ISMARA results: Irx4

Motif ID: Irx4

Z-value: 0.244

Transcription factors associated with Irx4:

Gene Symbol	Entrez ID	Gene Name
Irx4	ENSMUSG00000021604.9	Irx4

Sorted Z-values for motif Irx4

Top targets:

Promoter	Score	Refseq	Gene Symbol	Gene Name
chr1_+_45311538	2.179	ENSMUST00000087883.6	Col3a1	collagen, type III, alpha 1
chr9_-_58202281	1.388	ENSMUST00000163897.1	Islr2	immunoglobulin superfamily containing leucine-rich repeat 2
chr6_-_3494587	0.929	ENSMUST00000049985.8	Hepacam2	HEPACAM family member 2
chr16_+_17146937	0.765	ENSMUST00000115706.1 ENSMUST00000069064.4	Ydjc	YdjC homolog (bacterial)
chr2_-_79908428	0.541	ENSMUST00000102652.3 ENSMUST00000102651.3	Pde1a	phosphodiesterase 1A, calmodulin-dependent
chr2_-_79908389	0.429	ENSMUST00000090756.4	Pde1a	phosphodiesterase 1A, calmodulin-dependent
chr8_+_84872105	0.384	ENSMUST00000136026.1 ENSMUST00000170296.1	Syce2	synaptonemal complex central element protein 2
chr4_+_48663502	0.345	ENSMUST00000030033.4	Murc	muscle-related coiled-coil protein
chr15_-_35938186	0.295	ENSMUST00000014457.8	Cox6c	cytochrome c oxidase subunit VIc
chr11_-_11970540	0.281	ENSMUST00000109653.1	Grb10	growth factor receptor bound protein 10
chr15_-_35938009	0.253	ENSMUST00000156915.1	Cox6c	cytochrome c oxidase subunit VIc
chr3_-_57651667	0.232	ENSMUST00000160959.1	Commd2	COMM domain containing 2
chr17_-_27133902	0.193	ENSMUST00000119227.1 ENSMUST00000025045.8	Uqcc2	ubiquinol-cytochrome c reductase complex assembly factor 2
chr6_-_83317589	0.083	ENSMUST00000005810.6	Mthfd2	methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
chr18_-_37178493	0.026	ENSMUST00000181887.1 ENSMUST00000180516.1	Gm10544	predicted gene 10544

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.2	GO:0060414	aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1	1.0	GO:0046069	cGMP catabolic process(GO:0046069)
0.0	0.3	GO:0055003	cardiac myofibril assembly(GO:0055003)
0.0	0.3	GO:0045719	negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0	1.4	GO:0045773	positive regulation of axon extension(GO:0045773)
0.0	0.4	GO:0007130	synaptonemal complex assembly(GO:0007130)
0.0	0.2	GO:0034551	respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)

Gene overrepresentation in cellular_component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.2	GO:0098643	fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1	0.4	GO:0000801	central element(GO:0000801)

Gene overrepresentation in molecular_function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.2	GO:0048407	platelet-derived growth factor binding(GO:0048407)
0.1	1.0	GO:0048101	calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0	0.8	GO:0043747	protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.0	0.1	GO:0004477	methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0	0.5	GO:0016676	cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0	0.3	GO:0001784	phosphotyrosine binding(GO:0001784)