Motif ID: Maf_Nrl

Z-value: 0.608

Transcription factors associated with Maf_Nrl:

Gene SymbolEntrez IDGene Name
Maf ENSMUSG00000055435.6 Maf
Nrl ENSMUSG00000040632.9 Nrl

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafmm10_v2_chr8_-_115707778_115707794-0.201.4e-01Click!


Activity profile for motif Maf_Nrl.

activity profile for motif Maf_Nrl


Sorted Z-values histogram for motif Maf_Nrl

Sorted Z-values for motif Maf_Nrl



Network of associatons between targets according to the STRING database.



First level regulatory network of Maf_Nrl

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_-_103853199 9.018 ENSMUST00000033229.3
 Hbb-y
hemoglobin Y, beta-like embryonic chain
chr7_-_103843154 7.249 ENSMUST00000063957.4
 Hbb-bh1
hemoglobin Z, beta-like embryonic chain
chr2_+_120476911 5.210 ENSMUST00000110716.1
ENSMUST00000028748.6
ENSMUST00000090028.5
ENSMUST00000110719.2
 Capn3



calpain 3



chr4_-_135573623 4.105 ENSMUST00000105855.1
 Grhl3
grainyhead-like 3 (Drosophila)
chr10_+_56377300 2.961 ENSMUST00000068581.7
 Gja1
gap junction protein, alpha 1
chr4_+_155839724 2.921 ENSMUST00000030947.3
 Mxra8
matrix-remodelling associated 8
chr19_+_20601958 2.915 ENSMUST00000087638.3
 Aldh1a1
aldehyde dehydrogenase family 1, subfamily A1
chr10_+_87859255 2.873 ENSMUST00000105300.2
 Igf1
insulin-like growth factor 1
chr2_-_130397525 2.787 ENSMUST00000028897.7
 Cpxm1
carboxypeptidase X 1 (M14 family)
chr10_+_87859062 2.625 ENSMUST00000095360.4
 Igf1
insulin-like growth factor 1
chr19_+_55894508 2.619 ENSMUST00000142291.1
 Tcf7l2
transcription factor 7 like 2, T cell specific, HMG box
chr9_+_65141154 2.554 ENSMUST00000034961.4
 Igdcc3
immunoglobulin superfamily, DCC subclass, member 3
chr5_+_147188678 2.446 ENSMUST00000065382.5
 Gsx1
GS homeobox 1
chr1_+_90203980 2.370 ENSMUST00000065587.4
ENSMUST00000159654.1
 Ackr3

atypical chemokine receptor 3

chr13_+_113342548 2.257 ENSMUST00000078163.7
 BC067074
cDNA sequence BC067074
chr19_-_20727533 2.235 ENSMUST00000025656.3
 Aldh1a7
aldehyde dehydrogenase family 1, subfamily A7
chr13_+_72632597 2.118 ENSMUST00000172353.1
 Irx2
Iroquois related homeobox 2 (Drosophila)
chr5_-_24730635 1.944 ENSMUST00000068693.5
 Wdr86
WD repeat domain 86
chr11_-_75422524 1.897 ENSMUST00000125982.1
ENSMUST00000137103.1
 Serpinf1

serine (or cysteine) peptidase inhibitor, clade F, member 1

chr11_+_76202084 1.893 ENSMUST00000169560.1
 Fam57a
family with sequence similarity 57, member A

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 115 entries
Log-likelihood per target Total log-likelihoodTermDescription
3.3 16.3 GO:0015671 oxygen transport(GO:0015671)
1.6 6.5 GO:0060741 prostate gland stromal morphogenesis(GO:0060741)
1.7 5.2 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.5 4.1 GO:0061436 establishment of skin barrier(GO:0061436)
0.5 4.1 GO:0021984 adenohypophysis development(GO:0021984)
1.1 3.3 GO:0048014 Tie signaling pathway(GO:0048014)
1.0 3.0 GO:0003104 positive regulation of glomerular filtration(GO:0003104) cell communication by chemical coupling(GO:0010643)
0.7 2.9 GO:0042905 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.2 2.7 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.3 2.6 GO:0048625 myoblast fate commitment(GO:0048625)
0.3 2.3 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 2.3 GO:0050885 neuromuscular process controlling balance(GO:0050885)
0.3 2.2 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.6 1.8 GO:0048818 embryonic nail plate morphogenesis(GO:0035880) positive regulation of hair follicle maturation(GO:0048818) positive regulation of catagen(GO:0051795) frontal suture morphogenesis(GO:0060364)
0.3 1.8 GO:0051461 protein import into peroxisome matrix, docking(GO:0016560) regulation of corticotropin secretion(GO:0051459) positive regulation of corticotropin secretion(GO:0051461)
0.3 1.7 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 1.7 GO:0090005 negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.4 1.6 GO:1900623 positive regulation of keratinocyte proliferation(GO:0010838) positive regulation of hyaluronan biosynthetic process(GO:1900127) regulation of monocyte aggregation(GO:1900623) positive regulation of monocyte aggregation(GO:1900625)
0.0 1.6 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.5 1.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 59 entries
Log-likelihood per target Total log-likelihoodTermDescription
2.0 16.3 GO:0005833 hemoglobin complex(GO:0005833)
1.4 5.5 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454) insulin-like growth factor ternary complex(GO:0042567)
0.1 4.7 GO:0030315 T-tubule(GO:0030315)
0.3 3.5 GO:0005916 fascia adherens(GO:0005916)
0.4 2.6 GO:0071664 beta-catenin-TCF7L2 complex(GO:0070369) catenin-TCF7L2 complex(GO:0071664)
0.0 2.6 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.0 GO:0031225 anchored component of membrane(GO:0031225)
0.1 1.9 GO:0043203 axon hillock(GO:0043203)
0.4 1.8 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 1.7 GO:0005884 actin filament(GO:0005884)
0.0 1.7 GO:0005770 late endosome(GO:0005770)
0.2 1.6 GO:0030008 TRAPP complex(GO:0030008)
0.5 1.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.3 GO:0016010 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 1.3 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.2 1.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.1 1.2 GO:0030057 desmosome(GO:0030057)
0.1 1.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 1.1 GO:0005902 microvillus(GO:0005902)
0.0 1.1 GO:0045335 phagocytic vesicle(GO:0045335)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 89 entries
Log-likelihood per target Total log-likelihoodTermDescription
4.1 16.3 GO:0031721 hemoglobin alpha binding(GO:0031721)
0.2 5.5 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.7 5.2 GO:0031432 titin binding(GO:0031432)
0.3 4.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 4.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.0 4.0 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.6 3.0 GO:0071253 connexin binding(GO:0071253)
0.5 2.9 GO:0001758 retinal dehydrogenase activity(GO:0001758) 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 2.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.1 2.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.8 2.4 GO:0016494 C-X-C chemokine receptor activity(GO:0016494) C-X-C chemokine binding(GO:0019958)
0.0 2.3 GO:0004714 transmembrane receptor protein tyrosine kinase activity(GO:0004714)
0.1 2.2 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.2 2.1 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 2.1 GO:0008432 JUN kinase binding(GO:0008432)
0.1 2.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.4 1.8 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.8 GO:0005522 profilin binding(GO:0005522)
0.0 1.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)