Motif ID: Klf6_Patz1

Z-value: 2.162

Transcription factors associated with Klf6_Patz1:

Gene SymbolEntrez IDGene Name
Klf6 ENSMUSG00000000078.6 Klf6
Patz1 ENSMUSG00000020453.11 Patz1

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf6mm10_v2_chr13_+_5861489_5861501-0.401.9e-03Click!
Patz1mm10_v2_chr11_+_3290300_32904570.104.4e-01Click!


Activity profile for motif Klf6_Patz1.

activity profile for motif Klf6_Patz1


Sorted Z-values histogram for motif Klf6_Patz1

Sorted Z-values for motif Klf6_Patz1



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf6_Patz1

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr11_-_102296618 22.804 ENSMUST00000107132.2
ENSMUST00000073234.2
 Atxn7l3

ataxin 7-like 3

chr7_+_44310213 19.217 ENSMUST00000107938.1
 Shank1
SH3/ankyrin domain gene 1
chr10_-_127534540 17.775 ENSMUST00000095266.2
 Nxph4
neurexophilin 4
chr5_+_37028329 17.368 ENSMUST00000173836.1
 Jakmip1
janus kinase and microtubule interacting protein 1
chr1_-_172057573 17.047 ENSMUST00000059794.3
 Nhlh1
nescient helix loop helix 1
chr1_+_136131382 14.299 ENSMUST00000075164.4
 Kif21b
kinesin family member 21B
chr5_-_138279960 13.890 ENSMUST00000014089.7
ENSMUST00000161827.1
 Gpc2

glypican 2 (cerebroglycan)

chr7_+_29289300 13.823 ENSMUST00000048187.4
 Ppp1r14a
protein phosphatase 1, regulatory (inhibitor) subunit 14A
chr9_-_106656081 13.280 ENSMUST00000023959.7
 Grm2
glutamate receptor, metabotropic 2
chr2_-_84886692 13.198 ENSMUST00000054514.5
ENSMUST00000151799.1
 Rtn4rl2

reticulon 4 receptor-like 2

chr17_+_28142267 12.340 ENSMUST00000043503.3
 Scube3
signal peptide, CUB domain, EGF-like 3
chr7_+_126950837 12.241 ENSMUST00000106332.1
 Sez6l2
seizure related 6 homolog like 2
chr2_-_24763047 12.100 ENSMUST00000100348.3
ENSMUST00000041342.5
ENSMUST00000114447.1
ENSMUST00000102939.2
ENSMUST00000070864.7
 Cacna1b




calcium channel, voltage-dependent, N type, alpha 1B subunit




chr7_+_126950687 12.073 ENSMUST00000106333.1
 Sez6l2
seizure related 6 homolog like 2
chr7_+_44384604 11.649 ENSMUST00000130707.1
ENSMUST00000130844.1
 Syt3

synaptotagmin III

chr10_-_127060163 11.555 ENSMUST00000040307.5
 March9
membrane-associated ring finger (C3HC4) 9
chr6_-_85502858 11.486 ENSMUST00000161546.1
ENSMUST00000161078.1
 Fbxo41

