein 3

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 64 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 14.0 GO:0051592 response to calcium ion(GO:0051592)
0.0 7.1 GO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway(GO:0007169)
0.4 5.4 GO:0048664 neuron fate determination(GO:0048664)
1.2 3.5 GO:0006553 lysine metabolic process(GO:0006553)
0.3 3.4 GO:0042447 hormone catabolic process(GO:0042447)
0.4 3.2 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
1.0 3.1 GO:1903054 negative regulation of extracellular matrix organization(GO:1903054)
0.1 3.0 GO:0003301 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.7 2.9 GO:1903011 negative regulation of bone development(GO:1903011)
0.1 2.7 GO:0051930 regulation of sensory perception of pain(GO:0051930) regulation of sensory perception(GO:0051931)
0.3 2.6 GO:0033504 floor plate development(GO:0033504)
0.1 2.5 GO:0031670 cellular response to nutrient(GO:0031670)
0.8 2.4 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) olefin metabolic process(GO:1900673)
0.1 2.4 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.0 2.4 GO:0009411 response to UV(GO:0009411)
0.3 2.3 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.2 2.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 2.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.5 2.0 GO:0003430 tolerance induction to self antigen(GO:0002513) growth plate cartilage chondrocyte growth(GO:0003430)
0.0 2.0 GO:0015914 phospholipid transport(GO:0015914)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 29 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 21.8 GO:0005730 nucleolus(GO:0005730)
0.1 8.5 GO:0031225 anchored component of membrane(GO:0031225)
0.0 4.6 GO:0045211 postsynaptic membrane(GO:0045211)
0.0 4.0 GO:0005777 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 3.4 GO:0005811 lipid particle(GO:0005811)
0.6 3.2 GO:0032585 multivesicular body membrane(GO:0032585)
0.3 3.1 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 3.1 GO:0005901 caveola(GO:0005901)
0.1 2.9 GO:0005921 gap junction(GO:0005921)
0.0 2.6 GO:0005923 bicellular tight junction(GO:0005923) occluding junction(GO:0070160)
0.1 2.3 GO:0097546 ciliary base(GO:0097546)
0.3 1.7 GO:1990357 terminal web(GO:1990357)
0.2 1.6 GO:0042825 TAP complex(GO:0042825)
0.2 1.6 GO:0046581 intercellular canaliculus(GO:0046581)
0.2 1.6 GO:0070531 BRCA1-A complex(GO:0070531)
0.2 1.3 GO:0061689 paranodal junction(GO:0033010) tricellular tight junction(GO:0061689)
0.0 1.3 GO:0032587 ruffle membrane(GO:0032587)
0.2 1.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 1.2 GO:0005814 centriole(GO:0005814)
0.4 1.1 GO:0018444 translation release factor complex(GO:0018444)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 48 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 12.1 GO:0005509 calcium ion binding(GO:0005509)
0.1 8.5 GO:0005178 integrin binding(GO:0005178)
0.1 4.7 GO:0071837 HMG box domain binding(GO:0071837)
0.9 3.5 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.1 3.5 GO:0042805 actinin binding(GO:0042805)
0.5 3.4 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.1 3.1 GO:0005518 collagen binding(GO:0005518)
0.0 2.9 GO:0030674 protein binding, bridging(GO:0030674)
0.6 2.4 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.4 2.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 2.4 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.1 2.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.1 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.5 2.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 2.0 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 1.7 GO:0039706 co-receptor binding(GO:0039706)
0.4 1.6 GO:0023029 peptide antigen-transporting ATPase activity(GO:0015433) MHC class Ib protein binding(GO:0023029) tapasin binding(GO:0046980)
0.2 1.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 1.6 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.0 1.5 GO:0003684 damaged DNA binding(GO:0003684)