Motif ID: Irx4

Z-value: 0.244


Transcription factors associated with Irx4:

Gene SymbolEntrez IDGene Name
Irx4 ENSMUSG00000021604.9 Irx4



Activity profile for motif Irx4.

activity profile for motif Irx4


Sorted Z-values histogram for motif Irx4

Sorted Z-values for motif Irx4



Network of associatons between targets according to the STRING database.



Top targets:


Promoter Score Refseq Gene Symbol Gene Name
chr1_+_45311538 2.179 ENSMUST00000087883.6
Col3a1
collagen, type III, alpha 1
chr9_-_58202281 1.388 ENSMUST00000163897.1
Islr2
immunoglobulin superfamily containing leucine-rich repeat 2
chr6_-_3494587 0.929 ENSMUST00000049985.8
Hepacam2
HEPACAM family member 2
chr16_+_17146937 0.765 ENSMUST00000115706.1
ENSMUST00000069064.4
Ydjc

YdjC homolog (bacterial)

chr2_-_79908428 0.541 ENSMUST00000102652.3
ENSMUST00000102651.3
Pde1a

phosphodiesterase 1A, calmodulin-dependent

chr2_-_79908389 0.429 ENSMUST00000090756.4
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr8_+_84872105 0.384 ENSMUST00000136026.1
ENSMUST00000170296.1
Syce2

synaptonemal complex central element protein 2

chr4_+_48663502 0.345 ENSMUST00000030033.4
Murc
muscle-related coiled-coil protein
chr15_-_35938186 0.295 ENSMUST00000014457.8
Cox6c
cytochrome c oxidase subunit VIc
chr11_-_11970540 0.281 ENSMUST00000109653.1
Grb10
growth factor receptor bound protein 10
chr15_-_35938009 0.253 ENSMUST00000156915.1
Cox6c
cytochrome c oxidase subunit VIc
chr3_-_57651667 0.232 ENSMUST00000160959.1
Commd2
COMM domain containing 2
chr17_-_27133902 0.193 ENSMUST00000119227.1
ENSMUST00000025045.8
Uqcc2

ubiquinol-cytochrome c reductase complex assembly factor 2

chr6_-_83317589 0.083 ENSMUST00000005810.6
Mthfd2
methylenetetrahydrofolate dehydrogenase (NAD+ dependent), methenyltetrahydrofolate cyclohydrolase
chr18_-_37178493 0.026 ENSMUST00000181887.1
ENSMUST00000180516.1
Gm10544

predicted gene 10544


Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 1.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.0 0.3 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 1.4 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.2 GO:0034551 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)

Gene overrepresentation in cellular_component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.4 GO:0000801 central element(GO:0000801)

Gene overrepresentation in molecular_function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 1.0 GO:0048101 calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.0 0.8 GO:0043747 protein-N-terminal asparagine amidohydrolase activity(GO:0008418) UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase activity(GO:0008759) iprodione amidohydrolase activity(GO:0018748) (3,5-dichlorophenylurea)acetate amidohydrolase activity(GO:0018749) 4'-(2-hydroxyisopropyl)phenylurea amidohydrolase activity(GO:0034571) didemethylisoproturon amidohydrolase activity(GO:0034573) N-isopropylacetanilide amidohydrolase activity(GO:0034576) N-cyclohexylformamide amidohydrolase activity(GO:0034781) isonicotinic acid hydrazide hydrolase activity(GO:0034876) cis-aconitamide amidase activity(GO:0034882) gamma-N-formylaminovinylacetate hydrolase activity(GO:0034885) N2-acetyl-L-lysine deacetylase activity(GO:0043747) O-succinylbenzoate synthase activity(GO:0043748) indoleacetamide hydrolase activity(GO:0043864) N-acetylcitrulline deacetylase activity(GO:0043909) N-acetylgalactosamine-6-phosphate deacetylase activity(GO:0047419) diacetylchitobiose deacetylase activity(GO:0052773) chitooligosaccharide deacetylase activity(GO:0052790)
0.0 0.1 GO:0004477 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.3 GO:0001784 phosphotyrosine binding(GO:0001784)