Motif ID: Klf7

Z-value: 0.591


Transcription factors associated with Klf7:

Gene SymbolEntrez IDGene Name
Klf7 ENSMUSG00000025959.7 Klf7

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Klf7mm10_v2_chr1_-_64121456_641214910.498.5e-05Click!


Activity profile for motif Klf7.

activity profile for motif Klf7


Sorted Z-values histogram for motif Klf7

Sorted Z-values for motif Klf7



Network of associatons between targets according to the STRING database.



First level regulatory network of Klf7

PNG image of the network

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Top targets:


Showing 1 to 20 of 87 entries
PromoterScoreRefseqGene SymbolGene Name
chr2_-_156312470 6.005 ENSMUST00000079125.6
Scand1
SCAN domain-containing 1
chr6_-_88875035 4.812 ENSMUST00000145944.1
Podxl2
podocalyxin-like 2
chrY_+_897782 4.169 ENSMUST00000055032.7
Kdm5d
lysine (K)-specific demethylase 5D
chr3_+_28263205 3.764 ENSMUST00000159236.2
Tnik
TRAF2 and NCK interacting kinase
chr5_-_137741601 3.543 ENSMUST00000119498.1
ENSMUST00000061789.7
Nyap1

neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1

chr5_+_137778849 3.309 ENSMUST00000126126.1
ENSMUST00000031739.4
Ppp1r35

protein phosphatase 1, regulatory subunit 35

chr6_-_88874597 3.186 ENSMUST00000061262.4
ENSMUST00000140455.1
ENSMUST00000145780.1
Podxl2


podocalyxin-like 2


chr12_-_4592927 3.027 ENSMUST00000170816.1
Gm3625
predicted gene 3625
chr7_-_74013676 3.015 ENSMUST00000026896.4
St8sia2
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
chr4_+_107830958 2.986 ENSMUST00000106731.2
Lrp8
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr12_+_49382791 2.912 ENSMUST00000179669.1
Foxg1
forkhead box G1
chr12_+_49383007 2.587 ENSMUST00000021333.3
Foxg1
forkhead box G1
chr15_-_102722150 2.272 ENSMUST00000023818.3
Calcoco1
calcium binding and coiled coil domain 1
chr15_-_102722120 2.143 ENSMUST00000171838.1
Calcoco1
calcium binding and coiled coil domain 1
chr7_-_28766469 2.001 ENSMUST00000085851.5
ENSMUST00000032815.4
Nfkbib

nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, beta

chr6_+_52714219 1.903 ENSMUST00000138040.1
ENSMUST00000129660.1
Tax1bp1

Tax1 (human T cell leukemia virus type I) binding protein 1

chr15_+_30172570 1.881 ENSMUST00000081728.5
Ctnnd2
catenin (cadherin associated protein), delta 2
chr3_+_106721893 1.623 ENSMUST00000106736.2
ENSMUST00000154973.1
ENSMUST00000131330.1
ENSMUST00000150513.1
Lrif1



ligand dependent nuclear receptor interacting factor 1



chr6_+_125039760 1.512 ENSMUST00000140131.1
ENSMUST00000032480.7
Ing4

inhibitor of growth family, member 4

chr18_+_67133713 1.467 ENSMUST00000076605.7
Gnal
guanine nucleotide binding protein, alpha stimulating, olfactory type

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 44 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 8.0 GO:0050901 leukocyte tethering or rolling(GO:0050901)
1.8 5.5 GO:0021852 pyramidal neuron migration(GO:0021852)
0.8 4.2 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.0 4.1 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.8 3.8 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 3.5 GO:0014065 phosphatidylinositol 3-kinase signaling(GO:0014065)
0.0 3.3 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
1.0 3.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.3 3.0 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.2 3.0 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 2.1 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.3 2.0 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 1.9 GO:0060997 dendritic spine morphogenesis(GO:0060997)
0.2 1.5 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.1 1.5 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.5 1.4 GO:0070375 ERK5 cascade(GO:0070375)
0.0 1.4 GO:0006970 response to osmotic stress(GO:0006970)
0.2 1.3 GO:0006537 glutamate biosynthetic process(GO:0006537) proline biosynthetic process(GO:0006561)
0.3 1.2 GO:0061428 positive regulation of oocyte development(GO:0060282) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 1.2 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)

Gene overrepresentation in cellular_component category:

Showing 1 to 14 of 14 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.1 7.7 GO:0055037 recycling endosome(GO:0055037)
0.1 3.1 GO:0035861 site of double-strand break(GO:0035861)
0.0 2.8 GO:0005875 microtubule associated complex(GO:0005875)
0.0 2.6 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 1.9 GO:0043204 perikaryon(GO:0043204)
0.0 1.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 1.5 GO:0000123 histone acetyltransferase complex(GO:0000123)
0.2 1.2 GO:0033010 paranodal junction(GO:0033010)
0.0 1.0 GO:0016605 PML body(GO:0016605)
0.2 0.9 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.7 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.1 0.6 GO:0097255 R2TP complex(GO:0097255)
0.1 0.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 28 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 7.8 GO:0003713 transcription coactivator activity(GO:0003713)
0.2 4.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.6 4.2 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 3.8 GO:0004702 receptor signaling protein serine/threonine kinase activity(GO:0004702)
0.7 3.0 GO:0038025 reelin receptor activity(GO:0038025)
0.5 3.0 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 3.0 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.1 2.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 2.9 GO:0043130 ubiquitin binding(GO:0043130)
0.3 2.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.5 1.5 GO:0050827 toxin receptor binding(GO:0050827)
0.0 1.4 GO:0004707 MAP kinase activity(GO:0004707)
0.1 1.3 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.3 1.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739) tubulin deacetylase activity(GO:0042903)
0.2 1.2 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 0.9 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.2 0.8 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.8 GO:0030552 cAMP binding(GO:0030552)
0.2 0.7 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.7 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)