Motif ID: Klf12_Klf14_Sp4
Z-value: 0.749



Transcription factors associated with Klf12_Klf14_Sp4:
Gene Symbol | Entrez ID | Gene Name |
---|---|---|
Klf12 | ENSMUSG00000072294.4 | Klf12 |
Klf14 | ENSMUSG00000073209.3 | Klf14 |
Sp4 | ENSMUSG00000025323.9 | Sp4 |
Activity-expression correlation:
Gene Symbol | Promoter | Pearson corr. coef. | P-value | Plot |
---|---|---|---|---|
Sp4 | mm10_v2_chr12_-_118301429_118301458 | 0.04 | 7.6e-01 | Click! |
Klf12 | mm10_v2_chr14_-_100149764_100149764 | -0.01 | 9.3e-01 | Click! |
Top targets:
Showing 1 to 20 of 200 entries
Gene overrepresentation in biological_process category:
Showing 1 to 20 of 526 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.6 | 8.3 | GO:0071257 | cellular response to electrical stimulus(GO:0071257) |
0.6 | 6.4 | GO:0030388 | fructose 1,6-bisphosphate metabolic process(GO:0030388) |
1.7 | 5.1 | GO:0030827 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
0.3 | 2.8 | GO:0045820 | negative regulation of glycolytic process(GO:0045820) |
0.7 | 2.7 | GO:0009597 | detection of virus(GO:0009597) |
0.5 | 2.7 | GO:0035743 | CD4-positive, alpha-beta T cell cytokine production(GO:0035743) T-helper 2 cell cytokine production(GO:0035745) |
0.2 | 2.6 | GO:0071378 | growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378) |
0.1 | 2.6 | GO:0007157 | heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157) |
0.5 | 2.5 | GO:0032485 | regulation of Ral protein signal transduction(GO:0032485) |
0.5 | 2.4 | GO:1904683 | regulation of metalloendopeptidase activity(GO:1904683) |
0.6 | 2.3 | GO:0072344 | rescue of stalled ribosome(GO:0072344) |
0.2 | 2.3 | GO:0019262 | N-acetylneuraminate catabolic process(GO:0019262) |
0.2 | 2.2 | GO:0061158 | 3'-UTR-mediated mRNA destabilization(GO:0061158) |
0.0 | 2.2 | GO:0045669 | positive regulation of osteoblast differentiation(GO:0045669) |
0.2 | 2.1 | GO:0045647 | negative regulation of erythrocyte differentiation(GO:0045647) |
0.1 | 2.0 | GO:0045653 | negative regulation of megakaryocyte differentiation(GO:0045653) |
0.2 | 1.9 | GO:0009181 | purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181) |
0.2 | 1.9 | GO:1902669 | positive regulation of axon extension involved in axon guidance(GO:0048842) positive regulation of axon guidance(GO:1902669) |
0.1 | 1.9 | GO:0006516 | glycoprotein catabolic process(GO:0006516) |
0.6 | 1.8 | GO:0035928 | rRNA import into mitochondrion(GO:0035928) |
Gene overrepresentation in cellular_component category:
Showing 1 to 20 of 174 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.3 | 6.6 | GO:0045334 | clathrin-coated endocytic vesicle(GO:0045334) |
0.5 | 4.9 | GO:0044327 | dendritic spine head(GO:0044327) |
0.0 | 4.7 | GO:0000139 | Golgi membrane(GO:0000139) |
0.1 | 4.4 | GO:0044815 | DNA packaging complex(GO:0044815) |
0.1 | 3.9 | GO:0032809 | neuronal cell body membrane(GO:0032809) |
0.1 | 3.8 | GO:0032994 | protein-lipid complex(GO:0032994) |
0.0 | 3.3 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
0.0 | 2.7 | GO:0070469 | respiratory chain(GO:0070469) |
0.0 | 2.6 | GO:0005769 | early endosome(GO:0005769) |
0.6 | 2.5 | GO:0045098 | type III intermediate filament(GO:0045098) |
0.0 | 2.4 | GO:0045335 | phagocytic vesicle(GO:0045335) |
0.2 | 2.3 | GO:0036513 | Derlin-1 retrotranslocation complex(GO:0036513) |
0.1 | 2.0 | GO:0000421 | autophagosome membrane(GO:0000421) |
0.0 | 1.9 | GO:0042383 | sarcolemma(GO:0042383) |
0.2 | 1.8 | GO:0031315 | extrinsic component of mitochondrial outer membrane(GO:0031315) |
0.1 | 1.8 | GO:0030992 | intraciliary transport particle B(GO:0030992) |
0.1 | 1.7 | GO:0032593 | insulin-responsive compartment(GO:0032593) |
0.4 | 1.6 | GO:1990590 | ATF1-ATF4 transcription factor complex(GO:1990590) |
0.0 | 1.6 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
0.1 | 1.5 | GO:0000137 | Golgi cis cisterna(GO:0000137) |
Gene overrepresentation in molecular_function category:
Showing 1 to 20 of 330 entries
Log-likelihood per target | Total log-likelihood | Term | Description |
---|---|---|---|
0.1 | 13.1 | GO:0051015 | actin filament binding(GO:0051015) |
1.1 | 6.7 | GO:0004332 | fructose-bisphosphate aldolase activity(GO:0004332) |
0.1 | 5.0 | GO:0005125 | cytokine activity(GO:0005125) |
0.0 | 3.8 | GO:0003714 | transcription corepressor activity(GO:0003714) |
0.1 | 3.6 | GO:0043015 | gamma-tubulin binding(GO:0043015) |
0.1 | 3.2 | GO:0071889 | 14-3-3 protein binding(GO:0071889) |
0.4 | 2.8 | GO:0043262 | adenosine-diphosphatase activity(GO:0043262) |
0.3 | 2.7 | GO:0008121 | ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors(GO:0016679) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681) |
0.0 | 2.7 | GO:0005088 | Ras guanyl-nucleotide exchange factor activity(GO:0005088) |
0.0 | 2.6 | GO:0017124 | SH3 domain binding(GO:0017124) |
0.8 | 2.3 | GO:0045127 | N-acetylglucosamine kinase activity(GO:0045127) |
0.0 | 2.3 | GO:0050839 | cell adhesion molecule binding(GO:0050839) |
0.4 | 2.1 | GO:0000213 | tRNA-intron endonuclease activity(GO:0000213) endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892) |
0.3 | 2.1 | GO:0008321 | Ral guanyl-nucleotide exchange factor activity(GO:0008321) |
0.2 | 2.0 | GO:0008191 | metalloendopeptidase inhibitor activity(GO:0008191) |
0.6 | 1.8 | GO:0036361 | racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661) |
0.4 | 1.8 | GO:0004563 | beta-N-acetylhexosaminidase activity(GO:0004563) |
0.4 | 1.8 | GO:0004792 | thiosulfate sulfurtransferase activity(GO:0004792) |
0.2 | 1.8 | GO:0050291 | sphingosine N-acyltransferase activity(GO:0050291) |
0.1 | 1.8 | GO:0022889 | L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889) |