Motif ID: Klf15

Z-value: 1.358


Transcription factors associated with Klf15:

Gene SymbolEntrez IDGene Name
Klf15 ENSMUSG00000030087.5 Klf15

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf15mm10_v2_chr6_+_90462562_904625870.498.1e-05Click!


Activity profile for motif Klf15.

activity profile for motif Klf15


Sorted Z-values histogram for motif Klf15

Sorted Z-values for motif Klf15



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf15

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr1_-_56971762 16.193 ENSMUST00000114415.3
 Satb2
special AT-rich sequence binding protein 2
chr18_-_89769479 11.741 ENSMUST00000097495.3
 Dok6
docking protein 6
chr17_+_46297917 10.238 ENSMUST00000166617.1
ENSMUST00000170271.1
 Dlk2

delta-like 2 homolog (Drosophila)

chr1_-_56972437 9.593 ENSMUST00000042857.7
 Satb2
special AT-rich sequence binding protein 2
chr18_-_66291770 9.155 ENSMUST00000130300.1
 Ccbe1
collagen and calcium binding EGF domains 1
chr7_+_46396439 9.111 ENSMUST00000025202.6
 Kcnc1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr11_+_24076529 9.091 ENSMUST00000148087.1
 Gm12063
predicted gene 12063
chr2_-_5714490 8.240 ENSMUST00000044009.7
 Camk1d
calcium/calmodulin-dependent protein kinase ID
chr4_+_97777780 7.966 ENSMUST00000107062.2
ENSMUST00000052018.5
ENSMUST00000107057.1
 Nfia


nuclear factor I/A


chr6_-_148444336 7.826 ENSMUST00000060095.8
ENSMUST00000100772.3
 Tmtc1

transmembrane and tetratricopeptide repeat containing 1

chr11_+_98348404 7.818 ENSMUST00000078694.6
 Ppp1r1b
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr11_+_69765970 7.604 ENSMUST00000108642.1
ENSMUST00000156932.1
 Zbtb4

zinc finger and BTB domain containing 4

chr11_+_69765899 7.444 ENSMUST00000108640.1
ENSMUST00000108639.1
 Zbtb4

zinc finger and BTB domain containing 4

chr7_+_126776939 7.421 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
 Ypel3






yippee-like 3 (Drosophila)






chr3_+_117575268 7.289 ENSMUST00000039564.6
 4833424O15Rik
RIKEN cDNA 4833424O15 gene
chr1_-_72536930 6.306 ENSMUST00000047786.5
 March4
membrane-associated ring finger (C3HC4) 4
chr19_+_5740885 6.275 ENSMUST00000081496.5
 Ltbp3
latent transforming growth factor beta binding protein 3
chr11_+_50602072 6.028 ENSMUST00000040523.8
 Adamts2
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr9_+_45430293 5.896 ENSMUST00000034592.8
 Dscaml1
Down syndrome cell adhesion molecule like 1
chr5_-_65492984 5.836 ENSMUST00000139122.1
 Smim14
small integral membrane protein 14

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 142 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.6 25.8 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
2.3 13.5 GO:1903056 regulation of lens fiber cell differentiation(GO:1902746) positive regulation of lens fiber cell differentiation(GO:1902748) regulation of melanosome organization(GO:1903056)
0.4 11.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.3 11.5 GO:0060074 synapse maturation(GO:0060074)
0.4 10.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.3 10.2 GO:0045746 negative regulation of Notch signaling pathway(GO:0045746)
2.3 9.2 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.2 9.1 GO:1901381 positive regulation of potassium ion transmembrane transport(GO:1901381)
1.2 8.2 GO:0060267 positive regulation of respiratory burst(GO:0060267)
2.6 7.8 GO:0007621 negative regulation of female receptivity(GO:0007621)
1.8 7.4 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
1.5 7.4 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.3 7.0 GO:0006491 N-glycan processing(GO:0006491)
2.2 6.6 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
2.1 6.4 GO:0071544 diphosphoinositol polyphosphate metabolic process(GO:0071543) diphosphoinositol polyphosphate catabolic process(GO:0071544)
2.1 6.3 GO:1902460 regulation of mesenchymal stem cell proliferation(GO:1902460) positive regulation of mesenchymal stem cell proliferation(GO:1902462)
0.4 6.0 GO:0030574 collagen catabolic process(GO:0030574)
0.7 5.9 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.7 5.9 GO:0016338 calcium-independent cell-cell adhesion via plasma membrane cell-adhesion molecules(GO:0016338)
0.6 5.9 GO:0006691 leukotriene metabolic process(GO:0006691)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 71 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.2 18.9 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 18.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.2 11.7 GO:0042734 presynaptic membrane(GO:0042734)
0.3 11.6 GO:0097440 apical dendrite(GO:0097440)
0.1 11.5 GO:0030175 filopodium(GO:0030175)
0.0 11.3 GO:0043025 neuronal cell body(GO:0043025)
0.3 9.1 GO:0030673 axolemma(GO:0030673)
0.0 8.4 GO:0045211 postsynaptic membrane(GO:0045211)
0.1 7.6 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 7.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.1 6.3 GO:0031256 leading edge membrane(GO:0031256)
0.1 5.7 GO:0005795 Golgi stack(GO:0005795)
0.1 5.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
1.7 5.0 GO:0005595 collagen type XII trimer(GO:0005595) anchoring collagen complex(GO:0030934)
0.1 5.0 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 4.9 GO:0031225 anchored component of membrane(GO:0031225)
0.4 4.5 GO:0000124 SAGA complex(GO:0000124)
0.0 4.5 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.2 4.4 GO:0097228 sperm principal piece(GO:0097228)
0.1 4.4 GO:0005930 axoneme(GO:0005930) ciliary plasm(GO:0097014)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 101 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 18.0 GO:0070412 R-SMAD binding(GO:0070412)
0.4 15.5 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.6 15.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.4 15.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.2 11.7 GO:0005158 insulin receptor binding(GO:0005158)
0.1 9.4 GO:0008083 growth factor activity(GO:0008083)
0.1 9.2 GO:0005518 collagen binding(GO:0005518)
0.3 9.1 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
2.6 7.8 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.6 7.4 GO:0070636 single-strand selective uracil DNA N-glycosylase activity(GO:0017065) nicotinamide riboside hydrolase activity(GO:0070635) nicotinic acid riboside hydrolase activity(GO:0070636) deoxyribonucleoside 5'-monophosphate N-glycosidase activity(GO:0070694)
0.8 7.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 6.6 GO:0001102 RNA polymerase II activating transcription factor binding(GO:0001102)
1.1 6.4 GO:0008486 diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486)
0.0 6.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 5.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.9 5.4 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429) corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.1 5.0 GO:0019003 GDP binding(GO:0019003)
0.0 5.0 GO:0017137 Rab GTPase binding(GO:0017137)
0.7 4.8 GO:0097322 7SK snRNA binding(GO:0097322)
0.2 4.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)