Motif ID: Mafb

Z-value: 0.869


Transcription factors associated with Mafb:

Gene SymbolEntrez IDGene Name
Mafb ENSMUSG00000074622.3 Mafb

Activity-expression correlation:

Gene SymbolPromoterPearson corr. coef.P-valuePlot
Mafbmm10_v2_chr2_-_160367057_1603670730.541.2e-05Click!


Activity profile for motif Mafb.

activity profile for motif Mafb


Sorted Z-values histogram for motif Mafb

Sorted Z-values for motif Mafb



Network of associatons between targets according to the STRING database.



First level regulatory network of Mafb

PNG image of the network

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Top targets:


Showing 1 to 20 of 200 entries
PromoterScoreRefseqGene SymbolGene Name
chr7_+_130936172 11.299 ENSMUST00000006367.7
 Htra1
HtrA serine peptidase 1
chr13_-_85127514 8.930 ENSMUST00000179230.1
 Gm4076
predicted gene 4076
chr15_-_81843699 7.090 ENSMUST00000092020.2
 Gm8444
predicted gene 8444
chr7_-_120202104 6.442 ENSMUST00000033198.5
 Crym
crystallin, mu
chr2_+_170731807 5.751 ENSMUST00000029075.4
 Dok5
docking protein 5
chr6_+_120773633 5.666 ENSMUST00000112682.2
 Slc25a18
solute carrier family 25 (mitochondrial carrier), member 18
chr9_-_48911067 4.914 ENSMUST00000003826.7
 Htr3a
5-hydroxytryptamine (serotonin) receptor 3A
chr11_-_116307168 4.873 ENSMUST00000124281.1
 Exoc7
exocyst complex component 7
chr12_-_24493656 4.813 ENSMUST00000073088.2
 Gm16372
predicted pseudogene 16372
chr1_-_5070281 4.636 ENSMUST00000147158.1
ENSMUST00000118000.1
 Rgs20

regulator of G-protein signaling 20

chr2_-_127482499 4.620 ENSMUST00000088538.5
 Kcnip3
Kv channel interacting protein 3, calsenilin
chr18_+_65873478 4.618 ENSMUST00000025395.8
ENSMUST00000173530.1
 Grp

gastrin releasing peptide

chr7_-_141010759 4.535 ENSMUST00000026565.6
 Ifitm3
interferon induced transmembrane protein 3
chr1_+_9547948 4.523 ENSMUST00000144177.1
 Adhfe1
alcohol dehydrogenase, iron containing, 1
chr15_+_82252397 4.224 ENSMUST00000136948.1
 1500009C09Rik
RIKEN cDNA 1500009C09 gene
chr4_+_102421518 3.952 ENSMUST00000106904.2
 Pde4b
phosphodiesterase 4B, cAMP specific
chr10_+_40349265 3.936 ENSMUST00000044672.4
ENSMUST00000095743.2
 Cdk19

cyclin-dependent kinase 19

chr19_-_5510467 3.826 ENSMUST00000070172.4
 Snx32
sorting nexin 32
chr2_-_168741898 3.595 ENSMUST00000109176.1
ENSMUST00000178504.1
 Atp9a

ATPase, class II, type 9A

chr5_+_140735526 3.540 ENSMUST00000120630.2
 Amz1
archaelysin family metallopeptidase 1

Gene Ontology Analysis

Gene overrepresentation in biological_process category:

Showing 1 to 20 of 105 entries
Log-likelihood per target Total log-likelihoodTermDescription
1.9 11.3 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
1.3 6.4 GO:0070327 thyroid hormone transport(GO:0070327)
0.5 5.8 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.8 5.5 GO:0051547 regulation of keratinocyte migration(GO:0051547) positive regulation of keratinocyte migration(GO:0051549)
1.6 4.9 GO:0007210 serotonin receptor signaling pathway(GO:0007210)
0.4 4.9 GO:0035635 entry of bacterium into host cell(GO:0035635) regulation of entry of bacterium into host cell(GO:2000535)
0.4 4.6 GO:0090244 Wnt signaling pathway involved in somitogenesis(GO:0090244)
0.2 4.6 GO:0048266 behavioral response to pain(GO:0048266)
0.1 4.6 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 4.6 GO:0006818 hydrogen transport(GO:0006818)
0.2 4.5 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 4.5 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.3 4.0 GO:1901898 negative regulation of relaxation of muscle(GO:1901078) negative regulation of relaxation of cardiac muscle(GO:1901898)
0.5 3.6 GO:0001542 ovulation from ovarian follicle(GO:0001542) positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300) positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1 3.5 GO:1900026 positive regulation of substrate adhesion-dependent cell spreading(GO:1900026)
0.4 3.4 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 3.3 GO:0006342 chromatin silencing(GO:0006342)
0.6 3.2 GO:0051012 microtubule sliding(GO:0051012) negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.0 3.1 GO:0072583 clathrin-mediated endocytosis(GO:0072583)
0.3 3.0 GO:0035999 tetrahydrofolate interconversion(GO:0035999)

Gene overrepresentation in cellular_component category:

Showing 1 to 20 of 47 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.0 10.7 GO:0031012 extracellular matrix(GO:0031012)
0.1 9.6 GO:0034703 cation channel complex(GO:0034703)
0.0 5.3 GO:0005764 lytic vacuole(GO:0000323) lysosome(GO:0005764)
0.2 4.6 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.0 3.9 GO:0055037 recycling endosome(GO:0055037)
0.3 3.6 GO:0032584 growth cone membrane(GO:0032584)
0.3 3.5 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.1 3.3 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 3.3 GO:0019898 extrinsic component of membrane(GO:0019898)
0.0 3.2 GO:0072686 mitotic spindle(GO:0072686)
0.0 3.0 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 2.8 GO:0005581 collagen trimer(GO:0005581)
0.2 2.7 GO:0042101 T cell receptor complex(GO:0042101)
0.2 2.6 GO:0005922 connexon complex(GO:0005922)
0.2 2.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 2.4 GO:0071564 npBAF complex(GO:0071564)
0.4 2.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.3 2.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 2.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 2.0 GO:0005905 clathrin-coated pit(GO:0005905)

Gene overrepresentation in molecular_function category:

Showing 1 to 20 of 87 entries
Log-likelihood per target Total log-likelihoodTermDescription
0.5 11.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.8 6.4 GO:0070324 thyroid hormone binding(GO:0070324)
0.1 5.9 GO:0097472 cyclin-dependent protein serine/threonine kinase activity(GO:0004693) cyclin-dependent protein kinase activity(GO:0097472)
0.1 5.9 GO:0015459 potassium channel regulator activity(GO:0015459)
0.0 5.7 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 5.1 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
1.2 4.9 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378) serotonin receptor activity(GO:0099589)
0.2 4.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 4.6 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.5 4.1 GO:0015643 toxic substance binding(GO:0015643)
0.1 4.1 GO:0030552 cAMP binding(GO:0030552)
0.0 3.9 GO:0016614 oxidoreductase activity, acting on CH-OH group of donors(GO:0016614)
1.3 3.8 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.0 3.8 GO:0008234 cysteine-type peptidase activity(GO:0008234)
0.1 3.7 GO:0005158 insulin receptor binding(GO:0005158)
0.2 3.6 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 3.6 GO:0001221 transcription cofactor binding(GO:0001221)
0.3 3.1 GO:0032050 clathrin heavy chain binding(GO:0032050)
1.0 3.0 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 3.0 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)