F-box protein 41

chr4_+_116877376 11.428 ENSMUST00000044823.3
 Zswim5
zinc finger SWIM-type containing 5
chr11_+_101468164 11.276 ENSMUST00000001347.6
 Rnd2
Rho family GTPase 2
chr9_-_107710475 11.061 ENSMUST00000080560.3
 Sema3f
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 722 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.1 40.3 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
1.9 38.3 GO:1903861 regulation of dendrite extension(GO:1903859) positive regulation of dendrite extension(GO:1903861)
1.4 32.9 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
1.0 28.3 GO:0016578 histone deubiquitination(GO:0016578)
1.9 24.3 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.6 22.6 GO:0007520 myoblast fusion(GO:0007520)
0.8 21.2 GO:0048843 negative regulation of axon extension involved in axon guidance(GO:0048843)
0.8 20.7 GO:0042220 response to cocaine(GO:0042220)
1.9 20.4 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
1.4 19.3 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
6.4 19.2 GO:0046959 habituation(GO:0046959)
2.3 18.5 GO:0035608 protein deglutamylation(GO:0035608)
3.1 18.4 GO:0021636 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637)
0.6 18.2 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.6 17.8 GO:2001222 regulation of neuron migration(GO:2001222)
0.5 17.1 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 16.8 GO:0042787 protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0042787)
0.9 16.7 GO:0034643 establishment of mitochondrion localization, microtubule-mediated(GO:0034643) mitochondrion transport along microtubule(GO:0047497)
0.9 15.8 GO:2000369 regulation of clathrin-mediated endocytosis(GO:2000369)
1.0 15.2 GO:0007252 I-kappaB phosphorylation(GO:0007252)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 253 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 60.2 GO:0070382 exocytic vesicle(GO:0070382)
0.1 38.7 GO:0043025 neuronal cell body(GO:0043025)
1.7 36.0 GO:0044300 cerebellar mossy fiber(GO:0044300)
1.1 34.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.6 29.6 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.4 29.0 GO:0043198 dendritic shaft(GO:0043198)
0.1 26.5 GO:0045211 postsynaptic membrane(GO:0045211)
0.5 25.1 GO:0030426 growth cone(GO:0030426)
0.3 24.9 GO:0055037 recycling endosome(GO:0055037)
2.4 24.2 GO:0044327 dendritic spine head(GO:0044327)
0.7 24.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.4 23.1 GO:0072686 mitotic spindle(GO:0072686)
0.9 22.0 GO:0071565 nBAF complex(GO:0071565)
1.8 21.6 GO:0000124 SAGA complex(GO:0000124)
0.7 20.9 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.6 20.1 GO:0035371 microtubule plus-end(GO:0035371)
0.2 19.9 GO:0030027 lamellipodium(GO:0030027)
1.6 19.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.5 18.3 GO:0016529 sarcoplasmic reticulum(GO:0016529)
1.0 16.5 GO:0034706 voltage-gated sodium channel complex(GO:0001518) sodium channel complex(GO:0034706)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 414 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.6 37.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
1.5 36.8 GO:0017075 syntaxin-1 binding(GO:0017075)
0.9 36.6 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.2 33.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630)
0.4 31.6 GO:0002039 p53 binding(GO:0002039)
0.2 30.8 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
2.1 30.0 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.5 29.4 GO:0004712 protein serine/threonine/tyrosine kinase activity(GO:0004712)
0.4 25.1 GO:0003777 microtubule motor activity(GO:0003777)
0.7 25.0 GO:0045499 chemorepellent activity(GO:0045499)
3.1 24.7 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 24.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
5.9 23.6 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.2 23.3 GO:0017124 SH3 domain binding(GO:0017124)
1.3 22.9 GO:0050811 GABA receptor binding(GO:0050811)
0.2 22.7 GO:0017137 Rab GTPase binding(GO:0017137)
0.9 21.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.5 20.5 GO:0045296 cadherin binding(GO:0045296)
0.6 19.0 GO:0034930 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) heparan sulfate 2-O-sulfotransferase activity(GO:0004394) HNK-1 sulfotransferase activity(GO:0016232) heparan sulfate 6-O-sulfotransferase activity(GO:0017095) trans-9R,10R-dihydrodiolphenanthrene sulfotransferase activity(GO:0018721) 1-phenanthrol sulfotransferase activity(GO:0018722) 3-phenanthrol sulfotransferase activity(GO:0018723) 4-phenanthrol sulfotransferase activity(GO:0018724) trans-3,4-dihydrodiolphenanthrene sulfotransferase activity(GO:0018725) 9-phenanthrol sulfotransferase activity(GO:0018726) 2-phenanthrol sulfotransferase activity(GO:0018727) phenanthrol sulfotransferase activity(GO:0019111) 1-hydroxypyrene sulfotransferase activity(GO:0034930) proteoglycan sulfotransferase activity(GO:0050698) cholesterol sulfotransferase activity(GO:0051922) hydroxyjasmonate sulfotransferase activity(GO:0080131)
1.0 18.1 GO:0050321 tau-protein kinase activity(GO:0050321)