Motif ID: Isl1
Z-value: 0.432
Transcription factors associated with Isl1:
| Gene Symbol | Entrez ID | Gene Name |
|---|---|---|
| Isl1 | ENSMUSG00000042258.7 | Isl1 |
Activity-expression correlation:
| Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Isl1 | mm10_v2_chr13_-_116309639_116309699 | 0.14 | 2.9e-01 | Click! |
Top targets:
Showing 1 to 20 of 118 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 47 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 5.8 | GO:0048625 | myoblast fate commitment(GO:0048625) |
| 0.4 | 2.6 | GO:0032196 | transposition(GO:0032196) |
| 0.6 | 2.2 | GO:0014846 | esophagus smooth muscle contraction(GO:0014846) |
| 0.2 | 1.6 | GO:0021555 | midbrain-hindbrain boundary morphogenesis(GO:0021555) |
| 0.0 | 1.6 | GO:0051028 | mRNA transport(GO:0051028) |
| 0.5 | 1.4 | GO:0070315 | G1 to G0 transition involved in cell differentiation(GO:0070315) |
| 0.1 | 1.4 | GO:0060539 | diaphragm development(GO:0060539) |
| 0.1 | 1.4 | GO:0071803 | positive regulation of podosome assembly(GO:0071803) |
| 0.0 | 1.2 | GO:1902043 | positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043) |
| 0.4 | 1.1 | GO:0035880 | embryonic nail plate morphogenesis(GO:0035880) |
| 0.0 | 1.0 | GO:2001224 | positive regulation of neuron migration(GO:2001224) |
| 0.3 | 0.9 | GO:2000974 | negative regulation of pro-B cell differentiation(GO:2000974) |
| 0.0 | 0.9 | GO:0060325 | face morphogenesis(GO:0060325) |
| 0.0 | 0.8 | GO:0016339 | calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339) |
| 0.0 | 0.8 | GO:0006825 | copper ion transport(GO:0006825) |
| 0.0 | 0.8 | GO:0021680 | cerebellar Purkinje cell layer development(GO:0021680) |
| 0.1 | 0.7 | GO:0060164 | regulation of timing of neuron differentiation(GO:0060164) |
| 0.2 | 0.6 | GO:0072204 | cell-cell signaling involved in kidney development(GO:0060995) Wnt signaling pathway involved in kidney development(GO:0061289) canonical Wnt signaling pathway involved in metanephric kidney development(GO:0061290) cell-cell signaling involved in metanephros development(GO:0072204) |
| 0.1 | 0.6 | GO:1904936 | forebrain anterior/posterior pattern specification(GO:0021797) cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936) |
| 0.2 | 0.5 | GO:0042320 | regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) positive regulation of circadian sleep/wake cycle, sleep(GO:0045938) |
Gene overrepresentation in cellular_component category:
Showing 1 to 13 of 13 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 5.8 | GO:0070369 | beta-catenin-TCF7L2 complex(GO:0070369) |
| 0.1 | 1.4 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 1.2 | GO:0030315 | T-tubule(GO:0030315) |
| 0.0 | 1.1 | GO:0031463 | Cul3-RING ubiquitin ligase complex(GO:0031463) |
| 0.0 | 0.5 | GO:0032039 | integrator complex(GO:0032039) |
| 0.1 | 0.4 | GO:0005796 | Golgi lumen(GO:0005796) |
| 0.0 | 0.3 | GO:0065010 | extracellular membrane-bounded organelle(GO:0065010) |
| 0.0 | 0.3 | GO:0000159 | protein phosphatase type 2A complex(GO:0000159) |
| 0.0 | 0.3 | GO:0097546 | ciliary base(GO:0097546) |
| 0.0 | 0.2 | GO:1990357 | terminal web(GO:1990357) |
| 0.0 | 0.2 | GO:0031595 | nuclear proteasome complex(GO:0031595) |
| 0.0 | 0.1 | GO:0031095 | platelet dense tubular network membrane(GO:0031095) |
| 0.0 | 0.1 | GO:0098536 | deuterosome(GO:0098536) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 30 entries
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 5.8 | GO:0045295 | gamma-catenin binding(GO:0045295) |
| 0.0 | 2.6 | GO:0003727 | single-stranded RNA binding(GO:0003727) |
| 0.4 | 2.2 | GO:0008449 | N-acetylglucosamine-6-sulfatase activity(GO:0008449) |
| 0.0 | 1.8 | GO:0098811 | transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811) |
| 0.1 | 1.6 | GO:0048027 | mRNA 5'-UTR binding(GO:0048027) |
| 0.2 | 1.4 | GO:0031432 | titin binding(GO:0031432) |
| 0.1 | 1.4 | GO:0015197 | peptide transporter activity(GO:0015197) |
| 0.1 | 1.1 | GO:0004181 | metallocarboxypeptidase activity(GO:0004181) |
| 0.0 | 1.1 | GO:0002039 | p53 binding(GO:0002039) |
| 0.0 | 1.0 | GO:0030215 | semaphorin receptor binding(GO:0030215) |
| 0.0 | 0.9 | GO:0019003 | GDP binding(GO:0019003) |
| 0.2 | 0.8 | GO:0016724 | ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724) |
| 0.1 | 0.6 | GO:0016500 | protein-hormone receptor activity(GO:0016500) |
| 0.1 | 0.5 | GO:0019808 | polyamine binding(GO:0019808) |
| 0.1 | 0.5 | GO:0035727 | lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915) |
| 0.0 | 0.5 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.0 | 0.4 | GO:0005184 | neuropeptide hormone activity(GO:0005184) |
| 0.0 | 0.4 | GO:0070016 | armadillo repeat domain binding(GO:0070016) |
| 0.1 | 0.3 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.1 | 0.3 | GO:0047760 | butyrate-CoA ligase activity(GO:0047760) |
